Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutinin-stimulated human lymphocytes

Biochemical and Biophysical Research Communications

Volumn 386, Issue 4, 2009, Pages 682-687

  Kang, Su Jin ^a,b   Kim, Byeong Mo ^a,c   Lee, Young Joon ^b   Hong, Sung Hee ^c   Chung, Hai Won ^a  

^a Seoul National University   (South Korea)

^b Daegu Haany University   (South Korea)

^c Korea Institute of Radiation and Medical Science   (South Korea)

Author keywords

Apoptosis; Caspase 8; Inhibitors; Mitogen activated protein kinases; RNA interference; Titanium dioxide nanoparticles

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 8; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; NANOPARTICLE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHYTOHEMAGGLUTININ; PROTEIN BID; STRESS ACTIVATED PROTEIN KINASE; TITANIUM DIOXIDE;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 8; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MAP KINASE KINASE 4; NANOPARTICLES; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHYTOHEMAGGLUTININS; TITANIUM;

EID: 67650457630     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.097     Document Type: Article

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