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Volumn 27, Issue 1, 2017, Pages 1-16

Neuroinflammatory genes associated with post-traumatic stress disorder: Implications for comorbidity

Author keywords

C reactive protein; Comorbidity; Cytokines; Gene expression; Glucocorticoid receptor; Inflammation; Neuroinflammation; Nuclear factor ; Post traumatic stress disorder; Single nucleotide polymorphisms

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; FK 506 BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STAT5B PROTEIN;

EID: 84987920179     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0000000000000143     Document Type: Review
Times cited : (39)

References (221)
  • 1
    • 84886749767 scopus 로고    scopus 로고
    • Human c-reactive protein gene polymorphism and metabolic syndrome are associated with premature coronary artery disease
    • Abd El-Aziz TA, Mohamed RH (2013). Human C-reactive protein gene polymorphism and metabolic syndrome are associated with premature coronary artery disease. Gene 532:216-221.
    • (2013) Gene , vol.532 , pp. 216-221
    • Abd El-Aziz, T.A.1    Mohamed, R.H.2
  • 2
    • 78751704549 scopus 로고    scopus 로고
    • Hpa axis responsiveness to stress: Implications for healthy aging
    • Aguilera G (2011). HPA axis responsiveness to stress: implications for healthy aging. Exp Gerontol 46:90-95.
    • (2011) Exp Gerontol , vol.46 , pp. 90-95
    • Aguilera, G.1
  • 3
    • 68949129022 scopus 로고    scopus 로고
    • Polymorphisms of the crp gene inhibit inflammatory response and increase susceptibility to depression: The health in men study
    • Almeida OP, Norman PE, Allcock R, van Bockxmeer F, Hankey GJ, Jamrozik K, Flicker L (2009). Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study. Int J Epidemiol 38:1049-1059.
    • (2009) Int J Epidemiol , vol.38 , pp. 1049-1059
    • Almeida, O.P.1    Norman, P.E.2    Allcock, R.3    Van Bockxmeer, F.4    Hankey, G.J.5    Jamrozik, K.6    Flicker, L.7
  • 4
    • 0003472502 scopus 로고    scopus 로고
    • American Psychiatric Association, 5th ed Arlington, VA: American Psychiatric Publishing
    • American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Arlington, VA: American Psychiatric Publishing.
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 84927949424 scopus 로고    scopus 로고
    • C-reactive protein gene variants: Independent association with late-life depression and circulating protein levels
    • Ancelin ML, Farré A, Carriére I, Ritchie K, Chaudieu I, Ryan J (2015). C-reactive protein gene variants: independent association with late-life depression and circulating protein levels. Transl Psychiatry 5:e499.
    • (2015) Transl Psychiatry , vol.5 , pp. e499
    • Ancelin, M.L.1    Farré, A.2    Carriére, I.3    Ritchie, K.4    Chaudieu, I.5    Ryan, J.6
  • 8
    • 0034616230 scopus 로고    scopus 로고
    • Association between an interleukin-6 promoter and 3' flanking region haplotype and reduced Alzheimer's disease risk in a German population
    • Bagli M, Papassotiropoulos A, Knapp M, Jessen F, Luise Rao M, MaierW, Heun R (2000). Association between an interleukin-6 promoter and 3' flanking region haplotype and reduced Alzheimer's disease risk in a German population. Neurosci Lett 283:109-112.
    • (2000) Neurosci Lett , vol.283 , pp. 109-112
    • Bagli, M.1    Papassotiropoulos, A.2    Knapp, M.3    Jessen, F.4    Luise Rao, M.5    Maier, W.6    Heun, R.7
  • 9
    • 84957431527 scopus 로고    scopus 로고
    • Evidence for epigenetic regulation of pro-inflammatory cytokines, interleukin-12 and interferon gamma, in peripheral blood mononuclear cells from ptsd patients
    • Bam M, Yang X, Zhou J, Ginsberg JP, Leyden Q, Nagarkatti PS, Nagarkatti M (2016). Evidence for epigenetic regulation of pro-inflammatory cytokines, interleukin-12 and interferon gamma, in peripheral blood mononuclear cells from PTSD patients. J Neuroimmune Pharmacol 11:168-181.
    • (2016) J Neuroimmune Pharmacol , vol.11 , pp. 168-181
    • Bam, M.1    Yang, X.2    Zhou, J.3    Ginsberg, J.P.4    Leyden, Q.5    Nagarkatti, P.S.6    Nagarkatti, M.7
  • 11
    • 79959977446 scopus 로고    scopus 로고
    • Ifn-? Signaling, with the synergistic contribution of TNF-A, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease
    • Barcia C, Ros CM, Annese V, Gómez A, Ros-Bernal F, Aguado-Yera D, et al. (2011). IFN-? signaling, with the synergistic contribution of TNF-A, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease. Cell Death Dis 2:e142.
    • (2011) Cell Death Dis , vol.2 , pp. e142
    • Barcia, C.1    Ros, C.M.2    Annese, V.3    Gómez, A.4    Ros-Bernal, F.5    Aguado-Yera, D.6
  • 12
    • 84869873085 scopus 로고    scopus 로고
    • Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome
    • Beumer W, Drexhage RC, de Wit H, Versnel MA, Drexhage HA, Cohen D (2012). Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome. Psychoneuroendocrinology 37:1901-1911.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1901-1911
    • Beumer, W.1    Drexhage, R.C.2    De Wit, H.3    Versnel, M.A.4    Drexhage, H.A.5    Cohen, D.6
  • 13
    • 0034617348 scopus 로고    scopus 로고
    • Genetic polymorphisms in the cathespin d and interleukin-6 genes and the risk of Alzheimer's disease
    • Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI (2000). Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease. Neurosci Lett 288:21-24.
    • (2000) Neurosci Lett , vol.288 , pp. 21-24
    • Bhojak, T.J.1    DeKosky, S.T.2    Ganguli, M.3    Kamboh, M.I.4
  • 17
    • 40949142290 scopus 로고    scopus 로고
    • Association of fkbp5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults
    • Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, et al. (2008). Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299:1291-1305.
    • (2008) JAMA , vol.299 , pp. 1291-1305
    • Binder, E.B.1    Bradley, R.G.2    Liu, W.3    Epstein, M.P.4    Deveau, T.C.5    Mercer, K.B.6
  • 18
    • 84892868560 scopus 로고    scopus 로고
    • Hpa and sam axis responses as correlates of self-vs parental ratings of anxiety in boys with an autistic disorder
    • Bitsika V, Sharpley CF, Sweeney JA, McFarlane JR (2014). HPA and SAM axis responses as correlates of self-vs parental ratings of anxiety in boys with an autistic disorder. Physiol Behav 127:1-7.
    • (2014) Physiol Behav , vol.127 , pp. 1-7
    • Bitsika, V.1    Sharpley, C.F.2    Sweeney, J.A.3    McFarlane, J.R.4
  • 19
    • 0035133609 scopus 로고    scopus 로고
    • Association between-g308a tumor necrosis factor alpha gene polymorphism and schizophrenia
    • Boin F, Zanardini R, Pioli R, Altamura CA, Maes M, Gennarelli M (2001). Association between-G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. Mol Psychiatry 6:79-82.
    • (2001) Mol Psychiatry , vol.6 , pp. 79-82
    • Boin, F.1    Zanardini, R.2    Pioli, R.3    Altamura, C.A.4    Maes, M.5    Gennarelli, M.6
  • 21
    • 79955994712 scopus 로고    scopus 로고
    • Association of fkbp5, comt and chrna5 polymorphisms with ptsd among outpatients at risk for ptsd
    • Boscarino JA, Erlich PM, Hoffman SN, Rukstalis M, Stewart WF (2011). Association of FKBP5, COMT and CHRNA5 polymorphisms with PTSD among outpatients at risk for PTSD. Psychiatry Res 188:173-174.
    • (2011) Psychiatry Res , vol.188 , pp. 173-174
    • Boscarino, J.A.1    Erlich, P.M.2    Hoffman, S.N.3    Rukstalis, M.4    Stewart, W.F.5
  • 22
    • 0034099844 scopus 로고    scopus 로고
    • Comorbidity of psychiatric disorders and posttraumatic stress disorder
    • Brady KT, Killeen TK, Brewerton T, Lucerini S (2000). Comorbidity of psychiatric disorders and posttraumatic stress disorder. J Clin Psychiatry 61 (Suppl 7): 22-32.
    • (2000) J Clin Psychiatry , vol.61 , pp. 22-32
    • Brady, K.T.1    Killeen, T.K.2    Brewerton, T.3    Lucerini, S.4
  • 25
    • 40349116631 scopus 로고    scopus 로고
    • Learning and memory impairment in ptsd: Relationship to depression
    • Burriss L, Ayers E, Ginsberg J, Powell DA (2008). Learning and memory impairment in PTSD: relationship to depression. Depress Anxiety 25:149-157.
    • (2008) Depress Anxiety , vol.25 , pp. 149-157
    • Burriss, L.1    Ayers, E.2    Ginsberg, J.3    Powell, D.A.4
  • 26
    • 84857136589 scopus 로고    scopus 로고
    • Association study between functional polymorphisms in the tnfalpha gene and obsessive-compulsive disorder
    • Cappi C, Muniz RK, Sampaio AS, Cordeiro Q, Brentani H, Palácios SA, et al. (2012). Association study between functional polymorphisms in the TNFalpha gene and obsessive-compulsive disorder. Arq Neuropsiquiatr 70:87-90.
    • (2012) Arq Neuropsiquiatr , vol.70 , pp. 87-90
    • Cappi, C.1    Muniz, R.K.2    Sampaio, A.S.3    Cordeiro, Q.4    Brentani, H.5    Palácios, S.A.6
  • 27
    • 6944229787 scopus 로고    scopus 로고
    • Interleukin 6-174g/c promoter gene polymorphism and sporadic Alzheimer's disease: Geographic allele and genotype variations in Europe
    • Capurso C, Solfrizzi V, D'Introno A, Colacicco AM, Capurso SA, Capurso A, Panza F (2004). Interleukin 6-174G/C promoter gene polymorphism and sporadic Alzheimer's disease: geographic allele and genotype variations in Europe. Exp Gerontol 39:1567-1573.
    • (2004) Exp Gerontol , vol.39 , pp. 1567-1573
    • Capurso, C.1    Solfrizzi, V.2    D'Introno, A.3    Colacicco, A.M.4    Capurso, S.A.5    Capurso, A.6    Panza, F.7
  • 28
    • 84893345725 scopus 로고    scopus 로고
    • Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder
    • Carvalho LA, Bergink V, Sumaski L, Wijkhuijs J, Hoogendijk WJ, Birkenhager TK, Drexhage HA (2014). Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder. Transl Psychiatry 4:e344.
