Risk of obesity and type 2 diabetes with tumor necrosis factor-α 308G/A gene polymorphism in metabolic syndrome and coronary artery disease subjects

Molecular and Cellular Biochemistry

Volumn 360, Issue 1-2, 2012, Pages 1-7

  Sobti, Ranbir Chander ^a   Kler, Rupinder ^a   Sharma, Yash Paul ^b   Talwar, Kewal Krishan ^b   Singh, Neha ^a  

^a PANJAB UNIVERSITY   (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Coronary artery disease; Metabolic syndrome; Obesity; Polymerase chain reaction amplification refractory mutation system; Tumor necrosis factor alpha; Type 2 diabetes

Indexed keywords

GENOMIC DNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DNA POLYMORPHISM; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POLYMERASE CHAIN REACTION; RISK FACTOR; SEX DIFFERENCE;

ADULT; ALLELES; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GENOTYPE; HUMANS; INDIA; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; REGRESSION ANALYSIS; RISK FACTORS; SEQUENCE ANALYSIS, DNA; SEX FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83555176087     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0917-z     Document Type: Article

References (21)

1. C Qi PH Pekala 2000 Tumor necrosis factor-alpha-induced insulin resistance in adipocytes Proc Soc Exp Biol Med 223 2 128 135 10654615 10.1046/j.1525-1373.2000.22318.x 1:CAS:528:DC%2BD3cXltVaksr8%3D (Pubitemid 30339434)
2. S Romeo F Sentinelli F Capici M Arca A Berni E Vecci UD Mario MG Baroni 2001 The G-308A variant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution BMC Med Genet 2 10 11570978 10.1186/1471-2350-2-10 1:STN:280:DC%2BD3szhslCmtQ%3D%3D (Pubitemid 38692946)
3. C Beste O Güntürkün BT Baune K Domschke M Falkenstein C Konrad 2011 Double dissociated effects of the functional TNF-α -308G/A polymorphism on processes of cognitive control Neuropsychologia 49 2 196 202 21130787 10.1016/j.neuropsychologia.2010.11.037
4. L Ghazouani SBH Khalifa N Abboud F Addad AB Khalfallah N Brahmin M Mediouni WY Almauvi T Mahjoub 2009 308 G>A and -1031 T>C tumor necrosis factor gene polymorphisms in Tunisian patients with Coronary artery disease Clin Chem Lab Med 47 10 1247 1251 19803813 10.1515/CCLM.2009.287 1:CAS:528:DC%2BD1MXhtlyjs73E
5. R Feinstein H Kanety MZ Papa B Lunenfeld A Karasik 1993 Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates J Biol Chem 268 35 26055 26058 8253716 1:CAS:528:DyaK3sXmsVOksbw%3D
6. GS Hotamisligil A Budavari D Murray BM Spiegelman 1994 Reduced tyrosine kinase activity of the insulin receptor in obesity- diabetes. Central role of tumor necrosis factor-α J Clin Invest 94 4 1543 1549 7523453 10.1172/JCI117495 1:CAS:528:DyaK2cXmt1OrtL8%3D
7. KT Uysal SM Wiesbrock MW Marino GS Hotamisligil 1997 Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function Nature 389 6651 610 614 9335502 10.1038/39335 1:CAS:528:DyaK2sXmslWgu7k%3D (Pubitemid 27446179)
8. GS Hotamisligil P Peraldi A Budavari R Ellis MF White BM Spiegelman 1996 IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance Science 271 5249 665 668 8571133 10.1126/science.271.5249.665 1:CAS:528:DyaK28XptVyhtQ%3D%3D (Pubitemid 26052915)
