메뉴 건너뛰기




Volumn 17, Issue 6, 2015, Pages 636-644

Abnormal gene expression of proinflammatory cytokines and their receptors in the lymphocytes of patients with bipolar disorder

Author keywords

mRNA; Biomarkers; Bipolar illness; Cytokine receptors; Gene expression; Interleukin 1 receptors; Interleukin 6 receptors; Lymphocytes; Proinflammatory cytokines; Tumor necrosis factor receptors

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEMBRANE RECEPTOR; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 84941024830     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/bdi.12320     Document Type: Article
Times cited : (28)

References (50)
  • 1
    • 0033282369 scopus 로고    scopus 로고
    • Mechanisms of the behavioral effects of cytokines
    • Dantzer R, Wollman EE, Yirmiya R eds. New York, NY: Kluwer Academic/Plenum Publishers
    • Dantzer R, Aubert A, Bluthe R-M et al. Mechanisms of the behavioral effects of cytokines. In: Dantzer R, Wollman EE, Yirmiya R eds. Cytokines, Stress and Depression. New York, NY: Kluwer Academic/Plenum Publishers, 1999: 83-105.
    • (1999) Cytokines, Stress and Depression , pp. 83-105
    • Dantzer, R.1    Aubert, A.2    Bluthe, R.-M.3
  • 2
    • 0035038172 scopus 로고    scopus 로고
    • Cytokine-induced sickness behavior: mechanisms and implications
    • Dantzer R. Cytokine-induced sickness behavior: mechanisms and implications. Ann N Y Acad Sci 2001; 933: 222-234.
    • (2001) Ann N Y Acad Sci , vol.933 , pp. 222-234
    • Dantzer, R.1
  • 3
    • 0036199336 scopus 로고    scopus 로고
    • Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions
    • Capuron L, Gumnick JF, Musselman DL et al. Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. Neuropsychopharmacology 2002; 26: 643-652.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 643-652
    • Capuron, L.1    Gumnick, J.F.2    Musselman, D.L.3
  • 4
    • 4243187646 scopus 로고    scopus 로고
    • Neurotrophic signaling in mood disorders
    • Finkel T, Gutkind JS eds. Hoboken, NJ: John Wiley & Sons Inc
    • Du J, Gould TD, Manji HK. Neurotrophic signaling in mood disorders. In: Finkel T, Gutkind JS eds. Signal Transduction and Human Disease. Hoboken, NJ: John Wiley & Sons Inc, 2003: 411-447.
    • (2003) Signal Transduction and Human Disease , pp. 411-447
    • Du, J.1    Gould, T.D.2    Manji, H.K.3
  • 5
    • 0034661708 scopus 로고    scopus 로고
    • Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes
    • Greenberg DB, Jonasch E, Gadd MA et al. Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes. Cancer 2000; 89: 356-362.
    • (2000) Cancer , vol.89 , pp. 356-362
    • Greenberg, D.B.1    Jonasch, E.2    Gadd, M.A.3
  • 6
    • 84880133128 scopus 로고    scopus 로고
    • Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis
    • Munkholm K, Brauner JV, Kessing LV, Vinberg M. Cytokines in bipolar disorder vs. healthy control subjects: a systematic review and meta-analysis. J Psychiatr Res 2013; 47: 1119-1133.
    • (2013) J Psychiatr Res , vol.47 , pp. 1119-1133
    • Munkholm, K.1    Brauner, J.V.2    Kessing, L.V.3    Vinberg, M.4
  • 7
    • 84870298815 scopus 로고    scopus 로고
    • Cytokines in bipolar disorder: a systematic review and meta-analysis
    • Munkholm K, Vinberg M, Vedel Kessing L. Cytokines in bipolar disorder: a systematic review and meta-analysis. J Affect Disord 2013; 144: 16-27.
    • (2013) J Affect Disord , vol.144 , pp. 16-27
    • Munkholm, K.1    Vinberg, M.2    Vedel Kessing, L.3
  • 8
    • 84879317123 scopus 로고    scopus 로고
    • Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies
    • Modabbernia A, Taslimi S, Brietzke E, Ashrafi M. Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies. Biol Psychiatry 2013; 74: 15-25.
    • (2013) Biol Psychiatry , vol.74 , pp. 15-25
    • Modabbernia, A.1    Taslimi, S.2    Brietzke, E.3    Ashrafi, M.4
  • 9
    • 84881416732 scopus 로고    scopus 로고
    • Immunity, inflammation, and bipolar disorder: diagnostic and therapeutic implications
    • Hamdani N, Doukhan R, Kurtlucan O, Tamouza R, Leboyer M. Immunity, inflammation, and bipolar disorder: diagnostic and therapeutic implications. Curr Psychiatry Rep 2013; 15: 387.
