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Volumn 173, Issue 2, 2016, Pages 405-426

Toxic Effects of Titanium Dioxide Nanoparticles and Titanium Dioxide Bulk Salt in the Liver and Blood of Male Sprague-Dawley Rats Assessed by Different Assays

Author keywords

Histological changes; Lipid peroxidation; Liver function tests; Micronucleus assay; Nanoparticles; Oxidative stress; TiO2

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TITANIUM DIOXIDE; TITANIUM DIOXIDE NANOPARTICLE; BIOLOGICAL MARKER; NANOPARTICLE; OXIDOREDUCTASE; TITANIUM;

EID: 84961783404     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-016-0677-4     Document Type: Article
Times cited : (44)

References (117)
  • 1
    • 84986618619 scopus 로고    scopus 로고
    • The effects of manufactured nanoparticles on fish physiology, reproduction and behaviour. In: Faculty of Science. School of Biomedical and Biological Sciences
    • Ramsden CS (2012) The effects of manufactured nanoparticles on fish physiology, reproduction and behaviour. In: Faculty of Science. School of Biomedical and Biological Sciences, p 255
    • (2012)
    • Ramsden, C.S.1
  • 3
    • 78650519473 scopus 로고    scopus 로고
    • ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells
    • COI: 1:CAS:528:DC%2BC3cXhs1agsLbN, PID: 21092754
    • Shukla RK, Sharma V, Pandey AK, Singh S, Sultana S, Dhawan A (2011) ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells. Toxicol in Vitro 25(1):231–241. doi:10.1016/j.tiv.2010.11.008
    • (2011) Toxicol in Vitro , vol.25 , Issue.1 , pp. 231-241
    • Shukla, R.K.1    Sharma, V.2    Pandey, A.K.3    Singh, S.4    Sultana, S.5    Dhawan, A.6
  • 4
    • 77952551025 scopus 로고    scopus 로고
    • Spleen injury and apoptotic pathway in mice caused by titanium dioxide nanoparticles
    • COI: 1:CAS:528:DC%2BC3cXlsFansL4%3D, PID: 20381595
    • Li N, Duan Y, Hong M, Zheng L, Fei M, Zhao X, Wang J, Cui Y, Liu H, Cai J, Gong S, Wang H, Hong F (2010) Spleen injury and apoptotic pathway in mice caused by titanium dioxide nanoparticles. Toxicol Lett 195(2–3):161–168. doi:10.1016/j.toxlet.2010.03.1116
    • (2010) Toxicol Lett , vol.195 , Issue.2-3 , pp. 161-168
    • Li, N.1    Duan, Y.2    Hong, M.3    Zheng, L.4    Fei, M.5    Zhao, X.6    Wang, J.7    Cui, Y.8    Liu, H.9    Cai, J.10    Gong, S.11    Wang, H.12    Hong, F.13
  • 5
    • 84986575120 scopus 로고    scopus 로고
    • Histopathological effects of ZnO nanoparticles on liver and heart tissues in Wistar rats
    • COI: 1:CAS:528:DC%2BC3sXhtlyiu7%2FL
    • Saman S, Moradhaseli S, Shokouhian A, Ghorbani M (2013) Histopathological effects of ZnO nanoparticles on liver and heart tissues in Wistar rats. Adv Biores 4(2):83–88
    • (2013) Adv Biores , vol.4 , Issue.2 , pp. 83-88
    • Saman, S.1    Moradhaseli, S.2    Shokouhian, A.3    Ghorbani, M.4
  • 6
    • 84986618615 scopus 로고    scopus 로고
    • Queen’s University, Kingston, Ontario
    • Philbrook NA, Investigating the effects of nanoparticles on reproduction and development in Drosophila melanogaster and CD-1 mice. 2010, Queen’s University, Kingston, Ontario, Canada p91.
    • (2010) Canada , vol.p91
    • Philbrook, N.A.1
  • 7
    • 0037112831 scopus 로고    scopus 로고
    • 2 mediated by solar light
    • COI: 1:CAS:528:DC%2BD38XoslyqtL0%3D
    • 2 mediated by solar light. Catal Today 76(2–4):201–207. doi:10.1016/S0920-5861(02)00219-5
    • (2002) Catal Today , vol.76 , Issue.2-4 , pp. 201-207
    • Higarashi, M.M.1    Jardim, W.F.2
  • 9
    • 1842425986 scopus 로고    scopus 로고
    • 2-assisted photocatalytic degradation of azo dyes in aqueous solution: kinetic and mechanistic investigations: A review
    • COI: 1:CAS:528:DC%2BD2cXisl2ksL4%3D
    • 2-assisted photocatalytic degradation of azo dyes in aqueous solution: kinetic and mechanistic investigations: A review. Appl Catal B Environ 49(1):1–14. doi:10.1016/j.apcatb.2003.11.010
    • (2004) Appl Catal B Environ , vol.49 , Issue.1 , pp. 1-14
    • Konstantinou, I.K.1    Albanis, T.A.2
  • 11
    • 77149169765 scopus 로고    scopus 로고
    • Synthesis, structure and optical properties of zinc oxide hexagonal microprisms
    • COI: 1:CAS:528:DC%2BC3cXhvFyiu7c%3D
    • Kumari L, Li WZ (2010) Synthesis, structure and optical properties of zinc oxide hexagonal microprisms. Cryst Res Technol 45(3):311–315. doi:10.1002/crat.200900600
    • (2010) Cryst Res Technol , vol.45 , Issue.3 , pp. 311-315
    • Kumari, L.1    Li, W.Z.2
  • 15
    • 36849014692 scopus 로고    scopus 로고
    • We’re history—titanium dioxide: from black sand to white pigment
    • Gussman N (2005) We’re history—titanium dioxide: from black sand to white pigment. Chem Eng Prog 101(6):64–64
    • (2005) Chem Eng Prog , vol.101 , Issue.6 , pp. 64
    • Gussman, N.1
  • 16
    • 0034532004 scopus 로고    scopus 로고
    • Determination of titanium dioxide in foods using inductively coupled plasma optical emission spectrometry
    • COI: 1:CAS:528:DC%2BD3MXlvFWqtw%3D%3D, PID: 11219079
    • Lomer MCE, Thompson RPH, Commisso J, Keen CL, Powell JJ (2000) Determination of titanium dioxide in foods using inductively coupled plasma optical emission spectrometry. Analyst 125(12):2339–2343. doi:10.1039/B006285P
    • (2000) Analyst , vol.125 , Issue.12 , pp. 2339-2343
    • Lomer, M.C.E.1    Thompson, R.P.H.2    Commisso, J.3    Keen, C.L.4    Powell, J.J.5
  • 17
  • 21
    • 34347259223 scopus 로고    scopus 로고
    • Toxic effects of nanoparticles and nanomaterials: Implications for public health, risk assessment and the public perception of nanotechnology
