-
1
-
-
57349165831
-
Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production
-
COI: 1:CAS:528:DC%2BD1MXmt1ymtA%3D%3D, PID: 19035506
-
Abdollahi-Roodsaz S, Joosten LA, Helsen MM, Walgreen B, Van Lent PL, Van Den Bersselaar LA, Koenders MI, Van Den Berg WB (2008) Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production. Arthritis Rheum 58:3753–3764
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3753-3764
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Helsen, M.M.3
Walgreen, B.4
Van Lent, P.L.5
Van Den Bersselaar, L.A.6
Koenders, M.I.7
Van Den Berg, W.B.8
-
2
-
-
0037672694
-
Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling
-
COI: 1:CAS:528:DC%2BD3sXls1Gmtbo%3D, PID: 12792852
-
Akira S, Hoshino K (2003) Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling. J Infect Dis 187(Suppl 2):S356–S363
-
(2003)
J Infect Dis
, vol.187
, pp. S356-S363
-
-
Akira, S.1
Hoshino, K.2
-
3
-
-
84861990802
-
Investigation of the role of endosomal toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance
-
COI: 1:CAS:528:DC%2BC38XhtVaku77I, PID: 22691272
-
Alzabin S, Kong P, Medghalchi M, Palfreeman A, Williams R, Sacre S (2012) Investigation of the role of endosomal toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance. Arthritis Res Ther 14:R142
-
(2012)
Arthritis Res Ther
, vol.14
, pp. R142
-
-
Alzabin, S.1
Kong, P.2
Medghalchi, M.3
Palfreeman, A.4
Williams, R.5
Sacre, S.6
-
4
-
-
84875932685
-
Negative regulatory approaches to the attenuation of toll-like receptor signaling
-
PID: 23429360
-
Anwar MA, Basith S, Choi S (2013) Negative regulatory approaches to the attenuation of toll-like receptor signaling. Exp Mol Med 45:e11
-
(2013)
Exp Mol Med
, vol.45
-
-
Anwar, M.A.1
Basith, S.2
Choi, S.3
-
5
-
-
47149084387
-
Bridging innate immunity and myocardial ischemia/reperfusion injury: the search for therapeutic targets
-
COI: 1:CAS:528:DC%2BD1cXns1yntbo%3D, PID: 18473868
-
Arslan F, De Kleijn DP, Timmers L, Doevendans PA, Pasterkamp G (2008) Bridging innate immunity and myocardial ischemia/reperfusion injury: the search for therapeutic targets. Curr Pharm Des 14:1205–1216
-
(2008)
Curr Pharm Des
, vol.14
, pp. 1205-1216
-
-
Arslan, F.1
De Kleijn, D.P.2
Timmers, L.3
Doevendans, P.A.4
Pasterkamp, G.5
-
6
-
-
84860789456
-
Treatment with OPN-305, a humanized anti-toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs
-
COI: 1:CAS:528:DC%2BC38Xos1Wjs7w%3D, PID: 22354933
-
Arslan F, Houtgraaf JH, Keogh B, Kazemi K, De Jong R, Mccormack WJ, O’neill LA, Mcguirk P, Timmers L, Smeets MB, Akeroyd L, Reilly M, Pasterkamp G, De Kleijn DP (2012) Treatment with OPN-305, a humanized anti-toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs. Circ Cardiovasc Interv 5:279–287
-
(2012)
Circ Cardiovasc Interv
, vol.5
, pp. 279-287
-
-
Arslan, F.1
Houtgraaf, J.H.2
Keogh, B.3
Kazemi, K.4
De Jong, R.5
Mccormack, W.J.6
O’neill, L.A.7
Mcguirk, P.8
Timmers, L.9
Smeets, M.B.10
Akeroyd, L.11
Reilly, M.12
Pasterkamp, G.13
De Kleijn, D.P.14
-
7
-
-
42649118787
-
TLR2 and age-related diseases: potential effects of Arg753Gln and Arg677Trp polymorphisms in acute myocardial infarction
-
COI: 1:CAS:528:DC%2BD1cXlt1ans78%3D, PID: 18442320
-
Balistreri CR, Candore G, Mirabile M, Lio D, Caimi G, Incalcaterra E, Caruso M, Hoffmann E, Caruso C (2008) TLR2 and age-related diseases: potential effects of Arg753Gln and Arg677Trp polymorphisms in acute myocardial infarction. Rejuvenation Res 11:293–296
-
(2008)
Rejuvenation Res
, vol.11
, pp. 293-296
-
-
Balistreri, C.R.1
Candore, G.2
Mirabile, M.3
Lio, D.4
Caimi, G.5
Incalcaterra, E.6
Caruso, M.7
Hoffmann, E.8
Caruso, C.9
-
8
-
-
84884215297
-
Sterile-α- and armadillo motif-containing protein inhibits the TRIF-dependent downregulation of signal regulatory protein α to interfere with intracellular bacterial elimination in Burkholderia pseudomallei-infected mouse macrophages
-
COI: 1:CAS:528:DC%2BC3sXhtlCmur7F, PID: 23836818
-
Baral P, Utaisincharoen P (2013) Sterile-α- and armadillo motif-containing protein inhibits the TRIF-dependent downregulation of signal regulatory protein α to interfere with intracellular bacterial elimination in Burkholderia pseudomallei-infected mouse macrophages. Infect Immun 81:3463–3471
-
(2013)
Infect Immun
, vol.81
, pp. 3463-3471
-
-
Baral, P.1
Utaisincharoen, P.2
-
9
-
-
79956188587
-
Toll-like receptor modulators: a patent review (2006–2010)
-
COI: 1:CAS:528:DC%2BC3MXmt1ymurs%3D, PID: 21406035
-
Basith S, Manavalan B, Lee G, Kim SG, Choi S (2011) Toll-like receptor modulators: a patent review (2006–2010). Expert Opin Ther Pat 21:927–944
-
(2011)
Expert Opin Ther Pat
, vol.21
, pp. 927-944
-
-
Basith, S.1
Manavalan, B.2
Lee, G.3
Kim, S.G.4
Choi, S.5
-
10
-
-
80053511704
-
Induction of experimental arthritis by borrelial lipoprotein and CpG motifs: are toll-like receptors 2, 4, 9 or CD-14 involved?
