Mta2 promotes Tipin-dependent maintenance of replication fork integrity

Cell Cycle

Volumn 13, Issue 13, 2014, Pages 2120-2128

  Errico, Alessia ^a   Aze, Antoine ^b   Costanzo, Vincenzo ^b  

^a London Research Institute   (United Kingdom)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

Centromeres; DNA replication; Heterochromatin; Histone deacetylase; Replicaiton fork integrity; Xenopus laevis

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; KIDNEY INJURY MOLECULE 1; MTA2 PROTEIN; PO ALPHA PROTEIN; POL PROTEIN; PROTEIN; PSORALEN; REPETITIVE DNA; TIPIN PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CHROMATIN; DNA; DNA DIRECTED DNA POLYMERASE BETA; HISTONE DEACETYLASE; MTA2 PROTEIN, XENOPUS; REPRESSOR PROTEIN; TIPIN PROTEIN, XENOPUS; XENOPUS PROTEIN;

ANIMAL CELL; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY DEVICE; CELL CYCLE S PHASE; CELL DIVISION; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; DNA BINDING; DNA REPLICATION; DNA REPLICATION ORIGIN; DNA SEQUENCE; DNA TEMPLATE; FEMALE; HETEROCHROMATIN; HISTONE MODIFICATION; INTERPHASE; NONHUMAN; PHENOTYPE; RETICULOCYTE; XENOPUS LAEVIS; ANIMAL; CENTROMERE; GENE LOCUS; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; CARRIER PROTEINS; CENTROMERE; CHROMATIN; DNA; DNA POLYMERASE I; DNA REPLICATION; GENETIC LOCI; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; REPRESSOR PROTEINS; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 84903789589     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.29157     Document Type: Article

References (35)

