Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways

Nanotoxicology

Volumn 6, Issue 7, 2012, Pages 724-735

  Knuckles, Travis L ^a   Yi, Jinghai ^a   Frazer, David G ^a,b   Leonard, Howard D ^b   Chen, Bean T ^b   Castranova, Vince ^b   Nurkiewicz, Timothy R ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Microvascular; Nitric oxide; Sympathetic nervous system; Titanium dioxide; Whole body inhalation

Indexed keywords

ADRENERGIC RECEPTOR; ILOPROST; NANOPARTICLE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; TITANIUM DIOXIDE;

AEROSOL; ANIMAL EXPERIMENT; ARTERIOLAR VASOREACTIVITY; ARTERY CONSTRICTION; ARTICLE; BIOAVAILABILITY; BLOOD VESSEL PARAMETERS; CONTROLLED STUDY; ENZYME INHIBITION; HYPEREMIA; MALE; MICROSCOPY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; TRAPEZIUS MUSCLE; VASODILATATION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADMINISTRATION, INHALATION; ANIMALS; ARTERIOLES; CYCLOOXYGENASE INHIBITORS; HYPEREMIA; MALE; NANOPARTICLES; NITRIC OXIDE; PARTICLE SIZE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM; TITANIUM; VASOCONSTRICTION; VASODILATION;

EID: 84867502940     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.606926     Document Type: Article

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