Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice

Journal of Biomedical Materials Research - Part A

Volumn 104, Issue 6, 2016, Pages 1452-1461

  Hong, F ^a   Wu, N ^a   Ge, Y ^a   Zhou, Y ^a   Shen, T ^a   Qiang, Q ^a   Zhang, Q ^a   Chen, M ^a   Wang, Y ^a   Wang, L ^b   Hong, J ^c  

^a HUAIYIN NORMAL UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

mice; renal fibration; renal inflammation; TGF Smads p38MAPK pathway; titanium dioxide nanoparticles

Indexed keywords

CHEMICAL ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MAMMALS; NANOPARTICLES; OXIDES; PATHOLOGY; PROTEINS; TITANIUM;

MICE; N-ACETYLGLUCOSAMINIDASE; NANO-SIZED TITANIUM DIOXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASE; RENAL FIBRATION; RENAL INFLAMMATION; TITANIUM DIOXIDE NANOPARTICLES; TRANSFORMING GROWTH FACTORS;

TITANIUM DIOXIDE;

ACETYLGLUCOSAMINIDASE; ALPHA SMOOTH MUSCLE ACTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TITANIUM DIOXIDE NANOPARTICLE; TRANSFORMING GROWTH FACTOR BETA1; BIOLOGICAL MARKER; MESSENGER RNA; NANOPARTICLE; SMAD PROTEIN; TITANIUM; TITANIUM DIOXIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BODY WEIGHT; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; EXTRACELLULAR MATRIX; KIDNEY FUNCTION; MALE; MOUSE; NEPHRITIS; NONHUMAN; PARTICLE SIZE; PROTEIN EXPRESSION; PROTEIN FOLDING; ANIMAL; BLOOD; CHEMISTRY; DRINKING BEHAVIOR; DRUG EFFECTS; FEEDING BEHAVIOR; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; URINE;

ANIMALS; BIOMARKERS; DRINKING BEHAVIOR; FEEDING BEHAVIOR; FIBROSIS; GENE EXPRESSION REGULATION; INFLAMMATION; KIDNEY; MALE; MICE, INBRED ICR; NANOPARTICLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PARTICLE SIZE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TITANIUM; TRANSFORMING GROWTH FACTOR BETA;

EID: 84976232065     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35678     Document Type: Article

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