    • (2014) Transl Psychiatry , vol.4 , pp. e344
    • Carvalho, L.A.1    Bergink, V.2    Sumaski, L.3    Wijkhuijs, J.4    Hoogendijk, W.J.5    Birkenhager, T.K.6    Drexhage, H.A.7
  • 29
    • 84872500205 scopus 로고    scopus 로고
    • Candidate genes expression profile associated with antidepressants response in the gendep study: Differentiating between baseline 'predictors' and longitudinal 'targets'
    • Cattaneo A, Gennarelli M, Uher R, Breen G, Farmer A, Aitchison KJ, et al. (2013). Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'. Neuropsychopharmacol 38:377-385.
    • (2013) Neuropsychopharmacol , vol.38 , pp. 377-385
    • Cattaneo, A.1    Gennarelli, M.2    Uher, R.3    Breen, G.4    Farmer, A.5    Aitchison, K.J.6
  • 30
    • 76649086050 scopus 로고    scopus 로고
    • The-308 (g/a) single nucleotide polymorphism in the TNF-Alpha gene and the risk of major depression in the elderly
    • Cerri AP, Arosio B, Viazzoli C, Confalonieri R, Vergani C, Annoni G (2010). The-308 (G/A) single nucleotide polymorphism in the TNF-Alpha gene and the risk of major depression in the elderly. Int J Geriatr Psychiatry 25:219-223.
    • (2010) Int J Geriatr Psychiatry , vol.25 , pp. 219-223
    • Cerri, A.P.1    Arosio, B.2    Viazzoli, C.3    Confalonieri, R.4    Vergani, C.5    Annoni, G.6
  • 31
    • 81255129690 scopus 로고    scopus 로고
    • Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern swedish population
    • Ceulemans S, de Zutter S, Heyrman L, Norrback KF, Nordin A, Nilsson LG, et al. (2011). Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population. Bipolar Disord 13:614-623.
    • (2011) Bipolar Disord , vol.13 , pp. 614-623
    • Ceulemans, S.1    De Zutter, S.2    Heyrman, L.3    Norrback, K.F.4    Nordin, A.5    Nilsson, L.G.6
  • 32
    • 79954568225 scopus 로고    scopus 로고
    • Expression of anti-cardiolipin antibodies and inflammatory associated factors in patients with schizophrenia
    • Chang SH, Chiang SY, Chiu CC, Tsai CC, Tsai HH, Huang CY, et al. (2011). Expression of anti-cardiolipin antibodies and inflammatory associated factors in patients with schizophrenia. Psychiatry Res 187:341-346.
    • (2011) Psychiatry Res , vol.187 , pp. 341-346
    • Chang, S.H.1    Chiang, S.Y.2    Chiu, C.C.3    Tsai, C.C.4    Tsai, H.H.5    Huang, C.Y.6
  • 33
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao CC, Hu S, Molitor TW, Shaskan EG, Peterson PK (1992). Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 149:2736-2741.
    • (1992) J Immunol , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 34
    • 84892691172 scopus 로고    scopus 로고
    • Gut microbiota, low-grade inflammation, and metabolic syndrome
    • Chassaing B, Gewirtz AT (2014). Gut microbiota, low-grade inflammation, and metabolic syndrome. Toxicol Pathol 42:49-53.
    • (2014) Toxicol Pathol , vol.42 , pp. 49-53
    • Chassaing, B.1    Gewirtz, A.T.2
  • 35
    • 69449108280 scopus 로고    scopus 로고
    • Stress and disorders of the stress system
    • Chrousos GP (2009). Stress and disorders of the stress system. Nat Rev Endocrinol 5:374.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 374
    • Chrousos, G.P.1
  • 37
    • 84947505675 scopus 로고    scopus 로고
    • Distinguishing ptsd, complex ptsd, and borderline personality disorder: A latent class analysis
    • Cloitre M, Garvert DW, Weiss B, Carlson EB, Bryant RA (2014). Distinguishing PTSD, complex PTSD, and borderline personality disorder: a latent class analysis. Eur J Psychotraumatol 5. doi: 10.3402/ejpt.v5.25097.
    • (2014) Eur J Psychotraumatol , vol.5
    • Cloitre, M.1    Garvert, D.W.2    Weiss, B.3    Carlson, E.B.4    Bryant, R.A.5
  • 38
    • 80052709724 scopus 로고    scopus 로고
    • The characteristic long-term upregulation of hippocampal nf-?b complex in ptsd-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure
    • Cohen H, Kozlovsky N, Matar MA, Zohar J, Kaplan Z (2011). The characteristic long-term upregulation of hippocampal NF-?B complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposure. Neuropsychopharmacology 36:2286-2302.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2286-2302
    • Cohen, H.1    Kozlovsky, N.2    Matar, M.A.3    Zohar, J.4    Kaplan, Z.5
  • 39
    • 79551694651 scopus 로고    scopus 로고
    • The microbiome-gut-brain axis: From bowel to behavior
    • Cryan JF, O'Mahony SM (2011). The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterol Motil 23:187-192.
    • (2011) Neurogastroenterol Motil , vol.23 , pp. 187-192
    • Cryan, J.F.1    O'Mahony, S.M.2
  • 41
    • 55249121342 scopus 로고    scopus 로고
    • Independent influence of insulin, catecholamines, and thyroid hormones on metabolic syndrome
    • De Pergola G, Giorgino F, Benigno R, Guida P, Giorgino R (2008). Independent influence of insulin, catecholamines, and thyroid hormones on metabolic syndrome. Obesity (Silver Spring) 16:2405-2411.
    • (2008) Obesity (Silver Spring , vol.16 , pp. 2405-2411
    • De Pergola, G.1    Giorgino, F.2    Benigno, R.3    Guida, P.4    Giorgino, R.5
  • 43
    • 79952634079 scopus 로고    scopus 로고
    • Inflammatory gene expression in monocytes of patients with schizophrenia: Overlap and difference with bipolar disorder. A study in naturalistically treated patients
    • Drexhage RC, van der Heul-Nieuwenhuijsen L, Padmos RC, van Beveren N, Cohen D, Versnel MA, et al. (2010). Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patients. Int J Neuropsychopharmacol 13:1369-1381.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 1369-1381
    • Drexhage, R.C.1    Van Der Heul-Nieuwenhuijsen, L.2    Padmos, R.C.3    Van Beveren, N.4    Cohen, D.5    Versnel, M.A.6
  • 44
    • 84883654709 scopus 로고    scopus 로고
    • Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: Findings from the netherlands study of depression and anxiety (nesda
    • Duivis HE, Vogelzangs N, Kupper N, de Jonge P, Penninx BW., 2013). Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: findings from the Netherlands Study of Depression and Anxiety (NESDA). Psychoneuroendocrinology 38:1573-1585.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 1573-1585
    • Duivis, H.E.1    Vogelzangs, N.2    Kupper, N.3    De Jonge, P.4    Penninx, B.W.5
  • 45
    • 52149089191 scopus 로고    scopus 로고
    • Do acute psychological and psychobiological responses to trauma predict subsequent symptom severities of ptsd and depression?
    • Ehring T, Ehlers A, Cleare AJ, Glucksman E (2008). Do acute psychological and psychobiological responses to trauma predict subsequent symptom severities of PTSD and depression? Psychiatry Res 161:67-75.
    • (2008) Psychiatry Res , vol.161 , pp. 67-75
    • Ehring, T.1    Ehlers, A.2    Cleare, A.J.3    Glucksman, E.4
  • 46
    • 36849037934 scopus 로고    scopus 로고
    • Neurohormonal-cytokine interactions: Implications for inflammation, common human diseases and well-being
    • Elenkov IJ (2008). Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem Int 52:40-51.
    • (2008) Neurochem Int , vol.52 , pp. 40-51
    • Elenkov, I.J.1
  • 48
    • 84898653003 scopus 로고    scopus 로고
    • Assessment of plasma c-reactive protein as a biomarker of posttraumatic stress disorder risk
    • Marine Resiliency Study Team
    • Eraly SA, Nievergelt CM, Maihofer AX, Barkauskas DA, Biswas N, Agorastos A, et al., Marine Resiliency Study Team (2014). Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk. JAMA Psychiatry 71:423-431.
    • (2014) JAMA Psychiatry , vol.71 , pp. 423-431
    • Eraly, S.A.1    Nievergelt, C.M.2    Maihofer, A.X.3    Barkauskas, D.A.4    Biswas, N.5    Agorastos, A.6
  • 50
    • 68849099715 scopus 로고    scopus 로고
    • The effects of undertreated chronic medical illnesses in patients with severe mental disorders
    • Fagiolini A, Goracci A (2009). The effects of undertreated chronic medical illnesses in patients with severe mental disorders. J Clin Psychiatry 70 (Suppl 3):22-29.
    • (2009) J Clin Psychiatry , vol.70 , pp. 22-29
    • Fagiolini, A.1    Goracci, A.2
  • 51
    • 0345269140 scopus 로고    scopus 로고
    • Interleukin-6-174g/c promoter gene polymorphism c allele reduces Alzheimer's disease risk
    • Faltraco F, Bürger K, Zill P, Teipel SJ, Möller H-J, Hampel H, et al. (2003). Interleukin-6-174G/C promoter gene polymorphism c allele reduces Alzheimer's disease risk. J Am Geriatr Soc 51:578-579.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 578-579
    • Faltraco, F.1    Bürger, K.2    Zill, P.3    Teipel, S.J.4    Möller, H.-J.5    Hampel, H.6
  • 55
    • 0033660004 scopus 로고    scopus 로고
    • Association between c-reactive protein and features of the metabolic syndrome: A population-based study
    • Fröhlich M, Imhof A, Berg G, Hutchinson WL, Pepys MB, Boeing H, et al. (2000). Association between C-reactive protein and features of the metabolic syndrome: a population-based study. Diabetes Care 23:1835-1839.
    • (2000) Diabetes Care , vol.23 , pp. 1835-1839
    • Fröhlich, M.1    Imhof, A.2    Berg, G.3    Hutchinson, W.L.4    Pepys, M.B.5    Boeing, H.6
  • 56
    • 84939425648 scopus 로고    scopus 로고
    • Neuroinflammatory pathways in anxiety, posttraumatic stress, and obsessive compulsive disorders
    • Furtado M, Katzman MA (2015). Neuroinflammatory pathways in anxiety, posttraumatic stress, and obsessive compulsive disorders. Psychiatry Res 229:37-48.
    • (2015) Psychiatry Res , vol.229 , pp. 37-48
    • Furtado, M.1    Katzman, M.A.2
  • 58
    • 84959333739 scopus 로고    scopus 로고
    • Innate immune receptor toll-like receptor 4 signalling in neuropsychiatric diseases
    • García Bueno B, Caso JR, Madrigal JL, Leza JC (2016). Innate immune receptor toll-like receptor 4 signalling in neuropsychiatric diseases. Neurosci Biobehav Rev 64:134-147.
