메뉴 건너뛰기




Volumn 3, Issue 1, 2012, Pages

The role of gut microbiota in immune homeostasis and autoimmunity

Author keywords

Animal model; Antibiotics; Autoimmune; Commensal; Cytokine; Germ free; Microbiota; Mucosal immunity

Indexed keywords

INTERLEUKIN 17;

EID: 84863380407     PISSN: 19490976     EISSN: 19490984     Source Type: Journal    
DOI: 10.4161/gmic.19320     Document Type: Review
Times cited : (940)

References (118)
  • 1
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • PMID: 16497592
    • Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006; 124:837-48; PMID: 16497592; http://dx.doi.org/10.1016/j.cell.2006.02.017.
    • (2006) Cell , vol.124 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 2
    • 52049092682 scopus 로고    scopus 로고
    • Worlds within worlds: Evolution of the vertebrate gut microbiota
    • PMID:18794915
    • Ley RE, Lozupone CA, Hamady M, Knight R, Gordon JI. Worlds within worlds: evolution of the vertebrate gut microbiota. Nat Rev Microbiol 2008; 6:776-88; PMID:18794915; http://dx.doi.org/10.1038/nrmicro1978.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 776-788
    • Ley, R.E.1    Lozupone, C.A.2    Hamady, M.3    Knight, R.4    Gordon, J.I.5
  • 3
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • PMID: 15790844
    • Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. Science 2005; 307:1915-20; PMID: 15790844; http://dx.doi.org/10.1126/science.1104816.
    • (2005) Science , vol.307 , pp. 1915-1920
    • Bäckhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3    Peterson, D.A.4    Gordon, J.I.5
  • 4
    • 70349292139 scopus 로고    scopus 로고
    • Induction of intestinal lymphoid tissue formation by intrinsic and extrinsic signals
    • PMID:19506873
    • Finke D. Induction of intestinal lymphoid tissue formation by intrinsic and extrinsic signals. Semin Immunopathol 2009; 31:151-69; PMID:19506873; http://dx.doi.org/10.1007/s00281-009-0163-6.
    • (2009) Semin Immunopathol , vol.31 , pp. 151-169
    • Finke, D.1
  • 5
    • 77952318832 scopus 로고    scopus 로고
    • Intestinal bacteria and the regulation of immune cell homeostasis
    • PMID:20192812
    • Hill DA, Artis D. Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol 2010; 28:623-67; PMID:20192812; http://dx.doi.org/10.1146/annurev-immunol-030409-101330.
    • (2010) Annu Rev Immunol , vol.28 , pp. 623-667
    • Hill, D.A.1    Artis, D.2
  • 6
    • 20444485767 scopus 로고    scopus 로고
    • Cellular and genetic mechanisms of self tolerance and autoimmunity
    • PMID: 15931211
    • Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 2005; 435:590-7; PMID: 15931211; http://dx.doi.org/10.1038/nature03724.
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2    de Fazekas, S.3    Groth, B.4    Vinuesa, C.G.5
  • 7
    • 56349102675 scopus 로고    scopus 로고
    • Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency-lessons learned from monogenic disorders in mice and men
    • PMID:18955138
    • Westerberg LS, Klein C, Snapper SB. Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency-lessons learned from monogenic disorders in mice and men. Curr Opin Immunol 2008; 20:646-54; PMID:18955138; http://dx.doi.org/10.1016/j.coi.2008.10.004.
    • (2008) Curr Opin Immunol , vol.20 , pp. 646-654
    • Westerberg, L.S.1    Klein, C.2    Snapper, S.B.3
  • 9
    • 66349083859 scopus 로고    scopus 로고
    • NISC Comparative Sequencing Program. Topographical and temporal diversity of the human skin microbiome
    • PMID:19478181
    • Grice EA, Kong HH, Conlan S, Deming CB, Davis J, Young AC, et al & NISC Comparative Sequencing Program. Topographical and temporal diversity of the human skin microbiome. Science 2009; 324:1190-2; PMID:19478181; http://dx.doi.org/10.1126/science.1171700.
    • (2009) Science , vol.324 , pp. 1190-1192
    • Grice, E.A.1    Kong, H.H.2    Conlan, S.3    Deming, C.B.4    Davis, J.5    Young, A.C.6
  • 10
    • 34547129847 scopus 로고    scopus 로고
    • Development of the human infant intestinal microbiota
    • PMID:17594176
    • Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO. Development of the human infant intestinal microbiota. PLoS Biol 2007; 5:e177; PMID:17594176; http://dx.doi.org/10.1371/journal.pbio.0050177.
    • (2007) PLoS Biol , vol.5 , pp. 177
    • Palmer, C.1    Bik, E.M.2    Digiulio, D.B.3    Relman, D.A.4    Brown, P.O.5
  • 11
  • 12
    • 34249284197 scopus 로고    scopus 로고
    • Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota
    • PMID:17118672
    • Smith K, McCoy KD, Macpherson AJ. Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota. Semin Immunol 2007; 19:59-69; PMID:17118672; http://dx.doi.org/10.1016/j.smim.2006.10.002.
    • (2007) Semin Immunol , vol.19 , pp. 59-69
    • Smith, K.1    McCoy, K.D.2    Macpherson, A.J.3
  • 13
    • 53649106826 scopus 로고    scopus 로고
    • Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection
    • PMID: 18678663
    • Sekirov I, Tam NM, Jogova M, Robertson ML, Li Y, Lupp C, et al. Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun 2008; 76:4726-36; PMID: 18678663; http://dx.doi.org/10.1128/IAI.00319-08.
    • (2008) Infect Immun , vol.76 , pp. 4726-4736
    • Sekirov, I.1    Tam, N.M.2    Jogova, M.3    Robertson, M.L.4    Li, Y.5    Lupp, C.6
  • 14
    • 77249163771 scopus 로고    scopus 로고
    • Metagenomic analyses reveal antibioticinduced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis
    • PMID: 19940845
    • Hill DA, Hoffmann C, Abt MC, Du Y, Kobuley D, Kirn TJ, et al. Metagenomic analyses reveal antibioticinduced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunol 2010; 3:148-58; PMID: 19940845; http://dx.doi.org/10.1038/mi.2009.132.
    • (2010) Mucosal Immunol , vol.3 , pp. 148-158
    • Hill, D.A.1    Hoffmann, C.2    Abt, M.C.3    Du, Y.4    Kobuley, D.5    Kirn, T.J.6
  • 15
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • PMID:15260992
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F,Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004; 118:229-41; PMID:15260992; http://dx.doi.org/10.1016/j.cell.2004.07.002.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 16
    • 77953913586 scopus 로고    scopus 로고
    • Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
    • PMID:20620945
    • Wu HJ, Ivanov II, Darce J, Hattori K, Shima T, Umesaki Y, et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 2010; 32:815-27; PMID:20620945; http://dx.doi.org/10.1016/j.immuni.2010.06.001.
    • (2010) Immunity , vol.32 , pp. 815-827
    • Wu, H.J.1    Ivanov, I.I.2    Darce, J.3    Hattori, K.4    Shima, T.5    Umesaki, Y.6
  • 17
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • PMID:19836068
    • Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009; 139:485-98; PMID:19836068; http://dx.doi.org/10.1016/j.cell.2009.09.033.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3    Brodie, E.L.4    Shima, T.5    Karaoz, U.6
  • 18
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • PMID:16009137
    • Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005; 122:107-18; PMID:16009137; http://dx.doi.org/10.1016/j.cell.2005.05.007.