-
COI: 1:CAS:528:DC%2BC3MXhtFWiu7zE, PID: 21804904
-
Batsford S, Dunn J, Mihatsch M (2011) Induction of experimental arthritis by borrelial lipoprotein and CpG motifs: are toll-like receptors 2, 4, 9 or CD-14 involved? Open Rheumatol J 5:18–23
-
(2011)
Open Rheumatol J
, vol.5
, pp. 18-23
-
-
Batsford, S.1
Dunn, J.2
Mihatsch, M.3
-
11
-
-
84858197367
-
Dual role of toll-like receptors in asthma and chronic obstructive pulmonary disease
-
COI: 1:CAS:528:DC%2BC38XmslKktr0%3D, PID: 22407613
-
Bezemer GF, Sagar S, Van Bergenhenegouwen J, Georgiou NA, Garssen J, Kraneveld AD, Folkerts G (2012) Dual role of toll-like receptors in asthma and chronic obstructive pulmonary disease. Pharmacol Rev 64:337–358
-
(2012)
Pharmacol Rev
, vol.64
, pp. 337-358
-
-
Bezemer, G.F.1
Sagar, S.2
Van Bergenhenegouwen, J.3
Georgiou, N.A.4
Garssen, J.5
Kraneveld, A.D.6
Folkerts, G.7
-
12
-
-
84906071028
-
Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses
-
PID: 24958710
-
Bhinder G, Stahl M, Sham HP, Crowley SM, Morampudi V, Dalwadi U, Ma C, Jacobson K, Vallance BA (2014) Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses. Infect Immun 82:3753–3763
-
(2014)
Infect Immun
, vol.82
, pp. 3753-3763
-
-
Bhinder, G.1
Stahl, M.2
Sham, H.P.3
Crowley, S.M.4
Morampudi, V.5
Dalwadi, U.6
Ma, C.7
Jacobson, K.8
Vallance, B.A.9
-
13
-
-
33845951211
-
DAMPs, PAMPs and alarmins: all we need to know about danger
-
COI: 1:CAS:528:DC%2BD2sXktVaisg%3D%3D, PID: 17032697
-
Bianchi ME (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81:1–5
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
14
-
-
79959726848
-
Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the atherosclerosis risk in communities MRI study
-
COI: 1:CAS:528:DC%2BC3MXlvFOit7k%3D, PID: 21298446
-
Bielinski SJ, Hall JL, Pankow JS, Boerwinkle E, Matijevic-Aleksic N, He M, Chambless L, Folsom AR (2011) Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the atherosclerosis risk in communities MRI study. Hum Genet 129:655–662
-
(2011)
Hum Genet
, vol.129
, pp. 655-662
-
-
Bielinski, S.J.1
Hall, J.L.2
Pankow, J.S.3
Boerwinkle, E.4
Matijevic-Aleksic, N.5
He, M.6
Chambless, L.7
Folsom, A.R.8
-
15
-
-
77949940198
-
Intracellular toll-like receptors
-
COI: 1:CAS:528:DC%2BC3cXlsVSntr4%3D, PID: 20346772
-
Blasius AL, Beutler B (2010) Intracellular toll-like receptors. Immunity 32:305–315
-
(2010)
Immunity
, vol.32
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
16
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses
-
COI: 1:CAS:528:DC%2BD2cXnvFCgsro%3D, PID: 15334086
-
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, Hurley P, Chien M, Chai S, Hitotsumatsu O, Mcnally E, Pickart C, Ma A (2004) The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses. Nat Immunol 5:1052–1060
-
(2004)
Nat Immunol
, vol.5
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
Ahmad, R.C.4
Wheeler, M.T.5
Tsui, C.6
Hurley, P.7
Chien, M.8
Chai, S.9
Hitotsumatsu, O.10
Mcnally, E.11
Pickart, C.12
Ma, A.13
-
17
-
-
2942721674
-
ST2 is an inhibitor of interleukin 1 receptor and toll-like receptor 4 signaling and maintains endotoxin tolerance
-
COI: 1:CAS:528:DC%2BD2cXisF2ktb8%3D, PID: 15004556
-
Brint EK, Xu D, Liu H, Dunne A, Mckenzie AN, O’neill LA, Liew FY (2004) ST2 is an inhibitor of interleukin 1 receptor and toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol 5:373–379
-
(2004)
Nat Immunol
, vol.5
, pp. 373-379
-
-
Brint, E.K.1
Xu, D.2
Liu, H.3
Dunne, A.4
Mckenzie, A.N.5
O’neill, L.A.6
Liew, F.Y.7
-
18
-
-
79954577277
-
TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk
-
COI: 1:CAS:528:DC%2BC3MXltVKhsb4%3D, PID: 20940366
-
Brown J, Wang H, Hajishengallis GN, Martin M (2011) TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J Dent Res 90:417–427
-
(2011)
J Dent Res
, vol.90
, pp. 417-427
-
-
Brown, J.1
Wang, H.2
Hajishengallis, G.N.3
Martin, M.4
-
19
-
-
84949116865
-
Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment
-
PID: 25538618
-
Celhar T, Fairhurst AM (2014) Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment. Front Pharmacol 5:265
-
(2014)
Front Pharmacol
, vol.5
, pp. 265
-
-
Celhar, T.1
Fairhurst, A.M.2
-
20
-
-
84957442991
-
Toll-like receptor pathways in autoimmune diseases
-
COI: 1:CAS:528:DC%2BC2MXjtlSqsrg%3D, PID: 25687121
-
Chen JQ, Szodoray P, Zeher M (2016) Toll-like receptor pathways in autoimmune diseases. Clin Rev Allergy Immunol 50:1–17
-
(2016)
Clin Rev Allergy Immunol
, vol.50
, pp. 1-17
-
-
Chen, J.Q.1
Szodoray, P.2
Zeher, M.3
-
21
-
-
84892687024
-
Modulation of CD14 and TLR4.MD-2 activities by a synthetic lipid A mimetic
-
COI: 1:CAS:528:DC%2BC3sXhvFWrtb%2FE, PID: 24339336
-
Cighetti R, Ciaramelli C, Sestito SE, Zanoni I, Kubik L, Arda-Freire A, Calabrese V, Granucci F, Jerala R, Martin-Santamaria S, Jimenez-Barbero J, Peri F (2014) Modulation of CD14 and TLR4.MD-2 activities by a synthetic lipid A mimetic. ChemBioChem 15:250–258
-
(2014)
ChemBioChem
, vol.15
, pp. 250-258
-
-
Cighetti, R.1
Ciaramelli, C.2
Sestito, S.E.3
Zanoni, I.4
Kubik, L.5
Arda-Freire, A.6
Calabrese, V.7
Granucci, F.8
Jerala, R.9
Martin-Santamaria, S.10
Jimenez-Barbero, J.11
Peri, F.12
-
22
-
-
84950109341
-
Endosomal toll-like receptors in clinically overt and silent autoimmunity
-
COI: 1:CAS:528:DC%2BC2MXitVeqtr3I, PID: 26683146
-
Clancy RM, Markham AJ, Buyon JP (2016) Endosomal toll-like receptors in clinically overt and silent autoimmunity. Immunol Rev 269:76–84
-
(2016)
Immunol Rev
, vol.269
, pp. 76-84
-
-
Clancy, R.M.1
Markham, A.J.2
Buyon, J.P.3
-
23
-
-
5444254408
-
Toll-like receptors in the pathogenesis of human disease
-
COI: 1:CAS:528:DC%2BD2cXnvFCgs74%3D, PID: 15454920
-
Cook DN, Pisetsky DS, Schwartz DA (2004) Toll-like receptors in the pathogenesis of human disease. Nat Immunol 5:975–979
-
(2004)
Nat Immunol
, vol.5
, pp. 975-979
-
-
Cook, D.N.1
Pisetsky, D.S.2