    • (2016) Neurosci Biobehav Rev , vol.64 , pp. 134-147
    • García Bueno, B.1    Caso, J.R.2    Madrigal, J.L.3    Leza, J.C.4
  • 59
    • 84882969528 scopus 로고    scopus 로고
    • Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease
    • Gardai SJ, Mao W, Schüle B, Babcock M, Schoebel S, Lorenzana C, et al. (2013). Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease. PLoS One 8:e71634.
    • (2013) PLoS One , vol.8 , pp. e71634
    • Gardai, S.J.1    Mao, W.2    Schüle, B.3    Babcock, M.4    Schoebel, S.5    Lorenzana, C.6
  • 61
    • 63249106013 scopus 로고    scopus 로고
    • Associations of c-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the whitehall II study
    • Gimeno D, Kivimäki M, Brunner EJ, Elovainio M, de Vogli R, Steptoe A, et al. (2009). Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study. Psychol Med 39:413-423.
    • (2009) Psychol Med , vol.39 , pp. 413-423
    • Gimeno, D.1    Kivimäki, M.2    Brunner, E.J.3    Elovainio, M.4    De Vogli, R.5    Steptoe, A.6
  • 62
    • 77952102565 scopus 로고    scopus 로고
    • Comorbidity of posttraumatic stress disorder, anxiety and depression: A 20-year longitudinal study of war veterans
    • Ginzburg K, Ein-Dor T, Solomon Z (2010). Comorbidity of posttraumatic stress disorder, anxiety and depression: a 20-year longitudinal study of war veterans. J Affect Disord 123:249-257.
    • (2010) J Affect Disord , vol.123 , pp. 249-257
    • Ginzburg, K.1    Ein-Dor, T.2    Solomon, Z.3
  • 63
    • 84878262069 scopus 로고    scopus 로고
    • Blood-based gene-expression predictors of ptsd risk and resilience among deployed marines: A pilot study
    • Marine Resiliency Study Investigators
    • Glatt SJ, Tylee DS, Chandler SD, Pazol J, Nievergelt CM, Woelk CH, et al., Marine Resiliency Study Investigators (2013). Blood-based gene-expression predictors of PTSD risk and resilience among deployed marines: a pilot study. Am J Med Genet B Neuropsychiatr Genet 162B:313-326.
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162 B , pp. 313-326
    • Glatt, S.J.1    Tylee, D.S.2    Chandler, S.D.3    Pazol, J.4    Nievergelt, C.M.5    Woelk, C.H.6
  • 64
    • 84907033667 scopus 로고    scopus 로고
    • Reduced peripheral expression of the glucocorticoid receptor a isoform in individuals with posttraumatic stress disorder: A cumulative effect of trauma burden
    • Gola H, Engler A, Morath J, Adenauer H, Elbert T, Kolassa IT, Engler H (2014). Reduced peripheral expression of the glucocorticoid receptor a isoform in individuals with posttraumatic stress disorder: a cumulative effect of trauma burden. PLoS One 9:e86333.
    • (2014) PLoS One , vol.9 , pp. e86333
    • Gola, H.1    Engler, A.2    Morath, J.3    Adenauer, H.4    Elbert, T.5    Kolassa, I.T.6    Engler, H.7
  • 65
    • 0037322334 scopus 로고    scopus 로고
    • Flow cytometric determination of glucocorticoid receptor (gcr expression in lymphocyte subpopulations: Lower quantity of gcr in patients with post-traumatic stress disorder (ptsd)
    • Gotovac K, Sabioncello A, Rabatic S, Berki T, Dekaris D (2003). Flow cytometric determination of glucocorticoid receptor (GCR) expression in lymphocyte subpopulations: lower quantity of GCR in patients with post-traumatic stress disorder (PTSD). Clin Exp Immunol 131:335-339.
    • (2003) Clin Exp Immunol , vol.131 , pp. 335-339
    • Gotovac, K.1    Sabioncello, A.2    Rabatic, S.3    Berki, T.4    Dekaris, D.5
  • 66
    • 77949417517 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as therapeutic targets for cognitive disorders
    • Gravius A, Pietraszek M, Dekundy A, Danysz W (2010). Metabotropic glutamate receptors as therapeutic targets for cognitive disorders. Curr Top Med Chem 10:187-206.
    • (2010) Curr Top Med Chem , vol.10 , pp. 187-206
    • Gravius, A.1    Pietraszek, M.2    Dekundy, A.3    Danysz, W.4
  • 67
    • 0032852971 scopus 로고    scopus 로고
    • Catecholamines in depression: A cumulative study of urinary norepinephrine and its major metabolites in unipolar and bipolar depressed patients versus healthy volunteers at the nimh
    • Grossman F, Potter WZ (1999). Catecholamines in depression: a cumulative study of urinary norepinephrine and its major metabolites in unipolar and bipolar depressed patients versus healthy volunteers at the NIMH. Psychiatry Res 87:21-27.
    • (1999) Psychiatry Res , vol.87 , pp. 21-27
    • Grossman, F.1    Potter, W.Z.2
  • 68
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/national heart, lung, and blood institute scientific statement
    • Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. (2005). Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112:2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4    Eckel, R.H.5    Franklin, B.A.6
  • 69
    • 84952660547 scopus 로고    scopus 로고
    • Altered gene expression of the innate immune, neuroendocrine, and nuclear factor-kappa b (nf-?b) systems is associated with posttraumatic stress disorder in military personnel
    • Guardado P, Olivera A, Rusch HL, Roy M, Martin C, Lejbman N, et al. (2016). Altered gene expression of the innate immune, neuroendocrine, and nuclear factor-kappa B (NF-?B) systems is associated with posttraumatic stress disorder in military personnel. J Anxiety Disord 38:9-20.
    • (2016) J Anxiety Disord , vol.38 , pp. 9-20
    • Guardado, P.1    Olivera, A.2    Rusch, H.L.3    Roy, M.4    Martin, C.5    Lejbman, N.6
  • 70
    • 84155168053 scopus 로고    scopus 로고
    • Association of TNF-A promoter gene g-308 a polymorphism with metabolic syndrome, insulin resistance, serum TNF-A and leptin levels in indian adult women
    • Gupta V, Gupta A, Jafar T, Gupta V, Agrawal S, Srivastava N, et al. (2012). Association of TNF-A promoter gene G-308 A polymorphism with metabolic syndrome, insulin resistance, serum TNF-A and leptin levels in Indian adult women. Cytokine 57:32-36.
    • (2012) Cytokine , vol.57 , pp. 32-36
    • Gupta, V.1    Gupta, A.2    Jafar, T.3    Gupta, V.4    Agrawal, S.5    Srivastava, N.6
  • 71
    • 84896719598 scopus 로고    scopus 로고
    • Relationship between clinical features and inflammation-related monocyte gene expression in bipolar disorder-towards a better understanding of psychoimmunological interactions
    • Haarman BC, Riemersma-Van der Lek RF, Burger H, Netkova M, Drexhage RC, Bootsman F, et al. (2014). Relationship between clinical features and inflammation-related monocyte gene expression in bipolar disorder-towards a better understanding of psychoimmunological interactions. Bipolar Disord 16:137-150.
    • (2014) Bipolar Disord , vol.16 , pp. 137-150
    • Haarman, B.C.1    Riemersma-Van Der Lek, R.F.2    Burger, H.3    Netkova, M.4    Drexhage, R.C.5    Bootsman, F.6
  • 73
    • 0033134682 scopus 로고    scopus 로고
    • Associations of elevated interleukin-6 and c-reactive protein levels with mortality in the elderly
    • Harris TB, Ferrucci L, Tracy RP, Corti MC, Wacholder S, Ettinger WH Jr., et al. (1999). Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med 106:506-512.
    • (1999) Am J Med , vol.106 , pp. 506-512
    • Harris, T.B.1    Ferrucci, L.2    Tracy, R.P.3    Corti, M.C.4    Wacholder, S.5    Ettinger, W.H.6
  • 74
    • 79953232321 scopus 로고    scopus 로고
    • Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy
    • Hauer D, Weis F, Papassotiropoulos A, Schmoeckel M, Beiras-Fernandez A, Lieke J, et al. (2011). Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy. Crit Care Med 39:643-650.
    • (2011) Crit Care Med , vol.39 , pp. 643-650
    • Hauer, D.1    Weis, F.2    Papassotiropoulos, A.3    Schmoeckel, M.4    Beiras-Fernandez, A.5    Lieke, J.6
  • 75
    • 61649113529 scopus 로고    scopus 로고
    • The association of posttraumatic stress disorder and metabolic syndrome: A study of increased health risk in veterans
    • Heppner PS, Crawford EF, Haji UA, Afari N, Hauger RL, Dashevsky BA, et al. (2009). The association of posttraumatic stress disorder and metabolic syndrome: a study of increased health risk in veterans. BMC Med 7:1.
    • (2009) BMC Med , vol.7 , pp. 1
    • Heppner, P.S.1    Crawford, E.F.2    Haji, U.A.3    Afari, N.4    Hauger, R.L.5    Dashevsky, B.A.6
  • 76
    • 0344012614 scopus 로고    scopus 로고
    • Putting the brake on inflammatory responses: The role of glucocorticoids
    • Hermoso MA, Cidlowski JA (2003). Putting the brake on inflammatory responses: the role of glucocorticoids. IUBMB Life 55:497-504.
    • (2003) IUBMB Life , vol.55 , pp. 497-504
    • Hermoso, M.A.1    Cidlowski, J.A.2
  • 77
    • 84922777769 scopus 로고    scopus 로고
    • A shift toward t helper 2 responses and an increase in modulators of innate immunity in depressed patients treated with escitalopram
    • Ho PS, Yeh YW, Huang SY, Liang CS (2015). A shift toward T helper 2 responses and an increase in modulators of innate immunity in depressed patients treated with escitalopram. Psychoneuroendocrinology 53:246-255.
    • (2015) Psychoneuroendocrinology , vol.53 , pp. 246-255
    • Ho, P.S.1    Yeh, Y.W.2    Huang, S.Y.3    Liang, C.S.4
  • 78
    • 84923011930 scopus 로고    scopus 로고
    • Pharmacotherapy for post-traumatic stress disorder: Systematic review and meta-Analysis
    • Hoskins M, Pearce J, Bethell A, Dankova L, Barbui C, Tol WA, et al. (2015). Pharmacotherapy for post-traumatic stress disorder: systematic review and meta-Analysis. Br J Psychiatry 206:93-100.
