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Volumn 55, Issue 9, 2003, Pages 497-504

Putting the Brake on Inflammatory Responses: The Role of Glucocorticoids

Author keywords

Activator protein 1 (AP 1); Glucocorticoid receptor (GR); Glucocorticoids (GC); Nuclear factor B (NF B); Toll like receptors (TLRs)

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

EID: 0344012614     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540310001642072     Document Type: Review
Times cited : (52)

References (59)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., Murphy, K. M., and Sher, A. (1996) Functional diversity of helper T lymphocytes. Nature 383(6603), 787-793.
    • (1996) Nature , vol.383 , Issue.6603 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 2
    • 0035971432 scopus 로고    scopus 로고
    • AP-1 in mouse development and tumorigenesis
    • Jochum, W., Passegue, E., and Wagner, E, F. (2001) AP-1 in mouse development and tumorigenesis. Oncogene 20(19) 2401-2412.
    • (2001) Oncogene , vol.20 , Issue.19 , pp. 2401-2412
    • Jochum, W.1    Passegue, E.2    Wagner, E.F.3
  • 3
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian, E., and Karin, M. (2001 AP-1 in cell proliferation and survival. Oncogene 20(19), 2390-2400.
    • (2001) Oncogene , vol.20 , Issue.19 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 4
    • 17344362761 scopus 로고    scopus 로고
    • Signaling by dual specificity kinases
    • Reviews
    • Dhanasekaran, N., and Premkumar Reddy, E. (1998) Signaling by dual specificity kinases. Oncogene 17(11 Reviews), 1447-1455.
    • (1998) Oncogene , vol.17 , Issue.11 , pp. 1447-1455
    • Dhanasekaran, N.1    Premkumar Reddy, E.2
  • 5
    • 0029808748 scopus 로고
    • Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
    • Whitmarsh, A. J., and Davis, R. J. (1966) Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J. Mol. Med. 74(10), 589-607.
    • (1966) J. Mol. Med. , vol.74 , Issue.10 , pp. 589-607
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 6
    • 0029937701 scopus 로고    scopus 로고
    • Phosphorylation of c-Fos at the C-terminus enhances its transforming activity
    • Chen, R. H., Juo, P. C., Curran, T., and Blenis, J. (1996) Phosphorylation of c-Fos at the C-terminus enhances its transforming activity. Oncogene 12(7), 1493-1502.
    • (1996) Oncogene , vol.12 , Issue.7 , pp. 1493-1502
    • Chen, R.H.1    Juo, P.C.2    Curran, T.3    Blenis, J.4
  • 7
    • 0030901946 scopus 로고    scopus 로고
    • Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain
    • Skinner, M., Qu, S., Moore, C., and Wisdom, R. (1997) Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain. Mol. Cell. Biol. 17(5), 2372-2380.
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.5 , pp. 2372-2380
    • Skinner, M.1    Qu, S.2    Moore, C.3    Wisdom, R.4
  • 8
    • 0028108504 scopus 로고
    • Regulation of Fra-1 and Fra-2 phosphorylation differs during the cell cycle of fibroblasts and phosphorylation in vitro by MAP kinase affects DNA binding activity
    • Gruda, M., C., Kovary, K., Metz, R., and Bravo, R. (1994) Regulation of Fra-1 and Fra-2 phosphorylation differs during the cell cycle of fibroblasts and phosphorylation in vitro by MAP kinase affects DNA binding activity. Oncogene 9(9), 2537-2547.
    • (1994) Oncogene , vol.9 , Issue.9 , pp. 2537-2547
    • Gruda, M.1    Kovary, C.2    Metz, K.3    Bravo, R.R.4
  • 9
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and Karin, M. (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta. 1072(2-3), 129-157.
    • (1991) Biochim. Biophys. Acta , vol.1072 , Issue.2-3 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 10
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin, A. S., Jr. (1996) The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 14, 649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 12
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S., May, M. J., and Kopp, E. B. (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 13
    • 0034745420 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p 100
    • Xiao, G., Harhaj, E. W., and Sun, S. C. (2001) NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p 100. Mol. Cell 7(2), 401-409.