    • (2013) Curr Psychiatry Rep , vol.15 , pp. 387
    • Hamdani, N.1    Doukhan, R.2    Kurtlucan, O.3    Tamouza, R.4    Leboyer, M.5
  • 10
    • 79952243496 scopus 로고    scopus 로고
    • Increased plasma levels of soluble TNF receptor I in patients with bipolar disorder
    • Barbosa IG, Huguet RB, Mendonca VA et al. Increased plasma levels of soluble TNF receptor I in patients with bipolar disorder. Eur Arch Psychiatry Clin Neurosci 2011; 261: 139-143.
    • (2011) Eur Arch Psychiatry Clin Neurosci , vol.261 , pp. 139-143
    • Barbosa, I.G.1    Huguet, R.B.2    Mendonca, V.A.3
  • 11
    • 0029146932 scopus 로고
    • Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
    • Maes M, Meltzer HY, Bosmans E et al. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J Affect Disord 1995; 34: 301-309.
    • (1995) J Affect Disord , vol.34 , pp. 301-309
    • Maes, M.1    Meltzer, H.Y.2    Bosmans, E.3
  • 12
    • 31844457040 scopus 로고    scopus 로고
    • Cytokine profiles in bipolar affective disorder: focus on acutely ill patients
    • O'Brien SM, Scully P, Scott LV, Dinan TG. Cytokine profiles in bipolar affective disorder: focus on acutely ill patients. J Affect Disord 2006; 90: 263-267.
    • (2006) J Affect Disord , vol.90 , pp. 263-267
    • O'Brien, S.M.1    Scully, P.2    Scott, L.V.3    Dinan, T.G.4
  • 13
    • 72649084925 scopus 로고    scopus 로고
    • Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder
    • Brietzke E, Kauer-Sant'Anna M, Teixeira AL, Kapczinski F. Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder. Brain Behav Immun 2009; 23: 1079-1082.
    • (2009) Brain Behav Immun , vol.23 , pp. 1079-1082
    • Brietzke, E.1    Kauer-Sant'Anna, M.2    Teixeira, A.L.3    Kapczinski, F.4
  • 14
    • 79954598830 scopus 로고    scopus 로고
    • Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
    • Maes M. Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 664-675.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 664-675
    • Maes, M.1
  • 15
    • 42049092538 scopus 로고    scopus 로고
    • A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
    • Padmos RC, Hillegers MH, Knijff EM et al. A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry 2008; 65: 395-407.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 395-407
    • Padmos, R.C.1    Hillegers, M.H.2    Knijff, E.M.3
  • 16
    • 0028246158 scopus 로고
    • The Clinician-Administered Rating Scale for Mania (CARS-M): development, reliability, and validity
    • Altman EG, Hedeker DR, Janicak PG, Peterson JL, Davis JM. The Clinician-Administered Rating Scale for Mania (CARS-M): development, reliability, and validity. Biol Psychiatry 1994; 36: 124-134.
    • (1994) Biol Psychiatry , vol.36 , pp. 124-134
    • Altman, E.G.1    Hedeker, D.R.2    Janicak, P.G.3    Peterson, J.L.4    Davis, J.M.5
  • 17
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 18
    • 0026516744 scopus 로고
    • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
    • Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med 1992; 175: 323-329.
    • (1992) J Exp Med , vol.175 , pp. 323-329
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 19
    • 0026058710 scopus 로고
    • Soluble cytokine receptors: their role in immunoregulation
    • Fernandez-Botran R. Soluble cytokine receptors: their role in immunoregulation. FASEB J 1991; 5: 2567-2574.
    • (1991) FASEB J , vol.5 , pp. 2567-2574
    • Fernandez-Botran, R.1
  • 20
    • 0030322237 scopus 로고    scopus 로고
    • Cytokines as mediators in the pathogenesis of septic shock
    • Dinarello CA. Cytokines as mediators in the pathogenesis of septic shock. Curr Top Microbiol Immunol 1996; 216: 133-165.
    • (1996) Curr Top Microbiol Immunol , vol.216 , pp. 133-165
    • Dinarello, C.A.1
  • 21
    • 0025899561 scopus 로고
    • A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types
    • McMahan CJ, Slack JL, Mosley B et al. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J 1991; 10: 2821-2832.