    • (2005) Cell , vol.122 , pp. 107-118
    • Mazmanian, S.K.1    Liu, C.H.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 19
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • PMID:10432286
    • Iwasaki A, Kelsall BL. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J Exp Med 1999; 190:229-39; PMID:10432286; http://dx.doi.org/10.1084/jem.190.2.229.
    • (1999) J Exp Med , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 20
    • 13744256812 scopus 로고    scopus 로고
    • Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity
    • PMID:15630445
    • Smythies LE, Sellers M, Clements RH, Mosteller-Barnum M, Meng G, Benjamin WH, et al. Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest 2005; 115:66-75; PMID:15630445.
    • (2005) J Clin Invest , vol.115 , pp. 66-75
    • Smythies, L.E.1    Sellers, M.2    Clements, R.H.3    Mosteller-Barnum, M.4    Meng, G.5    Benjamin, W.H.6
  • 21
    • 77953482525 scopus 로고    scopus 로고
    • Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation
    • PMID:20388715
    • Smythies LE, Shen R, Bimczok D, Novak L, Clements RH, Eckhoff DE, et al. Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation. J Biol Chem 2010; 285:19593-604; PMID:20388715; http://dx.doi.org/10.1074/jbc.M109.069955.
    • (2010) J Biol Chem , vol.285 , pp. 19593-19604
    • Smythies, L.E.1    Shen, R.2    Bimczok, D.3    Novak, L.4    Clements, R.H.5    Eckhoff, D.E.6
  • 22
    • 34548428699 scopus 로고    scopus 로고
    • Immune development in jejunal mucosa after colonization with selected commensal gut bacteria: A study in germ-free pigs
    • PMID:17643495
    • Haverson K, Rehakova Z, Sinkora J, Sver L, Bailey M. Immune development in jejunal mucosa after colonization with selected commensal gut bacteria: a study in germ-free pigs. Vet Immunol Immunopathol 2007; 119:243-53; PMID:17643495; http://dx.doi.org/10.1016/j.vetimm.2007.05.022.
    • (2007) Vet Immunol Immunopathol , vol.119 , pp. 243-253
    • Haverson, K.1    Rehakova, Z.2    Sinkora, J.3    Sver, L.4    Bailey, M.5
  • 23
    • 33750887563 scopus 로고    scopus 로고
    • Effects of microflora on the neonatal development of gut mucosal T cells and myeloid cells in the mouse
    • PMID:16995882
    • Williams AM, Probert CS, Stepankova R, Tlaskalova-Hogenova H, Phillips A, Bland PW. Effects of microflora on the neonatal development of gut mucosal T cells and myeloid cells in the mouse. Immunology 2006; 119:470-8; PMID:16995882; http://dx.doi.org/10.1111/j.1365-2567.2006.02458.x.
    • (2006) Immunology , vol.119 , pp. 470-478
    • Williams, A.M.1    Probert, C.S.2    Stepankova, R.3    Tlaskalova-Hogenova, H.4    Phillips, A.5    Bland, P.W.6
  • 24
    • 53649100675 scopus 로고    scopus 로고
    • ATP drives lamina propria T(H)17 cell differentiation
    • PMID:18716618
    • Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, et al. ATP drives lamina propria T(H)17 cell differentiation. Nature 2008; 455:808-12; PMID:18716618; http://dx.doi.org/10.1038/nature07240.
    • (2008) Nature , vol.455 , pp. 808-812
    • Atarashi, K.1    Nishimura, J.2    Shima, T.3    Umesaki, Y.4    Yamamoto, M.5    Onoue, M.6
  • 25
    • 0021958660 scopus 로고
    • Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80
    • PMID:3973536
    • Lee SH, Starkey PM, Gordon S. Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80. J Exp Med 1985; 161:475-89; PMID:3973536; http://dx.doi.org/10.1084/jem.161.3.475.
    • (1985) J Exp Med , vol.161 , pp. 475-489
    • Lee, S.H.1    Starkey, P.M.2    Gordon, S.3
  • 26
    • 38549166401 scopus 로고    scopus 로고
    • Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs
    • PMID:18006076
    • Zhang W, Wen K, Azevedo MS, Gonzalez A, Saif LJ, Li G, et al. Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs. Vet Immunol Immunopathol 2008; 121:222-31; PMID:18006076; http://dx.doi.org/10.1016/j.vetimm.2007.10.001.
    • (2008) Vet Immunol Immunopathol , vol.121 , pp. 222-231
    • Zhang, W.1    Wen, K.2    Azevedo, M.S.3    Gonzalez, A.4    Saif, L.J.5    Li, G.6
  • 27
    • 17644440155 scopus 로고
    • Phagocytosis, peritoneal influx, and enzyme activities in peritoneal macrophages from germfree, conventional, and ex-germfree mice
    • PMID:6233226
    • Mørland B, Midtvedt T. Phagocytosis, peritoneal influx, and enzyme activities in peritoneal macrophages from germfree, conventional, and ex-germfree mice. Infect Immun 1984; 44:750-2; PMID:6233226.
    • (1984) Infect Immun , vol.44 , pp. 750-752
    • Mørland, B.1    Midtvedt, T.2
  • 28
    • 0022652178 scopus 로고
    • Ontogeny of macrophage function to release superoxide anion in conventional and germfree mice
    • PMID:3007361
    • Mitsuyama M, Ohara R, Amako K, Nomoto K, Yokokura T, Nomoto K. Ontogeny of macrophage function to release superoxide anion in conventional and germfree mice. Infect Immun 1986; 52:236-9; PMID:3007361.
    • (1986) Infect Immun , vol.52 , pp. 236-239
    • Mitsuyama, M.1    Ohara, R.2    Amako, K.3    Nomoto, K.4    Yokokura, T.5    Nomoto, K.6
  • 29
    • 16644399114 scopus 로고    scopus 로고
    • Macrophages in the small intestinal muscularis externa of embryos, newborn and adult germ-free mice
    • PMID:15503811
    • Mikkelsen HB, Garbarsch C, Tranum-Jensen J, Thuneberg L. Macrophages in the small intestinal muscularis externa of embryos, newborn and adult germ-free mice. J Mol Histol 2004; 35:377-87; PMID:15503811; http://dx.doi.org/10.1023/B:HIJO.0000039840.86420.b7.
    • (2004) J Mol Histol , vol.35 , pp. 377-387
    • Mikkelsen, H.B.1    Garbarsch, C.2    Tranum-Jensen, J.3    Thuneberg, L.4
  • 30
    • 0025225513 scopus 로고
    • Impaired superoxide production in peripheral blood neutrophils of germ-free rats
    • PMID:1702900
    • Ohkubo T, Tsuda M, Tamura M, Yamamura M. Impaired superoxide production in peripheral blood neutrophils of germ-free rats. Scand J Immunol 1990; 32:727-9; PMID:1702900; http://dx.doi.org/10.1111/j.1365-3083.1990.tb03216.x.
    • (1990) Scand J Immunol , vol.32 , pp. 727-729
    • Ohkubo, T.1    Tsuda, M.2    Tamura, M.3    Yamamura, M.4
  • 31
    • 0032922567 scopus 로고    scopus 로고
    • Peripheral blood neutrophils of germfree rats modified by in vivo granulocyte-colonystimulating factor and exposure to natural environment
    • PMID:10023860
    • Ohkubo T, Tsuda M, Suzuki S, El Borai N, Yamamura M. Peripheral blood neutrophils of germfree rats modified by in vivo granulocyte-colonystimulating factor and exposure to natural environment. Scand J Immunol 1999; 49:73-7; PMID:10023860; http://dx.doi.org/10.1046/j.1365-3083.1999.00456.x.
