Linking DNA polymerase theta structure and function in health and disease

Cellular and Molecular Life Sciences

Volumn 73, Issue 3, 2016, Pages 603-615

  Beagan, Kelly ^a   McVey, Mitch ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Carcinogenesis; Helicase; Homologous recombination; Indels; MMEJ; Translesion synthesis

Indexed keywords

DNA POLYMERASE; DNA POLYMERASE THETA; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE;

CANCER GROWTH; DISEASE ASSOCIATION; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DRUG TARGETING; ENZYME ACTIVITY; ENZYME STRUCTURE; GENOMIC INSTABILITY; HUMAN; MICROHOMOLOGY MEDIATED END JOINING; NONHUMAN; PROTEIN EXPRESSION; REVIEW; STRUCTURE ANALYSIS; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; GENETICS; MOLECULAR MODEL; NEOPLASM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; GENOMIC INSTABILITY; HUMANS; MODELS, GENETIC; MODELS, MOLECULAR; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84954516256     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-2078-9     Document Type: Review

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