    • (2015) Br J Psychiatry , vol.206 , pp. 93-100
    • Hoskins, M.1    Pearce, J.2    Bethell, A.3    Dankova, L.4    Barbui, C.5    Tol, W.A.6
  • 80
    • 84908221749 scopus 로고    scopus 로고
    • Association between toll-like receptors expression and major depressive disorder
    • Hung YY, Kang HY, Huang KW, Huang TL (2014). Association between toll-like receptors expression and major depressive disorder. Psychiatry Res 220:283-286.
    • (2014) Psychiatry Res , vol.220 , pp. 283-286
    • Hung, Y.Y.1    Kang, H.Y.2    Huang, K.W.3    Huang, T.L.4
  • 81
    • 72949116123 scopus 로고    scopus 로고
    • Interleukin-1 beta-511c/t genetic polymorphism is associated with age of onset of geriatric depression
    • Hwang JP, Tsai SJ, Hong CJ, Yang CH, Hsu CD, Liou YJ (2009). Interleukin-1 beta-511C/T genetic polymorphism is associated with age of onset of geriatric depression. Neuromolecular Med 11:322-327.
    • (2009) Neuromolecular Med , vol.11 , pp. 322-327
    • Hwang, J.P.1    Tsai, S.J.2    Hong, C.J.3    Yang, C.H.4    Hsu, C.D.5    Liou, Y.J.6
  • 82
    • 84885796652 scopus 로고    scopus 로고
    • Dysregulation of leukocyte gene expression in women with medicationrefractory depression versus healthy non-depressed controls
    • Iacob E, Light KC, Tadler SC, Weeks HR, White AT, Hughen RW, et al. (2013). Dysregulation of leukocyte gene expression in women with medicationrefractory depression versus healthy non-depressed controls. BMC Psychiatry 13:273.
    • (2013) BMC Psychiatry , vol.13 , pp. 273
    • Iacob, E.1    Light, K.C.2    Tadler, S.C.3    Weeks, H.R.4    White, A.T.5    Hughen, R.W.6
  • 83
    • 45149115075 scopus 로고    scopus 로고
    • Inflammatory markers in relation to insulin resistance and the metabolic syndrome
    • Ingelsson E, Hulthe J, Lind L (2008). Inflammatory markers in relation to insulin resistance and the metabolic syndrome. Eur J Clin Invest 38:502-509.
    • (2008) Eur J Clin Invest , vol.38 , pp. 502-509
    • Ingelsson, E.1    Hulthe, J.2    Lind, L.3
  • 84
    • 84924559946 scopus 로고    scopus 로고
    • Low il-8 is associated with anxiety in suicidal patients: Genetic variation and decreased protein levels
    • Janelidze S, Suchankova P, Ekman A, Erhardt S, Sellgren C, Samuelsson M, et al. (2015). Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels. Acta Psychiatr Scand 131:269-278.
    • (2015) Acta Psychiatr Scand , vol.131 , pp. 269-278
    • Janelidze, S.1    Suchankova, P.2    Ekman, A.3    Erhardt, S.4    Sellgren, C.5    Samuelsson, M.6
  • 86
    • 84910660983 scopus 로고    scopus 로고
    • Early-life stress and hpa axis trigger recurrent adulthood depression
    • Juruena MF (2014). Early-life stress and HPA axis trigger recurrent adulthood depression. Epilepsy Behav 38:148-159.
    • (2014) Epilepsy Behav , vol.38 , pp. 148-159
    • Juruena, M.F.1
  • 87
    • 0036079118 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor-Alpha and interferon-gamma mRNA in blood cells correlates with depression scores during an acute attack in patients with multiple sclerosis
    • Kahl KG, Kruse N, Faller H, Weiss H, Rieckmann P (2002). Expression of tumor necrosis factor-Alpha and interferon-gamma mRNA in blood cells correlates with depression scores during an acute attack in patients with multiple sclerosis. Psychoneuroendocrinology 27:671-681.
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 671-681
    • Kahl, K.G.1    Kruse, N.2    Faller, H.3    Weiss, H.4    Rieckmann, P.5
  • 88
    • 84880752699 scopus 로고    scopus 로고
    • Association between genetic polymorphisms of toll-like receptor 2 (tlr2) and schizophrenia in the Korean population
    • Kang WS, Park JK, Lee SM, Kim SK, Park HJ, Kim JW (2013). Association between genetic polymorphisms of toll-like receptor 2 (TLR2) and schizophrenia in the Korean population. Gene 526:182-186.
    • (2013) Gene , vol.526 , pp. 182-186
    • Kang, W.S.1    Park, J.K.2    Lee, S.M.3    Kim, S.K.4    Park, H.J.5    Kim, J.W.6
  • 91
    • 84862894687 scopus 로고    scopus 로고
    • Roles of interferongamma and its target genes in schizophrenia: Proteomics-based reverse genetics from mouse to human
    • Kim HJ, Eom CY, Kwon J, Joo J, Lee S, Nah SS, et al. (2012a). Roles of interferongamma and its target genes in schizophrenia: Proteomics-based reverse genetics from mouse to human. Proteomics 12:1815-1829.
    • (2012) Proteomics , vol.12 , pp. 1815-1829
    • Kim, H.J.1    Eom, C.Y.2    Kwon, J.3    Joo, J.4    Lee, S.5    Nah, S.S.6
  • 93
    • 70449525199 scopus 로고    scopus 로고
    • Immune and nervous systems: More than just a superficial similarity?
    • Kioussis D, Pachnis V (2009). Immune and nervous systems: more than just a superficial similarity? Immunity 31:705-710.
    • (2009) Immunity , vol.31 , pp. 705-710
    • Kioussis, D.1    Pachnis, V.2
  • 94
    • 32844458680 scopus 로고    scopus 로고
    • Polymorphisms in fkbp5 are associated with peritraumatic dissociation in medically injured children
    • Koenen KC, Saxe G, Purcell S, Smoller JW, Bartholomew D, Miller A, et al. (2005). Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children. Mol Psychiatry 10:1058-1059.
    • (2005) Mol Psychiatry , vol.10 , pp. 1058-1059
    • Koenen, K.C.1    Saxe, G.2    Purcell, S.3    Smoller, J.W.4    Bartholomew, D.5    Miller, A.6
  • 95
    • 36849012474 scopus 로고    scopus 로고
    • Common genetic liability to major depression and posttraumatic stress disorder in men
    • Koenen KC, Fu QJ, Ertel K, Lyons MJ, Eisen SA, True WR, et al. (2008). Common genetic liability to major depression and posttraumatic stress disorder in men. J Affect Disord 105:109-115.
    • (2008) J Affect Disord , vol.105 , pp. 109-115
    • Koenen, K.C.1    Fu, Q.J.2    Ertel, K.3    Lyons, M.J.4    Eisen, S.A.5    True, W.R.6
  • 99
    • 43249125787 scopus 로고    scopus 로고
    • Glucocorticoid receptor gene polymorphisms in premenopausal women with major depression
    • (Premenopausal Osteoporosis Women Alendronate Depression Study Group
    • Krishnamurthy P, Romagni P, Torvik S, Gold PW, Charney DS, Detera-Wadleigh S, Cizza G, P.O.W.E.R. (Premenopausal, Osteoporosis Women, Alendronate, Depression) Study Group (2008). Glucocorticoid receptor gene polymorphisms in premenopausal women with major depression. Horm Metab Res 40:194-198.
    • (2008) Horm Metab Res , vol.40 , pp. 194-198
    • Krishnamurthy, P.1    Romagni, P.2    Torvik, S.3    Gold, P.W.4    Charney, D.S.5    Detera-Wadleigh, S.6    Cizza, G.P.O.W.E.R.7
  • 100
    • 79960132943 scopus 로고    scopus 로고
    • Cytokine release from innate immune cells: Association with diverse membrane trafficking pathways
    • Lacy P, Stow JL (2011). Cytokine release from innate immune cells: association with diverse membrane trafficking pathways. Blood 118:9-18.
    • (2011) Blood , vol.118 , pp. 9-18
    • Lacy, P.1    Stow, J.L.2
  • 101
    • 84907172346 scopus 로고    scopus 로고
    • Metabolic syndrome and inflammation markers in patients with schizophrenia and recurrent depressive disorder
    • Lasic D, Bevanda M, Bošnjak N, Uglešic B, Glavina T, Franic T (2014). Metabolic syndrome and inflammation markers in patients with schizophrenia and recurrent depressive disorder. Psychiatr Danub 26:214-219.
    • (2014) Psychiatr Danub , vol.26 , pp. 214-219
    • Lasic, D.1    Bevanda, M.2    Bošnjak, N.3    Uglešic, B.4    Glavina, T.5    Franic, T.6
  • 102
    • 77955550908 scopus 로고    scopus 로고
    • Variations in fkbp5 and bdnf genes are suggestively associated with depression in a swedish population-based cohort
    • Lavebratt C, Aberg E, Sjöholm LK, Forsell Y (2010). Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort. J Affect Disord 125:249-255.
    • (2010) J Affect Disord , vol.125 , pp. 249-255
    • Lavebratt, C.1    Aberg, E.2    Sjöholm, L.K.3    Forsell, Y.4
  • 103
    • 84887223481 scopus 로고    scopus 로고
    • Association among clinical response, hippocampal volume, and fkbp5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy
    • Levy-Gigi E, Szabó C, Kelemen O, Kéri S (2013). Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy. Biol Psychiatry 74:793-800.
    • (2013) Biol Psychiatry , vol.74 , pp. 793-800
    • Levy-Gigi, E.1    Szabó, C.2    Kelemen, O.3    Kéri, S.4
  • 104
    • 70350142744 scopus 로고    scopus 로고
    • Borderline personality or complex posttraumatic stress disorder? An update on the controversy
    • Lewis KL, Grenyer BFS (2009). Borderline Personality or Complex Posttraumatic Stress Disorder? An Update on the Controversy. Harv Rev Psychiatry 17:322-328.
    • (2009) Harv Rev Psychiatry , vol.17 , pp. 322-328
    • Lewis, K.L.1    Grenyer, B.F.S.2
  • 105
    • 0037336701 scopus 로고    scopus 로고
    • Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-mapk pathway
    • Li Y, Liu L, Barger SW, Griffin WS (2003). Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci 23:1605-1611.
    • (2003) J Neurosci , vol.23 , pp. 1605-1611
    • Li, Y.1    Liu, L.2    Barger, S.W.3    Griffin, W.S.4
  • 106
    • 84905829378 scopus 로고    scopus 로고
    • The relationship between glucocorticoid receptor polymorphisms, stressful life events, social support, and post-traumatic stress disorder
    • Lian Y, Xiao J, Wang Q, Ning L, Guan S, Ge H, et al. (2014). The relationship between glucocorticoid receptor polymorphisms, stressful life events, social support, and post-traumatic stress disorder. BMC Psychiatry 14:232.
