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Volumn 18, Issue 23, 1999, Pages 6619-6629

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

Author keywords

Chromosomal aberration; Double strand break repair; DT40; Homologous recombination; Mre11

Indexed keywords

DNA; DNA BINDING PROTEIN; DOUBLE STRANDED DNA;

EID: 0033485758     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.23.6619     Document Type: Article
Times cited : (245)

References (64)
  • 2
    • 0027476083 scopus 로고
    • Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae
    • Ajimura, M., Leem, S.H. and Ogawa, H. (1993) Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics, 133, 51-66.
    • (1993) Genetics , vol.133 , pp. 51-66
    • Ajimura, M.1    Leem, S.H.2    Ogawa, H.3
  • 5
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
    • Boulton, S.J. and Jackson, S.P. (1996a) Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res., 24, 4639-4648.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 6
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
    • Boulton, S.J. and Jackson, S.P. (1996b) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J., 15, 5093-5103.
    • (1996) EMBO J. , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 7
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton, S.J. and Jackson, S.P. (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J., 17, 1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 8
    • 0025936509 scopus 로고
    • Increased ratio of targeted to random integration after transfection of chicken B cell lines
    • Buerstedde, J.M. and Takeda, S. (1991) Increased ratio of targeted to random integration after transfection of chicken B cell lines. Cell, 67, 179-188.
    • (1991) Cell , vol.67 , pp. 179-188
    • Buerstedde, J.M.1    Takeda, S.2
  • 10
    • 0032076248 scopus 로고    scopus 로고
    • The hMre11/ hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • Carney, J.P., Maser, R.S., Olivares, H., Davis, E.M., Le Beau, M., Yates III, J.R., Hays, L., Morgan, W.F. and Petrini, J.H. (1998) The hMre11/ hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell, 93, 477-486.
    • (1998) Cell , vol.93 , pp. 477-486
    • Carney, J.P.1    Maser, R.S.2    Olivares, H.3    Davis, E.M.4    Le Beau, M.5    Yates J.R. III6    Hays, L.7    Morgan, W.F.8    Petrini, J.H.9
  • 11
    • 0029056905 scopus 로고
    • Eleven polish patients with microcephaly, immunodeficiency and chromosomal instability: The Nijmegen breakage syndrome
    • Chrzanowska, K.H. et al. (1995) Eleven Polish patients with microcephaly, immunodeficiency and chromosomal instability: the Nijmegen breakage syndrome. Am. J. Med. Genet., 57, 462-471.
    • (1995) Am. J. Med. Genet. , vol.57 , pp. 462-471
    • Chrzanowska, K.H.1
  • 12
    • 0023110664 scopus 로고
    • Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. II. Induction of sister-chromatid exchanges and chromosomal aberrations by X-rays and UV-irradiation and their modulation by inhibitors of poly(ADP-ribose) synthetase and α-polymerase
    • Darroudi, F. and Natarajan, A.T. (1987) Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. II. Induction of sister-chromatid exchanges and chromosomal aberrations by X-rays and UV-irradiation and their modulation by inhibitors of poly(ADP-ribose) synthetase and α-polymerase. Mutat. Res., 177, 149-160.
    • (1987) Mutat. Res. , vol.177 , pp. 149-160
    • Darroudi, F.1    Natarajan, A.T.2
  • 13
    • 0029742576 scopus 로고    scopus 로고
    • Human Rad50 is physically associated with human Mre11: Identification of a conserved multiprotein complex implicated in recombinational DNA repair
    • Dolganov, G.M., Maser, R.S., Novikov, A., Tosto, L., Chong, S., Bressan, D.A. and Petrini, J.H. (1996) Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol. Cell. Biol., 16, 4832-4841.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4832-4841
    • Dolganov, G.M.1    Maser, R.S.2    Novikov, A.3    Tosto, L.4    Chong, S.5    Bressan, D.A.6    Petrini, J.H.7
  • 15
    • 0032476658 scopus 로고    scopus 로고
    • Distinct roles of two separable in vitro activities of yeast mre11 in mitotic and meiotic recombination
    • Furuse, M., Nagase, Y., Tsubouchi, H., Murakami-Murofushi, K., Shibata, T. and Ohta, K. (1998) Distinct roles of two separable in vitro activities of yeast mre11 in mitotic and meiotic recombination. EMBO J., 17, 6412-6425.
    • (1998) EMBO J. , vol.17 , pp. 6412-6425
    • Furuse, M.1    Nagase, Y.2    Tsubouchi, H.3    Murakami-Murofushi, K.4    Shibata, T.5    Ohta, K.6
  • 16
    • 0032527973 scopus 로고    scopus 로고
    • Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