    • Handy RD, Shaw BJ (2007) Toxic effects of nanoparticles and nanomaterials: Implications for public health, risk assessment and the public perception of nanotechnology. Health Risk Soc 9(2):125–144. doi:10.1080/13698570701306807
    • (2007) Health Risk Soc , vol.9 , Issue.2 , pp. 125-144
    • Handy, R.D.1    Shaw, B.J.2
  • 22
    • 44449147673 scopus 로고    scopus 로고
    • Manufactured nanoparticles: Their uptake and effects on fish—a mechanistic analysis
    • COI: 1:CAS:528:DC%2BD1cXmsVKrsb0%3D, PID: 18408995
    • Handy R, Henry T, Scown T, Johnston B, Tyler C (2008) Manufactured nanoparticles: Their uptake and effects on fish—a mechanistic analysis. Ecotoxicology 17(5):396–409. doi:10.1007/s10646-008-0205-1
    • (2008) Ecotoxicology , vol.17 , Issue.5 , pp. 396-409
    • Handy, R.1    Henry, T.2    Scown, T.3    Johnston, B.4    Tyler, C.5
  • 23
    • 84986580972 scopus 로고    scopus 로고
    • Uptake and effects of nanoparticles in fish. In: Biological Sciences. University of Exeter
    • Scown T (2009) Uptake and effects of nanoparticles in fish. In: Biological Sciences. University of Exeter, p 363
    • (2009)
    • Scown, T.1
  • 24
    • 84899002047 scopus 로고    scopus 로고
    • Investigation toxicity properties of zinc oxide nanoparticles on liver enzymes in male rat
    • COI: 1:CAS:528:DC%2BC3sXjsFyru7g%3D
    • Fazilati M (2013) Investigation toxicity properties of zinc oxide nanoparticles on liver enzymes in male rat. European J Exp Biol 3(1):97–103
    • (2013) European J Exp Biol , vol.3 , Issue.1 , pp. 97-103
    • Fazilati, M.1
  • 25
    • 33847678943 scopus 로고    scopus 로고
    • Nanoparticles: pharmacological and toxicological significance
    • COI: 1:CAS:528:DC%2BD2sXisVeis70%3D, PID: 17245366
    • Medina C, Santos-Martinez M, Radomski A, Corrigan O, Radomski M (2007) Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol 150(5):552–558
    • (2007) Br J Pharmacol , vol.150 , Issue.5 , pp. 552-558
    • Medina, C.1    Santos-Martinez, M.2    Radomski, A.3    Corrigan, O.4    Radomski, M.5
  • 26
    • 84855796444 scopus 로고    scopus 로고
    • In vitro methods for nanotoxicity assessment: advantages and applications
    • COI: 1:CAS:528:DC%2BC3MXlsVOntbg%3D
    • Takhar P, Mahant S (2011) In vitro methods for nanotoxicity assessment: advantages and applications. Arch Appl Sci Res 3(2):389–403
    • (2011) Arch Appl Sci Res , vol.3 , Issue.2 , pp. 389-403
    • Takhar, P.1    Mahant, S.2
  • 27
    • 84885728931 scopus 로고    scopus 로고
    • Histologic and apoptotic changes induced by titanium dioxide nanoparticles in the livers of rats
    • PID: 24143098
    • Alarifi S, Ali D, Al-Doaiss AA, Ali BA, Ahmed M, Al-Khedhairy AA (2013) Histologic and apoptotic changes induced by titanium dioxide nanoparticles in the livers of rats. Int J Nanomedicine 8:3937–3943. doi:10.2147/ijn.s47174
    • (2013) Int J Nanomedicine , vol.8 , pp. 3937-3943
    • Alarifi, S.1    Ali, D.2    Al-Doaiss, A.A.3    Ali, B.A.4    Ahmed, M.5    Al-Khedhairy, A.A.6
  • 29
    • 67449103004 scopus 로고    scopus 로고
    • Influence of different sizes of titanium dioxide nanoparticles on hepatic and renal functions in rats with correlation to oxidative stress
    • COI: 1:CAS:528:DC%2BD1MXmslCjsLw%3D
    • Liang G, Pu Y, Yin L, Liu R, Ye B, Su Y, Li Y (2009) Influence of different sizes of titanium dioxide nanoparticles on hepatic and renal functions in rats with correlation to oxidative stress. J Toxic Environ Health A 72(11–12):740–745. doi:10.1080/15287390902841516
    • (2009) J Toxic Environ Health A , vol.72 , Issue.11-12 , pp. 740-745
    • Liang, G.1    Pu, Y.2    Yin, L.3    Liu, R.4    Ye, B.5    Su, Y.6    Li, Y.7
  • 30
    • 0022742360 scopus 로고
    • International Federation of Clinical Chemistry (IFCC): approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes part 3. IFCC method for alanine aminotransferase
    • COI: 1:STN:280:DyaL283otValtQ%3D%3D, PID: 3734711
    • Bergmeyer HU, Horder M, Rej R (1986) International Federation of Clinical Chemistry (IFCC): approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes part 3. IFCC method for alanine aminotransferase. J Clin Chem Clin Biochem 24(7):481–495
    • (1986) J Clin Chem Clin Biochem , vol.24 , Issue.7 , pp. 481-495
    • Bergmeyer, H.U.1    Horder, M.2    Rej, R.3
  • 31
    • 84986616471 scopus 로고    scopus 로고
    • Blood AST, ALT and UREA/BUN level analysis
    • Sher Y, Hung M (2013) Blood AST, ALT and UREA/BUN level analysis. Bio-Protocol 3:e931
    • (2013) Bio-Protocol , vol.3
    • Sher, Y.1    Hung, M.2
  • 32
    • 0022749157 scopus 로고
    • International Federation of Clinical Chemistry (IFCC): approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes part 2. IFCC method for aspartate aminotransferase
    • COI: 1:STN:280:DyaL283otValug%3D%3D, PID: 3734712
    • Bergmeyer HU, Horder M, Rej R (1986) International Federation of Clinical Chemistry (IFCC): approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes part 2. IFCC method for aspartate aminotransferase. J Clin Chem Clin Biochem 24(7):497–510
    • (1986) J Clin Chem Clin Biochem , vol.24 , Issue.7 , pp. 497-510
    • Bergmeyer, H.U.1    Horder, M.2    Rej, R.3
  • 34
    • 80055043870 scopus 로고    scopus 로고
    • Effects of sodium selenite in cadmium chloride induced hepatoxicity in male Sprague-Dawley rats
    • COI: 1:CAS:528:DC%2BC3MXhs1ansr%2FI
    • Jabeen F, Chaudhry AS (2011) Effects of sodium selenite in cadmium chloride induced hepatoxicity in male Sprague-Dawley rats. Pakistan J Zool 43:957–965
    • (2011) Pakistan J Zool , vol.43 , pp. 957-965
    • Jabeen, F.1    Chaudhry, A.S.2
  • 35
    • 0026628935 scopus 로고