    • (2014) BMC Psychiatry , vol.14 , pp. 232
    • Lian, Y.1    Xiao, J.2    Wang, Q.3    Ning, L.4    Guan, S.5    Ge, H.6
  • 107
    • 0344359767 scopus 로고    scopus 로고
    • Differential regulation of hippocampal glucocorticoid receptors mRNA and fast feedback: Relevance to post-traumatic stress disorder
    • Liberzon I, López JF, Flagel SB, Vázquez DM, Young EA (1999). Differential regulation of hippocampal glucocorticoid receptors mRNA and fast feedback: relevance to post-traumatic stress disorder. J Neuroendocrinol 11:11-17.
    • (1999) J Neuroendocrinol , vol.11 , pp. 11-17
    • Liberzon, I.1    López, J.F.2    Flagel, S.B.3    Vázquez, D.M.4    Young, E.A.5
  • 108
    • 0043092123 scopus 로고    scopus 로고
    • Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain
    • Licastro F, Grimaldi LM, Bonafé M, Martina C, Olivieri F, Cavallone L, et al. (2003). Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging 24:921-926.
    • (2003) Neurobiol Aging , vol.24 , pp. 921-926
    • Licastro, F.1    Grimaldi, L.M.2    Bonafé, M.3    Martina, C.4    Olivieri, F.5    Cavallone, L.6
  • 110
    • 0037215645 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • Liu B, Hong JS (2003). Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 304:1-7.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.S.2
  • 112
    • 84952941289 scopus 로고    scopus 로고
    • Elevated serum complement factors 3 and 4 are strong inflammatory markers of the metabolic syndrome development: A longitudinal cohort study
    • Liu Z, Tang Q, Wen J, Tang Y, Huang D, Huang Y, et al. (2016). Elevated serum complement factors 3 and 4 are strong inflammatory markers of the metabolic syndrome development: a longitudinal cohort study. Sci Rep 6:18713.
    • (2016) Sci Rep , vol.6 , pp. 18713
    • Liu, Z.1    Tang, Q.2    Wen, J.3    Tang, Y.4    Huang, D.5    Huang, Y.6
  • 113
    • 84881161107 scopus 로고    scopus 로고
    • A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (rora) gene as a significant risk locus
    • Logue MW, Baldwin C, Guffanti G, Melista E, Wolf EJ, Reardon AF, et al. (2013). A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. Mol Psychiatry 18:937-942.
    • (2013) Mol Psychiatry , vol.18 , pp. 937-942
    • Logue, M.W.1    Baldwin, C.2    Guffanti, G.3    Melista, E.4    Wolf, E.J.5    Reardon, A.F.6
  • 114
    • 84878240907 scopus 로고    scopus 로고
    • The influence of metabolic syndrome, physical activity and genotype on catechol-o-methyl transferase promoter-region methylation in schizophrenia
    • Lott SA, Burghardt PR, Burghardt KJ, Bly MJ, Grove TB, Ellingrod VL (2013). The influence of metabolic syndrome, physical activity and genotype on catechol-O-methyl transferase promoter-region methylation in schizophrenia. Pharmacogenomics J 13:264-271.
    • (2013) Pharmacogenomics J , vol.13 , pp. 264-271
    • Lott, S.A.1    Burghardt, P.R.2    Burghardt, K.J.3    Bly, M.J.4    Grove, T.B.5    Ellingrod, V.L.6
  • 115
    • 0033876817 scopus 로고    scopus 로고
    • Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia
    • Luterman JD, Haroutunian V, Yemul S, Ho L, Purohit D, Aisen PS, et al. (2000). Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Arch Neurol 57:1153-1160.
    • (2000) Arch Neurol , vol.57 , pp. 1153-1160
    • Luterman, J.D.1    Haroutunian, V.2    Yemul, S.3    Ho, L.4    Purohit, D.5    Aisen, P.S.6
  • 117
    • 34548849117 scopus 로고    scopus 로고
    • The role of complement in inflammatory diseases from behind the scenes into the spotlight
    • Markiewski MM, Lambris JD (2007). The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am J Pathol 171:715-727.
    • (2007) Am J Pathol , vol.171 , pp. 715-727
    • Markiewski, M.M.1    Lambris, J.D.2
  • 118
    • 84873550690 scopus 로고    scopus 로고
    • Lymphocyte glucocorticoid receptor expression level and hormonebinding properties differ between war trauma-exposed men with and without ptsd
    • Matic G, Milutinovic DV, Nestorov J, Elakovic I, Jovanovic SM, Perišic T, et al. (2013). Lymphocyte glucocorticoid receptor expression level and hormonebinding properties differ between war trauma-exposed men with and without PTSD. Prog Neuropsychopharmacol Biol Psychiatry 43:238-245.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.43 , pp. 238-245
    • Matic, G.1    Milutinovic, D.V.2    Nestorov, J.3    Elakovic, I.4    Jovanovic, S.M.5    Perišic, T.6
  • 120
    • 0036752591 scopus 로고    scopus 로고
    • Sex, stress and the hippocampus: Allostasis, allostatic load and the aging process
    • McEwen BS (2002). Sex, stress and the hippocampus: allostasis, allostatic load and the aging process. Neurobiol Aging 23:921-939.
    • (2002) Neurobiol Aging , vol.23 , pp. 921-939
    • McEwen, B.S.1
  • 121
    • 11144249792 scopus 로고    scopus 로고
    • Physiological functions for brain nf-kappab
    • Meffert MK, Baltimore D (2005). Physiological functions for brain NF-kappaB. Trends Neurosci 28:37-43.
    • (2005) Trends Neurosci , vol.28 , pp. 37-43
    • Meffert, M.K.1    Baltimore, D.2
  • 122
    • 80051926419 scopus 로고    scopus 로고
    • Using polymorphisms in fkbp5 to define biologically distinct subtypes of posttraumatic stress disorder: Evidence from endocrine and gene expression studies
    • Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, et al. (2011). Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Arch Gen Psychiatry 68:901-910.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 901-910
    • Mehta, D.1    Gonik, M.2    Klengel, T.3    Rex-Haffner, M.4    Menke, A.5    Rubel, J.6
  • 123
    • 84880538825 scopus 로고    scopus 로고
    • Genetic and epigenetic associations of maoa and nr3c1 with depression and childhood adversities
    • Melas PA, Wei Y, Wong CC, Sjöholm LK, Aberg E, Mill J, et al. (2013). Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. Int J Neuropsychopharmacol 16:1513-1528.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 1513-1528
    • Melas, P.A.1    Wei, Y.2    Wong, C.C.3    Sjöholm, L.K.4    Aberg, E.5    Mill, J.6
  • 124
    • 84875812508 scopus 로고    scopus 로고
    • Genetic variation in fkbp5 associated with the extent of stress hormone dysregulation in major depression
    • Menke A, Klengel T, Rubel J, Brückl T, Pfister H, Lucae S, et al. (2013). Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression. Genes Brain Behav 12:289-296.
    • (2013) Genes Brain Behav , vol.12 , pp. 289-296
    • Menke, A.1    Klengel, T.2    Rubel, J.3    Brückl, T.4    Pfister, H.5    Lucae, S.6
  • 125
    • 84942098239 scopus 로고    scopus 로고
    • Cytokine gene variations associated with trait and state anxiety in oncology patients and their family caregivers
    • Miaskowski C, Cataldo JK, Baggott CR, West C, Dunn LB, Dhruva A, et al. (2015). Cytokine gene variations associated with trait and state anxiety in oncology patients and their family caregivers. Support Care Cancer 23:953-965.
    • (2015) Support Care Cancer , vol.23 , pp. 953-965
    • Miaskowski, C.1    Cataldo, J.K.2    Baggott, C.R.3    West, C.4    Dunn, L.B.5    Dhruva, A.6
  • 126
    • 84961290737 scopus 로고    scopus 로고
    • Association of crp genetic variation and crp level with elevated ptsd symptoms and physiological responses in a civilian population with high levels of trauma
    • Michopoulos V, Rothbaum AO, Jovanovic T, Almli LM, Bradley B, Rothbaum BO, et al. (2015). Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma. Am J Psychiatry 172:353-362.
    • (2015) Am J Psychiatry , vol.172 , pp. 353-362
    • Michopoulos, V.1    Rothbaum, A.O.2    Jovanovic, T.3    Almli, L.M.4    Bradley, B.5    Rothbaum, B.O.6
  • 127
    • 84889879076 scopus 로고    scopus 로고
    • Role of allelic variants of fk506-binding protein 51 (fkbp5) gene in the development of anxiety disorders
    • Minelli A, Maffioletti E, Cloninger CR, Magri C, Sartori R, Bortolomasi M, et al. (2013). Role of allelic variants of FK506-binding protein 51 (FKBP5) gene in the development of anxiety disorders. Depress Anxiety 30:1170-1176.
    • (2013) Depress Anxiety , vol.30 , pp. 1170-1176
    • Minelli, A.1    Maffioletti, E.2    Cloninger, C.R.3    Magri, C.4    Sartori, R.5    Bortolomasi, M.6
  • 128
    • 84936891331 scopus 로고    scopus 로고
    • Cytokine and growth factor profiling in patients with the metabolic syndrome
    • Mirhafez SR, Pasdar A, Avan A, Esmaily H, Moezzi A, Mohebati M, et al. (2015). Cytokine and growth factor profiling in patients with the metabolic syndrome. Br J Nutr 113:1911-1919.
    • (2015) Br J Nutr , vol.113 , pp. 1911-1919
    • Mirhafez, S.R.1    Pasdar, A.2    Avan, A.3    Esmaily, H.4    Moezzi, A.5    Mohebati, M.6
  • 129
    • 77955131100 scopus 로고    scopus 로고
    • Mending the broken brain: Neuroimmune interactions in neurogenesis
    • Molina-Holgado E, Molina-Holgado F (2010). Mending the broken brain: neuroimmune interactions in neurogenesis. J Neurochem 114:1277-1290.
    • (2010) J Neurochem , vol.114 , pp. 1277-1290
    • Molina-Holgado, E.1    Molina-Holgado, F.2
  • 130
    • 79959669857 scopus 로고    scopus 로고
    • Expression profiles of cytokines in the brains of Alzheimer's disease (ad) patients compared to the brains of non-demented patients with and without increasing ad pathology
    • Morimoto K, Horio J, Satoh H, Sue L, Beach T, Arita S, et al. (2011). Expression profiles of cytokines in the brains of Alzheimer's disease (AD) patients compared to the brains of non-demented patients with and without increasing AD pathology. J Alzheimers Dis 25:59-76.
