Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder

Translational Psychiatry

Volumn 4, Issue , 2014, Pages

  Carvalho, L A ^a   Bergink, V ^b   Sumaski, L ^c   Wijkhuijs, J ^b   Hoogendijk, W J ^b   Birkenhager, T K ^b   Drexhage, H A ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Biomarkers; Chronic stress; Genomics; Immunology; Neuroendocrinology

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; BCL2 RELATED PROTEIN A1; CD9 ANTIGEN; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; DUAL SPECIFICITY PHOSPHATASE 2; EARLY GROWTH RESPONSE FACTOR 3; ERYTHROCYTE MEMBRANE PROTEIN 1; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; PENTRAXIN 3; PROTEIN CDC42; TRANSCRIPTION FACTOR MAFF; TRANSCRIPTION FACTOR PU 1; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; VASCULOTROPIN; GLUCOCORTICOID RECEPTOR; ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE DERIVATIVE; CHEMOKINE; CYTOKINE; HALOPERIDOL; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TETRACYCLIC ANTIDEPRESSANT AGENT; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; DSM-IV-TR; FEMALE; GENE ACTIVATION; GENE CLUSTER; GENE EXPRESSION; HAMILTON SCALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; MAJOR DEPRESSION; MALE; MELANCHOLIA; MIDDLE AGED; MONOCYTE; MOOD DISORDER; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; AGED; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; VERY ELDERLY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC PARAMETERS; GLUCOCORTICOID RECEPTOR ALPHA GLUCOCORTICOID RECEPTOR BETA EXPRESSION RATIO; HOSPITAL PATIENT; IMMUNOREGULATION; MAJOR CLINICAL STUDY; MENTAL PATIENT; NEUROIMMUNOLOGY; PSYCHOPHARMACOTHERAPY; QUANTITATIVE ANALYSIS; SERUM;

ADULT; AGED; AGED, 80 AND OVER; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; MONOCYTES; RECEPTORS, GLUCOCORTICOID;

EID: 84893345725     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2013.118     Document Type: Article

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