Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles

Journal of Hazardous Materials

Volumn 191, Issue 1-3, 2011, Pages 32-40

  Hu, Renping ^a   Zheng, Lei ^a   Zhang, Ting ^b,c   Gao, Guodong ^a   Cui, Yaling ^a   Cheng, Zhe ^a   Cheng, Jie ^a   Hong, Mengmeng ^a   Tang, Meng ^b,c   Hong, Fashui ^a  

^a SOOCHOW UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

^c Southeast University   (China)

Author keywords

Apoptotic pathway; Hippocampus; Mice; Titanium dioxide nanoparticles

Indexed keywords

APOPTOSIS; APOPTOTIC PATHWAYS; CASPASE-3; CENTRAL NERVOUS SYSTEMS; HIPPOCAMPUS; INTRAGASTRIC ADMINISTRATION; MICE; MOLECULAR MECHANISM; NANO-MATERIALS; REACTIVE OXYGEN SPECIES; RECOGNITION MEMORY; TIO; TITANIUM DIOXIDE NANOPARTICLES;

BRAIN; CELL DEATH; DRUG PRODUCTS; NANOPARTICLES; OXIDES; TITANIUM;

TITANIUM DIOXIDE;

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; NANOPARTICLE; PEROXIDASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TITANIUM DIOXIDE;

APOPTOSIS; CHEMICAL POLLUTANT; DOSE-RESPONSE RELATIONSHIP; MOLECULAR ANALYSIS; NERVOUS SYSTEM; POLLUTION EFFECT; POLLUTION EXPOSURE; RODENT; SPATIAL VARIATION; TITANIUM; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA STRUCTURE; FEMALE; HIPPOCAMPUS; LIPID PEROXIDATION; MEMORY DISORDER; MOLECULAR MECHANICS; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; RECOGNITION; SPATIAL MEMORY; X RAY DIFFRACTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BASE SEQUENCE; CASPASES; DNA PRIMERS; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; METAL NANOPARTICLES; MICE; MICE, INBRED ICR; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; TITANIUM;

MUS;

EID: 79957680045     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2011.04.027     Document Type: Article

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