    • (1999) Scand J Immunol , vol.49 , pp. 73-77
    • Ohkubo, T.1    Tsuda, M.2    Suzuki, S.3    El Borai, N.4    Yamamura, M.5
  • 32
    • 76249120134 scopus 로고    scopus 로고
    • Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity
    • PMID:20081863
    • Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med 2010; 16:228-31; PMID:20081863; http://dx.doi.org/10.1038/nm.2087.
    • (2010) Nat Med , vol.16 , pp. 228-231
    • Clarke, T.B.1    Davis, K.M.2    Lysenko, E.S.3    Zhou, A.Y.4    Yu, Y.5    Weiser, J.N.6
  • 33
    • 57449118239 scopus 로고    scopus 로고
    • Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
    • PMID:19084435
    • Satoh-Takayama N, Vosshenrich CA, Lesjean-Pottier S, Sawa S, Lochner M, Rattis F, et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 2008; 29:958-70; PMID:19084435; http://dx.doi.org/10.1016/j.immuni.2008.11.001.
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1    Vosshenrich, C.A.2    Lesjean-Pottier, S.3    Sawa, S.4    Lochner, M.5    Rattis, F.6
  • 34
    • 57849117363 scopus 로고    scopus 로고
    • RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
    • PMID:19029903
    • Sanos SL, Bui VL, Mortha A, Oberle K, Heners C, Johner C, et al. RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat Immunol 2009; 10:83-91; PMID:19029903; http://dx.doi.org/10.1038/ni.1684.
    • (2009) Nat Immunol , vol.10 , pp. 83-91
    • Sanos, S.L.1    Bui, V.L.2    Mortha, A.3    Oberle, K.4    Heners, C.5    Johner, C.6
  • 35
    • 70349279924 scopus 로고    scopus 로고
    • Physiological and pathophysiological functions of intestinal mast cells
    • PMID:19533134
    • Bischoff SC. Physiological and pathophysiological functions of intestinal mast cells. Semin Immunopathol 2009; 31:185-205; PMID:19533134; http://dx.doi.org/10.1007/s00281-009-0165-4.
    • (2009) Semin Immunopathol , vol.31 , pp. 185-205
    • Bischoff, S.C.1
  • 36
    • 79955527625 scopus 로고    scopus 로고
    • Commensal bacteria promote migration of mast cells into the intestine
    • PMID:21281976
    • Kunii J, Takahashi K, Kasakura K, TsudaM, Nakano K, Hosono A, et al. Commensal bacteria promote migration of mast cells into the intestine. Immunobiology 2011; 216:692-7; PMID:21281976; http://dx.doi.org/10.1016/j.imbio.2010.10.007.
    • (2011) Immunobiology , vol.216 , pp. 692-697
    • Kunii, J.1    Takahashi, K.2    Kasakura, K.3    Tsuda, M.4    Nakano, K.5    Hosono, A.6
  • 37
    • 0014574973 scopus 로고
    • Small intestinal mucosal cell proliferation and bacterial flora in the conventionalization of the germfree mouse
    • PMID:4896909
    • Khoury KA, Floch MH, Hersh T. Small intestinal mucosal cell proliferation and bacterial flora in the conventionalization of the germfree mouse. J Exp Med 1969; 130:659-70; PMID:4896909; http://dx.doi.org/10.1084/jem.130.3.659.
    • (1969) J Exp Med , vol.130 , pp. 659-670
    • Khoury, K.A.1    Floch, M.H.2    Hersh, T.3
  • 38
    • 79952855316 scopus 로고    scopus 로고
    • Depletion of murine intestinal microbiota: Effects on gut mucosa and epithelial gene expression
    • PMID:21445311
    • Reikvam DH, Erofeev A, Sandvik A, Grcic V, Jahnsen FL, Gaustad P, et al. Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression. PLoSOne 2011; 6:e17996; PMID:21445311; http://dx.doi.org/10.1371/journal.pone.0017996.
    • (2011) PLoSOne , vol.6 , pp. 17996
    • Reikvam, D.H.1    Erofeev, A.2    Sandvik, A.3    Grcic, V.4    Jahnsen, F.L.5    Gaustad, P.6
  • 39
    • 0036971220 scopus 로고    scopus 로고
    • The functions of mucosal T cells in containing the indigenous commensal flora of the intestine
    • PMID:12568335
    • Macpherson AJ, Martinic MM, Harris N. The functions of mucosal T cells in containing the indigenous commensal flora of the intestine. Cell Mol Life Sci 2002; 59:2088-96; PMID:12568335; http://dx.doi.org/10.1007/s000180200009.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 2088-2096
    • Macpherson, A.J.1    Martinic, M.M.2    Harris, N.3
  • 40
    • 70349742524 scopus 로고    scopus 로고
    • The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
    • PMID:19833089
    • Gaboriau-Routhiau V, Rakotobe S, Lécuyer E, Mulder I, Lan A, Bridonneau C, et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity 2009; 31:677-89; PMID:19833089; http://dx.doi.org/10.1016/j.immuni.2009.08.020.
    • (2009) Immunity , vol.31 , pp. 677-689
    • Gaboriau-Routhiau, V.1    Rakotobe, S.2    Lécuyer, E.3    Mulder, I.4    Lan, A.5    Bridonneau, C.6
  • 41
    • 80051994193 scopus 로고    scopus 로고
    • The lifestyle of the segmented filamentous bacterium: A non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing
    • PMID: 21791478
    • Kuwahara T, Ogura Y, Oshima K, Kurokawa K, Ooka T, Hirakawa H, et al. The lifestyle of the segmented filamentous bacterium: a non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing. DNA Res 2011; 18:291-303; PMID: 21791478; http://dx.doi.org/10.1093/dnares/dsr022.
    • (2011) DNA Res , vol.18 , pp. 291-303
    • Kuwahara, T.1    Ogura, Y.2    Oshima, K.3    Kurokawa, K.4    Ooka, T.5    Hirakawa, H.6
  • 42
    • 80053025965 scopus 로고    scopus 로고
    • The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment
    • PMID:21925113
    • Sczesnak A, Segata N, Qin X, Gevers D, Petrosino JF, Huttenhower C, et al. The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment. Cell Host Microbe 2011; 10:260-72; PMID:21925113; http://dx.doi.org/10.1016/j.chom.2011.08.005.
    • (2011) Cell Host Microbe , vol.10 , pp. 260-272
    • Sczesnak, A.1    Segata, N.2    Qin, X.3    Gevers, D.4    Petrosino, J.F.5    Huttenhower, C.6
  • 43
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous Clostridium species
    • PMID:21205640
    • Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011; 331:337-41; PMID:21205640; http://dx.doi.org/10.1126/science.1198469.
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3    Imaoka, A.4    Kuwahara, T.5    Momose, Y.6
  • 44
    • 53349164200 scopus 로고    scopus 로고
    • Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
    • PMID: 18835196
    • Hall JA, Bouladoux N, Sun CM, Wohlfert EA, Blank RB, Zhu Q, et al. Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses. Immunity 2008; 29:637-49; PMID: 18835196; http://dx.doi.org/10.1016/j.immuni.2008.08.009.