    • Interactions of a series of coumarins with reactive oxygen species: scavenging of superoxide, hypochlorous acid and hydroxyl radicals
    • PID: 1322662
    • Payá M, Halliwell B, Hoult JRS (1992) Interactions of a series of coumarins with reactive oxygen species: scavenging of superoxide, hypochlorous acid and hydroxyl radicals. Biochem Pharmacol 44(2):205–214. doi:10.1016/0006-2952(92)90002-Z
    • (1992) Biochem Pharmacol , vol.44 , Issue.2 , pp. 205-214
    • Payá, M.1    Halliwell, B.2    Hoult, J.R.S.3
  • 36
    • 49349097354 scopus 로고    scopus 로고
    • A new genus of Monimiaceae from the Atlantic coastal forest in south-eastern Brazil
    • Peixoto AL, Pereira-Moura MVL (2008) A new genus of Monimiaceae from the Atlantic coastal forest in south-eastern Brazil. Kew Bull 63(1):137–141
    • (2008) Kew Bull , vol.63 , Issue.1 , pp. 137-141
    • Peixoto, A.L.1    Pereira-Moura, M.V.L.2
  • 37
    • 0016275313 scopus 로고
    • Glutathione S-transferases the first enzymatic step in mercapturic acid formation
    • COI: 1:CAS:528:DyaE2MXltlahtg%3D%3D, PID: 4436300
    • Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferases the first enzymatic step in mercapturic acid formation. J Biol Chem 249(22):7130–7139
    • (1974) J Biol Chem , vol.249 , Issue.22 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 38
    • 0037834643 scopus 로고    scopus 로고
    • The bioaccumulation of nonyphenol and its adverse effect on the liver of rainbow trout (Onchorynchus mykiss)
    • COI: 1:CAS:528:DC%2BD3sXksVyrt7k%3D, PID: 12804523
    • Uguz C, Iscan M, Ergüven A, Isgor B, Togan I (2003) The bioaccumulation of nonyphenol and its adverse effect on the liver of rainbow trout (Onchorynchus mykiss). Environ Res 92(3):262–270. doi:10.1016/S0013-9351(03)00033-1
    • (2003) Environ Res , vol.92 , Issue.3 , pp. 262-270
    • Uguz, C.1    Iscan, M.2    Ergüven, A.3    Isgor, B.4    Togan, I.5
  • 39
    • 0016151122 scopus 로고
    • Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite
    • COI: 1:CAS:528:DyaE2cXkslejtLk%3D, PID: 4831804
    • Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR (1974) Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11(3):151–169
    • (1974) Pharmacology , vol.11 , Issue.3 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3    Gillette, J.R.4
  • 41
    • 0036325318 scopus 로고    scopus 로고
    • Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonella foenum graecum)
    • COI: 1:CAS:528:DC%2BD38XltV2jsrs%3D, PID: 12190123
    • Genet S, Kale RK, Baquer NZ (2002) Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonella foenum graecum). Mol Cell Biochem 236(1–2):7–12. doi:10.1023/A:1016103131408
    • (2002) Mol Cell Biochem , vol.236 , Issue.1-2 , pp. 7-12
    • Genet, S.1    Kale, R.K.2    Baquer, N.Z.3
  • 42
    • 84986603809 scopus 로고    scopus 로고
    • A study of some effects of aqueous extract of neem (Azadirachta indica) leaves on the lead acetate induced neurotoxicity in the superficial layers of superior colliculus of adult Wistar rats (Rattus norvegicus)
    • Bamidele FP, Ajibade AJ, Oyewo EB, Hannah AO (2013) A study of some effects of aqueous extract of neem (Azadirachta indica) leaves on the lead acetate induced neurotoxicity in the superficial layers of superior colliculus of adult Wistar rats (Rattus norvegicus). British J Pharm Res 3(2):217–231
    • (2013) British J Pharm Res , vol.3 , Issue.2 , pp. 217-231
    • Bamidele, F.P.1    Ajibade, A.J.2    Oyewo, E.B.3    Hannah, A.O.4
  • 44
    • 0016437314 scopus 로고
    • The micronucleus test
    • COI: 1:CAS:528:DyaE2MXhtVOjs7Y%3D
    • Schmid W (1975) The micronucleus test. Mutat Res Environ Mutagen Related Subjects 31(1):9–15. doi:10.1016/0165-1161(75)90058-8
    • (1975) Mutat Res Environ Mutagen Related Subjects , vol.31 , Issue.1 , pp. 9-15
    • Schmid, W.1
  • 45
    • 84955644903 scopus 로고    scopus 로고
    • Oral toxic exposure of titanium dioxide nanoparticles on serum biochemical changes in adult male Wistar rats
    • COI: 1:CAS:528:DC%2BC28XhtVChsbbM
    • Vasantharaja D, Ramalingam V, Aadinaath Reddy G (2015) Oral toxic exposure of titanium dioxide nanoparticles on serum biochemical changes in adult male Wistar rats. Nanomedicine Journal 2(1):46–53
    • (2015) Nanomedicine Journal , vol.2 , Issue.1 , pp. 46-53
    • Vasantharaja, D.1    Ramalingam, V.2    Aadinaath Reddy, G.3
  • 46
    • 84986540886 scopus 로고
    • In: FAO nutrition meetings report series no. 46 A: toxicological evaluation of some food colours, emulsifiers, stabilizers, anti-caking agents and certain other substances
    • W.H.O (1969) In: FAO nutrition meetings report series no. 46 A: toxicological evaluation of some food colours, emulsifiers, stabilizers, anti-caking agents and certain other substances. WHO/FOOD ADD/70.36
    • (1969) WHO/FOOD ADD/70.36
  • 47
    • 1342267646 scopus 로고    scopus 로고
    • Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles
    • COI: 1:CAS:528:DC%2BD2cXht1Kluro%3D, PID: 14600271
    • Bermudez E, Mangum JB, Wong BA, Asgharian B, Hext PM, Warheit DB, Everitt JI (2004) Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77(2):347–357. doi:10.1093/toxsci/kfh019
    • (2004) Toxicol Sci , vol.77 , Issue.2 , pp. 347-357
    • Bermudez, E.1    Mangum, J.B.2    Wong, B.A.3    Asgharian, B.4    Hext, P.M.5    Warheit, D.B.6    Everitt, J.I.7
  • 48
    • 34147148170 scopus 로고    scopus 로고
    • Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm
    • COI: 1:CAS:528:DC%2BD2sXjvFWnur0%3D, PID: 17431489
    • Grassian VH, O’Shaughnessy PT, Adamcakova-Dodd A, Pettibone JM, Thorne PS (2007) Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Environ Health Perspect 115(3):397–402. doi:10.1289/ehp.9469