9. DE Moller 2000 Potential role of TNF-α in pathogenesis of IR and T2DM Trends Endocrinol Metab 11 6 212 217 10878750 10.1016/S1043-2760(00)00272-1 1:CAS:528:DC%2BD3cXks12rtbo%3D (Pubitemid 30603166)
10. Ghaderian SM, Akbarzadeh Najar R, Tabatabaei Panah AS (2010) Tumor necrosis factor-α: investigation of gene polymorphism and regulation of TACE-TNF-α system in patients with acute myocardial infarction. Mol Biol Rep. doi: 10.1007/s11033-010-0641-x
11. YT Joffe L Vander Merve M Carstens M Collins C Jennings NS Levitt EV Lambert JH Goedacke 2010 Tumor necrosis factor-alpha -308G/A polymorphism modulates the relationship between dietary intake, fat intake, serum lipids and obesity in black south African women J Nutr 140 5 901 907 20335630 10.3945/jn.109.109355 1:CAS:528:DC%2BC3cXlsVWrsLo%3D
12. MF Taylor 2001 Target validation and functional analyses using antisense oligonucleotides Expert Opin Ther Target 5 3 297 301 10.1517/14728222.5.3.297 1:CAS:528:DC%2BD3MXlt1aqu7w%3D
13. Expert panel on detection, evaluation and treatment of high blood pressure, cholesterol in adults (2001) Executive summary of the third report of national cholesterol education panel (NCEP) and expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA 285(19):2486-2497
14. SL McCarron S Edwards PR Evans R Gibbs DP Dearnaley A Dowe C Southgate DF Easton RA Eeles WM Howell 2002 Influence of cytokine gene polymorphisms on the development of prostate cancer Cancer Res 62 12 3369 3372 12067976 1:CAS:528:DC%2BD38XkslWqsLs%3D (Pubitemid 34651380)
15. HE Lebovitz 1999 Type 2 diabetes: An overview Clin Chem 45 8 pt2 1339 1345 10430816 1:CAS:528:DyaK1MXltFGnurk%3D (Pubitemid 29422073)
16. BD Mitchell CM Kammerer MC Mahaney J Blangero AG Comuzzie LD Atwood SM Haffner MP Stern JW MacCluer 1996 Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures Arterioscler Thromb Vasc Biol 16 2 281 288 8620344 10.1161/01.ATV.16.2.281 1:STN:280:DyaK287oslOntg%3D%3D (Pubitemid 26056248)
17. J Bidwell L Keen G Gallagher R Kimberly T Huizinga MF McDermott J Oksenberg J McNicholl F Pociot C Hardt S D'Alfonso 2001 Cytokine gene polymorphism in human disease: on-line databases, supplement 1 Genes Immun 2 2 61 70 11393658 10.1038/sj.gene.6363733 1:CAS:528:DC%2BD3MXjtFKntbk%3D (Pubitemid 33674230)
18. B Dalziel AK Gosby RM Richman JM Bryson ID Caterson 2002 Association of the TNF-α -308 G/A promoter polymorphism with insulin resistance in obesity Obes Res 10 5 401 407 12006640 10.1038/oby.2002.55 1:CAS:528: DC%2BD38Xmtlymtbk%3D (Pubitemid 135688251)
19. SC Sookoian C González CJ Pirola 2005 Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome Obes Res 13 12 2122 2131 16421346 10.1038/oby.2005.263
20. B Da Silva SM Gapstur YH Achenbach TS Schuh TJ Kotlar K Liu WL Lowe Jr 2000 Lack of association between the -308 polymorphism of the tumor necrosis factor-alpha gene and the insulin resistance syndrome J Investig Med 48 4 236 244 1:CAS:528:DC%2BD3cXntFOmtLs%3D
21. MM Elahi A Gilmour BM Matata SS Mastana 2008 A variant of position - 308 of the Tumour necrosis factor alpha gene promoter and the risk of coronary heart disease Heart Lung Circ 17 1 14 18 17581788 10.1016/j.hlc.2007.05.009 1:CAS:528:DC%2BD1cXislCnsrc%3D (Pubitemid 350246341)