    • (2008) Immunity , vol.29 , pp. 637-649
    • Hall, J.A.1    Bouladoux, N.2    Sun, C.M.3    Wohlfert, E.A.4    Blank, R.B.5    Zhu, Q.6
  • 45
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • PMID:21512004
    • Round JL, Lee SM, Li J, Tran G, Jabri B, Chatila TA, et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011; 332:974-7; PMID:21512004; http://dx.doi.org/10.1126/science.1206095.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5    Chatila, T.A.6
  • 46
    • 80054020840 scopus 로고    scopus 로고
    • Peripheral education of the immune system by colonic commensal microbiota
    • PMID:21937990
    • Lathrop SK, Bloom SM, Rao SM, Nutsch K, Lio CW, Santacruz N, et al. Peripheral education of the immune system by colonic commensal microbiota. Nature 2011; 478:250-4; PMID:21937990; http://dx.doi.org/10.1038/nature10434.
    • (2011) Nature , vol.478 , pp. 250-254
    • Lathrop, S.K.1    Bloom, S.M.2    Rao, S.M.3    Nutsch, K.4    Lio, C.W.5    Santacruz, N.6
  • 47
    • 0029970242 scopus 로고    scopus 로고
    • Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice
    • PMID: 8625993
    • Imaoka A, Matsumoto S, Setoyama H, Okada Y, Umesaki Y. Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice. Eur J Immunol 1996; 26:945-8; PMID: 8625993; http://dx.doi.org/10.1002/eji.1830260434.
    • (1996) Eur J Immunol , vol.26 , pp. 945-948
    • Imaoka, A.1    Matsumoto, S.2    Setoyama, H.3    Okada, Y.4    Umesaki, Y.5
  • 48
    • 10244263593 scopus 로고    scopus 로고
    • Development and cytolytic function of intestinal intraepithelial T lymphocytes in antigen-minimized mice
    • PMID:8943725
    • Kawaguchi-Miyashita M, Shimizu K, Nanno M, Shimada S, Watanabe T, Koga Y, et al. Development and cytolytic function of intestinal intraepithelial T lymphocytes in antigen-minimized mice. Immunology 1996; 89:268-73; PMID:8943725; http://dx.doi.org/10.1046/j.1365-2567.1996.d01-740.x.
    • (1996) Immunology , vol.89 , pp. 268-273
    • Kawaguchi-Miyashita, M.1    Shimizu, K.2    Nanno, M.3    Shimada, S.4    Watanabe, T.5    Koga, Y.6
  • 49
    • 10944226920 scopus 로고    scopus 로고
    • Microbial colonization induces oligoclonal expansions of intraepithelial CD8 T cells in the gut
    • PMID:15517613
    • Helgeland L, Dissen E, Dai KZ, Midtvedt T, Brandtzaeg P, Vaage JT. Microbial colonization induces oligoclonal expansions of intraepithelial CD8 T cells in the gut. Eur J Immunol 2004; 34: 3389-400; PMID:15517613; http://dx.doi.org/10.1002/eji.200425122.
    • (2004) Eur J Immunol , vol.34 , pp. 3389-3400
    • Helgeland, L.1    Dissen, E.2    Dai, K.Z.3    Midtvedt, T.4    Brandtzaeg, P.5    Vaage, J.T.6
  • 50
    • 59749098602 scopus 로고    scopus 로고
    • Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells
    • PMID: 19009526
    • Wei B, Su TT, Dalwadi H, Stephan RP, Fujiwara D, Huang TT, et al. Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells. Eur J Immunol 2008; 38:3411-25; PMID: 19009526; http://dx.doi.org/10.1002/eji.200838432.
    • (2008) Eur J Immunol , vol.38 , pp. 3411-3425
    • Wei, B.1    Su, T.T.2    Dalwadi, H.3    Stephan, R.P.4    Fujiwara, D.5    Huang, T.T.6
  • 51
    • 44449093654 scopus 로고    scopus 로고
    • Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota
    • PMID: 18424703
    • Fujiwara D, Wei B, Presley LL, Brewer S, McPherson M, Lewinski MA, et al. Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota. J Immunol 2008; 180:5843-52; PMID: 18424703.
    • (2008) J Immunol , vol.180 , pp. 5843-5852
    • Fujiwara, D.1    Wei, B.2    Presley, L.L.3    Brewer, S.4    McPherson, M.5    Lewinski, M.A.6
  • 52
    • 77949316299 scopus 로고    scopus 로고
    • Commensal microbiota and CD8+ T cells shape the formation of invariant NKT cells
    • PMID: 20048124
    • Wei B, Wingender G, Fujiwara D, Chen DY, McPherson M, Brewer S, et al. Commensal microbiota and CD8+ T cells shape the formation of invariant NKT cells. J Immunol 2010; 184:1218-26; PMID: 20048124; http://dx.doi.org/10.4049/jimmunol.0902620.
    • (2010) J Immunol , vol.184 , pp. 1218-1226
    • Wei, B.1    Wingender, G.2    Fujiwara, D.3    Chen, D.Y.4    McPherson, M.5    Brewer, S.6
  • 53
    • 0024818822 scopus 로고
    • Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function
    • PMID:2572671
    • Goodman T, Lefrancois L. Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function. J Exp Med 1989; 170:1569-81; PMID:2572671; http://dx.doi.org/10.1084/jem.170.5.1569.
    • (1989) J Exp Med , vol.170 , pp. 1569-1581
    • Goodman, T.1    Lefrancois, L.2
  • 54
    • 0024389095 scopus 로고
    • Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes
    • PMID:2684725
    • Brandtzaeg P, Halstensen TS, Kett K, Krajci P, Kvale D, Rognum TO, et al. Immunobiology and immunopathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes. Gastroenterology 1989; 97:1562-84; PMID:2684725.
    • (1989) Gastroenterology , vol.97 , pp. 1562-1584
    • Brandtzaeg, P.1    Halstensen, T.S.2    Kett, K.3    Krajci, P.4    Kvale, D.5    Rognum, T.O.6
  • 55
    • 0014244928 scopus 로고
    • The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract
    • PMID:4176641
    • Crabbé PA, Bazin H, Eyssen H, Heremans JF. The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract. Int Arch Allergy Appl Immunol 1968; 34:362-75; PMID:4176641; http://dx.doi.org/10.1159/000230130.
    • (1968) Int Arch Allergy Appl Immunol , vol.34 , pp. 362-375
    • Crabbé, P.A.1    Bazin, H.2    Eyssen, H.3    Heremans, J.F.4
  • 56
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • PMID:20576892
    • Hapfelmeier S, Lawson MA, Slack E, Kirundi JK, Stoel M, Heikenwalder M, et al. Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science 2010; 328:1705-9; PMID:20576892; http://dx.doi.org/10.1126/science.1188454.
    • (2010) Science , vol.328 , pp. 1705-1709
    • Hapfelmeier, S.1    Lawson, M.A.2    Slack, E.3    Kirundi, J.K.4    Stoel, M.5    Heikenwalder, M.6
  • 57
    • 2942578705 scopus 로고
    • The response of the lymphatic tissue to the microbial flora. Studies on germfree mice
    • PMID:13966929
    • Bauer H, Horowitz RE, Levenson SM, Popper H. The response of the lymphatic tissue to the microbial flora. Studies on germfree mice. Am J Pathol 1963; 42:471-83; PMID:13966929.
