Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice

Journal of Applied Toxicology

Volumn 35, Issue 10, 2015, Pages 1122-1132

  Hu, Hailong ^a   Guo, Qian ^a   Wang, Changlin ^a   Ma, Xiao ^b   He, Hongjuan ^a   Oh, Yuri ^c   Feng, Yujie ^a   Wu, Qiong ^a   Gu, Ning ^a  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b YUNNAN AGRICULTURAL UNIVERSITY   (China)

^c WAKAYAMA UNIVERSITY   (Japan)

Author keywords

Insulin; IR; Plasma glucose; ROS; TiO2 nanoparticles

Indexed keywords

FATTY ACID; GLUCOSE; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TITANIUM DIOXIDE NANOPARTICLE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; GLUCOSE BLOOD LEVEL; LIPID; METAL NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOCRINE SYSTEM; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; KIDNEY; LIGHT SCATTERING; LIVER; MOUSE; NONHUMAN; PANCREAS; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCANNING ELECTRON MICROSCOPY; SMALL INTESTINE; SPLEEN; TRANSMISSION ELECTRON MICROSCOPY; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; APOPTOSIS; BLOOD; DRUG EFFECTS; EATING; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PHOSPHORYLATION; TISSUE DISTRIBUTION;

MUS;

ADMINISTRATION, ORAL; ANIMALS; APOPTOSIS; BLOOD GLUCOSE; BODY WEIGHT; CYTOKINES; EATING; INSULIN RESISTANCE; LIPIDS; LIVER; MALE; METAL NANOPARTICLES; MICE; MICE, INBRED ICR; PARTICLE SIZE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; TISSUE DISTRIBUTION; TITANIUM;

EID: 84939271702     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3150     Document Type: Article

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