    • (2007) Environ Health Perspect , vol.115 , Issue.3 , pp. 397-402
    • Grassian, V.H.1    O’Shaughnessy, P.T.2    Adamcakova-Dodd, A.3    Pettibone, J.M.4    Thorne, P.S.5
  • 49
    • 65849444104 scopus 로고    scopus 로고
    • Influence of intranasal instilled titanium dioxide nanoparticles on monoaminergic neurotransmitters of female mice at different exposure time
    • COI: 1:CAS:528:DC%2BD1cXkvVajt7o%3D
    • Wang JX, Li YF, Zhou GQ, Li B, Jiao F, Chen CY, Gao YX, Zhao YL, Chai ZF (2007) Influence of intranasal instilled titanium dioxide nanoparticles on monoaminergic neurotransmitters of female mice at different exposure time. Chinese J Prev Med 41(2):91–95
    • (2007) Chinese J Prev Med , vol.41 , Issue.2 , pp. 91-95
    • Wang, J.X.1    Li, Y.F.2    Zhou, G.Q.3    Li, B.4    Jiao, F.5    Chen, C.Y.6    Gao, Y.X.7    Zhao, Y.L.8    Chai, Z.F.9
  • 50
    • 0036850471 scopus 로고    scopus 로고
    • Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles
    • COI: 1:CAS:528:DC%2BD38Xot1Cit78%3D, PID: 12388838
    • Bermudez E, Mangum JB, Asgharian B, Wong BA, Reverdy EE, Janszen DB, Hext PM, Warheit DB, Everitt JI (2002) Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. Toxicol Sci 70(1):86–97. doi:10.1093/toxsci/70.1.86
    • (2002) Toxicol Sci , vol.70 , Issue.1 , pp. 86-97
    • Bermudez, E.1    Mangum, J.B.2    Asgharian, B.3    Wong, B.A.4    Reverdy, E.E.5    Janszen, D.B.6    Hext, P.M.7    Warheit, D.B.8    Everitt, J.I.9
  • 51
    • 0026857603 scopus 로고
    • Pulmonary retention of ultrafine and fine particles in rats
    • COI: 1:CAS:528:DyaK38Xks1Cnt78%3D, PID: 1581076
    • Ferin J, Oberdörster G, Penney DP (1992) Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6(5):535–542. doi:10.1165/ajrcmb/6.5.535
    • (1992) Am J Respir Cell Mol Biol , vol.6 , Issue.5 , pp. 535-542
    • Ferin, J.1    Oberdörster, G.2    Penney, D.P.3
  • 52
    • 0037174958 scopus 로고    scopus 로고
    • Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats
    • Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C (2002) Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxic Environ Health A 65(20):1531–1543. doi:10.1080/00984100290071658
    • (2002) J Toxic Environ Health A , vol.65 , Issue.20 , pp. 1531-1543
    • Oberdörster, G.1    Sharp, Z.2    Atudorei, V.3    Elder, A.4    Gelein, R.5    Lunts, A.6    Kreyling, W.7    Cox, C.8
  • 53
    • 41849120840 scopus 로고    scopus 로고
    • Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats
    • COI: 1:CAS:528:DC%2BD1cXktVegs78%3D, PID: 18000654
    • Fabian E, Landsiedel R, Ma-Hock L, Wiench K, Wohlleben W, van Ravenzwaay B (2008) Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats. Arch Toxicol 82(3):151–157. doi:10.1007/s00204-007-0253-y
    • (2008) Arch Toxicol , vol.82 , Issue.3 , pp. 151-157
    • Fabian, E.1    Landsiedel, R.2    Ma-Hock, L.3    Wiench, K.4    Wohlleben, W.5    van Ravenzwaay, B.6
  • 54
    • 48849108942 scopus 로고    scopus 로고
    • Safety evaluation of titanium dioxide nanoparticles by their absorption and elimination profiles
    • COI: 1:CAS:528:DC%2BD1cXhtVKmtr7N, PID: 18670160
    • Sugibayashi K, Todo H, Kimura E (2008) Safety evaluation of titanium dioxide nanoparticles by their absorption and elimination profiles. J Toxicol Sci 33(3):293–298. doi:10.2131/jts.33.293
    • (2008) J Toxicol Sci , vol.33 , Issue.3 , pp. 293-298
    • Sugibayashi, K.1    Todo, H.2    Kimura, E.3
  • 55
    • 33846131928 scopus 로고    scopus 로고
    • Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration
    • COI: 1:CAS:528:DC%2BD2sXltV2nug%3D%3D, PID: 17197136
    • Wang J, Zhou G, Chen C, Yu H, Wang T, Ma Y, Jia G, Gao Y, Li B, Sun J, Li Y, Jiao F, Zhao Y, Chai Z (2007) Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicol Lett 168(2):176–185. doi:10.1016/j.toxlet.2006.12.001
    • (2007) Toxicol Lett , vol.168 , Issue.2 , pp. 176-185
    • Wang, J.1    Zhou, G.2    Chen, C.3    Yu, H.4    Wang, T.5    Ma, Y.6    Jia, G.7    Gao, Y.8    Li, B.9    Sun, J.10    Li, Y.11    Jiao, F.12    Zhao, Y.13    Chai, Z.14
  • 57
    • 0014002045 scopus 로고
    • High concentration of injected titanium dioxide in abdominal lymph nodes
    • COI: 1:CAS:528:DyaF2sXksFSqsQ%3D%3D, PID: 5925316
    • Huggins CB, Froehlich JP (1966) High concentration of injected titanium dioxide in abdominal lymph nodes. J Exp Med 124(6):1099–1106
    • (1966) J Exp Med , vol.124 , Issue.6 , pp. 1099-1106
    • Huggins, C.B.1    Froehlich, J.P.2
  • 58
    • 0036444327 scopus 로고    scopus 로고
    • Interactions between ultrafine particles and transition metals in vivo and in vitro
    • COI: 1:CAS:528:DC%2BD38XovVyiurc%3D, PID: 12460745
    • Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V (2002) Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 184(3):172–179. doi:10.1006/taap.2002.9501
    • (2002) Toxicol Appl Pharmacol , vol.184 , Issue.3 , pp. 172-179
    • Wilson, M.R.1    Lightbody, J.H.2    Donaldson, K.3    Sales, J.4    Stone, V.5
  • 59
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • COI: 1:CAS:528:DC%2BD2MXntVyls7Y%3D, PID: 16002369
    • Oberdorster G, Oberdorster E, Oberdorster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113(7):823–839. doi:10.2307/3436201
    • (2005) Environ Health Perspect , vol.113 , Issue.7 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 60
    • 65649110160 scopus 로고    scopus 로고
    • In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection
    • COI: 1:CAS:528:DC%2BD1MXls1emsrY%3D, PID: 19156710