    • (1963) Am J Pathol , vol.42 , pp. 471-483
    • Bauer, H.1    Horowitz, R.E.2    Levenson, S.M.3    Popper, H.4
  • 58
    • 0021699786 scopus 로고
    • Isotypes and specificities of immunoglobulins produced by germ-free mice fed chemically defined ultrafiltered "antigen-free" diet
    • PMID:6083871
    • Hooijkaas H, Benner R, Pleasants JR, Wostmann BS. Isotypes and specificities of immunoglobulins produced by germ-free mice fed chemically defined ultrafiltered "antigen-free" diet. Eur J Immunol 1984; 14:1127-30; PMID:6083871; http://dx.doi.org/10.1002/eji.1830141212.
    • (1984) Eur J Immunol , vol.14 , pp. 1127-1130
    • Hooijkaas, H.1    Benner, R.2    Pleasants, J.R.3    Wostmann, B.S.4
  • 59
    • 0022481149 scopus 로고
    • Autonomous activation of B and T cells in antigen-free mice
    • PMID:2941305
    • Pereira P, Forni L, Larsson EL, Cooper M, Heusser C, Coutinho A. Autonomous activation of B and T cells in antigen-free mice. Eur J Immunol 1986; 16: 685-8; PMID:2941305; http://dx.doi.org/10.1002/eji.1830160616.
    • (1986) Eur J Immunol , vol.16 , pp. 685-688
    • Pereira, P.1    Forni, L.2    Larsson, E.L.3    Cooper, M.4    Heusser, C.5    Coutinho, A.6
  • 60
    • 0024971254 scopus 로고
    • Origin and fate of IgE-bearing lymphocytes. II. Modulation of IgE isotype expression on Peyer's patch cells by feeding with certain bacteria and bacterial cell wall components or by thymectomy
    • PMID:2789249
    • Durkin HG, Chice SM, Gaetjens E, Bazin H, Tarcsay L, Dukor P. Origin and fate of IgE-bearing lymphocytes. II. Modulation of IgE isotype expression on Peyer's patch cells by feeding with certain bacteria and bacterial cell wall components or by thymectomy. J Immunol 1989; 143:1777-83; PMID:2789249.
    • (1989) J Immunol , vol.143 , pp. 1777-1783
    • Durkin, H.G.1    Chice, S.M.2    Gaetjens, E.3    Bazin, H.4    Tarcsay, L.5    Dukor, P.6
  • 61
    • 79953781975 scopus 로고    scopus 로고
    • Antibiotic therapy in inflammatory bowel disease: A systematic review and meta-analysis
    • PMID:21407187
    • Khan KJ, Ullman TA, Ford AC, Abreu MT, Abadir A, Marshall JK, et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol 2011; 106:661-73; PMID:21407187; http://dx.doi.org/10.1038/ajg.2011.72.
    • (2011) Am J Gastroenterol , vol.106 , pp. 661-673
    • Khan, K.J.1    Ullman, T.A.2    Ford, A.C.3    Abreu, M.T.4    Abadir, A.5    Marshall, J.K.6
  • 63
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
    • PMID: 16188921
    • Manichanh C, Rigottier-Gois L, Bonnaud E, Gloux K, Pelletier E, Frangeul L, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 2006; 55:205-11; PMID: 16188921; http://dx.doi.org/10.1136/gut.2005.073817.
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3    Gloux, K.4    Pelletier, E.5    Frangeul, L.6
  • 64
    • 0033000343 scopus 로고    scopus 로고
    • IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
    • PMID:10362650
    • Schultz M, Tonkonogy SL, Sellon RK, Veltkamp C, Godfrey VL, Kwon J, et al. IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation. Am J Physiol 1999; 276: G1461-72; PMID:10362650.
    • (1999) Am J Physiol , vol.276 , pp. 1461-1472
    • Schultz, M.1    Tonkonogy, S.L.2    Sellon, R.K.3    Veltkamp, C.4    Godfrey, V.L.5    Kwon, J.6
  • 65
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10- deficient mice
    • PMID:9784526
    • Sellon RK, Tonkonogy S, Schultz M, Dieleman LA, Grenther W, Balish E, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10- deficient mice. Infect Immun 1998; 66:5224-31; PMID:9784526.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3    Dieleman, L.A.4    Grenther, W.5    Balish, E.6
  • 66
    • 0031012926 scopus 로고    scopus 로고
    • T cell receptor-alpha betadeficient mice fail to develop colitis in the absence of a microbial environment
    • PMID:9006326
    • Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ. T cell receptor-alpha betadeficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol 1997; 150:91-7; PMID:9006326.
    • (1997) Am J Pathol , vol.150 , pp. 91-97
    • Dianda, L.1    Hanby, A.M.2    Wright, N.A.3    Sebesteny, A.4    Hayday, A.C.5    Owen, M.J.6
  • 67
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • PMID:17699621
    • Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 2007; 104:13780-5; PMID:17699621; http://dx.doi.org/10.1073/pnas.0706625104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5    Pace, N.R.6
  • 68
    • 33645019411 scopus 로고    scopus 로고
    • Specificities of the fecal microbiota in inflammatory bowel disease
    • PMID:16432374
    • Sokol H, Seksik P, Rigottier-Gois L, Lay C, Lepage P, Podglajen I, et al. Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis 2006; 12:106-11; PMID:16432374; http://dx.doi.org/10.1097/01.MIB.0000200323.38139.c6.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 106-111
    • Sokol, H.1    Seksik, P.2    Rigottier-Gois, L.3    Lay, C.4    Lepage, P.5    Podglajen, I.6
  • 69
    • 35649026345 scopus 로고    scopus 로고
    • Salmonella enteric serovar typhimurium exploits inflammation to compete with the intestinal microbiota
    • PMID:17760501
    • Stecher B, Robbiani R, Walker AW, Westendorf AM, Barthel M, Kremer M, et al. Salmonella enteric serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol 2007; 5:2177-89; PMID:17760501; http://dx.doi.org/10.1371/journal.pbio.0050244.
    • (2007) PLoS Biol , vol.5 , pp. 2177-2189
    • Stecher, B.1    Robbiani, R.2    Walker, A.W.3    Westendorf, A.M.4    Barthel, M.5    Kremer, M.6
  • 70
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • PMID:17923086
    • Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, et al. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell 2007; 131:33-45; PMID:17923086; http://dx.doi.org/10.1016/j.cell.2007.08.017.
    • (2007) Cell , vol.131 , pp. 33-45
    • Garrett, W.S.1    Lord, G.M.2    Punit, S.3    Lugo-Villarino, G.4    Mazmanian, S.K.5    Ito, S.6
  • 71
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • PMID:20833380
    • Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 2010; 8:292-300; PMID:20833380; http://dx.doi.org/10.1016/j.chom.2010.08.004.
    • (2010) Cell Host Microbe , vol.8 , pp. 292-300
    • Garrett, W.S.1    Gallini, C.A.2    Yatsunenko, T.3    Michaud, M.4    Dubois, A.5    Delaney, M.L.6
  • 72
    • 79957576718 scopus 로고    scopus 로고
    • NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
    • PMID:21565393
    • Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011; 145:745-57; PMID:21565393; http://dx.doi.org/10.1016/j.cell.2011.04.022.