Schwartz, D.A.3
-
24
-
-
0037069791
-
Toll-like receptor 4 polymorphisms and atherogenesis
-
PID: 12477953
-
Cooke GS, Segal S, Hill AV, Tuberculosis G, Environment Study G, Oxford Pneumococcal Surveillance Study G (2002) Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 347:1978–1980
-
(2002)
N Engl J Med
, vol.347
, pp. 1978-1980
-
-
Cooke, G.S.1
Segal, S.2
Hill, A.V.3
Tuberculosis, G.4
Environment Study, G.5
Oxford Pneumococcal Surveillance Study, G.6
-
25
-
-
79959937269
-
Th17 cells: new players in asthma pathogenesis
-
COI: 1:CAS:528:DC%2BC3MXhtV2qsbzI, PID: 21375540
-
Cosmi L, Liotta F, Maggi E, Romagnani S, Annunziato F (2011) Th17 cells: new players in asthma pathogenesis. Allergy 66:989–998
-
(2011)
Allergy
, vol.66
, pp. 989-998
-
-
Cosmi, L.1
Liotta, F.2
Maggi, E.3
Romagnani, S.4
Annunziato, F.5
-
26
-
-
0037326549
-
Innate immune-related receptors in normal and psoriatic skin
-
COI: 1:CAS:528:DC%2BD3sXmsVCjs7g%3D, PID: 12562231
-
Curry JL, Qin JZ, Bonish B, Carrick R, Bacon P, Panella J, Robinson J, Nickoloff BJ (2003) Innate immune-related receptors in normal and psoriatic skin. Arch Pathol Lab Med 127:178–186
-
(2003)
Arch Pathol Lab Med
, vol.127
, pp. 178-186
-
-
Curry, J.L.1
Qin, J.Z.2
Bonish, B.3
Carrick, R.4
Bacon, P.5
Panella, J.6
Robinson, J.7
Nickoloff, B.J.8
-
27
-
-
84920747387
-
Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: an observational cohort study
-
COI: 1:CAS:528:DC%2BC2MXmsleitw%3D%3D, PID: 25573402
-
Davis ML, Levan TD, Yu F, Sayles H, Sokolove J, Robinson W, Michaud K, Thiele GM, Mikuls TR (2015) Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: an observational cohort study. Int Immunopharmacol 24:346–352
-
(2015)
Int Immunopharmacol
, vol.24
, pp. 346-352
-
-
Davis, M.L.1
Levan, T.D.2
Yu, F.3
Sayles, H.4
Sokolove, J.5
Robinson, W.6
Michaud, K.7
Thiele, G.M.8
Mikuls, T.R.9
-
28
-
-
84949627341
-
Toll-like receptors: activation, signalling and transcriptional modulation
-
PID: 25846205
-
De Nardo D (2015) Toll-like receptors: activation, signalling and transcriptional modulation. Cytokine 74:181–189
-
(2015)
Cytokine
, vol.74
, pp. 181-189
-
-
De Nardo, D.1
-
29
-
-
53349108327
-
Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis
-
COI: 1:CAS:528:DC%2BD1cXht12iurbI, PID: 18854239
-
Depaolo RW, Tang F, Kim I, Han M, Levin N, Ciletti N, Lin A, Anderson D, Schneewind O, Jabri B (2008) Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host Microbe 4:350–361
-
(2008)
Cell Host Microbe
, vol.4
, pp. 350-361
-
-
Depaolo, R.W.1
Tang, F.2
Kim, I.3
Han, M.4
Levin, N.5
Ciletti, N.6
Lin, A.7
Anderson, D.8
Schneewind, O.9
Jabri, B.10
-
30
-
-
84866480526
-
A specific role for TLR1 in protective T(H)17 immunity during mucosal infection
-
COI: 1:CAS:528:DC%2BC38XhtFOgurjO, PID: 22778390
-
Depaolo RW, Kamdar K, Khakpour S, Sugiura Y, Wang W, Jabri B (2012) A specific role for TLR1 in protective T(H)17 immunity during mucosal infection. J Exp Med 209:1437–1444
-
(2012)
J Exp Med
, vol.209
, pp. 1437-1444
-
-
Depaolo, R.W.1
Kamdar, K.2
Khakpour, S.3
Sugiura, Y.4
Wang, W.5
Jabri, B.6
-
31
-
-
84881486019
-
Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-beta includes upregulation of TLR7 in plasmacytoid dendritic cells
-
COI: 1:CAS:528:DC%2BC3sXhtlamsLfF, PID: 23950974
-
Derkow K, Bauer JM, Hecker M, Paap BK, Thamilarasan M, Koczan D, Schott E, Deuschle K, Bellmann-Strobl J, Paul F, Zettl UK, Ruprecht K, Lehnardt S (2013) Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-beta includes upregulation of TLR7 in plasmacytoid dendritic cells. PLoS One 8:e70626
-
(2013)
PLoS One
, vol.8
-
-
Derkow, K.1
Bauer, J.M.2
Hecker, M.3
Paap, B.K.4
Thamilarasan, M.5
Koczan, D.6
Schott, E.7
Deuschle, K.8
Bellmann-Strobl, J.9
Paul, F.10
Zettl, U.K.11
Ruprecht, K.12
Lehnardt, S.13
-
32
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
COI: 1:CAS:528:DC%2BD2cXhslCgsb4%3D, PID: 14976261
-
Diebold SS, Kaisho T, Hemmi H, Akira S, E Sousa CR (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529–1531
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
E Sousa, C.R.5
-
33
-
-
20644450101
-
Negative regulation of toll-like receptor 4 signaling by the toll-like receptor homolog RP105
-
COI: 1:CAS:528:DC%2BD2MXktlWitrg%3D, PID: 15852007
-
Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL (2005) Negative regulation of toll-like receptor 4 signaling by the toll-like receptor homolog RP105. Nat Immunol 6:571–578
-
(2005)
Nat Immunol
, vol.6
, pp. 571-578
-
-
Divanovic, S.1
Trompette, A.2
Atabani, S.F.3
Madan, R.4
Golenbock, D.T.5
Visintin, A.6
Finberg, R.W.7
Tarakhovsky, A.8
Vogel, S.N.9
Belkaid, Y.10
Kurt-Jones, E.A.11
Karp, C.L.12
-
34
-
-
84997242286
-
NI-0101, a therapeutic TLR 4 monoclonal antibody for rheumatoid arthritis
-
Elson G, Page T, Buatois V, Daubeuf B, Chatel L, Cons L, Lippens C, Salgado-Pires S, Ferlin W, Kosco-Vilbois M, Midwood K, Shang L (2011) NI-0101, a therapeutic TLR 4 monoclonal antibody for rheumatoid arthritis. Arthritis Rheum 63:977
-
(2011)
Arthritis Rheum
, vol.63
, pp. 977
-
-
Elson, G.1
Page, T.2
Buatois, V.3
Daubeuf, B.4
Chatel, L.5
Cons, L.6
Lippens, C.7
Salgado-Pires, S.8
Ferlin, W.9
Kosco-Vilbois, M.10
Midwood, K.11
Shang, L.12
-
35
-
-
84904048838
-
VGX-1027 modulates genes involved in lipopolysaccharide-induced toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus
-
COI: 1:CAS:528:DC%2BC2cXhtFeitrnK, PID: 24527796
-
Fagone P, Muthumani K, Mangano K, Magro G, Meroni PL, Kim JJ, Sardesai NY, Weiner DB, Nicoletti F (2014) VGX-1027 modulates genes involved in lipopolysaccharide-induced toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus. Immunology 142:594–602
-
(2014)
Immunology
, vol.142
, pp. 594-602
-
-
Fagone, P.1
Muthumani, K.2
Mangano, K.3
Magro, G.4
Meroni, P.L.5
Kim, J.J.6
Sardesai, N.Y.7
Weiner, D.B.8
Nicoletti, F.9
-
36
-
-
42049105363
-