    • Chen J, Dong X, Zhao J, Tang G (2009) In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection. J Appl Toxicol 29(4):330–337. doi:10.1002/jat.1414
    • (2009) J Appl Toxicol , vol.29 , Issue.4 , pp. 330-337
    • Chen, J.1    Dong, X.2    Zhao, J.3    Tang, G.4
  • 63
    • 84864136656 scopus 로고    scopus 로고
    • Gene expression in liver injury caused by long-term exposure to titanium dioxide nanoparticles in mice
    • COI: 1:CAS:528:DC%2BC38XhtVShur%2FI, PID: 22539623
    • Cui Y, Liu H, Ze Y, Zengli Z, Hu Y, Cheng Z, Cheng J, Hu R, Gao G, Wang L, Tang M, Hong F (2012) Gene expression in liver injury caused by long-term exposure to titanium dioxide nanoparticles in mice. Toxicol Sci 128(1):171–185. doi:10.1093/toxsci/kfs153
    • (2012) Toxicol Sci , vol.128 , Issue.1 , pp. 171-185
    • Cui, Y.1    Liu, H.2    Ze, Y.3    Zengli, Z.4    Hu, Y.5    Cheng, Z.6    Cheng, J.7    Hu, R.8    Gao, G.9    Wang, L.10    Tang, M.11    Hong, F.12
  • 67
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: bridging inflammation and cardiovascular disease
    • von Hundelshausen P, Weber C (2007) Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ Res 100(1):27–40. doi:10.1161/01.RES.0000252802.25497.b7
    • (2007) Circ Res , vol.100 , Issue.1 , pp. 27-40
    • von Hundelshausen, P.1    Weber, C.2
  • 68
    • 84881343185 scopus 로고    scopus 로고
    • Acute toxicity of intravenously administered titanium dioxide nanoparticles in mice
    • COI: 1:CAS:528:DC%2BC3sXhtlajsLnE, PID: 23950972
    • Xu J, Shi H, Ruth M, Yu H, Lazar L, Zou B, Yang C, Wu A, Zhao J (2013) Acute toxicity of intravenously administered titanium dioxide nanoparticles in mice. PLoS One 8(8):e70618. doi:10.1371/journal.pone.0070618
    • (2013) PLoS One , vol.8 , Issue.8
    • Xu, J.1    Shi, H.2    Ruth, M.3    Yu, H.4    Lazar, L.5    Zou, B.6    Yang, C.7    Wu, A.8    Zhao, J.9
  • 69
    • 72249115549 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice
    • COI: 1:CAS:528:DC%2BD1MXhtl2rtr7E, PID: 19887611
    • Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH (2009) Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res 69(22):8784–8789. doi:10.1158/0008-5472.can-09-2496
    • (2009) Cancer Res , vol.69 , Issue.22 , pp. 8784-8789
    • Trouiller, B.1    Reliene, R.2    Westbrook, A.3    Solaimani, P.4    Schiestl, R.H.5
  • 70
    • 84907027854 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticle-induced oxidative stress triggers DNA damage and hepatic injury in mice
    • COI: 1:CAS:528:DC%2BC2cXhsV2qt7zN, PID: 24367968
    • Shukla RK, Kumar A, Vallabani NVS, Pandey AK, Dhawan A (2014) Titanium dioxide nanoparticle-induced oxidative stress triggers DNA damage and hepatic injury in mice. Nanomedicine 9(9):1423–1434
    • (2014) Nanomedicine , vol.9 , Issue.9 , pp. 1423-1434
    • Shukla, R.K.1    Kumar, A.2    Vallabani, N.V.S.3    Pandey, A.K.4    Dhawan, A.5
  • 71
    • 0028453635 scopus 로고
    • Programmed cell death: necrosis versus apoptosis
    • COI: 1:STN:280:DyaK2M%2Fitlyltg%3D%3D, PID: 7937727
    • Farber E (1994) Programmed cell death: necrosis versus apoptosis. Mod Pathol 7(5):605–609
    • (1994) Mod Pathol , vol.7 , Issue.5 , pp. 605-609
    • Farber, E.1
  • 72
    • 80755125324 scopus 로고    scopus 로고
    • Physiological and histological impact of Azadirachta indica (neem) leaves extract in a rat model of cisplatin-induced hepato and nephrotoxicity
    • COI: 1:CAS:528:DC%2BC3MXhs1eqtrvK
    • Ezz-Din D, Gabry MS, Farrag ARH, Moneim AEA (2011) Physiological and histological impact of Azadirachta indica (neem) leaves extract in a rat model of cisplatin-induced hepato and nephrotoxicity. J Med Plants Res 5(23):5499–5506
    • (2011) J Med Plants Res , vol.5 , Issue.23 , pp. 5499-5506
    • Ezz-Din, D.1    Gabry, M.S.2    Farrag, A.R.H.3    Moneim, A.E.A.4
  • 73
    • 78149422525 scopus 로고    scopus 로고
    • The mechanism of oxidative damage in the nephrotoxicity of mice caused by nano-anatase TiO2
    • COI: 1:CAS:528:DC%2BC3cXhtl2isLfP
    • Zhao J, Li N, Wang S, Zhao X, Wang J, Yan J, Ruan J, Wang H, Hong F (2010) The mechanism of oxidative damage in the nephrotoxicity of mice caused by nano-anatase TiO2. J Exp Nanosci 5(5):447–462. doi:10.1080/17458081003628931
    • (2010) J Exp Nanosci , vol.5 , Issue.5 , pp. 447-462
    • Zhao, J.1    Li, N.2    Wang, S.3    Zhao, X.4    Wang, J.5    Yan, J.6    Ruan, J.7    Wang, H.8    Hong, F.9
  • 74
    • 67651163427 scopus 로고    scopus 로고
    • TiO2 nanoparticles translocation and potential toxicological effect in rats after intraarticular injection
    • COI: 1:CAS:528:DC%2BD1MXpt1Cju78%3D, PID: 19500841
    • Wang J-X, Fan Y-B, Gao Y, Hu Q-H, Wang T-C (2009) TiO2 nanoparticles translocation and potential toxicological effect in rats after intraarticular injection. Biomaterials 30(27):4590–4600. doi:10.1016/j.biomaterials.2009.05.008
    • (2009) Biomaterials , vol.30 , Issue.27 , pp. 4590-4600
    • Wang, J.-X.1    Fan, Y.-B.2    Gao, Y.3    Hu, Q.-H.4    Wang, T.-C.5
  • 75
    • 84875352123 scopus 로고    scopus 로고
    • Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications
    • COI: 1:CAS:528:DC%2BC3sXns1Ors7k%3D, PID: 23406204
    • Gui S, Sang X, Zheng L, Ze Y, Zhao X, Sheng L, Sun Q, Cheng Z, Cheng J, Hu R, Wang L, Hong F, Tang M (2013) Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications. Part Fibre Toxicol 10(1):4
    • (2013) Part Fibre Toxicol , vol.10 , Issue.1 , pp. 4
    • Gui, S.1    Sang, X.2    Zheng, L.3    Ze, Y.4    Zhao, X.5    Sheng, L.6    Sun, Q.7    Cheng, Z.8    Cheng, J.9    Hu, R.10    Wang, L.11    Hong, F.12    Tang, M.13
  • 76