    • (2011) Cell , vol.145 , pp. 745-757
    • Elinav, E.1    Strowig, T.2    Kau, A.L.3    Henao-Mejia, J.4    Thaiss, C.A.5    Booth, C.J.6
  • 73
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • PMID:18509436
    • Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008; 453:620-5; PMID:18509436; http://dx.doi.org/10.1038/nature07008.
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 74
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
    • PMID:14691478
    • Kelly D, Campbell JI, King TP, Grant G, Jansson EA, Coutts AG, et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol 2004; 5:104-12; PMID:14691478; http://dx.doi.org/10.1038/ni1018.
    • (2004) Nat Immunol , vol.5 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3    Grant, G.4    Jansson, E.A.5    Coutts, A.G.6
  • 75
    • 33747777758 scopus 로고    scopus 로고
    • PPARgamma as a new therapeutic target in inflammatory bowel diseases
    • PMID:16905700
    • Dubuquoy L, Rousseaux C, Thuru X, Peyrin-Biroulet L, Romano O, Chavatte P, et al. PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut 2006; 55:1341-9; PMID:16905700; http://dx.doi.org/10.1136/gut.2006.093484.
    • (2006) Gut , vol.55 , pp. 1341-1349
    • Dubuquoy, L.1    Rousseaux, C.2    Thuru, X.3    Peyrin-Biroulet, L.4    Romano, O.5    Chavatte, P.6
  • 76
    • 70350666634 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
    • PMID:19865172
    • Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 2009; 461:1282-6; PMID:19865172; http://dx.doi.org/10.1038/nature08530.
    • (2009) Nature , vol.461 , pp. 1282-1286
    • Maslowski, K.M.1    Vieira, A.T.2    Ng, A.3    Kranich, J.4    Sierro, F.5    Yu, D.6
  • 77
    • 77953486362 scopus 로고    scopus 로고
    • Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis
    • PMID: 20498021
    • Feng T, Wang L, Schoeb TR, Elson CO, Cong Y. Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis. J Exp Med 2010; 207:1321-32; PMID: 20498021; http://dx.doi.org/10.1084/jem.20092253.
    • (2010) J Exp Med , vol.207 , pp. 1321-1332
    • Feng, T.1    Wang, L.2    Schoeb, T.R.3    Elson, C.O.4    Cong, Y.5
  • 78
    • 32544454825 scopus 로고    scopus 로고
    • Non-HLA associations with autoimmune diseases
    • PMID:16483921
    • Serrano NC, Millan P, Páez MC. Non-HLA associations with autoimmune diseases. Autoimmun Rev 2006; 5:209-14; PMID:16483921; http://dx.doi.org/10.1016/j.autrev.2005.06.009.
    • (2006) Autoimmun Rev , vol.5 , pp. 209-214
    • Serrano, N.C.1    Millan, P.2    Páez, M.C.3
  • 79
    • 0029128706 scopus 로고
    • Concordance rates of insulin dependent diabetes mellitus: A population based study of young Danish twins
    • PMID:7580548
    • Kyvik KO, Green A, Beck-Nielsen H. Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins. BMJ 1995; 311:913-7; PMID:7580548; http://dx.doi.org/10.1136/bmj.311.7010.913.
    • (1995) BMJ , vol.311 , pp. 913-917
    • Kyvik, K.O.1    Green, A.2    Beck-Nielsen, H.3
  • 80
    • 49049110038 scopus 로고    scopus 로고
    • Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis
    • PMID:18671318
    • Edwards CJ. Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis. J Rheumatol 2008; 35:1477-14797; PMID:18671318.
    • (2008) J Rheumatol , vol.35 , pp. 1477-14797
    • Edwards, C.J.1
  • 81
    • 23044501161 scopus 로고    scopus 로고
    • Early arthritis and infection
    • PMID:15956840
    • Leirisalo-Repo M. Early arthritis and infection. Curr Opin Rheumatol 2005; 17:433-9; PMID:15956840; http://dx.doi.org/10.1097/01.bor.0000166388.47604.8b.
    • (2005) Curr Opin Rheumatol , vol.17 , pp. 433-439
    • Leirisalo-Repo, M.1
  • 83
    • 0027947416 scopus 로고
    • Role of the bowel flora for development of immunity to hsp 65 and arthritis in three experimental models
    • PMID:7997855
    • Björk J, Kleinau S, Midtvedt T, Klareskog L, Smedegård G. Role of the bowel flora for development of immunity to hsp 65 and arthritis in three experimental models. Scand J Immunol 1994; 40: 648-52; PMID:7997855; http://dx.doi.org/10.1111/j.1365-3083.1994.tb03518.x.
    • (1994) Scand J Immunol , vol.40 , pp. 648-652
    • Björk, J.1    Kleinau, S.2    Midtvedt, T.3    Klareskog, L.4    Smedegård, G.5
  • 84
    • 38149048556 scopus 로고    scopus 로고
    • Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
    • PMID:18060042
    • Abdollahi-Roodsaz S, Joosten LA, Koenders MI, Devesa I, Roelofs MF, Radstake TR, et al. Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J Clin Invest 2008; 118:205-16; PMID:18060042; http://dx.doi.org/10.1172/JCI32639.
    • (2008) J Clin Invest , vol.118 , pp. 205-216
    • Abdollahi-Roodsaz, S.1    Joosten, L.A.2    Koenders, M.I.3    Devesa, I.4    Roelofs, M.F.5    Radstake, T.R.6
  • 85
    • 80052829380 scopus 로고    scopus 로고
    • Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes
    • PMID:21646390
    • Badami E, Sorini C, Coccia M, Usuelli V, Molteni L, Bolla AM, et al. Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes. Diabetes 2011; 60: 2120-4; PMID:21646390; http://dx.doi.org/10.2337/db10-1201.
    • (2011) Diabetes , vol.60 , pp. 2120-2124
    • Badami, E.1    Sorini, C.2    Coccia, M.3    Usuelli, V.4    Molteni, L.5    Bolla, A.M.6
  • 86
    • 0037136537 scopus 로고    scopus 로고
    • The effect of infections on susceptibility to autoimmune and allergic diseases
    • PMID:12239261
    • Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002; 347:911-20; PMID:12239261; http://dx.doi.org/10.1056/NEJMra020100.
    • (2002) N Engl J Med , vol.347 , pp. 911-920
    • Bach, J.F.1
  • 87
    • 63249107452 scopus 로고    scopus 로고
    • Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms
    • PMID:19185542
    • Zipris D. Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms. Clin Immunol 2009; 131:11-23; PMID:19185542; http://dx.doi.org/10.1016/j.clim.2008.12.011.
    • (2009) Clin Immunol , vol.131 , pp. 11-23
    • Zipris, D.1
  • 88
    • 0027166934 scopus 로고
    • NOD mouse colonies around the world-recent facts and figures
    • PMID: 8517916
    • Pozzilli P, Signore A, Williams AJ, Beales PE. NOD mouse colonies around the world-recent facts and figures. Immunol Today 1993; 14:193-6; PMID: 8517916; http://dx.doi.org/10.1016/0167-5699(93)90160-M.
    • (1993) Immunol Today , vol.14 , pp. 193-196
    • Pozzilli, P.1    Signore, A.2    Williams, A.J.3    Beales, P.E.4
  • 90
    • 54549122338 scopus 로고    scopus 로고
    • Innate immunity and intestinal microbiota in the development of Type 1 diabetes
    • PMID:18806780
    • Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008; 455:1109-13; PMID:18806780; http://dx.doi.org/10.1038/nature07336.