    • (2011) J Alzheimers Dis , vol.25 , pp. 59-76
    • Morimoto, K.1    Horio, J.2    Satoh, H.3    Sue, L.4    Beach, T.5    Arita, S.6
  • 131
    • 84927176211 scopus 로고    scopus 로고
    • Type i interferon signaling genes in recurrent major depression: Increased expression detected by whole-blood RNA sequencing
    • Mostafavi S, Battle A, Zhu X, Potash JB,Weissman MM, Shi J, et al. (2014). Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing. Mol Psychiatry 19:1267-1274.
    • (2014) Mol Psychiatry , vol.19 , pp. 1267-1274
    • Mostafavi, S.1    Battle, A.2    Zhu, X.3    Potash Jbweissman, M.M.4    Shi, J.5
  • 132
    • 84900542451 scopus 로고    scopus 로고
    • Metabolic features of the cell danger response
    • Naviaux RK (2014). Metabolic features of the cell danger response. Mitochondrion 16:7-17.
    • (2014) Mitochondrion , vol.16 , pp. 7-17
    • Naviaux, R.K.1
  • 134
    • 50849139232 scopus 로고    scopus 로고
    • Oxidative stress in psychiatric disorders: Evidence base and therapeutic implications
    • Ng F, Berk M, Dean O, Bush AI (2008). Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. Int J Neuropsychopharmacol 11:851-876.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 851-876
    • Ng, F.1    Berk, M.2    Dean, O.3    Bush, A.I.4
  • 136
    • 79955082686 scopus 로고    scopus 로고
    • Transcriptional control of monocyte gene expression in post-traumatic stress disorder
    • O'Donovan A, Sun B, Cole S, Rempel H, Lenoci M, Pulliam L, Neylan T (2011). Transcriptional control of monocyte gene expression in post-traumatic stress disorder. Dis Markers 30:123-132.
    • (2011) Dis Markers , vol.30 , pp. 123-132
    • O'Donovan, A.1    Sun, B.2    Cole, S.3    Rempel, H.4    Lenoci, M.5    Pulliam, L.6    Neylan, T.7
  • 138
    • 82655180649 scopus 로고    scopus 로고
    • Circulating levels of il-18 are significantly influenced by the il-18 + 183 a/g polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: An observational study
    • Opstad TB, Pettersen AA, Arnesen H, Seljeflot I (2011). Circulating levels of IL-18 are significantly influenced by the IL-18 + 183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study. Cardiovasc Diabetol 10:110.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 110
    • Opstad, T.B.1    Pettersen, A.A.2    Arnesen, H.3    Seljeflot, I.4
  • 139
    • 9444238527 scopus 로고    scopus 로고
    • Posttraumatic stress disorder in patients with bipolar disorder: A review of prevalence, correlates, and treatment strategies
    • Otto MW, Perlman CA, Wernicke R, Reese HE, Bauer MS, Pollack MH (2004). Posttraumatic stress disorder in patients with bipolar disorder: a review of prevalence, correlates, and treatment strategies. Bipolar Disord 6:470-479.
    • (2004) Bipolar Disord , vol.6 , pp. 470-479
    • Otto, M.W.1    Perlman, C.A.2    Wernicke, R.3    Reese, H.E.4    Bauer, M.S.5    Pollack, M.H.6
  • 140
    • 84872839404 scopus 로고    scopus 로고
    • The many faces of pleiotropy
    • Paaby AB, Rockman MV (2013). The many faces of pleiotropy. Trends Genet 29:66-73.
    • (2013) Trends Genet , vol.29 , pp. 66-73
    • Paaby, A.B.1    Rockman, M.V.2
  • 141
    • 42049092538 scopus 로고    scopus 로고
    • A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
    • Padmos RC, Hillegers MH, Knijff EM, Vonk R, Bouvy A, Staal FJ, et al. (2008). A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry 65:395-407.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 395-407
    • Padmos, R.C.1    Hillegers, M.H.2    Knijff, E.M.3    Vonk, R.4    Bouvy, A.5    Staal, F.J.6
  • 142
    • 84862111274 scopus 로고    scopus 로고
    • Bidirectional association between depression and metabolic syndrome: A systematic review and meta-Analysis of epidemiological studies
    • Pan A, Keum N, Okereke OI, Sun Q, Kivimaki M, Rubin RR, Hu FB (2012). Bidirectional association between depression and metabolic syndrome: a systematic review and meta-Analysis of epidemiological studies. Diabetes Care 35:1171-1180.
    • (2012) Diabetes Care , vol.35 , pp. 1171-1180
    • Pan, A.1    Keum, N.2    Okereke, O.I.3    Sun, Q.4    Kivimaki, M.5    Rubin, R.R.6    Hu, F.B.7
  • 143
    • 84941024830 scopus 로고    scopus 로고
    • Abnormal gene expression of proinflammatory cytokines and their receptors in the lymphocytes of patients with bipolar disorder
    • Pandey GN, Ren X, Rizavi HS, Zhang H (2015). Abnormal gene expression of proinflammatory cytokines and their receptors in the lymphocytes of patients with bipolar disorder. Bipolar Disord 17:636-644.
    • (2015) Bipolar Disord , vol.17 , pp. 636-644
    • Pandey, G.N.1    Ren, X.2    Rizavi, H.S.3    Zhang, H.4
  • 144
    • 84902598420 scopus 로고    scopus 로고
    • Association analysis of the glucocorticoid receptor gene (nr3c1) haplotypes (er22/23ek, n363s, bcli) with mood and anxiety disorders in patients with asthma
    • Panek M, Pietras T, Szemraj J, Kuna P (2014). Association analysis of the glucocorticoid receptor gene (NR3C1) haplotypes (ER22/23EK, N363S, BclI) with mood and anxiety disorders in patients with asthma. Exp Ther Med 8:662-670.
    • (2014) Exp Ther Med , vol.8 , pp. 662-670
    • Panek, M.1    Pietras, T.2    Szemraj, J.3    Kuna, P.4
  • 145
    • 84998080646 scopus 로고    scopus 로고
    • The prevalence and mechanisms of metabolic syndrome in schizophrenia: A review
    • Papanastasiou E (2013). The prevalence and mechanisms of metabolic syndrome in schizophrenia: a review. Ther Adv Psychopharmacol 3:33-51.
    • (2013) Ther Adv Psychopharmacol , vol.3 , pp. 33-51
    • Papanastasiou, E.1
  • 146
    • 3242710339 scopus 로고    scopus 로고
    • The influence of systemic inflammation on inflammation in the brain: Implications for chronic neurodegenerative disease
    • Perry VH (2004). The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav Immun 18:407-413.
    • (2004) Brain Behav Immun , vol.18 , pp. 407-413
    • Perry, V.H.1
  • 147
    • 84930275978 scopus 로고    scopus 로고
    • Gut-microbiota-brain axis and its effect on neuropsychiatric disorders with suspected immune dysregulation
    • Petra AI, Panagiotidou S, Hatziagelaki E, Stewart JM, Conti P, Theoharides TC (2015). Gut-microbiota-brain axis and its effect on neuropsychiatric disorders with suspected immune dysregulation. Clin Ther 37:984-995.
    • (2015) Clin Ther , vol.37 , pp. 984-995
    • Petra, A.I.1    Panagiotidou, S.2    Hatziagelaki, E.3    Stewart, J.M.4    Conti, P.5    Theoharides, T.C.6
  • 148
    • 77749318422 scopus 로고    scopus 로고
    • Additive effect of polymorphisms in the il-6, lta, and TNF-(alpha) genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components
    • Phillips CM, Goumidi L, Bertrais S, Ferguson JF, Field MR, Kelly ED, et al. (2010). Additive effect of polymorphisms in the IL-6, LTA, and TNF-(alpha) genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. J Clin Endocrinol Metab 95:1386-1394.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1386-1394
    • Phillips, C.M.1    Goumidi, L.2    Bertrais, S.3    Ferguson, J.F.4    Field, M.R.5    Kelly, E.D.6
  • 149
    • 0037120334 scopus 로고    scopus 로고
    • The-174g/c polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected]
    • Pola R, Flex A, Gaetani E, Lago AD, Gerardino L, Pola P, Bernabei R (2002). The-174G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected]. Neuroreport 13:1645-1647.
    • (2002) Neuroreport , vol.13 , pp. 1645-1647
    • Pola, R.1    Flex, A.2    Gaetani, E.3    Lago, A.D.4    Gerardino, L.5    Pola, P.6    Bernabei, R.7
  • 150
    • 84919327068 scopus 로고    scopus 로고
    • Sleep duration, insomnia, and markers of systemic inflammation: Results from the netherlands study of depression and anxiety (nesda
    • Prather AA, Vogelzangs N, Penninx BW (2015). Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA). J Psychiatr Res 60:95-102.
    • (2015) J Psychiatr Res , vol.60 , pp. 95-102
    • Prather, A.A.1    Vogelzangs, N.2    Penninx, B.W.3
  • 151
    • 84942876187 scopus 로고    scopus 로고
    • Impact of comorbid depression on quality of life in male combat veterans with posttraumatic stress disorder
    • Raab PA, Mackintosh MA, Gros DF, Morland LA (2015). Impact of comorbid depression on quality of life in male combat Veterans with posttraumatic stress disorder. J Rehabil Res Dev 52:563-576.
    • (2015) J Rehabil Res Dev , vol.52 , pp. 563-576
    • Raab, P.A.1    Mackintosh, M.A.2    Gros, D.F.3    Morland, L.A.4
  • 153
    • 80053385511 scopus 로고    scopus 로고
    • Inflammatory mechanisms in major depressive disorder
    • Raedler TJ (2011). Inflammatory mechanisms in major depressive disorder. Curr Opin Psychiatry 24:519-525.
    • (2011) Curr Opin Psychiatry , vol.24 , pp. 519-525
    • Raedler, T.J.1
  • 155
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • Raison CL, Capuron L, Miller AH (2006). Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 27:24-31.
    • (2006) Trends Immunol , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 156
    • 84941209176 scopus 로고    scopus 로고
    • Plasma cytokine abnormalities in drug-naïve, comorbidity-free obsessive-compulsive disorder
    • Rao NP, Venkatasubramanian G, Ravi V, Kalmady S, Cherian A, YC JR (2015). Plasma cytokine abnormalities in drug-naïve, comorbidity-free obsessive-compulsive disorder. Psychiatry Res 229:949-952.
    • (2015) Psychiatry Res , vol.229 , pp. 949-952
    • Rao, N.P.1    Venkatasubramanian, G.2    Ravi, V.3    Kalmady, S.4    Cherian, A.5    Yc, J.R.6
  • 158
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids-new mechanisms for old drugs
    • Rhen T, Cidlowski JA (2005). Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353:1711-1723.
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 159
    • 34047266814 scopus 로고    scopus 로고
    • The link between abdominal obesity, metabolic syndrome and cardiovascular disease
    • Ritchie SA, Connell JM (2007). The link between abdominal obesity, metabolic syndrome and cardiovascular disease. Nutr Metab Cardiovasc Dis 17:319-326.
