Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells

Particle and Fibre Toxicology

Volumn 9, Issue , 2012, Pages

  Fisichella, Matthieu ^a   Berenguer, Frederic ^a   Steinmetz, Gerard ^a   Auffan, Melanie ^b,c   Rose, Jerome ^b,c   Prat, Odette ^a,c  

^a DIF   (France)

^b CEREGE   (France)

^c International Consortium for the Environmental Implications of Nanotechnology (iCEINT)   (France)

Author keywords

degradation of nanomaterials; Gene expression; Life cycle; Nanoparticles (NPs); Surface treated nanoparticles (STNPs); Titanium dioxide; Toxicity

Indexed keywords

NANOPARTICLE; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE SURFACE TREATED NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; CELL FUNCTION; CELL STRAIN CACO 2; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GASTROINTESTINAL TOXICITY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; INTERNALIZATION; INTESTINE EPITHELIUM CELL; MICROARRAY ANALYSIS; NANOANALYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TOXICITY TESTING; TOXICOGENETICS; TRANSMISSION ELECTRON MICROSCOPY;

CACO-2 CELLS; COATED MATERIALS, BIOCOMPATIBLE; ENTEROCYTES; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; METAL NANOPARTICLES; MICROSCOPY, ELECTRON; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; SURFACE PROPERTIES; TITANIUM; TOXICOGENETICS;

EID: 84865638405     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-9-18     Document Type: Article

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