    • (2008) Nature , vol.455 , pp. 1109-1113
    • Wen, L.1    Ley, R.E.2    Volchkov, P.Y.3    Stranges, P.B.4    Avanesyan, L.5    Stonebraker, A.C.6
  • 91
    • 79960983258 scopus 로고    scopus 로고
    • Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
    • PMID:21709219
    • Kriegel MA, Sefik E, Hill JA, Wu HJ, Benoist C, Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A 2011; 108:11548-53; PMID:21709219; http://dx.doi.org/10.1073/pnas.1108924108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11548-11553
    • Kriegel, M.A.1    Sefik, E.2    Hill, J.A.3    Wu, H.J.4    Benoist, C.5    Mathis, D.6
  • 92
    • 80052517464 scopus 로고    scopus 로고
    • Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice
    • PMID:21380595
    • Alam C, Bittoun E, Bhagwat D, Valkonen S, Saari A, Jaakkola U, et al. Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice. Diabetologia 2011; 54:1398-406; PMID:21380595; http://dx.doi.org/10.1007/s00125-011-2097-5.
    • (2011) Diabetologia , vol.54 , pp. 1398-1406
    • Alam, C.1    Bittoun, E.2    Bhagwat, D.3    Valkonen, S.4    Saari, A.5    Jaakkola, U.6
  • 93
    • 79952142398 scopus 로고    scopus 로고
    • The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions
    • PMID:21364875
    • King C, Sarvetnick N. The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions. PLoS One 2011; 6: e17049; PMID:21364875; http://dx.doi.org/10.1371/journal.pone.0017049.
    • (2011) PLoS One , vol.6 , pp. 17049
    • King, C.1    Sarvetnick, N.2
  • 94
    • 77249096486 scopus 로고    scopus 로고
    • Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    • PMID:19841183
    • Ochoa-Repáraz J, Mielcarz DW, Ditrio LE, Burroughs AR, Foureau DM, Haque-Begum S, et al. Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis. J Immunol 2009; 183:6041-50; PMID:19841183; http://dx.doi.org/10.4049/jimmunol.0900747.
    • (2009) J Immunol , vol.183 , pp. 6041-6050
    • Ochoa-Repáraz, J.1    Mielcarz, D.W.2    Ditrio, L.E.3    Burroughs, A.R.4    Foureau, D.M.5    Haque-Begum, S.6
  • 95
    • 79952748674 scopus 로고    scopus 로고
    • Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • PMID:20660719
    • Lee YK, Menezes JS, Umesaki Y, Mazmanian SK. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2011; 108(Suppl 1):4615-22; PMID:20660719; http://dx.doi.org/10.1073/pnas.1000082107.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.1 SUPPL. , pp. 4615-4622
    • Lee, Y.K.1    Menezes, J.S.2    Umesaki, Y.3    Mazmanian, S.K.4
  • 96
    • 77958119730 scopus 로고    scopus 로고
    • Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    • PMID:20817872
    • Ochoa-Repáraz J, Mielcarz DW, Ditrio LE, Burroughs AR, Begum-Haque S, Dasgupta S, et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J Immunol 2010; 185: 4101-8; PMID:20817872; http://dx.doi.org/10.4049/jimmunol.1001443.
    • (2010) J Immunol , vol.185 , pp. 4101-4108
    • Ochoa-Repáraz, J.1    Mielcarz, D.W.2    Ditrio, L.E.3    Burroughs, A.R.4    Begum-Haque, S.5    Dasgupta, S.6
  • 97
    • 77955913743 scopus 로고    scopus 로고
    • A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease
    • PMID:20531465
    • Ochoa-Repáraz J, Mielcarz DW, Wang Y, Begum-Haque S, Dasgupta S, Kasper DL, et al. A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease. Mucosal Immunol 2010; 3:487-95; PMID:20531465; http://dx.doi.org/10.1038/mi.2010.29.
    • (2010) Mucosal Immunol , vol.3 , pp. 487-495
    • Ochoa-Repáraz, J.1    Mielcarz, D.W.2    Wang, Y.3    Begum-Haque, S.4    Dasgupta, S.5    Kasper, D.L.6
  • 98
    • 77954827808 scopus 로고    scopus 로고
    • Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora
    • PMID:21326918
    • Ochoa-Repáraz J, Mielcarz DW, Haque-Begum S, Kasper LH. Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora. Gut Microbes 2010; 1:103-8; PMID:21326918; http://dx.doi.org/10.4161/gmic.1.2.11515.
    • (2010) Gut Microbes , vol.1 , pp. 103-108
    • Ochoa-Repáraz, J.1    Mielcarz, D.W.2    Haque-Begum, S.3    Kasper, L.H.4
  • 99
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • PMID:20126401
    • Lavasani S, Dzhambazov B, Nouri M, Fåk F, Buske S, Molin G, et al. A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS One 2010; 5:e9009; PMID:20126401; http://dx.doi.org/10.1371/journal.pone.0009009.
    • (2010) PLoS One , vol.5 , pp. 9009
    • Lavasani, S.1    Dzhambazov, B.2    Nouri, M.3    Fåk, F.4    Buske, S.5    Molin, G.6
  • 100
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the aire protein
    • PMID:12376594
    • Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002; 298:1395-401; PMID:12376594; http://dx.doi.org/10.1126/science.1075958.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1    Venanzi, E.S.2    Klein, L.3    Chen, Z.4    Berzins, S.P.5    Turley, S.J.6
  • 101
    • 36749013631 scopus 로고    scopus 로고
    • Dangerfree autoimmune disease in Aire-deficient mice
    • PMID: 17991771
    • Gray DH, Gavanescu I, Benoist C, Mathis D. Dangerfree autoimmune disease in Aire-deficient mice. Proc Natl Acad Sci U S A 2007; 104:18193-8; PMID: 17991771; http://dx.doi.org/10.1073/pnas.0709160104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18193-18198
    • Gray, D.H.1    Gavanescu, I.2    Benoist, C.3    Mathis, D.4
  • 102
    • 0033153482 scopus 로고    scopus 로고
    • The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice
    • PMID:10352243
    • Maldonado MA, Kakkanaiah V, MacDonald GC, Chen F, Reap EA, Balish E, et al. The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice. J Immunol 1999; 162:6322-30; PMID:10352243.
    • (1999) J Immunol , vol.162 , pp. 6322-6330
    • Maldonado, M.A.1    Kakkanaiah, V.2    Macdonald, G.C.3    Chen, F.4    Reap, E.A.5    Balish, E.6
  • 103
    • 51849125587 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease
    • PMID:18716662
    • Hase K, Takahashi D, Ebisawa M, Kawano S, Itoh K, Ohno H. Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease. PLoS One 2008; 3:e3033; PMID:18716662; http://dx.doi.org/10.1371/journal.pone.0003033.
    • (2008) PLoS One , vol.3 , pp. 3033
    • Hase, K.1    Takahashi, D.2    Ebisawa, M.3    Kawano, S.4    Itoh, K.5    Ohno, H.6
  • 104
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: A metagenomic analysis in humanized gnotobiotic mice
    • PMID:20368178
    • Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009; 1:6ra14; PMID:20368178; http://dx.doi.org/10.1126/scitranslmed.3000322.