Interferon-alpha and viral triggers promote functional maturation of human monocyte-derived dendritic cells
-
COI: 1:CAS:528:DC%2BD1cXmsV2hsrY%3D, PID: 18371115
-
Farkas A, Tonel G, Nestle FO (2008) Interferon-alpha and viral triggers promote functional maturation of human monocyte-derived dendritic cells. Br J Dermatol 158:921–929
-
(2008)
Br J Dermatol
, vol.158
, pp. 921-929
-
-
Farkas, A.1
Tonel, G.2
Nestle, F.O.3
-
37
-
-
84896320691
-
TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis
-
COI: 1:CAS:528:DC%2BC3sXhsl2gs7rE, PID: 24254490
-
Flutter B, Nestle FO (2013) TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis. Eur J Immunol 43:3138–3146
-
(2013)
Eur J Immunol
, vol.43
, pp. 3138-3146
-
-
Flutter, B.1
Nestle, F.O.2
-
38
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis
-
COI: 1:CAS:528:DC%2BD2cXlvFemtrY%3D, PID: 15194649
-
Franchimont D, Vermeire S, El Housni H, Pierik M, Van Steen K, Gustot T, Quertinmont E, Abramowicz M, Van Gossum A, Deviere J, Rutgeerts P (2004) Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis. Gut 53:987–992
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
Pierik, M.4
Van Steen, K.5
Gustot, T.6
Quertinmont, E.7
Abramowicz, M.8
Van Gossum, A.9
Deviere, J.10
Rutgeerts, P.11
-
39
-
-
39449127013
-
Expression of toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis
-
COI: 1:CAS:528:DC%2BD1cXisVaqsrk%3D, PID: 18040078
-
Frolova L, Drastich P, Rossmann P, Klimesova K, Tlaskalova-Hogenova H (2008) Expression of toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. J Histochem Cytochem 56:267–274
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 267-274
-
-
Frolova, L.1
Drastich, P.2
Rossmann, P.3
Klimesova, K.4
Tlaskalova-Hogenova, H.5
-
40
-
-
84930965559
-
How the intricate interaction among toll-like receptors, microbiota, and intestinal immunity can influence gastrointestinal pathology
-
PID: 26090491
-
Frosali S, Pagliari D, Gambassi G, Landolfi R, Pandolfi F, Cianci R (2015) How the intricate interaction among toll-like receptors, microbiota, and intestinal immunity can influence gastrointestinal pathology. J Immunol Res 2015:489821
-
(2015)
J Immunol Res
, vol.2015
, pp. 489821
-
-
Frosali, S.1
Pagliari, D.2
Gambassi, G.3
Landolfi, R.4
Pandolfi, F.5
Cianci, R.6
-
41
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
COI: 1:CAS:528:DC%2BD2MXktlSntr4%3D, PID: 15826931
-
Fukata M, Michelsen KS, Eri R, Thomas LS, Hu B, Lukasek K, Nast CC, Lechago J, Xu R, Naiki Y, Soliman A, Arditi M, Abreu MT (2005) Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol 288:G1055–G1065
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
, pp. G1055-G1065
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
Thomas, L.S.4
Hu, B.5
Lukasek, K.6
Nast, C.C.7
Lechago, J.8
Xu, R.9
Naiki, Y.10
Soliman, A.11
Arditi, M.12
Abreu, M.T.13
-
42
-
-
33845354405
-
Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis
-
COI: 1:CAS:528:DC%2BD28Xht1KksbjJ, PID: 17035347
-
Furuta T, Kikuchi T, Akira S, Watanabe N, Yoshikawa Y (2006) Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis. Int Immunol 18:1655–1662
-
(2006)
Int Immunol
, vol.18
, pp. 1655-1662
-
-
Furuta, T.1
Kikuchi, T.2
Akira, S.3
Watanabe, N.4
Yoshikawa, Y.5
-
43
-
-
32644438521
-
Innate and adaptive immunity and the pathophysiology of psoriasis
-
PID: 16488332
-
Gaspari AA (2006) Innate and adaptive immunity and the pathophysiology of psoriasis. J Am Acad Dermatol 54:S67–S80
-
(2006)
J Am Acad Dermatol
, vol.54
, pp. S67-S80
-
-
Gaspari, A.A.1
-
44
-
-
84905050462
-
Assembly and localization of toll-like receptor signalling complexes
-
COI: 1:CAS:528:DC%2BC2cXht1WksbnN, PID: 25060580
-
Gay NJ, Symmons MF, Gangloff M, Bryant CE (2014) Assembly and localization of toll-like receptor signalling complexes. Nat Rev Immunol 14:546–558
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 546-558
-
-
Gay, N.J.1
Symmons, M.F.2
Gangloff, M.3
Bryant, C.E.4
-
45
-
-
34548443465
-
Targeting toll-like receptors for drug development: a summary of commercial approaches
-
COI: 1:CAS:528:DC%2BD2sXpvFWgurw%3D, PID: 17667933
-
Gearing AJ (2007) Targeting toll-like receptors for drug development: a summary of commercial approaches. Immunol Cell Biol 85:490–494
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 490-494
-
-
Gearing, A.J.1
-
46
-
-
84886951561
-
Innate and adaptive immunity in inflammatory bowel disease
-
COI: 1:CAS:528:DC%2BC3sXhtFWis7%2FJ, PID: 23774107
-
Geremia A, Biancheri P, Allan P, Corazza GR, Di Sabatino A (2014) Innate and adaptive immunity in inflammatory bowel disease. Autoimmun Rev 13:3–10
-
(2014)
Autoimmun Rev
, vol.13
, pp. 3-10
-
-
Geremia, A.1
Biancheri, P.2
Allan, P.3
Corazza, G.R.4
Di Sabatino, A.5
-
47
-
-
10344256237
-
Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors
-
COI: 1:CAS:528:DC%2BD2MXjslSjtw%3D%3D, PID: 15611427
-
Gilliet M, Conrad C, Geiges M, Cozzio A, Thurlimann W, Burg G, Nestle FO, Dummer R (2004) Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 140:1490–1495
-
(2004)
Arch Dermatol
, vol.140
, pp. 1490-1495
-
-
Gilliet, M.1
Conrad, C.2
Geiges, M.3
Cozzio, A.4
Thurlimann, W.5
Burg, G.6
Nestle, F.O.7
Dummer, R.8
-
48
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
COI: 1:CAS:528:DC%2BC3cXlsVSgu7Y%3D, PID: 20303880
-
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140:918–934
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
49
-
-
84855163540
-
Intrinsic danger: activation of toll-like receptors in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC3MXhs12htLbP, PID: 21984766
-
Goh FG, Midwood KS (2012) Intrinsic danger: activation of toll-like receptors in rheumatoid arthritis. Rheumatology 51:7–23
-
(2012)
Rheumatology
, vol.51
, pp. 7-23
-
-
Goh, F.G.1
Midwood, K.S.2
-
50
-
-
77953723966
-
TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus
-
COI: 1:CAS:528:DC%2BC3cXnsVymtL8%3D, PID: 20559388