    • 14944360395 scopus 로고    scopus 로고
    • Inflammatory response, reactive oxygen species, programmed (necrotic-like and apoptotic) cell death and cancer
    • COI: 1:CAS:528:DC%2BD2MXks1GjsA%3D%3D
    • Johar D, Roth JC, Bay GH, Walker JN, Kroczak TJ, Los M (2004) Inflammatory response, reactive oxygen species, programmed (necrotic-like and apoptotic) cell death and cancer. Annal Med Univ Bialystok 49:31–39
    • (2004) Annal Med Univ Bialystok , vol.49 , pp. 31-39
    • Johar, D.1    Roth, J.C.2    Bay, G.H.3    Walker, J.N.4    Kroczak, T.J.5    Los, M.6
  • 77
    • 0027715774 scopus 로고
    • Binucleation and polyploidization patterns in developmental and regenerative rat liver growth
    • COI: 1:STN:280:DyaK2s3ktVCktg%3D%3D, PID: 9116122
    • Gerlyng P, Åbyholm A, Grotmol T, Erikstein B, Huitfeldt H, Stokke T, Seglen P (1993) Binucleation and polyploidization patterns in developmental and regenerative rat liver growth. Cell Prolif 26(6):557–565
    • (1993) Cell Prolif , vol.26 , Issue.6 , pp. 557-565
    • Gerlyng, P.1    Åbyholm, A.2    Grotmol, T.3    Erikstein, B.4    Huitfeldt, H.5    Stokke, T.6    Seglen, P.7
  • 78
    • 13444310792 scopus 로고    scopus 로고
    • Swelling of hepatocytes injured by oxidative stress suggests pathological changes related to macromolecular crowding
    • PID: 15694703
    • Del Monte U (2005) Swelling of hepatocytes injured by oxidative stress suggests pathological changes related to macromolecular crowding. Med Hypotheses 64(4):818–825. doi:10.1016/j.mehy.2004.08.028
    • (2005) Med Hypotheses , vol.64 , Issue.4 , pp. 818-825
    • Del Monte, U.1
  • 79
    • 78449296021 scopus 로고    scopus 로고
    • Metal-based nanoparticles and their toxicity assessment. Wiley Interdisciplinary Reviews
    • COI: 1:CAS:528:DC%2BC3cXhtFOnsrbJ
    • Schrand AM, Rahman MF, Hussain SM, Schlager JJ, Smith DA, Syed AF (2010) Metal-based nanoparticles and their toxicity assessment. Wiley Interdisciplinary Reviews. Nanomed Nanobiotechnol 2(5):544–568
    • (2010) Nanomed Nanobiotechnol , vol.2 , Issue.5 , pp. 544-568
    • Schrand, A.M.1    Rahman, M.F.2    Hussain, S.M.3    Schlager, J.J.4    Smith, D.A.5    Syed, A.F.6
  • 80
    • 49749131612 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells
    • COI: 1:CAS:528:DC%2BD1cXhtVejtrzE, PID: 18662754
    • Park EJ, Yi J, Chung KH, Ryu DY, Choi J, Park K (2008) Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol Lett 180(3):222–229. doi:10.1016/j.toxlet.2008.06.869
    • (2008) Toxicol Lett , vol.180 , Issue.3 , pp. 222-229
    • Park, E.J.1    Yi, J.2    Chung, K.H.3    Ryu, D.Y.4    Choi, J.5    Park, K.6
  • 81
    • 77951937998 scopus 로고    scopus 로고
    • Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics
    • PID: 20017923
    • Johnston HJ, Hutchison GR, Christensen FM, Peters S, Hankin S, Stone V (2009) Identification of the mechanisms that drive the toxicity of TiO2 particulates: the contribution of physicochemical characteristics. Part Fibre Toxicol 6:33–59
    • (2009) Part Fibre Toxicol , vol.6 , pp. 33-59
    • Johnston, H.J.1    Hutchison, G.R.2    Christensen, F.M.3    Peters, S.4    Hankin, S.5    Stone, V.6
  • 82
    • 34548648936 scopus 로고    scopus 로고
    • Liver function tests and their interpretation
    • COI: 1:STN:280:DC%2BD2svot1Cltg%3D%3D, PID: 17699976
    • Thapa BR, Walia A (2007) Liver function tests and their interpretation. Indian J Pediatr 74(7):663–671
    • (2007) Indian J Pediatr , vol.74 , Issue.7 , pp. 663-671
    • Thapa, B.R.1    Walia, A.2
  • 84
    • 13444284018 scopus 로고    scopus 로고
    • New technologies and screening strategies for hepatotoxicity: use of in vitro models
    • COI: 1:CAS:528:DC%2BD2MXhtFaqu7o%3D, PID: 15805052
    • Dambach DM, Andrews BA, Moulin F (2005) New technologies and screening strategies for hepatotoxicity: use of in vitro models. Toxicol Pathol 33(1):17–26. doi:10.1080/01926230590522284
    • (2005) Toxicol Pathol , vol.33 , Issue.1 , pp. 17-26
    • Dambach, D.M.1    Andrews, B.A.2    Moulin, F.3
  • 85
    • 0014240285 scopus 로고
    • Cholestasis
    • COI: 1:STN:280:DyaF1c3nvFWnsg%3D%3D, PID: 4871695
    • Popper HANS (1968) Cholestasis. Annu Rev Med 19(1):39–56
    • (1968) Annu Rev Med , vol.19 , Issue.1 , pp. 39-56
    • Popper, H.A.N.S.1
  • 87
    • 39649115201 scopus 로고    scopus 로고
    • Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
    • PID: 18242692
    • De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJAM, Geertsma RE (2008) Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29(12):1912–1919. doi:10.1016/j.biomaterials.2007.12.037
    • (2008) Biomaterials , vol.29 , Issue.12 , pp. 1912-1919
    • De Jong, W.H.1    Hagens, W.I.2    Krystek, P.3    Burger, M.C.4    Sips, A.J.A.M.5    Geertsma, R.E.6
  • 88
    • 42549152143 scopus 로고    scopus 로고
    • Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats
    • COI: 1:CAS:528:DC%2BD1cXhtVyitbg%3D, PID: 18217714
    • Jain TK, Reddy MK, Morales MA, Leslie-Pelecky DL, Labhasetwar V (2008) Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol Pharm 5(2):316–327. doi:10.1021/mp7001285
    • (2008) Mol Pharm , vol.5 , Issue.2 , pp. 316-327
    • Jain, T.K.1    Reddy, M.K.2    Morales, M.A.3    Leslie-Pelecky, D.L.4    Labhasetwar, V.5
  • 89
    • 61649102498 scopus 로고    scopus 로고
    • Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine
    • COI: 1:CAS:528:DC%2BD1cXhsFals7vK, PID: 19099455
    • Burns AA, Vider J, Ow H, Herz E, Penate-Medina O, Baumgart M, Larson SM, Wiesner U, Bradbury M (2009) Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine. Nano Lett 9(1):442–448. doi:10.1021/nl803405h
