Oxidative damage of lung and its protective mechanism in mice caused by long-term exposure to titanium dioxide nanoparticles

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 10, 2012, Pages 2554-2562

  Sun, Qingqing ^a   Tan, Danlin ^a   Zhou, Qiuping ^a   Liu, Xiaorun ^b,c   Cheng, Zhe ^a   Liu, Gan ^a   Zhu, Min ^a   Sang, Xuezi ^a   Gui, Suxin ^a   Cheng, Jie ^a   Hu, Renping ^a   Tang, Meng ^b,c   Hong, Fashui ^a  

^a SOOCHOW UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

^c Southeast University   (China)

Author keywords

inflammation; lung; nuclear factor erythroid 2 related factor 2; oxidative stress; titanium dioxide nanoparticles

Indexed keywords

BODY WEIGHT; CATALYTIC SUBUNITS; EXPRESSION LEVELS; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; INFLAMMATION; INFLAMMATORY RESPONSE; INTRATRACHEAL; LONG TERM EXPOSURE; LUNG; MOLECULAR TARGETS; MOUSE LUNG; NUCLEAR FACTORS; OXIDATIVE DAMAGE; PULMONARY EDEMA; REACTIVE OXYGEN SPECIES; SIGNAL PATHWAYS; TIO; TITANIUM DIOXIDE NANOPARTICLES;

AMINO ACIDS; BIOLOGICAL ORGANS; CELL DEATH; MAMMALS; NANOPARTICLES; OXIDATIVE STRESS; OXIDES; PORPHYRINS;

TITANIUM DIOXIDE;

GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE; TRANSCRIPTION FACTOR NRF2;

ADAPTIVE IMMUNITY; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CATALYSIS; ENZYME SUBUNIT; FEMALE; LUNG ALVEOLUS CELL; LUNG EDEMA; LUNG INJURY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; FEMALE; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; LIPID PEROXIDATION; LUNG; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; NANOPARTICLES; NF-E2-RELATED FACTOR 2; ORGAN SIZE; OXIDATIVE STRESS; PNEUMOCYTES; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; TIME FACTORS; TITANIUM;

EID: 84865648994     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34190     Document Type: Article

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