-
Guiducci C, Gong M, Xu Z, Gill M, Chaussabel D, Meeker T, Chan JH, Wright T, Punaro M, Bolland S, Soumelis V, Banchereau J, Coffman RL, Pascual V, Barrat FJ (2010) TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. Nature 465:937–941
-
(2010)
Nature
, vol.465
, pp. 937-941
-
-
Guiducci, C.1
Gong, M.2
Xu, Z.3
Gill, M.4
Chaussabel, D.5
Meeker, T.6
Chan, J.H.7
Wright, T.8
Punaro, M.9
Bolland, S.10
Soumelis, V.11
Banchereau, J.12
Coffman, R.L.13
Pascual, V.14
Barrat, F.J.15
-
51
-
-
64149087970
-
House dust mite allergen induces asthma via toll-like receptor 4 triggering of airway structural cells
-
COI: 1:CAS:528:DC%2BD1MXjslartrY%3D, PID: 19330007
-
Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN (2009) House dust mite allergen induces asthma via toll-like receptor 4 triggering of airway structural cells. Nat Med 15:410–416
-
(2009)
Nat Med
, vol.15
, pp. 410-416
-
-
Hammad, H.1
Chieppa, M.2
Perros, F.3
Willart, M.A.4
Germain, R.N.5
Lambrecht, B.N.6
-
52
-
-
77954946392
-
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
-
COI: 1:CAS:528:DC%2BC3cXovFCnt7Y%3D, PID: 20639876
-
Han C, Jin J, Xu S, Liu H, Li N, Cao X (2010) Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. Nat Immunol 11:734–742
-
(2010)
Nat Immunol
, vol.11
, pp. 734-742
-
-
Han, C.1
Jin, J.2
Xu, S.3
Liu, H.4
Li, N.5
Cao, X.6
-
54
-
-
84867412116
-
HMGB1 promotes the differentiation of Th17 via up-regulating TLR2 and IL-23 of CD14+ monocytes from patients with rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC38XhsVyksLzL, PID: 22809173
-
He Z, Shotorbani SS, Jiao Z, Su Z, Tong J, Liu Y, Shen P, Ma J, Gao J, Wang T, Xia S, Shao Q, Wang S, Xu H (2012) HMGB1 promotes the differentiation of Th17 via up-regulating TLR2 and IL-23 of CD14+ monocytes from patients with rheumatoid arthritis. Scand J Immunol 76:483–490
-
(2012)
Scand J Immunol
, vol.76
, pp. 483-490
-
-
He, Z.1
Shotorbani, S.S.2
Jiao, Z.3
Su, Z.4
Tong, J.5
Liu, Y.6
Shen, P.7
Ma, J.8
Gao, J.9
Wang, T.10
Xia, S.11
Shao, Q.12
Wang, S.13
Xu, H.14
-
55
-
-
38649129512
-
Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via toll-like receptors 2 and 4
-
PID: 17653282
-
Heimesaat MM, Fischer A, Siegmund B, Kupz A, Niebergall J, Fuchs D, Jahn HK, Freudenberg M, Loddenkemper C, Batra A, Lehr HA, Liesenfeld O, Blaut M, Gobel UB, Schumann RR, Bereswill S (2007) Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via toll-like receptors 2 and 4. PLoS One 2:e662
-
(2007)
PLoS One
, vol.2
-
-
Heimesaat, M.M.1
Fischer, A.2
Siegmund, B.3
Kupz, A.4
Niebergall, J.5
Fuchs, D.6
Jahn, H.K.7
Freudenberg, M.8
Loddenkemper, C.9
Batra, A.10
Lehr, H.A.11
Liesenfeld, O.12
Blaut, M.13
Gobel, U.B.14
Schumann, R.R.15
Bereswill, S.16
-
56
-
-
84923444904
-
Innate immunity in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2MXivVSktr0%3D, PID: 25689443
-
Heneka MT, Golenbock DT, Latz E (2015) Innate immunity in Alzheimer’s disease. Nat Immunol 16:229–236
-
(2015)
Nat Immunol
, vol.16
, pp. 229-236
-
-
Heneka, M.T.1
Golenbock, D.T.2
Latz, E.3
-
57
-
-
84863222361
-
A TLR 9 antagonist diminishes arthritis severity in a rat model of rheumatoid arthritis
-
Herman S, Fischer A, Pfatschbacher J, Hoffmann M, Steiner G (2011) A TLR 9 antagonist diminishes arthritis severity in a rat model of rheumatoid arthritis. Ann Rheum Dis 70:A39
-
(2011)
Ann Rheum Dis
, vol.70
, pp. A39
-
-
Herman, S.1
Fischer, A.2
Pfatschbacher, J.3
Hoffmann, M.4
Steiner, G.5
-
58
-
-
26444608592
-
Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease
-
PID: 16188043
-
Hoffjan S, Stemmler S, Parwez Q, Petrasch-Parwez E, Arinir U, Rohde G, Reinitz-Rademacher K, Schultze-Werninghaus G, Bufe A, Epplen JT (2005) Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. BMC Med Genet 6:34
-
(2005)
BMC Med Genet
, vol.6
, pp. 34
-
-
Hoffjan, S.1
Stemmler, S.2
Parwez, Q.3
Petrasch-Parwez, E.4
Arinir, U.5
Rohde, G.6
Reinitz-Rademacher, K.7
Schultze-Werninghaus, G.8
Bufe, A.9
Epplen, J.T.10
-
59
-
-
84921773771
-
The role of airway epithelial cells and innate immune cells in chronic respiratory disease
-
COI: 1:CAS:528:DC%2BC2cXhsFOksrrN, PID: 25234144
-
Holtzman MJ, Byers DE, Alexander-Brett J, Wang X (2014) The role of airway epithelial cells and innate immune cells in chronic respiratory disease. Nat Rev Immunol 14:686–698
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 686-698
-
-
Holtzman, M.J.1
Byers, D.E.2
Alexander-Brett, J.3
Wang, X.4
-
60
-
-
65249190995
-
Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling
-
COI: 1:CAS:528:DC%2BD1MXjvFOisro%3D, PID: 19342676
-
Huang QQ, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM 2nd, Tak PP, Haines GK 3rd, Nicchitta CV, Pope RM (2009) Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. J Immunol 182:4965–4973
-
(2009)
J Immunol
, vol.182
, pp. 4965-4973
-
-
Huang, Q.Q.1
Sobkoviak, R.2
Jockheck-Clark, A.R.3
Shi, B.4
Mandelin, A.M.5
Tak, P.P.6
Haines, G.K.7
Nicchitta, C.V.8
Pope, R.M.9
-
61
-
-
2342604896
-
Expression of toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD2cXkvFyku70%3D, PID: 15146415
-
Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, Ogawa N, Akashi S, Miyake K, Godowski PJ, Makino H (2004) Expression of toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis. Arthritis Rheum 50:1457–1467
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1457-1467
-
-
Iwahashi, M.1
Yamamura, M.2
Aita, T.3
Okamoto, A.4
Ueno, A.5
Ogawa, N.6
Akashi, S.7
Miyake, K.8
Godowski, P.J.9
Makino, H.10
-
62
-
-
0031739939
-
Introduction: the role of innate immunity in the adaptive immune response
-
PID: 9799708
-
Janeway CA Jr, Medzhitov R (1998) Introduction: the role of innate immunity in the adaptive immune response. Semin Immunol 10:349–350
-
(1998)
Semin Immunol
, vol.10
, pp. 349-350
-
-
Janeway, C.A.1
Medzhitov, R.2
-
63
-
-
84887015883
-