    • (2009) Nano Lett , vol.9 , Issue.1 , pp. 442-448
    • Burns, A.A.1    Vider, J.2    Ow, H.3    Herz, E.4    Penate-Medina, O.5    Baumgart, M.6    Larson, S.M.7    Wiesner, U.8    Bradbury, M.9
  • 90
    • 67349194080 scopus 로고    scopus 로고
    • Pulmonary toxicity induced by three forms of titanium dioxide nanoparticles via intra-tracheal instillation in rats
    • COI: 1:CAS:528:DC%2BD1MXotFOhs7Y%3D
    • Liu R, Yin L, Pu Y, Liang G, Zhang J, Su Y, Xiao Z, Ye B (2009) Pulmonary toxicity induced by three forms of titanium dioxide nanoparticles via intra-tracheal instillation in rats. Prog Nat Sci 19(5):573–579. doi:10.1016/j.pnsc.2008.06.020
    • (2009) Prog Nat Sci , vol.19 , Issue.5 , pp. 573-579
    • Liu, R.1    Yin, L.2    Pu, Y.3    Liang, G.4    Zhang, J.5    Su, Y.6    Xiao, Z.7    Ye, B.8
  • 91
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • COI: 1:CAS:528:DC%2BD28XptVyrsg%3D%3D, PID: 16456071
    • Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622–627. doi:10.1126/science.1114397
    • (2006) Science , vol.311 , Issue.5761 , pp. 622-627
    • Nel, A.1    Xia, T.2    Mädler, L.3    Li, N.4
  • 92
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: oxidants and antioxidants
    • COI: 1:CAS:528:DyaK2sXivFemtLc%3D, PID: 9129943
    • Sies H (1997) Oxidative stress: oxidants and antioxidants. Exp Physiol 82(2):291–295. doi:10.1113/expphysiol.1997.sp004024
    • (1997) Exp Physiol , vol.82 , Issue.2 , pp. 291-295
    • Sies, H.1
  • 93
    • 84930212923 scopus 로고    scopus 로고
    • Fluorescence lifetime imaging of endogenous biomarker of oxidative stress
    • Datta R, Alfonso-García A, Cinco R, Gratton E (2015) Fluorescence lifetime imaging of endogenous biomarker of oxidative stress. Sci Rep 5:1–10
    • (2015) Sci Rep , vol.5 , pp. 1-10
    • Datta, R.1    Alfonso-García, A.2    Cinco, R.3    Gratton, E.4
  • 94
    • 0029888496 scopus 로고    scopus 로고
    • Oxidative stress in neurodegenerative diseases
    • COI: 1:CAS:528:DyaK28Xis1ertLk%3D, PID: 8725383
    • Simonian NA, Coyle JT (1996) Oxidative stress in neurodegenerative diseases. Annu Rev Pharmacol Toxicol 36(1):83–106. doi:10.1146/annurev.pa.36.040196.000503
    • (1996) Annu Rev Pharmacol Toxicol , vol.36 , Issue.1 , pp. 83-106
    • Simonian, N.A.1    Coyle, J.T.2
  • 95
    • 84907009518 scopus 로고    scopus 로고
    • Dose-dependent effect of deltamethrin in testis, liver, and kidney of Wistar rats
    • PID: 25253921
    • Sharma P, Singh R, Jan M (2014) Dose-dependent effect of deltamethrin in testis, liver, and kidney of Wistar rats. Toxicol Int 21(2):131–139. doi:10.4103/0971-6580.139789
    • (2014) Toxicol Int , vol.21 , Issue.2 , pp. 131-139
    • Sharma, P.1    Singh, R.2    Jan, M.3
  • 96
    • 0000018933 scopus 로고
    • Pesticides derived from plants and other organisms
    • Ray DE (1991) Pesticides derived from plants and other organisms. Handb Pestic Toxicol 2(13):585–636
    • (1991) Handb Pestic Toxicol , vol.2 , Issue.13 , pp. 585-636
    • Ray, D.E.1
  • 97
    • 0032948625 scopus 로고    scopus 로고
    • Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species
    • COI: 1:CAS:528:DyaK1MXjsVWqur8%3D, PID: 10355540
    • Kale M, Rathore N, John S, Bhatnagar D (1999) Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxicol Lett 105(3):197–205. doi:10.1016/S0378-4274(98)00399-3
    • (1999) Toxicol Lett , vol.105 , Issue.3 , pp. 197-205
    • Kale, M.1    Rathore, N.2    John, S.3    Bhatnagar, D.4
  • 98
    • 0036454001 scopus 로고    scopus 로고
    • Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor
    • COI: 1:CAS:528:DC%2BD38XovFOqtrs%3D, PID: 12451445
    • Latchoumycandane C, Mathur P (2002) Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor. Arch Toxicol 76(12):692–698. doi:10.1007/s00204-002-0388-9
    • (2002) Arch Toxicol , vol.76 , Issue.12 , pp. 692-698
    • Latchoumycandane, C.1    Mathur, P.2
  • 99
    • 70350593880 scopus 로고    scopus 로고
    • 2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure
    • COI: 1:CAS:528:DC%2BD1MXhtlyru7rM, PID: 19501137
    • 2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicol Lett 191(1):1–8. doi:10.1016/j.toxlet.2009.05.020
    • (2009) Toxicol Lett , vol.191 , Issue.1 , pp. 1-8
    • Wu, J.1    Liu, W.2    Xue, C.3    Zhou, S.4    Lan, F.5    Bi, L.6    Xu, H.7    Yang, X.8    Zeng, F.-D.9
  • 100
    • 79952112961 scopus 로고    scopus 로고
    • Systematic influence induced by 3 nm titanium dioxide following intratracheal instillation of mice
    • COI: 1:CAS:528:DC%2BC3cXhtlyqsbvJ, PID: 21121364
    • Li Y, Li J, Yin J, Li W, Kang C, Huang Q, Li Q (2010) Systematic influence induced by 3 nm titanium dioxide following intratracheal instillation of mice. J Nanosci Nanotechnol 10(12):8544–8549
    • (2010) J Nanosci Nanotechnol , vol.10 , Issue.12 , pp. 8544-8549
    • Li, Y.1    Li, J.2    Yin, J.3    Li, W.4    Kang, C.5    Huang, Q.6    Li, Q.7
  • 102
    • 84876164362 scopus 로고    scopus 로고
    • 2) in male albino rats with special reference to its effect on reproductive system
    • 2) in male albino rats with special reference to its effect on reproductive system. J Am Sci 6(11):865–872
    • (2010) J Am Sci , vol.6 , Issue.11 , pp. 865-872
    • El-Sharkawy, N.I.1    Hamza, S.M.2    Abou-Zeid, E.H.3
  • 103
    • 77956446944 scopus 로고    scopus 로고
    • Hepatocyte apoptosis and its molecular mechanisms in mice caused by titanium dioxide nanoparticles
    • COI: 1:CAS:528:DC%2BC3cXhtFCht77L, PID: 20724067