    • (1991) EMBO J , vol.10 , pp. 2821-2832
    • McMahan, C.J.1    Slack, J.L.2    Mosley, B.3
  • 22
    • 0024408830 scopus 로고
    • Cloning the interleukin 1 receptor from human T cells
    • Sims JE, Acres RB, Grubin CE et al. Cloning the interleukin 1 receptor from human T cells. Proc Natl Acad Sci USA 1989; 86: 8946-8950.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8946-8950
    • Sims, J.E.1    Acres, R.B.2    Grubin, C.E.3
  • 23
    • 0028143674 scopus 로고
    • The IL-1 receptor signaling pathway
    • Kuno K, Matsushima K. The IL-1 receptor signaling pathway. J Leukoc Biol 1994; 56: 542-547.
    • (1994) J Leukoc Biol , vol.56 , pp. 542-547
    • Kuno, K.1    Matsushima, K.2
  • 24
    • 0025713953 scopus 로고
    • Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor
    • Hannum CH, Wilcox CJ, Arend WP et al. Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor. Nature 1990; 343: 336-340.
    • (1990) Nature , vol.343 , pp. 336-340
    • Hannum, C.H.1    Wilcox, C.J.2    Arend, W.P.3
  • 25
    • 0025787689 scopus 로고
    • Interleukin 1 receptor antagonist. A new member of the interleukin 1 family
    • Arend WP. Interleukin 1 receptor antagonist. A new member of the interleukin 1 family. J Clin Invest 1991; 88: 1445-1451.
    • (1991) J Clin Invest , vol.88 , pp. 1445-1451
    • Arend, W.P.1
  • 26
    • 2442605821 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane bound and soluble receptors
    • Rose-John S. Interleukin-6 biology is coordinated by membrane bound and soluble receptors. Acta Biochim Pol 2003; 50: 603-611.
    • (2003) Acta Biochim Pol , vol.50 , pp. 603-611
    • Rose-John, S.1
  • 27
    • 33748848714 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
    • Rose-John S, Scheller J, Elson G, Jones SA. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol 2006; 80: 227-236.
    • (2006) J Leukoc Biol , vol.80 , pp. 227-236
    • Rose-John, S.1    Scheller, J.2    Elson, G.3    Jones, S.A.4
  • 28
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: a beautiful pathway
    • Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 2002; 296: 1634-1635.
    • (2002) Science , vol.296 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 29
    • 26044438460 scopus 로고    scopus 로고
    • Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system
    • Pickering M, Cumiskey D, O'Connor JJ. Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system. Exp Physiol 2005; 90: 663-670.
    • (2005) Exp Physiol , vol.90 , pp. 663-670
    • Pickering, M.1    Cumiskey, D.2    O'Connor, J.J.3
  • 30
    • 0025014985 scopus 로고
    • Tumour necrosis factor signal transduction
    • Kronke M, Schutze S, Scheurich P et al. Tumour necrosis factor signal transduction. Cell Signal 1990; 2: 1-8.
    • (1990) Cell Signal , vol.2 , pp. 1-8
    • Kronke, M.1    Schutze, S.2    Scheurich, P.3
  • 31
    • 0026673687 scopus 로고
    • Tumor necrosis factor receptors - structure and function
    • Rothe J, Gehr G, Loetscher H, Lesslauer W. Tumor necrosis factor receptors - structure and function. Immunol Res 1992; 11: 81-90.
    • (1992) Immunol Res , vol.11 , pp. 81-90
    • Rothe, J.1    Gehr, G.2    Loetscher, H.3    Lesslauer, W.4
  • 32
    • 36549059241 scopus 로고    scopus 로고
    • TNF signaling: early events and phosphorylation
    • Ihnatko R, Kubes M. TNF signaling: early events and phosphorylation. Gen Physiol Biophys 2007; 26: 159-167.
    • (2007) Gen Physiol Biophys , vol.26 , pp. 159-167
    • Ihnatko, R.1    Kubes, M.2
  • 33
    • 84887013838 scopus 로고    scopus 로고
    • Soluble TNF and IL-6 receptors: indicators of vascular health in women without cardiovascular disease
    • Cortez-Cooper M, Meaders E, Stallings J et al. Soluble TNF and IL-6 receptors: indicators of vascular health in women without cardiovascular disease. Vasc Med 2013; 18: 282-289.