    • Gasior, S.L., Wong, A.K., Kora, Y., Shinohara, A. and Bishop, D.K. (1998) Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev., 12, 2208-2221.
    • (1998) Genes Dev. , vol.12 , pp. 2208-2221
    • Gasior, S.L.1    Wong, A.K.2    Kora, Y.3    Shinohara, A.4    Bishop, D.K.5
  • 17
    • 0032516654 scopus 로고    scopus 로고
    • BRCA1 required for transcription-coupled repair of oxidative DNA damage
    • Gowen, L.C., Avrutskaya, A.V., Latour, A.M., Koller, B.H. and Leadon, S.A. (1998) BRCA1 required for transcription-coupled repair of oxidative DNA damage. Science, 281, 1009-1012.
    • (1998) Science , vol.281 , pp. 1009-1012
    • Gowen, L.C.1    Avrutskaya, A.V.2    Latour, A.M.3    Koller, B.H.4    Leadon, S.A.5
  • 18
    • 0028957889 scopus 로고
    • Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes
    • Haaf, T., Golub, E.I., Reddy, G., Radding, C.M. and Ward, D.C. (1995) Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc. Natl Acad. Sci. USA, 92, 2298-2302.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2298-2302
    • Haaf, T.1    Golub, E.I.2    Reddy, G.3    Radding, C.M.4    Ward, D.C.5
  • 19
    • 0032567041 scopus 로고    scopus 로고
    • The many interfaces of Mre11
    • Haber, J.E. (1998) The many interfaces of Mre11. Cell, 95, 583-586.
    • (1998) Cell , vol.95 , pp. 583-586
    • Haber, J.E.1
  • 20
    • 0031155346 scopus 로고    scopus 로고
    • Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: Effects of mitotic inhibitors on cell cycle progression
    • Haraguchi, T., Kaneda, T. and Hiraoka, Y. (1997) Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: effects of mitotic inhibitors on cell cycle progression. Genes Cells, 2, 369-380.
    • (1997) Genes Cells , vol.2 , pp. 369-380
    • Haraguchi, T.1    Kaneda, T.2    Hiraoka, Y.3
  • 21
    • 84959678845 scopus 로고
    • A mechanism for gene conversion in fungi
    • Holliday, R. (1964) A mechanism for gene conversion in fungi. Genet. Res., 5, 282-304.
    • (1964) Genet. Res. , vol.5 , pp. 282-304
    • Holliday, R.1
  • 22
    • 0028914077 scopus 로고
    • Interaction of Mre11 and Rad50: Two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae
    • Johzuka, K. and Ogawa, H. (1995) Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics, 139, 1521-1532.
    • (1995) Genetics , vol.139 , pp. 1521-1532
    • Johzuka, K.1    Ogawa, H.2
  • 23
    • 0022968662 scopus 로고
    • Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line
    • Kemp, L.M. and Jeggo, P.A. (1986) Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line. Mutat. Res., 166, 255-263.
    • (1986) Mutat. Res. , vol.166 , pp. 255-263
    • Kemp, L.M.1    Jeggo, P.A.2
  • 24
    • 0032535478 scopus 로고    scopus 로고
    • Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: Requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I
    • Kobayashi, T., Heck, D.J., Nomura, M. and Horiuchi, T. (1998) Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I. Genes Dev., 12, 3821-3830.
    • (1998) Genes Dev. , vol.12 , pp. 3821-3830
    • Kobayashi, T.1    Heck, D.J.2    Nomura, M.3    Horiuchi, T.4
  • 25
    • 0028308710 scopus 로고
    • Homologous pairing and DNA strand-exchange proteins
    • Kowalczykowski, S.C. and Eggleston, A.K. (1994) Homologous pairing and DNA strand-exchange proteins. Annu. Rev. Biochem., 63, 991-1043.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 991-1043
    • Kowalczykowski, S.C.1    Eggleston, A.K.2
  • 26
    • 0032061317 scopus 로고    scopus 로고
    • XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages
    • Liu, N. et al. (1998) XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages. Mol. Cell, 1, 783-793.
    • (1998) Mol. Cell , vol.1 , pp. 783-793
    • Liu, N.1
  • 27
    • 0033557572 scopus 로고    scopus 로고
    • p21 (cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy and relaxed microtubule damage checkpoints in human hematopoietic cells
    • Mantel, C., Braun, S.E., Reid, S., Henegariu, O., Liu, L., Hangoc, G. and Broxmeyer, H.E. (1999) p21 (cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy and relaxed microtubule damage checkpoints in human hematopoietic cells. Blood, 93, 1390-1398.
    • (1999) Blood , vol.93 , pp. 1390-1398
    • Mantel, C.1    Braun, S.E.2    Reid, S.3    Henegariu, O.4    Liu, L.5    Hangoc, G.6    Broxmeyer, H.E.7
  • 28
    • 0030764691 scopus 로고    scopus 로고
    • hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
    • Maser, R.S., Monsen, K.J., Nelms, B.E. and Petrini, J.H. (1997) hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol. Cell. Biol., 17, 6087-6096.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6087-6096