IMO-8400, a novel TLR7, TLR8 and TLR9 antagonist, inhibits disease development in mouse models of psoriasis (119.8)
-
Jiang A, Zhu F, Tang J, Kandimalla ER, La Monica N, Agrawal S (2012) IMO-8400, a novel TLR7, TLR8 and TLR9 antagonist, inhibits disease development in mouse models of psoriasis (119.8). J Immunol Res 188(119):8
-
(2012)
J Immunol Res
, vol.188
, Issue.119
, pp. 8
-
-
Jiang, A.1
Zhu, F.2
Tang, J.3
Kandimalla, E.R.4
La, M.N.5
Agrawal, S.6
-
64
-
-
48749128643
-
Structures of the toll-like receptor family and its ligand complexes
-
COI: 1:CAS:528:DC%2BD1cXhtVegtr3M, PID: 18701082
-
Jin MS, Lee JO (2008) Structures of the toll-like receptor family and its ligand complexes. Immunity 29:182–191
-
(2008)
Immunity
, vol.29
, pp. 182-191
-
-
Jin, M.S.1
Lee, J.O.2
-
65
-
-
45849105153
-
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer’s disease
-
Jin JJ, Kim HD, Maxwell JA, Li L, Fukuchi K (2008) Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer’s disease. J Neuroinflamm 5:23
-
(2008)
J Neuroinflamm
, vol.5
, pp. 23
-
-
Jin, J.J.1
Kim, H.D.2
Maxwell, J.A.3
Li, L.4
Fukuchi, K.5
-
66
-
-
10744223444
-
Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88
-
COI: 1:CAS:528:DC%2BD3sXptFOktr0%3D, PID: 14634130
-
Joosten LA, Koenders MI, Smeets RL, Heuvelmans-Jacobs M, Helsen MM, Takeda K, Akira S, Lubberts E, Van De Loo FA, Van Den Berg WB (2003) Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88. J Immunol 171:6145–6153
-
(2003)
J Immunol
, vol.171
, pp. 6145-6153
-
-
Joosten, L.A.1
Koenders, M.I.2
Smeets, R.L.3
Heuvelmans-Jacobs, M.4
Helsen, M.M.5
Takeda, K.6
Akira, S.7
Lubberts, E.8
Van De Loo, F.A.9
Van Den Berg, W.B.10
-
67
-
-
84876067752
-
Design, synthesis and biological evaluation of novel antagonist compounds of toll-like receptors 7, 8 and 9
-
COI: 1:CAS:528:DC%2BC3sXlsVCntbo%3D, PID: 23396449
-
Kandimalla ER, Bhagat L, Wang D, Yu D, Sullivan T, La Monica N, Agrawal S (2013) Design, synthesis and biological evaluation of novel antagonist compounds of toll-like receptors 7, 8 and 9. Nucleic Acids Res 41:3947–3961
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 3947-3961
-
-
Kandimalla, E.R.1
Bhagat, L.2
Wang, D.3
Yu, D.4
Sullivan, T.5
La Monica, N.6
Agrawal, S.7
-
68
-
-
13444274668
-
Toll-like receptor downstream signaling
-
COI: 1:CAS:528:DC%2BD2MXmtVymsw%3D%3D, PID: 15642149
-
Kawai T, Akira S (2005) Toll-like receptor downstream signaling. Arthritis Res Ther 7:12–19
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 12-19
-
-
Kawai, T.1
Akira, S.2
-
70
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on toll-like receptors
-
COI: 1:CAS:528:DC%2BC3cXkvFSjsrc%3D, PID: 20404851
-
Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on toll-like receptors. Nat Immunol 11:373–384
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
71
-
-
84918564833
-
Toll-like receptor signaling pathways
-
PID: 25309543
-
Kawasaki T, Kawai T (2014) Toll-like receptor signaling pathways. Front Immunol 5:461
-
(2014)
Front Immunol
, vol.5
, pp. 461
-
-
Kawasaki, T.1
Kawai, T.2
-
72
-
-
36448943427
-
DUBA: a deubiquitinase that regulates type I interferon production
-
COI: 1:CAS:528:DC%2BD2sXhtlyrsrrI, PID: 17991829
-
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O’rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM (2007) DUBA: a deubiquitinase that regulates type I interferon production. Science 318:1628–1632
-
(2007)
Science
, vol.318
, pp. 1628-1632
-
-
Kayagaki, N.1
Phung, Q.2
Chan, S.3
Chaudhari, R.4
Quan, C.5
O’rourke, K.M.6
Eby, M.7
Pietras, E.8
Cheng, G.9
Bazan, J.F.10
Zhang, Z.11
Arnott, D.12
Dixit, V.M.13
-
73
-
-
79959773879
-
Toll-like receptors as targets for immune disorders
-
COI: 1:CAS:528:DC%2BC3MXotl2hs7g%3D, PID: 21529972
-
Keogh B, Parker AE (2011) Toll-like receptors as targets for immune disorders. Trends Pharmacol Sci 32:435–442
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 435-442
-
-
Keogh, B.1
Parker, A.E.2
-
74
-
-
0037178785
-
IRAK-M is a negative regulator of toll-like receptor signaling
-
COI: 1:CAS:528:DC%2BD38XlvV2htrw%3D, PID: 12150927
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA (2002) IRAK-M is a negative regulator of toll-like receptor signaling. Cell 110:191–202
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway, C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
75
-
-
46049084570
-
Toll-like receptor heterodimer variants protect from childhood asthma
-
COI: 1:CAS:528:DC%2BD1cXotlajtL0%3D, PID: 18547625
-
Kormann MS, Depner M, Hartl D, Klopp N, Illig T, Adamski J, Vogelberg C, Weiland SK, Von Mutius E, Kabesch M (2008) Toll-like receptor heterodimer variants protect from childhood asthma. J Allergy Clin Immunol 122:86–92
-
(2008)
J Allergy Clin Immunol
, vol.122
, pp. 86-92
-
-
Kormann, M.S.1
Depner, M.2
Hartl, D.3
Klopp, N.4
Illig, T.5
Adamski, J.6
Vogelberg, C.7
Weiland, S.K.8
Von Mutius, E.9
Kabesch, M.10
-
76
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
COI: 1:CAS:528:DC%2BC3MXmtVCltw%3D%3D, PID: 21235323
-
Kumar H, Kawai T, Akira S (2011) Pathogen recognition by the innate immune system. Int Rev Immunol 30:16–34
-
(2011)
Int Rev Immunol
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
77
-
-
84894063872
-
Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo
-
PID: 24342772
-
Lamphier M, Zheng W, Latz E, Spyvee M, Hansen H, Rose J, Genest M, Yang H, Shaffer C, Zhao Y, Shen Y, Liu C, Liu D, Mempel TR, Rowbottom C, Chow J, Twine NC, Yu M, Gusovsky F, Ishizaka ST (2014) Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol 85:429–440
-
(2014)
Mol Pharmacol
, vol.85
, pp. 429-440
-
-
Lamphier, M.1
Zheng, W.2
Latz, E.3
Spyvee, M.4
Hansen, H.5
Rose, J.6
Genest, M.7
Yang, H.8
Shaffer, C.9
Zhao, Y.10
Shen, Y.11
Liu, C.12
Liu, D.13
Mempel, T.R.14
Rowbottom, C.15
Chow, J.16
Twine, N.C.17
Yu, M.18
Gusovsky, F.19
Ishizaka, S.T.20
more..