    • (2007) Nutr Metab Cardiovasc Dis , vol.17 , pp. 319-326
    • Ritchie, S.A.1    Connell, J.M.2
  • 160
    • 84896952575 scopus 로고    scopus 로고
    • Understanding ptsd comorbidity and suicidal behavior: Associations among histories of alcohol dependence, major depressive disorder, and suicidal ideation and attempts
    • Rojas SM, Bujarski S, Babson KA, Dutton CE, Feldner MT (2014). Understanding PTSD comorbidity and suicidal behavior: associations among histories of alcohol dependence, major depressive disorder, and suicidal ideation and attempts. J Anxiety Disord 28:318-325.
    • (2014) J Anxiety Disord , vol.28 , pp. 318-325
    • Rojas, S.M.1    Bujarski, S.2    Babson, K.A.3    Dutton, C.E.4    Feldner, M.T.5
  • 161
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiome shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK (2009). The gut microbiome shapes intestinal immune responses during health and disease. Nat Rev Immunol 9:313-323.
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 163
    • 11144346107 scopus 로고    scopus 로고
    • Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome
    • Salmenniemi U, Ruotsalainen E, Pihlajamäki J, Vauhkonen I, Kainulainen S, Punnonen K, et al. (2004). Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome. Circulation 110:3842-3848.
    • (2004) Circulation , vol.110 , pp. 3842-3848
    • Salmenniemi, U.1    Ruotsalainen, E.2    Pihlajamäki, J.3    Vauhkonen, I.4    Kainulainen, S.5    Punnonen, K.6
  • 164
    • 82255162413 scopus 로고    scopus 로고
    • Post-traumatic stress disorder and declarative memory functioning: A review
    • Samuelson KW (2011). Post-traumatic stress disorder and declarative memory functioning: a review. Dialogues Clin Neurosci 13:346-351.
    • (2011) Dialogues Clin Neurosci , vol.13 , pp. 346-351
    • Samuelson, K.W.1
  • 165
    • 79955125328 scopus 로고    scopus 로고
    • Genetic markers for ptsd risk and resilience among survivors of the world trade center attacks
    • Sarapas C, Cai G, Bierer LM, Golier JA, Galea S, Ising M, et al. (2011). Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks. Dis Markers 30:101-110.
    • (2011) Dis Markers , vol.30 , pp. 101-110
    • Sarapas, C.1    Cai, G.2    Bierer, L.M.3    Golier, J.A.4    Galea, S.5    Ising, M.6
  • 166
    • 79958824046 scopus 로고    scopus 로고
    • Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women
    • Sartor CE, McCutcheon VV, Pommer NE, Nelson EC, Grant JD, Duncan AE, et al. (2011). Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women. Psychol Med 41:1497-1505.
    • (2011) Psychol Med , vol.41 , pp. 1497-1505
    • Sartor, C.E.1    McCutcheon, V.V.2    Pommer, N.E.3    Nelson, E.C.4    Grant, J.D.5    Duncan, A.E.6
  • 167
    • 84878138965 scopus 로고    scopus 로고
    • Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities
    • Savitz J, Frank MB, Victor T, Bebak M, Marino JH, Bellgowan PS, et al. (2013). Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities. Brain Behav Immun 31:161-171.
    • (2013) Brain Behav Immun , vol.31 , pp. 161-171
    • Savitz, J.1    Frank, M.B.2    Victor, T.3    Bebak, M.4    Marino, J.H.5    Bellgowan, P.S.6
  • 169
    • 84881525917 scopus 로고    scopus 로고
    • Gene expression profiles in relation to tension and dissociation in borderline personality disorder
    • Schmahl C, Arvastson L, Tamm JA, Bohus M, Abdourahman A, Antonijevic I (2013). Gene expression profiles in relation to tension and dissociation in borderline personality disorder. PLoS One 8:e70787.
    • (2013) PLoS One , vol.8 , pp. e70787
    • Schmahl, C.1    Arvastson, L.2    Tamm, J.A.3    Bohus, M.4    Abdourahman, A.5    Antonijevic, I.6
  • 170
    • 18444386162 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors
    • Segman RH, Shefi N, Goltser-Dubner T, Friedman N, Kaminski N, Shalev AY (2005). Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Mol Psychiatry 10:500-513.
    • (2005) Mol Psychiatry , vol.10 , pp. 500-513
    • Segman, R.H.1    Shefi, N.2    Goltser-Dubner, T.3    Friedman, N.4    Kaminski, N.5    Shalev, A.Y.6
  • 171
    • 0037042091 scopus 로고    scopus 로고
    • Effect of il-6 polymorphism on risk of Alzheimer disease: Genotype-phenotype association study in Japanese cases
    • Shibata N, Ohnuma T, Takahashi T, Baba H, Ishizuka T, Ohtsuka M, et al. (2002). Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet 114:436-439.
    • (2002) Am J Med Genet , vol.114 , pp. 436-439
    • Shibata, N.1    Ohnuma, T.2    Takahashi, T.3    Baba, H.4    Ishizuka, T.5    Ohtsuka, M.6
  • 173
    • 84858133341 scopus 로고    scopus 로고
    • Glucocorticoid receptor 1b and 1c mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by gr gene variants
    • Sinclair D, Fullerton JM,Webster MJ, ShannonWeickert C (2012). Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants. PLoS One 7: e31720.
    • (2012) PLoS One , vol.7 , pp. e31720
    • Sinclair, D.1    Fullerton, J.M.2    Webster, M.J.3    Shannon Weickert, C.4
  • 174
    • 84896809401 scopus 로고    scopus 로고
    • Dysregulation of glucocorticoid receptor co-factors fkbp5, bag1 and ptges3 in prefrontal cortex in psychotic illness
    • Sinclair D, Fillman SG, Webster MJ, Weickert CS (2013). Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness. Sci Rep 3:3539.
    • (2013) Sci Rep , vol.3 , pp. 3539
    • Sinclair, D.1    Fillman, S.G.2    Webster, M.J.3    Weickert, C.S.4
  • 175
    • 84922642868 scopus 로고    scopus 로고
    • From stress to inflammation and major depressive disorder: A social signal transduction theory of depression
    • Slavich GM, Irwin MR (2014). From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol Bull 140:774-815.
    • (2014) Psychol Bull , vol.140 , pp. 774-815
    • Slavich, G.M.1    Irwin, M.R.2
  • 176
    • 83555176087 scopus 로고    scopus 로고
    • Risk of obesity and type 2 diabetes with tumor necrosis factor-A 308g/a gene polymorphism in metabolic syndrome and coronary artery disease subjects
    • Sobti RC, Kler R, Sharma YP, Talwar KK, Singh N (2012). Risk of obesity and type 2 diabetes with tumor necrosis factor-A 308G/A gene polymorphism in metabolic syndrome and coronary artery disease subjects. Mol Cell Biochem 360:1-7.
    • (2012) Mol Cell Biochem , vol.360 , pp. 1-7
    • Sobti, R.C.1    Kler, R.2    Sharma, Y.P.3    Talwar, K.K.4    Singh, N.5
  • 177
    • 58149484504 scopus 로고    scopus 로고
    • Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder
    • Spijker AT, van Rossum EF, Hoencamp E, DeRijk RH, Haffmans J, Blom M, et al. (2009). Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder. Bipolar Disord 11:95-101.
    • (2009) Bipolar Disord , vol.11 , pp. 95-101
    • Spijker, A.T.1    Van Rossum, E.F.2    Hoencamp, E.3    DeRijk, R.H.4    Haffmans, J.5    Blom, M.6
  • 178
    • 84905020909 scopus 로고    scopus 로고
    • Comorbidity of ptsd in anxiety and depressive disorders: Prevalence and shared risk factors
    • Spinhoven P, Penninx BW, van Hemert AM, de Rooij M, Elzinga BM (2014). Comorbidity of PTSD in anxiety and depressive disorders: prevalence and shared risk factors. Child Abuse Negl 38:1320-1330.
    • (2014) Child Abuse Negl , vol.38 , pp. 1320-1330
    • Spinhoven, P.1    Penninx, B.W.2    Van Hemert, A.M.3    De Rooij, M.4    Elzinga, B.M.5
  • 179
    • 72149124501 scopus 로고    scopus 로고
    • Association of posttraumatic stress disorder with low-grade elevation of c-reactive protein: Evidence from the general population
    • Spitzer C, Barnow S, Völzke H, Wallaschofski H, John U, Freyberger HJ, et al. (2010). Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: evidence from the general population. J Psychiatr Res 44:15-21.
    • (2010) J Psychiatr Res , vol.44 , pp. 15-21
    • Spitzer, C.1    Barnow, S.2    Völzke, H.3    Wallaschofski, H.4    John, U.5    Freyberger, H.J.6
  • 180
    • 0025363950 scopus 로고
    • Peripheral catecholamine levels and the symptoms of anxiety: Studies in patients with and without pheochromocytoma
    • Starkman MN, Cameron OG, Nesse RM, Zelnik T (1990). Peripheral catecholamine levels and the symptoms of anxiety: studies in patients with and without pheochromocytoma. Psychosom Med 52:129-142.
    • (1990) Psychosom Med , vol.52 , pp. 129-142
    • Starkman, M.N.1    Cameron, O.G.2    Nesse, R.M.3    Zelnik, T.4
  • 181
    • 0036789213 scopus 로고    scopus 로고
    • Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: A twin study
    • Stein MB, Jang KL, Taylor S, Vernon PA, Livesley WJ (2002). Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study. Am J Psychiatry 159:1675-1681.
    • (2002) Am J Psychiatry , vol.159 , pp. 1675-1681
    • Stein, M.B.1    Jang, K.L.2    Taylor, S.3    Vernon, P.A.4    Livesley, W.J.5
  • 182
    • 84899121900 scopus 로고    scopus 로고
    • Changes in fkbp5 expression and memory functions during cognitive-behavioral therapy in posttraumatic stress disorder: A preliminary study
    • Szabó C, Kelemen O, Kéri S (2014). Changes in FKBP5 expression and memory functions during cognitive-behavioral therapy in posttraumatic stress disorder: a preliminary study. Neurosci Lett 569:116-120.
    • (2014) Neurosci Lett , vol.569 , pp. 116-120
    • Szabó, C.1    Kelemen, O.2    Kéri, S.3
  • 183
  • 185
    • 61449224570 scopus 로고    scopus 로고
    • Microglia: Gatekeepers of central nervous system immunology
    • Tambuyzer BR, Ponsaerts P, Nouwen EJ (2009). Microglia: gatekeepers of central nervous system immunology. J Leukoc Biol 85:352-370.