    • Maser, R.S.1    Monsen, K.J.2    Nelms, B.E.3    Petrini, J.H.4
  • 29
    • 17344372572 scopus 로고    scopus 로고
    • Positional cloning of the gene for Nijmegen breakage syndrome
    • Matsuura, S. et al. (1998) Positional cloning of the gene for Nijmegen breakage syndrome. Nature Genet., 19, 179-181.
    • (1998) Nature Genet. , vol.19 , pp. 179-181
    • Matsuura, S.1
  • 30
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore, J.K. and Haber, J.E. (1996) Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 31
    • 0032931844 scopus 로고    scopus 로고
    • The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end-joining, or telomere maintenance
    • Moreau, S., Ferguson, J.R. and Symington, L.S. (1999) The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end-joining, or telomere maintenance. Mol. Cell. Biol., 19, 556-566.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 556-566
    • Moreau, S.1    Ferguson, J.R.2    Symington, L.S.3
  • 32
    • 0032085295 scopus 로고    scopus 로고
    • The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
    • Paull, T.T. and Gellert, M. (1998) The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol. Cell, 1, 969-979.
    • (1998) Mol. Cell , vol.1 , pp. 969-979
    • Paull, T.T.1    Gellert, M.2
  • 33
    • 0033563229 scopus 로고    scopus 로고
    • Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
    • Paull, T.T. and Gellert, M. (1999) Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev., 13, 1276-1288.
    • (1999) Genes Dev. , vol.13 , pp. 1276-1288
    • Paull, T.T.1    Gellert, M.2
  • 36
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • Scully, R., Chen, J., Ochs, R.L., Keegan, K., Hoekstra, M., Feunteun, J. and Livingston, D.M. (1997a) Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell, 90, 425-435.
    • (1997) Cell , vol.90 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3    Keegan, K.4    Hoekstra, M.5    Feunteun, J.6    Livingston, D.M.7
  • 38
    • 0032582794 scopus 로고    scopus 로고
    • RuvAB acts at arrested replication forks
    • Seigneur, M., Bidnenko, V., Ehrlich, S.D. and Michel, B. (1998) RuvAB acts at arrested replication forks, Cell, 95, 419-430.
    • (1998) Cell , vol.95 , pp. 419-430
    • Seigneur, M.1    Bidnenko, V.2    Ehrlich, S.D.3    Michel, B.4
  • 39
    • 0026751113 scopus 로고
    • Rad51 protein involved in repair and recombination in S.cerevisiae is a RecA-like protein
    • published erratum appears in Cell, 71, 180
    • Shinohara, A., Ogawa, H. and Ogawa, T. (1992) Rad51 protein involved in repair and recombination in S.cerevisiae is a RecA-like protein. Cell, 69, 457-470 [published erratum appears in Cell, 71, 180].
    • (1992) Cell , vol.69 , pp. 457-470
    • Shinohara, A.1    Ogawa, H.2    Ogawa, T.3
  • 40
    • 0031242008 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination
    • Shinohara, A., Gasior, S., Ogawa,T., Kleckner, N. and Bishop, D.K. (1997) Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination. Genes Cells, 2, 615-629.
    • (1997) Genes Cells , vol.2 , pp. 615-629
    • Shinohara, A.1    Gasior, S.2    Kleckner, N.3    Bishop, D.K.4
  • 41
    • 0030033061 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination
    • Siede, W., Friedl, A.A., Dianova, I., Eckardt-Schupp, F. and Friedberg, E.C. (1996) The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics, 142, 91-102.
    • (1996) Genetics , vol.142 , pp. 91-102
    • Siede, W.1    Friedl, A.A.2    Dianova, I.3    Eckardt-Schupp, F.4    Friedberg, E.C.5
  • 42
    • 0026636626 scopus 로고
    • Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells
    • Smith, K.A., Stark, M.B., Gorman, P.A. and Stark, G.R. (1992) Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells. Proc. Natl Acad. Sci. USA, 89, 5427-5431.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 5427-5431
    • Smith, K.A.1    Stark, M.B.2    Gorman, P.A.3    Stark, G.R.4
  • 44
  • 45
    • 0031007450 scopus 로고    scopus 로고
    • Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor
    • Sugawara, H., Kurosaki, M., Takata, M. and Kurosaki, T. (1997) Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. EMBO J., 16, 3078-3088.
    • (1997) EMBO J. , vol.16 , pp. 3078-3088
    • Sugawara, H.1    Kurosaki, M.2    Takata, M.3    Kurosaki, T.4
  • 46
    • 0026530911 scopus 로고
    • Characterization of double-strand break-induced recombination: Homology requirements and single-stranded DNA formation
    • Sugawara, N. and Haber, J.E. (1992) Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol., 12, 563-575.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 563-575
    • Sugawara, N.1    Haber, J.E.2
  • 47
    • 0029112483 scopus 로고
    • DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA
    • Sung, P. and Robberson, D.L. (1995) DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. Cell, 82,453-461.
    • (1995) Cell , vol.82 , pp. 453-461
    • Sung, P.1    Robberson, D.L.2
  • 49
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata, M., Sasaki, M.S., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchi-Iwai, Y., Shinohara, A. and Takeda, S. (1998) Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J., 17, 5497-5508.
    • (1998) EMBO J. , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6    Yamaguchi-Iwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 50
    • 0029949916 scopus 로고    scopus 로고
    • S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes
    • Tashiro, S., Kotomura, N., Shinohara, A., Tanaka, K., Ueda, K. and Kamada, N. (1996) S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes. Oncogene, 12, 2165-2170.
    • (1996) Oncogene , vol.12 , pp. 2165-2170
    • Tashiro, S.1    Kotomura, N.2    Shinohara, A.3    Tanaka, K.4    Ueda, K.5    Kamada, N.6
  • 51
    • 0028962663 scopus 로고
    • Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: A gene required for repair of double strand breaks and recombination
    • Tavassoli, M., Shayeghi, M., Nasim, A. and Watts, F.Z. (1995) Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: a gene required for repair of double strand breaks and recombination. Nucleic Acids Res., 23, 383-388.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 383-388
    • Tavassoli, M.1    Shayeghi, M.2    Nasim, A.3    Watts, F.Z.4
  • 52
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo, S.-H. and Jackson, S.P. (1997) Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J., 16, 4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.-H.1    Jackson, S.P.2
  • 53
    • 0032555480 scopus 로고    scopus 로고
    • Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11 and p95
    • Trujillo, K.M., Yuan, S.S., Lee, E.Y. and Sung, P. (1998) Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11 and p95. J. Biol. Chem., 273, 21447-21450.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21447-21450
    • Trujillo, K.M.1    Yuan, S.S.2    Lee, E.Y.3    Sung, P.4
  • 54
    • 0031983191 scopus 로고    scopus 로고
    • A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis
    • Tsubouchi, H. and Ogawa, H. (1998) A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis. Mol. Cell. Biol., 18, 260-268.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 260-268
    • Tsubouchi, H.1    Ogawa, H.2
  • 55
    • 0026717314 scopus 로고
    • Immortalization of conditionally transformed chicken cells: Loss of normal p53 expression is an early step that is independent of cell transformation
    • Ulrich, E., Boehmelt, G., Bird, A. and Beug, H. (1992) Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation. Genes Dev., 6, 876-887.
    • (1992) Genes Dev. , vol.6 , pp. 876-887
    • Ulrich, E.1    Boehmelt, G.2    Bird, A.3    Beug, H.4
  • 56
    • 0032567108 scopus 로고    scopus 로고
    • Complex formation and functional versatility of Mre11 of budding yeast in recombination
    • Usui, T., Ohta, T., Oshiumi, H., Tomizawa, J., Ogawa, H. and Ogawa, T. (1998) Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell, 95, 705-716.
    • (1998) Cell , vol.95 , pp. 705-716
    • Usui, T.1    Ohta, T.2    Oshiumi, H.3    Tomizawa, J.4    Ogawa, H.5    Ogawa, T.6
  • 58
    • 0032076190 scopus 로고    scopus 로고
    • Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
    • Varon, R. et al. (1998) Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell, 93,467-476.
    • (1998) Cell , vol.93 , pp. 467-476
    • Varon, R.1
  • 60
    • 0025020278 scopus 로고
    • Intermediates of recombination during mating type switching in Saccharomyces cerevisiae
    • White, C.I. and Haber, J.E. (1990) Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J., 9, 663-673.
    • (1990) EMBO J. , vol.9 , pp. 663-673
    • White, C.I.1    Haber, J.E.2
  • 61
    • 0030749867 scopus 로고    scopus 로고
    • Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells
    • Xiao, Y. and Weaver, D.T. (1997) Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucleic Acids Res., 25, 2985-2991.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2985-2991
    • Xiao, Y.1    Weaver, D.T.2
  • 64
    • 0031444239 scopus 로고    scopus 로고
    • Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism
    • Zou, H. and Rothstein, R. (1997) Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell, 90, 87-96.
    • (1997) Cell , vol.90 , pp. 87-96
    • Zou, H.1    Rothstein, R.2


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