-
78
-
-
75949119017
-
Toll-like receptors in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3cXisVamt7w%3D, PID: 19688332
-
Landreth GE, Reed-Geaghan EG (2009) Toll-like receptors in Alzheimer’s disease. Curr Top Microbiol Immunol 336:137–153
-
(2009)
Curr Top Microbiol Immunol
, vol.336
, pp. 137-153
-
-
Landreth, G.E.1
Reed-Geaghan, E.G.2
-
79
-
-
0037791839
-
Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18
-
COI: 1:CAS:528:DC%2BD3sXkvF2rsLg%3D, PID: 12787126
-
Lebre MC, Antons JC, Kalinski P, Schuitemaker JH, Van Capel TM, Kapsenberg ML, De Jong EC (2003) Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18. J Invest Dermatol 120:990–997
-
(2003)
J Invest Dermatol
, vol.120
, pp. 990-997
-
-
Lebre, M.C.1
Antons, J.C.2
Kalinski, P.3
Schuitemaker, J.H.4
Van Capel, T.M.5
Kapsenberg, M.L.6
De Jong, E.C.7
-
80
-
-
59649107055
-
TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus
-
COI: 1:CAS:528:DC%2BD1MXosFCm, PID: 19047436
-
Lee PY, Kumagai Y, Li Y, Takeuchi O, Yoshida H, Weinstein J, Kellner ES, Nacionales D, Barker T, Kelly-Scumpia K, Van Rooijen N, Kumar H, Kawai T, Satoh M, Akira S, Reeves WH (2008) TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus. J Exp Med 205:2995–3006
-
(2008)
J Exp Med
, vol.205
, pp. 2995-3006
-
-
Lee, P.Y.1
Kumagai, Y.2
Li, Y.3
Takeuchi, O.4
Yoshida, H.5
Weinstein, J.6
Kellner, E.S.7
Nacionales, D.8
Barker, T.9
Kelly-Scumpia, K.10
Van Rooijen, N.11
Kumar, H.12
Kawai, T.13
Satoh, M.14
Akira, S.15
Reeves, W.H.16
-
81
-
-
77954840281
-
Activation of toll-like receptors 2, 3 or 5 induces matrix metalloproteinase-1 and -9 expression with the involvement of MAPKs and NF-kappaB in human epidermal keratinocytes
-
PID: 19758322
-
Lee Y, Kim H, Kim S, Kim KH, Chung JH (2010) Activation of toll-like receptors 2, 3 or 5 induces matrix metalloproteinase-1 and -9 expression with the involvement of MAPKs and NF-kappaB in human epidermal keratinocytes. Exp Dermatol 19:e44–e49
-
(2010)
Exp Dermatol
, vol.19
, pp. e44-e49
-
-
Lee, Y.1
Kim, H.2
Kim, S.3
Kim, K.H.4
Chung, J.H.5
-
82
-
-
84862804952
-
Accessory molecules for toll-like receptors and their function
-
COI: 1:CAS:528:DC%2BC38Xhs1Ggs7o%3D, PID: 22301850
-
Lee CC, Avalos AM, Ploegh HL (2012) Accessory molecules for toll-like receptors and their function. Nat Rev Immunol 12:168–179
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 168-179
-
-
Lee, C.C.1
Avalos, A.M.2
Ploegh, H.L.3
-
83
-
-
84963595737
-
Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update
-
COI: 1:CAS:528:DC%2BC28Xht1ens73L, PID: 26762473
-
Lee YH, Choi SJ, Ji JD, Song GG (2016) Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update. Lupus 25:593–601
-
(2016)
Lupus
, vol.25
, pp. 593-601
-
-
Lee, Y.H.1
Choi, S.J.2
Ji, J.D.3
Song, G.G.4
-
84
-
-
84861577379
-
An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration
-
COI: 1:CAS:528:DC%2BC38XntF2hu7w%3D, PID: 22610069
-
Lehmann SM, Kruger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kalin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S (2012) An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration. Nat Neurosci 15:827–835
-
(2012)
Nat Neurosci
, vol.15
, pp. 827-835
-
-
Lehmann, S.M.1
Kruger, C.2
Park, B.3
Derkow, K.4
Rosenberger, K.5
Baumgart, J.6
Trimbuch, T.7
Eom, G.8
Hinz, M.9
Kaul, D.10
Habbel, P.11
Kalin, R.12
Franzoni, E.13
Rybak, A.14
Nguyen, D.15
Veh, R.16
Ninnemann, O.17
Peters, O.18
Nitsch, R.19
Heppner, F.L.20
Golenbock, D.21
Schott, E.22
Ploegh, H.L.23
Wulczyn, F.G.24
Lehnardt, S.25
more..
-
85
-
-
38449117668
-
TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia
-
COI: 1:CAS:528:DC%2BD2sXhtFyksr%2FP, PID: 17947688
-
Lehnardt S, Wennekamp J, Freyer D, Liedtke C, Krueger C, Nitsch R, Bechmann I, Weber JR, Henneke P (2007) TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia. J Immunol 179:6134–6143
-
(2007)
J Immunol
, vol.179
, pp. 6134-6143
-
-
Lehnardt, S.1
Wennekamp, J.2
Freyer, D.3
Liedtke, C.4
Krueger, C.5
Nitsch, R.6
Bechmann, I.7
Weber, J.R.8
Henneke, P.9
-
86
-
-
79951811761
-
A novel antagonist of TLR9 blocking all classes of immunostimulatory CpG-ODNs
-
COI: 1:CAS:528:DC%2BC3MXisFehtLY%3D, PID: 21036131
-
Li Y, Cao H, Wang N, Xiang Y, Lu Y, Zhao K, Zheng J, Zhou H (2011) A novel antagonist of TLR9 blocking all classes of immunostimulatory CpG-ODNs. Vaccine 29:2193–2198
-
(2011)
Vaccine
, vol.29
, pp. 2193-2198
-
-
Li, Y.1
Cao, H.2
Wang, N.3
Xiang, Y.4
Lu, Y.5
Zhao, K.6
Zheng, J.7
Zhou, H.8
-
87
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
COI: 1:CAS:528:DC%2BD2MXks1GmsLo%3D, PID: 15928677
-
Liew FY, Xu D, Brint EK, O’neill LA (2005) Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol 5:446–458
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O’neill, L.A.4
-
88
-
-
77954750715
-
ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance
-
COI: 1:CAS:528:DC%2BC3cXls1WisLc%3D, PID: 20400705
-
Liu J, Buckley JM, Redmond HP, Wang JH (2010) ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance. J Immunol 184:5802–5808
-
(2010)
J Immunol
, vol.184
, pp. 5802-5808
-
-
Liu, J.1
Buckley, J.M.2
Redmond, H.P.3
Wang, J.H.4
-
89
-
-
84983156817
-
TLR4 antagonist attenuates atherogenesis in LDL receptor-deficient mice with diet-induced type 2 diabetes
-
COI: 1:CAS:528:DC%2BC2MXhtFels7jN, PID: 26162692
-
Lu Z, Zhang X, Li Y, Lopes-Virella MF, Huang Y (2015) TLR4 antagonist attenuates atherogenesis in LDL receptor-deficient mice with diet-induced type 2 diabetes. Immunobiology 220:1246–1254
-
(2015)
Immunobiology
, vol.220
, pp. 1246-1254
-
-
Lu, Z.1
Zhang, X.2
Li, Y.3
Lopes-Virella, M.F.4
Huang, Y.5
-
90
-
-
67349097405
-
Expression and functional analysis of toll-like receptors of peripheral blood cells in asthmatic patients: implication for immunopathological mechanism in asthma
-
COI: 1:CAS:528:DC%2BD1MXlslCntrs%3D, PID: 19067129
-