    • (2009) Sci Transl Med , vol.1 , pp. 14
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3    Rey, F.E.4    Knight, R.5    Gordon, J.I.6
  • 105
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • PMID:20679230
    • De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010; 107:14691-6; PMID:20679230; http://dx.doi.org/10.1073/pnas.1005963107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14691-14696
    • de Filippo, C.1    Cavalieri, D.2    Di Paola, M.3    Ramazzotti, M.4    Poullet, J.B.5    Massart, S.6
  • 106
    • 77953302950 scopus 로고    scopus 로고
    • Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change
    • PMID:20547977
    • Alam C, Valkonen S, Palagani V, Jalava J, Eerola E, Hänninen A. Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change. Diabetes 2010; 59:2237-46; PMID:20547977; http://dx.doi.org/10.2337/db10-0147.
    • (2010) Diabetes , vol.59 , pp. 2237-2246
    • Alam, C.1    Valkonen, S.2    Palagani, V.3    Jalava, J.4    Eerola, E.5    Hänninen, A.6
  • 107
    • 11144256980 scopus 로고    scopus 로고
    • Development of allergic airway disease in mice following antibiotic therapy and fungal microbiota increase: Role of host genetics, antigen, and interleukin-13
    • PMID:15618138
    • Noverr MC, Falkowski NR, McDonald RA, McKenzie AN, Huffnagle GB. Development of allergic airway disease in mice following antibiotic therapy and fungal microbiota increase: role of host genetics, antigen, and interleukin-13. Infect Immun 2005; 73: 30-8; PMID:15618138; http://dx.doi.org/10.1128/IAI.73.1.30-38.2005.
    • (2005) Infect Immun , vol.73 , pp. 30-38
    • Noverr, M.C.1    Falkowski, N.R.2    McDonald, R.A.3    McKenzie, A.N.4    Huffnagle, G.B.5
  • 108
    • 40349113425 scopus 로고    scopus 로고
    • The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis
    • PMID:18248093
    • McKenna P, Hoffmann C, Minkah N, Aye PP, Lackner A, Liu Z, et al. The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis. PLoS Pathog 2008; 4:e20; PMID:18248093; http://dx.doi.org/10.1371/journal.ppat.0040020.
    • (2008) PLoS Pathog , vol.4 , pp. 20
    • McKenna, P.1    Hoffmann, C.2    Minkah, N.3    Aye, P.P.4    Lackner, A.5    Liu, Z.6
  • 109
    • 33748415364 scopus 로고    scopus 로고
    • Factors influencing the composition of the intestinal microbiota in early infancy
    • PMID:16882802
    • Penders J, Thijs C, Vink C, Stelma FF, Snijders B, Kummeling I, et al. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 2006; 118:511-21; PMID:16882802; http://dx.doi.org/10.1542/peds.2005-2824.
    • (2006) Pediatrics , vol.118 , pp. 511-521
    • Penders, J.1    Thijs, C.2    Vink, C.3    Stelma, F.F.4    Snijders, B.5    Kummeling, I.6
  • 110
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • PMID:20566857
    • Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A 2010; 107:11971-5; PMID:20566857; http://dx.doi.org/10.1073/pnas.1002601107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3    Magris, M.4    Hidalgo, G.5    Fierer, N.6
  • 111
    • 84655169944 scopus 로고    scopus 로고
    • Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization (FISH)
    • PMID:21497661
    • Bezirtzoglou E, Tsiotsias A, Welling GW. Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization (FISH). Anaerobe 2011; 17:478-82; PMID:21497661; http://dx.doi.org/10.1016/j.anaerobe.2011.03.009.
    • (2011) Anaerobe , vol.17 , pp. 478-482
    • Bezirtzoglou, E.1    Tsiotsias, A.2    Welling, G.W.3
  • 112
    • 12844251441 scopus 로고    scopus 로고
    • Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by realtime PCR
    • PMID:15668012
    • Penders J, Vink C, Driessen C, London N, Thijs C, Stobberingh EE. Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by realtime PCR. FEMS Microbiol Lett 2005; 243:141-7; PMID:15668012; http://dx.doi.org/10.1016/j.femsle.2004.11.052.
    • (2005) FEMS Microbiol Lett , vol.243 , pp. 141-147
    • Penders, J.1    Vink, C.2    Driessen, C.3    London, N.4    Thijs, C.5    Stobberingh, E.E.6
  • 113
    • 0020052321 scopus 로고
    • The microbial ecology of the large bowel of breast-fed and formula-fed infants during the first year of life
    • PMID:7143428
    • Stark PL, Lee A. The microbial ecology of the large bowel of breast-fed and formula-fed infants during the first year of life. J Med Microbiol 1982; 15:189-203; PMID:7143428; http://dx.doi.org/10.1099/00222615-15-2-189.
    • (1982) J Med Microbiol , vol.15 , pp. 189-203
    • Stark, P.L.1    Lee, A.2
  • 114
    • 0034076597 scopus 로고    scopus 로고
    • Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods
    • PMID:10630441
    • Harmsen HJ, Wildeboer-Veloo AC, Raangs GC, Wagendorp AA, Klijn N, Bindels JG, et al. Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J Pediatr Gastroenterol Nutr 2000; 30:61-7; PMID:10630441; http://dx.doi.org/10.1097/00005176-200001000-00019.
    • (2000) J Pediatr Gastroenterol Nutr , vol.30 , pp. 61-67
    • Harmsen, H.J.1    Wildeboer-Veloo, A.C.2    Raangs, G.C.3    Wagendorp, A.A.4    Klijn, N.5    Bindels, J.G.6
  • 115
    • 0020562186 scopus 로고
    • Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants
    • PMID:6412205
    • Yoshioka H, Iseki K, Fujita K. Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants. Pediatrics 1983; 72:317-21; PMID:6412205.
    • (1983) Pediatrics , vol.72 , pp. 317-321
    • Yoshioka, H.1    Iseki, K.2    Fujita, K.3
  • 116
    • 33645219404 scopus 로고    scopus 로고
    • Caesarean section delivery and the risk of allergic disorders in childhood
    • PMID:16297144
    • Renz-Polster H, David MR, Buist AS, Vollmer WM, O'Connor EA, Frazier EA, et al. Caesarean section delivery and the risk of allergic disorders in childhood. Clin Exp Allergy 2005; 35:1466-72; PMID:16297144; http://dx.doi.org/10.1111/j.1365-2222.2005.02356.x.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1466-1472
    • Renz-Polster, H.1    David, M.R.2    Buist, A.S.3    Vollmer, W.M.4    O'Connor, E.A.5    Frazier, E.A.6
  • 117
    • 33748847345 scopus 로고    scopus 로고
    • Mode of delivery is associated with asthma and allergy occurrences in children
    • PMID: 16242961
    • Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol 2006; 16:341-6; PMID: 16242961; http://dx.doi.org/10.1016/j.annepidem.2005.06.054.
    • (2006) Ann Epidemiol , vol.16 , pp. 341-346
    • Salam, M.T.1    Margolis, H.G.2    McConnell, R.3    McGregor, J.A.4    Avol, E.L.5    Gilliland, F.D.6
  • 118
    • 85046980153 scopus 로고    scopus 로고
    • Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children
    • PMID:21637025
    • Decker E, Hornef M, Stockinger S. Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. Gut Microbes 2011; 2:91-8; PMID:21637025; http://dx.doi.org/10.4161/gmic.2.2.15414.
    • (2011) Gut Microbes , vol.2 , pp. 91-98
    • Decker, E.1    Hornef, M.2    Stockinger, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.