    • (2001) Mol. Cell , vol.7 , Issue.2 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.C.3
  • 14
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong, H., Voll, R. E., and Ghosh, S. (1998) Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1(5), 661-671.
    • (1998) Mol. Cell , vol.1 , Issue.5 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 15
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
    • Karin, M., and Ben-Neriah, Y. (2000) Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 18, 621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 16
    • 0028967819 scopus 로고
    • Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B
    • Arenzana-Seisdedos, F., Thompson, J., Rodriguez, M. S., Bachelerie, F., Thomas, D., and Hay, R. T. (1995) Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol. Cell. Biol. 15(5), 2689-2696.
    • (1995) Mol. Cell. Biol. , vol.15 , Issue.5 , pp. 2689-2696
    • Arenzana-Seisdedos, F.1    Thompson, J.2    Rodriguez, M.S.3    Bachelerie, F.4    Thomas, D.5    Hay, R.T.6
  • 17
    • 0030899121 scopus 로고    scopus 로고
    • I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity
    • Whiteside, S. T., Epinat, J. C., Rice, N. R., and Israel, A. (1997) I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity. EMBO J. 16(6), 1413-1426.
    • (1997) EMBO J. , vol.16 , Issue.6 , pp. 1413-1426
    • Whiteside, S.T.1    Epinat, J.C.2    Rice, N.R.3    Israel, A.4
  • 18
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh, S., and Karin, M. (2002) Missing pieces in the NF-kappaB puzzle. Cell 109(Suppl), S81-S96.
    • (2002) Cell , vol.109 , pp. S81-S96
    • Ghosh, S.1    Karin, M.2
  • 19
    • 0027471762 scopus 로고
    • v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence
    • Mosialos, G., and Gilmore, T. D. (1993) v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence. Oncogene 8(3), 721-730.
    • (1993) Oncogene , vol.8 , Issue.3 , pp. 721-730
    • Mosialos, G.1    Gilmore, T.D.2
  • 21
    • 13944253118 scopus 로고    scopus 로고
    • Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway
    • Leitges, M., et al. (2001) Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway. Mol. Cell 8(4), 771-780.
    • (2001) Mol. Cell , vol.8 , Issue.4 , pp. 771-780
    • Leitges, M.1
  • 23
    • 0034693133 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
    • Wang, D., Westerheide. S. D., Hanson, J. L., and Baldwin, A. S., Jr. (2000) Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J. Biol. Chem. 275(42), 32592-32597.
    • (2000) J. Biol. Chem. , vol.275 , Issue.42 , pp. 32592-32597
    • Wang, D.1    Westerheide, S.D.2    Hanson, J.L.3    Baldwin, A.S.4
  • 24
    • 0030827057 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha and interleukin 1 signalling: Do MAPKK kinases connect it all?
    • Eder, J. (1997) Tumour necrosis factor alpha and interleukin 1 signalling: do MAPKK kinases connect it all? Trends Pharmacol. Sci. 18(9), 319-322.
    • (1997) Trends Pharmacol. Sci. , vol.18 , Issue.9 , pp. 319-322
    • Eder, J.1
  • 25
    • 0023794190 scopus 로고
    • Multiple and cooperative trans-activation domains of the human glucocorticoid receptor
    • Hollenberg, S. M., and Evans, R. M. (1988) Multiple and cooperative trans-activation domains of the human glucocorticoid receptor. Cell 55(5), 899-906.
    • (1988) Cell , vol.55 , Issue.5 , pp. 899-906
    • Hollenberg, S.M.1    Evans, R.M.2
  • 26
    • 0030869037 scopus 로고    scopus 로고
    • Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70
    • Dittmar, K. D., Demady, D. R., Stancato, L. F., Krishna, P., and Pratt, W. B. (1997) Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70. J. Biol. Chem. 272(34), 21213-21220.