1. Diffley JF. Regulation of early events in chromosome replication. Curr Biol 2004; 14:R778-86; PMID:15380092; http://dx.doi.org/10.1016/j.cub.2004.09. 019.
2. Errico A, Costanzo V. Mechanisms of replication fork protection: a safeguard for genome stability. Crit Rev Biochem Mol Biol 2012; 47:222-35; PMID:22324461; http://dx.doi.org/10.3109/10409 238.2012.655374.
3. Aria V, De Felice M, Di Perna R, Uno S, Masai H, Syväoja JE, van Loon B, Hübscher U, Pisani FM. The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity. J Biol Chem 2013; 288:12742-52; PMID:23511638; http://dx.doi.org/10.1074/jbc.M112. 398073.
4. Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J. Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage. Mol Cell 2000; 6:649-59; PMID:11030344; http://dx.doi.org/10.1016/S1097-2765(00)00063-0.
5. Costanzo V, Robertson K, Gautier J. Xenopus cell-free extracts to study the DNA damage response. Methods Mol Biol 2004; 280:213-27; PMID:15187256.
6. Costanzo V, Gautier J. Xenopus cell-free extracts to study DNA damage checkpoints. Methods Mol Biol 2004; 241:255-67; PMID:14970660.
7. Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V. GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. Nat Cell Biol 2010; 12:484-91; PMID:20383140; http://dx.doi.org/10.1038/ncb2050.
8. Errico A, Cosentino C, Rivera T, Losada A, Schwob E, Hunt T, Costanzo V. Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. EMBO J 2009; 28:3681-92; PMID:19893489; http://dx.doi.org/ 10.1038/emboj.2009.304.
9. Errico A, Costanzo V, Hunt T. Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts. Proc Natl Acad Sci USA 2007; 104:14929-34; PMID:17846426; http://dx.doi.org/10.1073/pnas.0706347104.
10. Hashimoto Y, Ray Chaudhuri A, Lopes M, Costanzo V. Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nat Struct Mol Biol 2010; 17:1305-11; PMID:20935632; http://dx.doi.org/10.1038/ nsmb.1927.
11. Hashimoto Y, Costanzo V. Studying DNA replication fork stability in Xenopus egg extract. Methods Mol Biol 2011; 745:437-45; PMID:21660709; http://dx.doi.org/10.1007/978-1-61779-129-1-25.
12. Hashimoto Y, Takisawa H. Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. EMBO J 2003; 22:2526-35; PMID:12743046; http://dx.doi.org/10.1093/emboj/cdg238.
13. Shechter D, Costanzo V, Gautier J. Regulation of DNA replication by ATR: signaling in response to DNA intermediates. DNA Repair (Amst) 2004; 3:901-8; PMID:15279775; http://dx.doi.org/10.1016/j.dnarep.2004.03.020.
14. Trenz K, Errico A, Costanzo V. Plx1 is required for chromosomal DNA replication under stressful conditions. EMBO J 2008; 27:876-85; PMID:18309293; http://dx.doi.org/10.1038/emboj.2008.29.
15. Trenz K, Smith E, Smith S, Costanzo V. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks. EMBO J 2006; 25:1764-74; PMID:16601701; http://dx.doi.org/10.1038/sj. emboj.7601045.
16. Ray Chaudhuri A, Hashimoto Y, Herrador R, Neelsen KJ, Fachinetti D, Bermejo R, Cocito A, Costanzo V, Lopes M. Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nat Struct Mol Biol 2012; 19:417-23; PMID:22388737; http://dx.doi.org/10.1038/nsmb.2258.
17. Denslow SA, Wade PA. The human Mi-2/NuRD complex and gene regulation. Oncogene 2007; 26:5433-8; PMID:17694084; http://dx.doi.org/10.1038/sj.onc. 1210611.
18. Lopes M. Electron microscopy methods for studying in vivo DNA replication intermediates. Methods Mol Biol 2009; 521:605-31; PMID:19563131; http://dx.doi.org/10.1007/978-1-60327-815-7-34.
19. Feng Q, Zhang Y. The NuRD complex: linking histone modification to nucleosome remodeling. Curr Top Microbiol Immunol 2003; 274:269-90; PMID:12596911; http://dx.doi.org/10.1007/978-3-642-55747-7-10.
20. Xue Y, Wong J, Moreno GT, Young MK, Côté J, Wang W. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol Cell 1998; 2:851-61; PMID:9885572; http://dx.doi.org/10.1016/S1097-2765(00)80299-3.
21. Bowen NJ, Fujita N, Kajita M, Wade PA. Mi-2/NuRD: multiple complexes for many purposes. Biochim Biophys Acta 2004; 1677:52-7; PMID:15020045
22. Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev 1999; 13:1924-35; PMID:10444591; http://dx.doi.org/10.1101/gad.13.15.1924.
23. Smeenk G, Wiegant WW, Vrolijk H, Solari AP, Pastink A, van Attikum H. The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage. J Cell Biol 2010; 190:741-9; PMID:20805320; http://dx.doi.org/10.1083/jcb. 201001048.
24. Sims JK, Wade PA. Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin. Mol Biol Cell 2011; 22:3094-102; PMID:21737684; http://dx.doi.org/10.1091/mbc.E11-03-0258.
25. Newport J, Kirschner M. A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 1982; 30:687-96; PMID:7139712; http://dx.doi.org/10.1016/0092-8674(82)90273-2.
26. Ge XQ, Jackson DA, Blow JJ. Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. Genes Dev 2007; 21:3331-41; PMID:18079179; http://dx.doi.org/10.1101/gad.457807.
27. Errico A, Costanzo V. Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns. EMBO Rep 2010; 11:270-8; PMID:20203697; http://dx.doi.org/10.1038/embor.2010.27.
28. Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R, et al. Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol 2013; 20:347-54; PMID:23396353; http://dx.doi.org/10.1038/nsmb.2501.
29. Bétous R, Mason AC, Rambo RP, Bansbach CE, Badu-Nkansah A, Sirbu BM, Eichman BF, Cortez D. SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication. Genes Dev 2012; 26:151-62; PMID:22279047; http://dx.doi.org/10.1101/gad.178459.111.
30. Polo SE, Kaidi A, Baskcomb L, Galanty Y, Jackson SP. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4. EMBO J 2010; 29:3130-9; PMID:20693977; http://dx.doi.org/10.1038/ emboj.2010.188.
31. Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiácovo MP, Elledge SJ. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc Natl Acad Sci USA 2010; 107:18475-80; PMID:20937877; http://dx.doi.org/10.1073/pnas.1012946107.
32. Brehm A, Nielsen SJ, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J 1999; 18:2449-58; PMID:10228159; http://dx.doi.org/10.1093/emboj/18.9.2449.
33. Helbling Chadwick L, Chadwick BP, Jaye DL, Wade PA. The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cells. Chromosoma 2009; 118:445-57; PMID:19296121; http://dx.doi.org/10.1007/s00412-009-0207-7.
34. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 2009; 325:834-40; PMID:19608861; http://dx.doi.org/10.1126/science.1175371.
35. Tugal T, Zou-Yang XH, Gavin K, Pappin D, Canas B, Kobayashi R, Hunt T, Stillman B. The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p. J Biol Chem 1998; 273:32421-9; PMID:9829972; http://dx.doi.org/10.1074/jbc.273.49.32421.