    • (2009) J Leukoc Biol , vol.85 , pp. 352-370
    • Tambuyzer, B.R.1    Ponsaerts, P.2    Nouwen, E.J.3
  • 186
    • 84893734805 scopus 로고    scopus 로고
    • Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease
    • Taylor JM, Minter MR, Newman AG, Zhang M, Adlard PA, Crack PJ (2014). Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol Aging 35:1012-1023.
    • (2014) Neurobiol Aging , vol.35 , pp. 1012-1023
    • Taylor, J.M.1    Minter, M.R.2    Newman, A.G.3    Zhang, M.4    Adlard, P.A.5    Crack, P.J.6
  • 188
    • 84926526782 scopus 로고    scopus 로고
    • Polymorphisms of ikbke gene are associated with major depressive disorder and panic disorder
    • Traks T, Koido K, Balõtšev R, Eller T, Kõks S, Maron E, et al. (2015). Polymorphisms of IKBKE gene are associated with major depressive disorder and panic disorder. Brain Behav 5:e00314.
    • (2015) Brain Behav , vol.5 , pp. e00314
    • Traks, T.1    Koido, K.2    Balõtšev, R.3    Eller, T.4    Kõks, S.5    Maron, E.6
  • 189
  • 195
    • 84856005896 scopus 로고    scopus 로고
    • Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: A prospective study
    • Van Zuiden M, Geuze E, Willemen HL, Vermetten E, Maas M, Amarouchi K, et al. (2012). Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study. Biol Psychiatry 71:309-316.
    • (2012) Biol Psychiatry , vol.71 , pp. 309-316
    • Van Zuiden, M.1    Geuze, E.2    Willemen, H.L.3    Vermetten, E.4    Maas, M.5    Amarouchi, K.6
  • 197
    • 34247547482 scopus 로고    scopus 로고
    • Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder
    • Von Känel R, Hepp U, Kraemer B, Traber R, Keel M, Mica L, Schnyder U (2007). Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res 41:744-752.
    • (2007) J Psychiatr Res , vol.41 , pp. 744-752
    • Von Känel, R.1    Hepp, U.2    Kraemer, B.3    Traber, R.4    Keel, M.5    Mica, L.6    Schnyder, U.7
  • 198
    • 79953667345 scopus 로고    scopus 로고
    • Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy
    • Wang Y, Hancock AM, Bradner J, Chung KA, Quinn JF, Peskind ER, et al. (2011). Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy. Am J Pathol 178:1509-1516.
    • (2011) Am J Pathol , vol.178 , pp. 1509-1516
    • Wang, Y.1    Hancock, A.M.2    Bradner, J.3    Chung, K.A.4    Quinn, J.F.5    Peskind, E.R.6
  • 200
    • 38149045133 scopus 로고    scopus 로고
    • Low-grade inflammation and the metabolic syndrome in children and adolescents
    • Wärnberg J, Marcos A (2008). Low-grade inflammation and the metabolic syndrome in children and adolescents. Curr Opin Lipidol 19:11-15.
    • (2008) Curr Opin Lipidol , vol.19 , pp. 11-15
    • Wärnberg, J.1    Marcos, A.2
  • 201
    • 79956035554 scopus 로고    scopus 로고
    • Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population
    • Weiss T, Skelton K, Phifer J, Jovanovic T, Gillespie CF, Smith A, et al. (2011). Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population. Gen Hosp Psychiatry 33:135-142.
    • (2011) Gen Hosp Psychiatry , vol.33 , pp. 135-142
    • Weiss, T.1    Skelton, K.2    Phifer, J.3    Jovanovic, T.4    Gillespie, C.F.5    Smith, A.6
  • 204
    • 84885132242 scopus 로고    scopus 로고
    • Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model
    • Wilson CB, McLaughlin LD, Nair A, Ebenezer PJ, Dange R, Francis J (2013). Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model. PLoS One 8:e76146.
    • (2013) PLoS One , vol.8 , pp. e76146
    • Wilson, C.B.1    McLaughlin, L.D.2    Nair, A.3    Ebenezer, P.J.4    Dange, R.5    Francis, J.6
  • 205
    • 84863380407 scopus 로고    scopus 로고
    • The role of gut microbiota in immune homeostasis and autoimmunity
    • Wu HJ, Wu E (2012). The role of gut microbiota in immune homeostasis and autoimmunity. Gut Microbes 3:4-14.
    • (2012) Gut Microbes , vol.3 , pp. 4-14
    • Wu, H.J.1    Wu, E.2
  • 206
    • 34548176975 scopus 로고    scopus 로고
    • Interleukin-1 alpha polymorphism has influence on late-onset sporadic Parkinson's disease in Taiwan
    • Wu YR, Chen CM, Hwang JC, Chen ST, Feng IH, Hsu HC, et al. (2007a). Interleukin-1 alpha polymorphism has influence on late-onset sporadic Parkinson's disease in Taiwan. J Neural Transm (Vienna) 114:1173-1177.
    • (2007) J Neural Transm (Vienna , vol.114 , pp. 1173-1177
    • Wu, Y.R.1    Chen, C.M.2    Hwang, J.C.3    Chen, S.T.4    Feng, I.H.5    Hsu, H.C.6
  • 207
    • 34247323856 scopus 로고    scopus 로고
    • Tumor necrosis factor-Alpha promoter polymorphism is associated with the risk of Parkinson's disease
    • Wu YR, Feng IH, Lyu RK, Chang KH, Lin YY, Chan H, et al. (2007b). Tumor necrosis factor-Alpha promoter polymorphism is associated with the risk of Parkinson's disease. Am J Med Genet B Neuropsychiatr Genet 144B:300-304.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 B , pp. 300-304
    • Wu, Y.R.1    Feng, I.H.2    Lyu, R.K.3    Chang, K.H.4    Lin, Y.Y.5    Chan, H.6
  • 209
    • 84885424758 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder
    • Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J (2013). Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry 74:656-663.
    • (2013) Biol Psychiatry , vol.74 , pp. 656-663
    • Xie, P.1    Kranzler, H.R.2    Yang, C.3    Zhao, H.4    Farrer, L.A.5    Gelernter, J.6
  • 211
    • 84911976985 scopus 로고    scopus 로고
    • Polymorphisms in nr3c1 gene associated with risk of metabolic syndrome in a Chinese population
    • Yan YX, Dong J, Zhang J, Liu F, Wang W, Zhang L, He Y (2014). Polymorphisms in NR3C1 gene associated with risk of metabolic syndrome in a Chinese population. Endocrine 47:740-748.
    • (2014) Endocrine , vol.47 , pp. 740-748
    • Yan, Y.X.1    Dong, J.2    Zhang, J.3    Liu, F.4    Wang, W.5    Zhang, L.6    He, Y.7
  • 212
    • 2542423960 scopus 로고    scopus 로고
    • Enhanced sensitivity to glucocorticoids in peripheral mononuclear leukocytes in posttraumatic stress disorder
    • Yehuda R, Golier JA, Yang RK, Tischler L (2004). Enhanced sensitivity to glucocorticoids in peripheral mononuclear leukocytes in posttraumatic stress disorder. Biol Psychiatry 55:1110-1116.
    • (2004) Biol Psychiatry , vol.55 , pp. 1110-1116
    • Yehuda, R.1    Golier, J.A.2    Yang, R.K.3    Tischler, L.4
  • 213
    • 69749097818 scopus 로고    scopus 로고
    • Gene expression patterns associated with posttraumatic stress disorder following exposure to the world trade center attacks
    • Yehuda R, Cai G, Golier JA, Sarapas C, Galea S, Ising M, et al. (2009). Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks. Biol Psychiatry 66:708-711.
    • (2009) Biol Psychiatry , vol.66 , pp. 708-711
    • Yehuda, R.1    Cai, G.2    Golier, J.A.3    Sarapas, C.4    Galea, S.5    Ising, M.6
  • 214
    • 78651412528 scopus 로고    scopus 로고
    • Immune modulation of learning, memory, neural plasticity and neurogenesis
    • Yirmiya R, Goshen I (2011). Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav Immun 25:181-213.
    • (2011) Brain Behav Immun , vol.25 , pp. 181-213
    • Yirmiya, R.1    Goshen, I.2
  • 215
    • 1842528209 scopus 로고    scopus 로고
    • Cortisol and catecholamines in posttraumatic stress disorder: An epidemiologic community study
    • Young EA, Breslau N (2004). Cortisol and catecholamines in posttraumatic stress disorder: an epidemiologic community study. Arch Gen Psychiatry 61:394-401.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 394-401
    • Young, E.A.1    Breslau, N.2
  • 216
    • 0042844775 scopus 로고    scopus 로고
    • Association study of the interleukin-1 beta (c-511 t) genetic polymorphism with major depressive disorder, associated symptomatology, and antidepressant response
    • Yu YWY, Chen TJ, Hong CJ, Chen HM, Tsai SJ (2003). Association study of the interleukin-1 beta (C-511 T) genetic polymorphism with major depressive disorder, associated symptomatology, and antidepressant response. Neuropsychopharmacol 28:1182-1185.
    • (2003) Neuropsychopharmacol , vol.28 , pp. 1182-1185
    • Yu, Y.W.Y.1    Chen, T.J.2    Hong, C.J.3    Chen, H.M.4    Tsai, S.J.5
  • 218
    • 2942531060 scopus 로고    scopus 로고
    • Interleukin-6 promoter polymorphism: Risk and pathology of Alzheimer's disease
    • Zhang Y, Hayes A, Pritchard A, Thaker U, Haque MS, Lemmon H, et al. (2004). Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease. Neurosci Lett 362:99-102.
    • (2004) Neurosci Lett , vol.362 , pp. 99-102
    • Zhang, Y.1    Hayes, A.2    Pritchard, A.3    Thaker, U.4    Haque, M.S.5    Lemmon, H.6
  • 219
    • 33846484434 scopus 로고    scopus 로고
    • Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder
    • Zieker J, Zieker D, Jatzko A, Dietzsch J, Nieselt K, Schmitt A, et al. (2007). Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder. Mol Psychiatry 12:116-118.
    • (2007) Mol Psychiatry , vol.12 , pp. 116-118
    • Zieker, J.1    Zieker, D.2    Jatzko, A.3    Dietzsch, J.4    Nieselt, K.5    Schmitt, A.6
  • 221
    • 84864777651 scopus 로고    scopus 로고
    • Psychosocial animal model of ptsd produces a long-lasting traumatic memory, an increase in general anxiety and ptsd-like glucocorticoid abnormalities
    • Zoladz PR, Fleshner M, Diamond DM (2012). Psychosocial animal model of PTSD produces a long-lasting traumatic memory, an increase in general anxiety and PTSD-like glucocorticoid abnormalities. Psychoneuroendocrinology 37: 1531-1545.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 1531-1545
    • Zoladz, P.R.1    Fleshner, M.2    Diamond, D.M.3


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