    • (1997) J. Biol. Chem. , vol.272 , Issue.34 , pp. 21213-21220
    • Dittmar, K.D.1    Demady, D.R.2    Stancato, L.F.3    Krishna, P.4    Pratt, W.B.5
  • 27
    • 0032571320 scopus 로고    scopus 로고
    • The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex
    • Dittmar, K. D., Banach, M., Galigniana, M. D., and Pratt, W. B. (1998) The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex. J. Biol. Chem. 273(13), 7358-7366.
    • (1998) J. Biol. Chem. , vol.273 , Issue.13 , pp. 7358-7366
    • Dittmar, K.D.1    Banach, M.2    Galigniana, M.D.3    Pratt, W.B.4
  • 29
    • 0029993518 scopus 로고    scopus 로고
    • The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function
    • Oakley, R. H., Sar, M., and Cidlowski, J. A. (1996) The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function. J. Biol. Chem. 271(16), 9550-9559.
    • (1996) J. Biol. Chem. , vol.271 , Issue.16 , pp. 9550-9559
    • Oakley, R.H.1    Sar, M.2    Cidlowski, J.A.3
  • 30
    • 0029088326 scopus 로고
    • Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation
    • Cole, T. J., et al. (1995) Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9(13), 1608-1621.
    • (1995) Genes Dev. , vol.9 , Issue.13 , pp. 1608-1621
    • Cole, T.J.1
  • 31
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan, N., DiDonato, J. A., Rosette, C., Helmberg, A., and Karin, M. (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270(5234), 286-290.
    • (1995) Science , vol.270 , Issue.5234 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 32
    • 0027402820 scopus 로고
    • Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene
    • Drouin, J., Sun, Y. L., Chamberland, M., Gauthier, Y., De Lean, A., Nemer, M., and Schmidt, T. J. (1993) Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12(1), 145-156.
    • (1993) EMBO J. , vol.12 , Issue.1 , pp. 145-156
    • Drouin, J.1    Sun, Y.L.2    Chamberland, M.3    Gauthier, Y.4    De Lean, A.5    Nemer, M.6    Schmidt, T.J.7
  • 33
    • 0024080921 scopus 로고
    • Hormone-mediated repression: A negative glucocorticoid response element from the bovine prolactin gene
    • Sakai, D. D., Helms, S., Carlstedt-Duke, J., Gustafsson, J. A., Rottman, F. M., and Yamamoto, K. R. (1988) Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes Dev. 2(9), 1144-1154.
    • (1988) Genes Dev. , vol.2 , Issue.9 , pp. 1144-1154
    • Sakai, D.D.1    Helms, S.2    Carlstedt-Duke, J.3    Gustafsson, J.A.4    Rottman, F.M.5    Yamamoto, K.R.6
  • 34
    • 0033485289 scopus 로고    scopus 로고
    • Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression
    • Webster, J. C., and Cidlowski, J. A. (1999) Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression. Trends Endocrinol. Metab. 10(10), 396-402.
    • (1999) Trends Endocrinol. Metab. , vol.10 , Issue.10 , pp. 396-402
    • Webster, J.C.1    Cidlowski, J.A.2
  • 36
    • 0025922666 scopus 로고
    • Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma
    • Almawi, W. Y., Lipman, M. L., Stevens, A. C., Zanker, B., Hadro, E. T., and Strom, T. B. (1991) Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma. J. Immunol. 146(10), 3523-3527.
    • (1991) J. Immunol. , vol.146 , Issue.10 , pp. 3523-3527
    • Almawi, W.Y.1    Lipman, M.L.2    Stevens, A.C.3    Zanker, B.4    Hadro, E.T.5    Strom, T.B.6
  • 39
    • 0033305547 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: Cellular and molecular biology
    • McKenna, N. J., Lanz, R. B., and O'Malley, B. W. (1999) Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 20(3), 321-344.