    • (2013) Vasc Med , vol.18 , pp. 282-289
    • Cortez-Cooper, M.1    Meaders, E.2    Stallings, J.3
  • 35
    • 34548412812 scopus 로고    scopus 로고
    • Immune variations in bipolar disorder: phasic differences
    • Ortiz-Dominguez A, Hernandez ME, Berlanga C et al. Immune variations in bipolar disorder: phasic differences. Bipolar Disord 2007; 9: 596-602.
    • (2007) Bipolar Disord , vol.9 , pp. 596-602
    • Ortiz-Dominguez, A.1    Hernandez, M.E.2    Berlanga, C.3
  • 36
    • 80355146928 scopus 로고    scopus 로고
    • Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
    • Hope S, Dieset I, Agartz I et al. Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia. J Psychiatr Res 2011; 45: 1608-1616.
    • (2011) J Psychiatr Res , vol.45 , pp. 1608-1616
    • Hope, S.1    Dieset, I.2    Agartz, I.3
  • 37
    • 70350539633 scopus 로고    scopus 로고
    • Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    • Hope S, Melle I, Aukrust P et al. Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor. Bipolar Disord 2009; 11: 726-734.
    • (2009) Bipolar Disord , vol.11 , pp. 726-734
    • Hope, S.1    Melle, I.2    Aukrust, P.3
  • 38
    • 84875267862 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
    • Hope S, Ueland T, Steen NE et al. Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder. Schizophr Res 2013; 145: 36-42.
    • (2013) Schizophr Res , vol.145 , pp. 36-42
    • Hope, S.1    Ueland, T.2    Steen, N.E.3
  • 39
    • 84857050654 scopus 로고    scopus 로고
    • Inflammatory markers and their relationships with leptin and insulin from acute mania to full remission in bipolar disorder
    • Tsai SY, Chung KH, Wu JY, Kuo CJ, Lee HC, Huang SH. Inflammatory markers and their relationships with leptin and insulin from acute mania to full remission in bipolar disorder. J Affect Disord 2012; 136: 110-116.
    • (2012) J Affect Disord , vol.136 , pp. 110-116
    • Tsai, S.Y.1    Chung, K.H.2    Wu, J.Y.3    Kuo, C.J.4    Lee, H.C.5    Huang, S.H.6
  • 40
    • 78650677712 scopus 로고    scopus 로고
    • Peripheral biomarkers and illness activity in bipolar disorder
    • Kapczinski F, Dal-Pizzol F, Teixeira AL et al. Peripheral biomarkers and illness activity in bipolar disorder. J Psychiatr Res 2011; 45: 156-161.
    • (2011) J Psychiatr Res , vol.45 , pp. 156-161
    • Kapczinski, F.1    Dal-Pizzol, F.2    Teixeira, A.L.3
  • 42
    • 4444256765 scopus 로고    scopus 로고
    • Cytokines: abnormalities in major depression and implications for pharmacological treatment
    • O'Brien SM, Scott LV, Dinan TG. Cytokines: abnormalities in major depression and implications for pharmacological treatment. Hum Psychopharmacol 2004; 19: 397-403.
    • (2004) Hum Psychopharmacol , vol.19 , pp. 397-403
    • O'Brien, S.M.1    Scott, L.V.2    Dinan, T.G.3
  • 44
    • 0027970546 scopus 로고
    • Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain
    • Schobitz B, De Kloet ER, Holsboer F. Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Progr Neurobiol 1994; 44: 397-432.
    • (1994) Progr Neurobiol , vol.44 , pp. 397-432
    • Schobitz, B.1    De Kloet, E.R.2    Holsboer, F.3
  • 45
    • 0028800715 scopus 로고
    • Cytokines and the nervous system. I: expression and recognition
    • Hopkins SJ, Rothwell NJ. Cytokines and the nervous system. I: expression and recognition. Trends Neurosci 1995; 18: 83-88.
    • (1995) Trends Neurosci , vol.18 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 46
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008; 9: 46-56.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 49
    • 77950022786 scopus 로고    scopus 로고
    • Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
    • Rao JS, Harry GJ, Rapoport SI, Kim HW. Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol Psychiatry 2010; 15: 384-392.
    • (2010) Mol Psychiatry , vol.15 , pp. 384-392
    • Rao, J.S.1    Harry, G.J.2    Rapoport, S.I.3    Kim, H.W.4
  • 50
    • 81855198982 scopus 로고    scopus 로고
    • Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims
    • Pandey GN, Rizavi HS, Ren X et al. Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims. J Psychiatr Res 2012; 46: 57-63.
    • (2012) J Psychiatr Res , vol.46 , pp. 57-63
    • Pandey, G.N.1    Rizavi, H.S.2    Ren, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.