    • Cui Y, Gong X, Duan Y, Li N, Hu R, Liu H, Hong M, Zhou M, Wang L, Wang H, Hong F (2010) Hepatocyte apoptosis and its molecular mechanisms in mice caused by titanium dioxide nanoparticles. J Hazard Mater 183(1–3):874–880. doi:10.1016/j.jhazmat.2010.07.109
    • (2010) J Hazard Mater , vol.183 , Issue.1-3 , pp. 874-880
    • Cui, Y.1    Gong, X.2    Duan, Y.3    Li, N.4    Hu, R.5    Liu, H.6    Hong, M.7    Zhou, M.8    Wang, L.9    Wang, H.10    Hong, F.11
  • 104
    • 71549145597 scopus 로고    scopus 로고
    • Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse
    • COI: 1:CAS:528:DC%2BD1MXhsFGhtbbF, PID: 19892005
    • Shin JA, Lee EJ, Seo SM, Kim HS, Kang JL, Park EM (2010) Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse. Neuroscience 165(2):445–454. doi:10.1016/j.neuroscience.2009.10.057
    • (2010) Neuroscience , vol.165 , Issue.2 , pp. 445-454
    • Shin, J.A.1    Lee, E.J.2    Seo, S.M.3    Kim, H.S.4    Kang, J.L.5    Park, E.M.6
  • 106
    • 56049102066 scopus 로고    scopus 로고
    • Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles
    • COI: 1:CAS:528:DC%2BD1cXhsVWmt7fF, PID: 18929619
    • Wang J, Liu Y, Jiao F, Lao F, Li W, Gu Y, Li Y, Ge C, Zhou G, Li B, Zhao Y, Chai Z, Chen C (2008) Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology 254(1–2):82–90. doi:10.1016/j.tox.2008.09.014
    • (2008) Toxicology , vol.254 , Issue.1-2 , pp. 82-90
    • Wang, J.1    Liu, Y.2    Jiao, F.3    Lao, F.4    Li, W.5    Gu, Y.6    Li, Y.7    Ge, C.8    Zhou, G.9    Li, B.10    Zhao, Y.11    Chai, Z.12    Chen, C.13
  • 107
    • 80054755652 scopus 로고    scopus 로고
    • Effects of cadmium chloride and sodium selenite alone or in combination on the liver of male Sprague–Dawley rats assessed by different assays
    • COI: 1:CAS:528:DC%2BC3MXht1OisbbP, PID: 21213067
    • Jabeen F, Chaudhry AS (2011) Effects of cadmium chloride and sodium selenite alone or in combination on the liver of male Sprague–Dawley rats assessed by different assays. Biol Trace Elem Res 143(2):1077–1090
    • (2011) Biol Trace Elem Res , vol.143 , Issue.2 , pp. 1077-1090
    • Jabeen, F.1    Chaudhry, A.S.2
  • 108
    • 84957413537 scopus 로고    scopus 로고
    • Studies on the oxidative stress and gill histopathology in Channa punctatus of the canal receiving heavy metal-loaded effluent of Kasimpur thermal power plant
    • COI: 1:CAS:528:DC%2BC2cXitFaitrfN
    • Javed M, Usmani N, Ahmad I, Ahmad M (2015) Studies on the oxidative stress and gill histopathology in Channa punctatus of the canal receiving heavy metal-loaded effluent of Kasimpur thermal power plant. Environ Monit Assess 187(1):1–11
    • (2015) Environ Monit Assess , vol.187 , Issue.1 , pp. 1-11
    • Javed, M.1    Usmani, N.2    Ahmad, I.3    Ahmad, M.4
  • 109
    • 80051472747 scopus 로고    scopus 로고
    • In vivo comparative biokinetics and biocompatibility of titanium and zirconium microparticles
    • COI: 1:CAS:528:DC%2BC3MXpvVWku7o%3D
    • Olmedo DG, Tasat DR, Evelson P, Rebagliatti R, Guglielmotti MB, Cabrini RL (2011) In vivo comparative biokinetics and biocompatibility of titanium and zirconium microparticles. J Biomed Mater Res Part A 98A(4):604–613. doi:10.1002/jbm.a.33145
    • (2011) J Biomed Mater Res Part A , vol.98A , Issue.4 , pp. 604-613
    • Olmedo, D.G.1    Tasat, D.R.2    Evelson, P.3    Rebagliatti, R.4    Guglielmotti, M.B.5    Cabrini, R.L.6
  • 110
    • 84986602529 scopus 로고    scopus 로고
    • Comparative study of the biological efficacy of titanium dioxide nano-and microparticles
    • Grigoryeva V, Zayeva O, Krivova N (2015) Comparative study of the biological efficacy of titanium dioxide nano-and microparticles. Adv Mater Res Trans Tech Publ 1085:357–362
    • (2015) Adv Mater Res Trans Tech Publ , vol.1085 , pp. 357-362
    • Grigoryeva, V.1    Zayeva, O.2    Krivova, N.3
  • 111
    • 79951813476 scopus 로고    scopus 로고
    • 2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damage
    • COI: 1:CAS:528:DC%2BC3MXisFWrs74%3D, PID: 21296382
    • 2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damage. Sci Total Environ 409(8):1444–1452. doi:10.1016/j.scitotenv.2011.01.015
    • (2011) Sci Total Environ , vol.409 , Issue.8 , pp. 1444-1452
    • Xiong, D.1    Fang, T.2    Yu, L.3    Sima, X.4    Zhu, W.5
  • 113
    • 40749098186 scopus 로고    scopus 로고
    • Comparison of the biological activity between ultrafine and fine titanium dioxide particles in RAW 264.7 cells associated with oxidative stress
    • COI: 1:CAS:528:DC%2BD1cXjtFSisL0%3D
    • Kang JL, Moon C, Lee HS, Lee HW, Park EM, Kim HS, Castranova V (2008) Comparison of the biological activity between ultrafine and fine titanium dioxide particles in RAW 264.7 cells associated with oxidative stress. J Toxic Environ Health A 71(8):478–485
    • (2008) J Toxic Environ Health A , vol.71 , Issue.8 , pp. 478-485
    • Kang, J.L.1    Moon, C.2    Lee, H.S.3    Lee, H.W.4    Park, E.M.5    Kim, H.S.6    Castranova, V.7
  • 115
    • 0037235805 scopus 로고    scopus 로고
    • The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types
    • COI: 1:CAS:528:DC%2BD38XpslGlsL4%3D, PID: 12476359
    • Dick CAJ, Brown DM, Donaldson K, Stone V (2003) The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal Toxicol 15(1):39–52. doi:10.1080/08958370304454
    • (2003) Inhal Toxicol , vol.15 , Issue.1 , pp. 39-52
    • Dick, C.A.J.1    Brown, D.M.2    Donaldson, K.3    Stone, V.4
  • 117
    • 84986579945 scopus 로고    scopus 로고
    • Opinion on titanium dioxide (nano form)
    • SCCS (2013) Opinion on titanium dioxide (nano form). Sci Committee Consumer Safety, 22 July 2013
    • (2013) Sci Committee Consumer Safety, 22 July , pp. 2013


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