    • (1999) Endocr. Rev. , vol.20 , Issue.3 , pp. 321-344
    • McKenna, N.J.1    Lanz, R.B.2    O'Malley, B.W.3
  • 40
    • 0032934069 scopus 로고    scopus 로고
    • Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation
    • Wyszomierski, S. L., Yeh, J., and Rosen, J. M. (1999) Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. Mol. Endocrinol. 13(2), 330-343.
    • (1999) Mol. Endocrinol. , vol.13 , Issue.2 , pp. 330-343
    • Wyszomierski, S.L.1    Yeh, J.2    Rosen, J.M.3
  • 41
    • 0030998328 scopus 로고    scopus 로고
    • The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT
    • Jackson, T. A., Richer, J. K., Bain, D. L., Takimoto, G. S., Tung, L., and Horwitz, K. B. (1997) The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol. Endocrinol. 11(6), 693-705.
    • (1997) Mol. Endocrinol. , vol.11 , Issue.6 , pp. 693-705
    • Jackson, T.A.1    Richer, J.K.2    Bain, D.L.3    Takimoto, G.S.4    Tung, L.5    Horwitz, K.B.6
  • 42
    • 0032774277 scopus 로고    scopus 로고
    • Sex hormones and glucocorticoids: Interactions with the immune system
    • discussion 117-118
    • Da Silva, J. A. (1999) Sex hormones and glucocorticoids: interactions with the immune system. Ann. N. Y. Acad. Sci. 876, 102-117; discussion 117-118.
    • (1999) Ann. N. Y. Acad. Sci. , vol.876 , pp. 102-117
    • Da Silva, J.A.1
  • 43
    • 0036528901 scopus 로고    scopus 로고
    • Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: Evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids
    • Meduri, G. U., Tolley, E. A., Chrousos, G. P., and Stentz, F. (2002) Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am. J. Respir. Crit. Care Med. 165(7), 983-991.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , Issue.7 , pp. 983-991
    • Meduri, G.U.1    Tolley, E.A.2    Chrousos, G.P.3    Stentz, F.4
  • 44
    • 0032230316 scopus 로고    scopus 로고
    • A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids
    • Wissink, S., van Heerde, E. C., vand der Burg, B., and van der Saag, P. T. (1998) A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids. Mol. Endocrinol. 12(3), 355-363.
    • (1998) Mol. Endocrinol. , vol.12 , Issue.3 , pp. 355-363
    • Wissink, S.1    Van Heerde, E.C.2    Vand Der Burg, B.3    Van Der Saag, P.T.4
  • 45
    • 0031569536 scopus 로고    scopus 로고
    • Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun
    • Brostjan, C., Anrather, J., Csizmadia, V., Natarajan, G., and Winkler, H. (1997) Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun. J. Immunol. 158(8), 3836-3844.
    • (1997) J. Immunol. , vol.158 , Issue.8 , pp. 3836-3844
    • Brostjan, C.1    Anrather, J.2    Csizmadia, V.3    Natarajan, G.4    Winkler, H.5
  • 46
    • 0027934108 scopus 로고
    • A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1
    • Heck, S., Kullmann, M., Gast, A., Ponta, H., Rahmsdorf, H. J., Herrlich, P., and Cato, A. C. (1994) A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J. 13(17), 4087-4095.
    • (1994) EMBO J. , vol.13 , Issue.17 , pp. 4087-4095
    • Heck, S.1    Kullmann, M.2    Gast, A.3    Ponta, H.4    Rahmsdorf, H.J.5    Herrlich, P.6    Cato, A.C.7
  • 47
    • 0031916865 scopus 로고    scopus 로고
    • Cross-talk between nuclear factor-kappa B and the steroid hormone receptors: Mechanisms of mutual antagonism
    • McKay, L. I., and Cidlowski, J. A. (1998) Cross-talk between nuclear factor-kappa B and the steroid hormone receptors: mechanisms of mutual antagonism. Mol. Endocrinol. 12(1), 45-56.
