Titanium dioxide nanoparticle-induced testicular damage, spermatogenesis suppression, and gene expression alterations in male mice

Journal of Hazardous Materials

Volumn 258-259, Issue , 2013, Pages 133-143

  Gao, Guodong ^a   Ze, Yuguan ^a   Zhao, Xiaoyang ^a   Sang, Xuezi ^a   Zheng, Lei ^a   Ze, Xiao ^a   Gui, Suxin ^a   Sheng, Lei ^a   Sun, Qingqing ^a   Hong, Jie ^a   Yu, Xiaohong ^a   Wang, Ling ^a   Hong, Fashui ^a,b,c   Zhang, Xueguang ^b,c  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c Technology and Jiangsu Province   (China)

Author keywords

Gene expression profile; Sex hormones; Sperm lesion; Testis damage; Titanium dioxide nanoparticles

Indexed keywords

GENE EXPRESSION PROFILES; SEX HORMONES; SPERM LESION; TESTIS DAMAGE; TITANIUM DIOXIDE NANOPARTICLES;

GENE EXPRESSION; MAMMALS; NANOPARTICLES; OXIDES; STEROID HORMONES; TOXICITY;

TITANIUM DIOXIDE;

ADAM3 PROTEIN; CYTOCHROME P450 2E1; LEPTIN; LY6E PROTEIN; MVD PROTEIN; NANOPARTICLE; PRM1 PROTEIN; PSMC3IP PROTEIN; REGULATOR PROTEIN; SC4MOL PROTEIN; SEX HORMONE; SPATA19 PROTEIN; STEROID 5ALPHA REDUCTASE 2; TDRD6 PROTEIN; TITANIUM DIOXIDE; TNP2 PROTEIN; UNCLASSIFIED DRUG;

ANATASE; GENE EXPRESSION; MALE; REPRODUCTIVE BEHAVIOR; RODENT; SEX HORMONE; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD TESTIS BARRIER; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HORMONE BLOOD LEVEL; HORMONE METABOLISM; MALE; MICROARRAY ANALYSIS; MOUSE; NANOTOXICOLOGY; NONHUMAN; REGULATOR GENE; SEMEN ABNORMALITY; SPERMATOGENESIS; SPERMATOZOON MOTILITY; STEROID METABOLISM; TESTIS FUNCTION; TESTIS INJURY; UPREGULATION;

ANIMALS; CELL COUNT; GENE EXPRESSION; GENE EXPRESSION PROFILING; MALE; METAL NANOPARTICLES; MICE; PROTEIN ARRAY ANALYSIS; REACTIVE OXYGEN SPECIES; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA; TESTIS; TITANIUM;

EID: 84878248114     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2013.04.046     Document Type: Article

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