Priming for tolerance and cohesion at replication forks

Nucleus

Volumn 7, Issue 1, 2016, Pages 8-12

  Branzei, Dana ^a   Szakal, Barnabas ^a  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

Chromosome replication; DNA damage tolerance; fork reversal recombination; repriming; sister chromatid cohesion

Indexed keywords

HELICASE; CTF4 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE BETA; DNA PRIMASE; FUNGAL DNA; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CELL ADHESION; CHROMATID ABERRATION; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; EPIGENETICS; GENE MUTATION; GENETIC RECOMBINATION; HUMAN; IMMUNOLOGICAL TOLERANCE; MICROSCOPY; MUTAGENESIS; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; BIOSYNTHESIS; GENETICS; METABOLISM; PHYSIOLOGY;

DNA POLYMERASE I; DNA PRIMASE; DNA REPLICATION; DNA, FUNGAL; DNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84961198060     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.1080/19491034.2016.1149663     Document Type: Article

References (23)

1. M.Fumasoni, K.Zwicky, F.Vanoli, M.Lopes, D.Branzei. Error-Free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polalpha/Primase/Ctf4 Complex. Mol Cell 2015; 57:812-23; PMID:25661486; http://dx.doi.org/10.1016/j.molcel.2014.12.038
2. D.Branzei, M.Foiani. Maintaining genome stability at the replication fork. Nat Rev Mol Cell Biol 2010; 11:208-19; PMID:20177396; http://dx.doi.org/10.1038/nrm2852
3. D.Branzei. Ubiquitin family modifications and template switching. FEBS Lett 2011; 585:2810-7; PMID:21539841; http://dx.doi.org/10.1016/j.febslet.2011.04.053
4. G.I.Karras, M.Fumasoni, G.Sienski, F.Vanoli, D.Branzei, S.Jentsch. Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Mol Cell 2013; 49:536-46; PMID:23260657; http://dx.doi.org/10.1016/j.molcel.2012.11.016
5. V.Gonzalez-Huici, B.Szakal, M.Urulangodi, I.Psakhye, F.Castellucci, D.Menolfi, E.Rajakumara, M.Fumasoni, R.Bermejo, S.Jentsch, et al. DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J 2014; 33:327-40; PMID:24473148; http://dx.doi.org/10.1002/embj.201387425
6. G.I.Lang, A.W.Murray. Mutation rates across budding yeast chromosome VI are correlated with replication timing. Genome Biol Evol 2011; 3:799-811; PMID:21666225; http://dx.doi.org/10.1093/gbe/evr054
7. J.A.Stamatoyannopoulos, I.Adzhubei, R.E.Thurman, G.V.Kryukov, S.M.Mirkin, S.R.Sunyaev. Human mutation rate associated with DNA replication timing. Nat Genet 2009; 41:393-5; PMID:19287383; http://dx.doi.org/10.1038/ng.363
8. K.D.Makova, R.C.Hardison. The effects of chromatin organization on variation in mutation rates in the genome. Nat Rev Genet 2015; 16:213-23; PMID:25732611; http://dx.doi.org/10.1038/nrg3890
9. B.Schuster-Bockler, B.Lehner. Chromatin organization is a major influence on regional mutation rates in human cancer cells. Nature 2012; 488:504-7; PMID:22820252; http://dx.doi.org/10.1038/nature11273
10. M.Fragkos, O.Ganier, P.Coulombe, M.Mechali. DNA replication origin activation in space and time. Nat Rev Mol Cell Biol 2015; 16:360-74; PMID:25999062; http://dx.doi.org/10.1038/nrm4002
11. G.I.Karras, S.Jentsch. The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. Cell 2010; 141:255-67; PMID:20403322; http://dx.doi.org/10.1016/j.cell.2010.02.028
12. Y.Daigaku, A.A.Davies, H.D.Ulrich. Ubiquitin-dependent DNA damage bypass is separable from genome replication. Nature 2010; 465:951-5; PMID:20453836; http://dx.doi.org/10.1038/nature09097
13. M.Giannattasio, K.Zwicky, C.Follonier, M.Foiani, M.Lopes, D.Branzei. Visualization of recombination-mediated damage bypass by template switching. Nat Struct Mol Biol 2014; 21:884-92; PMID:25195051; http://dx.doi.org/10.1038/nsmb.2888
14. A.C.Simon, J.C.Zhou, R.L.Perera, F.van Deursen, C.Evrin, M.E.Ivanova, M.L.Kilkenny, L.Renault, S.Kjaer, D.Matak-Vinković, et al. A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome. Nature 2014; 510:293-7; PMID:24805245; http://dx.doi.org/10.1038/nature13234
15. J.S.Hanna, E.S.Kroll, V.Lundblad, F.A.Spencer. Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion. Mol Cell Biol 2001; 21:3144-58; PMID:11287619; http://dx.doi.org/10.1128/MCB.21.9.3144-3158.2001
16. J.M.Peters, T.Nishiyama. Sister chromatid cohesion. Cold Spring Harbor Perspect Biol 2012; 4:a011130; http://dx.doi.org/10.1101/cshperspect.a011130
17. H.Xu, C.Boone, G.W.Brown. Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics 2007; 176:1417-29; PMID:17483413; http://dx.doi.org/10.1534/genetics.107.072876
18. M.Tittel-Elmer, A.Lengronne, M.B.Davidson, J.Bacal, P.Francois, M.Hohl, J.H.Petrini, P.Pasero, J.A.Cobb. Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell 2012; 48:98-108; PMID:22885006; http://dx.doi.org/10.1016/j.molcel.2012.07.004
19. S.Covo, J.W.Westmoreland, D.A.Gordenin, M.A.Resnick. Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes. PLoS Genetics 2010; 6:e1001006
20. A.F.Straight, A.S.Belmont, C.C.Robinett, A.W.Murray. GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion. Curr Biol 1996; 6:1599-608; PMID:8994824; http://dx.doi.org/10.1016/S0960-9822(02)70783-5
21. R.V.Skibbens. Establishment of sister chromatid cohesion. Curr Biol 2009; 19:R1126-32; PMID:20064425; http://dx.doi.org/10.1016/j.cub.2009.10.067
22. R.A.Burrell, S.E.McClelland, D.Endesfelder, P.Groth, M.C.Weller, N.Shaikh, E.Domingo, N.Kanu, S.M.Dewhurst, E.Gronroos, et al. Replication stress links structural and numerical cancer chromosomal instability. Nature 2013; 494:492-6; PMID:23446422; http://dx.doi.org/10.1038/nature11935
23. A.Losada. Cohesin in cancer: chromosome segregation and beyond. Nat Rev Cancer 2014; 14:389-93; PMID:24854081; http://dx.doi.org/10.1038/nrc3743