A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

Molecular Cell

Volumn 59, Issue 3, 2015, Pages 478-490

  Wang, Anderson T ^a   Kim, Taeho ^b   Wagner, John E ^c   Conti, Brooke A ^a   Lach, Francis P ^a   Huang, Athena L ^a   Molina, Henrik ^a   Sanborn, Erica M ^a   Zierhut, Heather ^c   Cornes, Belinda K ^d   Abhyankar, Avinash ^d   Sougnez, Carrie ^e   Gabriel, Stacey B ^e   Auerbach, Arleen D ^a   Kowalczykowski, Stephen C ^b   Smogorzewska, Agata ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d NEW YORK GENOME CENTER   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MESSENGER RNA; MUTANT PROTEIN; RAD51 PROTEIN; REPLICATION FACTOR A; WERNER SYNDROME PROTEIN; CROSS LINKING REAGENT; DNA; DNA HELICASE; DNA2 PROTEIN, HUMAN; EXODEOXYRIBONUCLEASE; RAD51 PROTEIN, HUMAN; RECQ HELICASE; RPA1 PROTEIN, HUMAN; WRN PROTEIN, HUMAN;

ALLELE; ARTICLE; CASE REPORT; CHILD; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; DNA CROSS LINKING; DNA END JOINING REPAIR; DNA REPAIR; DNA STRAND; FANCONI ANEMIA; FEMALE; FRAMESHIFT MUTATION; GENE DISRUPTION; GENE EXPRESSION; GENETIC COMPLEMENTATION; HETEROZYGOSITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PHENOTYPE; PRESCHOOL CHILD; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; WILD TYPE; CELL SURVIVAL; GENETICS; GENOMIC INSTABILITY; HEK293 CELL LINE; HETEROZYGOTE; INFANT; METABOLISM; MUTATION;

CELL SURVIVAL; CROSS-LINKING REAGENTS; DNA; DNA HELICASES; DNA REPAIR; EXODEOXYRIBONUCLEASES; FANCONI ANEMIA; FEMALE; GENOMIC INSTABILITY; HEK293 CELLS; HETEROZYGOTE; HUMANS; INFANT; MUTATION; RAD51 RECOMBINASE; RECQ HELICASES; REPLICATION PROTEIN A;

EID: 84938579589     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.07.009     Document Type: Article

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