    • (1998) Mol. Endocrinol. , vol.12 , Issue.1 , pp. 45-56
    • McKay, L.I.1    Cidlowski, J.A.2
  • 48
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheimnan, R. I., Cogswell, P. C., Lofquist, A. K., and Baldwin A. S. Jr. (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270(5234), 283-286.
    • (1995) Science , vol.270 , Issue.5234 , pp. 283-286
    • Scheimnan, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 49
    • 0033304494 scopus 로고    scopus 로고
    • Molecular control of immune/inflammatory responses: Interactions between nuclear factor-kappa B and steroid receptor-signaling pathways
    • McKay, L. I., and Cidlowski, J. A. (1999) Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways. Endocr. Rev. 20(4), 435-459.
    • (1999) Endocr. Rev. , vol.20 , Issue.4 , pp. 435-459
    • McKay, L.I.1    Cidlowski, J.A.2
  • 50
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
    • Nissen, R. M., and Yamamoto, K. R. (2000) The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 14(18), 2314-2329.
    • (2000) Genes Dev. , vol.14 , Issue.18 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 51
    • 0030480969 scopus 로고    scopus 로고
    • The CBP co-activator is a histone acetyltransferase
    • Bannister, A. J., and Kouzarides, T. (1996) The CBP co-activator is a histone acetyltransferase. Nature 384(6610), 641-643.
    • (1996) Nature , vol.384 , Issue.6610 , pp. 641-643
    • Bannister, A.J.1    Kouzarides, T.2
  • 52
    • 0033515428 scopus 로고    scopus 로고
    • Increasing the complexity of coactivation in nuclear receptor signaling
    • Freedman, L. P. (1999) Increasing the complexity of coactivation in nuclear receptor signaling. Cell 97(1), 5-8.
    • (1999) Cell , vol.97 , Issue.1 , pp. 5-8
    • Freedman, L.P.1
  • 53
    • 0034636021 scopus 로고    scopus 로고
    • Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
    • De Bosscher, K., Vanden Berghe, W., Vermeulen, L., Plaisance, S., Boone, E., and Haegeman, G. (2000) Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc. Natl. Acad. Sci. USA 97(8), 3919-3924.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.8 , pp. 3919-3924
    • De Bosscher, K.1    Vanden Berghe, W.2    Vermeulen, L.3    Plaisance, S.4    Boone, E.5    Haegeman, G.6
  • 54
    • 0034464826 scopus 로고    scopus 로고
    • CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism
    • McKay, L. I., and Cidlowski, J. A. (2000) CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism. Mol. Endocrinol. 14(8), 1222-1234.
    • (2000) Mol. Endocrinol. , vol.14 , Issue.8 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 55
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stocklin, E., Wissler, M., Gouilleux, F., and Groner, B. (1996) Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383(6602), 726-728.
    • (1996) Nature , vol.383 , Issue.6602 , pp. 726-728
    • Stocklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 57
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L., and Karin, M. (2001) Mammalian MAP kinase signalling cascades. Nature 410(6824), 37-40.
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 58
    • 0036841288 scopus 로고    scopus 로고
    • Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
    • Lasa, M., Abraham, S. M., Boucheron, C., Saklatvala, J., and Clark, A. R. (2002) Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol. Cell. Biol. 22(22), 7802-7811.
    • (2002) Mol. Cell. Biol. , vol.22 , Issue.22 , pp. 7802-7811
    • Lasa, M.1    Abraham, S.M.2    Boucheron, C.3    Saklatvala, J.4    Clark, A.R.5
  • 59
    • 0035810930 scopus 로고    scopus 로고
    • Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: A mechanism for the generation of glucocorticoid resistance
    • Webster, J. C., Oakley, R. H., Jewell, C. M., and Cidlowski, J. A. (2001) Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance. Proc. Natl. Acad. Sci. USA 98(12), 6865-6870.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.12 , pp. 6865-6870
    • Webster, J.C.1    Oakley, R.H.2    Jewell, C.M.3    Cidlowski, J.A.4


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