Lun SW, Wong CK, Ko FW, Hui DS, Lam CW (2009) Expression and functional analysis of toll-like receptors of peripheral blood cells in asthmatic patients: implication for immunopathological mechanism in asthma. J Clin Immunol 29:330–342
-
(2009)
J Clin Immunol
, vol.29
, pp. 330-342
-
-
Lun, S.W.1
Wong, C.K.2
Ko, F.W.3
Hui, D.S.4
Lam, C.W.5
-
91
-
-
84878089733
-
Curcumin attenuates allergic airway inflammation by regulation of CD4+ CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice
-
COI: 1:CAS:528:DC%2BC3sXovVWhsbk%3D, PID: 23500387
-
Ma C, Ma Z, Fu Q, Ma S (2013) Curcumin attenuates allergic airway inflammation by regulation of CD4+ CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice. Fitoterapia 87:57–64
-
(2013)
Fitoterapia
, vol.87
, pp. 57-64
-
-
Ma, C.1
Ma, Z.2
Fu, Q.3
Ma, S.4
-
92
-
-
31344467156
-
Suppressor of cytokine signaling 1 negatively regulates toll-like receptor signaling by mediating Mal degradation
-
COI: 1:CAS:528:DC%2BD28Xlt1ertg%3D%3D, PID: 16415872
-
Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ, Nicholson SE, Hilton DJ, O’neill LA, Hertzog PJ (2006) Suppressor of cytokine signaling 1 negatively regulates toll-like receptor signaling by mediating Mal degradation. Nat Immunol 7:148–155
-
(2006)
Nat Immunol
, vol.7
, pp. 148-155
-
-
Mansell, A.1
Smith, R.2
Doyle, S.L.3
Gray, P.4
Fenner, J.E.5
Crack, P.J.6
Nicholson, S.E.7
Hilton, D.J.8
O’neill, L.A.9
Hertzog, P.J.10
-
93
-
-
78651300299
-
TAK-242 (resatorvid), a small-molecule inhibitor of toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules
-
COI: 1:CAS:528:DC%2BC3MXls1ehuw%3D%3D, PID: 20881006
-
Matsunaga N, Tsuchimori N, Matsumoto T, Ii M (2011) TAK-242 (resatorvid), a small-molecule inhibitor of toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Mol Pharmacol 79:34–41
-
(2011)
Mol Pharmacol
, vol.79
, pp. 34-41
-
-
Matsunaga, N.1
Tsuchimori, N.2
Matsumoto, T.3
Ii, M.4
-
94
-
-
78149492075
-
State-of-the-art: rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC3cXhsFakur3K, PID: 20959326
-
Mcinnes IB, O’dell JR (2010) State-of-the-art: rheumatoid arthritis. Ann Rheum Dis 69:1898–1906
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1898-1906
-
-
Mcinnes, I.B.1
O’dell, J.R.2
-
95
-
-
22144443170
-
The role of toll-like receptors in the pathogenesis and treatment of dermatological disease
-
COI: 1:CAS:528:DC%2BD2MXmvVyku78%3D, PID: 15982296
-
Mcinturff JE, Modlin RL, Kim J (2005) The role of toll-like receptors in the pathogenesis and treatment of dermatological disease. J Investig Dermatol 125:1–8
-
(2005)
J Investig Dermatol
, vol.125
, pp. 1-8
-
-
Mcinturff, J.E.1
Modlin, R.L.2
Kim, J.3
-
96
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
COI: 1:CAS:528:DC%2BD2sXhtFOjt7nN, PID: 17943118
-
Medzhitov R (2007) Recognition of microorganisms and activation of the immune response. Nature 449:819–826
-
(2007)
Nature
, vol.449
, pp. 819-826
-
-
Medzhitov, R.1
-
97
-
-
77952483341
-
Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
-
PID: 20500834
-
Meng L, Zhu W, Jiang C, He X, Hou W, Zheng F, Holmdahl R, Lu S (2010) Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. Arthritis Res Ther 12:R103
-
(2010)
Arthritis Res Ther
, vol.12
, pp. R103
-
-
Meng, L.1
Zhu, W.2
Jiang, C.3
He, X.4
Hou, W.5
Zheng, F.6
Holmdahl, R.7
Lu, S.8
-
98
-
-
44049098939
-
IRAK2 takes its place in TLR signaling
-
COI: 1:CAS:528:DC%2BD1cXmtVWqu7g%3D, PID: 18490904
-
Meylan E, Tschopp J (2008) IRAK2 takes its place in TLR signaling. Nat Immunol 9:581–582
-
(2008)
Nat Immunol
, vol.9
, pp. 581-582
-
-
Meylan, E.1
Tschopp, J.2
-
99
-
-
20844445114
-
TGF-alpha regulates TLR expression and function on epidermal keratinocytes
-
COI: 1:CAS:528:DC%2BD2MXjvV2mt7s%3D, PID: 15879109
-
Miller LS, Sorensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL (2005) TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol 174:6137–6143
-
(2005)
J Immunol
, vol.174
, pp. 6137-6143
-
-
Miller, L.S.1
Sorensen, O.E.2
Liu, P.T.3
Jalian, H.R.4
Eshtiaghpour, D.5
Behmanesh, B.E.6
Chung, W.7
Starner, T.D.8
Kim, J.9
Sieling, P.A.10
Ganz, T.11
Modlin, R.L.12
-
100
-
-
84881397595
-
Cleavage of fibrinogen by proteinases elicits allergic responses through toll-like receptor 4
-
COI: 1:CAS:528:DC%2BC3sXht1GhurvI, PID: 23950537
-
Millien VO, Lu W, Shaw J, Yuan X, Mak G, Roberts L, Song LZ, Knight JM, Creighton CJ, Luong A, Kheradmand F, Corry DB (2013) Cleavage of fibrinogen by proteinases elicits allergic responses through toll-like receptor 4. Science 341:792–796
-
(2013)
Science
, vol.341
, pp. 792-796
-
-
Millien, V.O.1
Lu, W.2
Shaw, J.3
Yuan, X.4
Mak, G.5
Roberts, L.6
Song, L.Z.7
Knight, J.M.8
Creighton, C.J.9
Luong, A.10
Kheradmand, F.11
Corry, D.B.12
-
101
-
-
79960536837
-
Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BC3MXos1ehsrw%3D, PID: 21685327
-
Miranda-Hernandez S, Gerlach N, Fletcher JM, Biros E, Mack M, Korner H, Baxter AG (2011) Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. J Immunol 187:791–804
-
(2011)
J Immunol
, vol.187
, pp. 791-804
-
-
Miranda-Hernandez, S.1
Gerlach, N.2
Fletcher, J.M.3
Biros, E.4
Mack, M.5
Korner, H.6
Baxter, A.G.7
-
102
-
-
84928672154
-
Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain
-
COI: 1:CAS:528:DC%2BC2MXmsFShtb0%3D, PID: 25870276
-
Mistry P, Laird MH, Schwarz RS, Greene S, Dyson T, Snyder GA, Xiao TS, Chauhan J, Fletcher S, Toshchakov VY, Mackerell AD Jr, Vogel SN (2015) Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proc Natl Acad Sci USA 112:5455–5460
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 5455-5460
-
-
Mistry, P.1
Laird, M.H.2
Schwarz, R.S.3
Greene, S.4
Dyson, T.5
Snyder, G.A.6
Xiao, T.S.7
Chauhan, J.8
Fletcher, S.9
Toshchakov, V.Y.10
Mackerell, A.D.11
Vogel, S.N.12
-
103
-
-
33645086385
-
The toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis
-
COI: 1:CAS:528:DC%2BD28XjsFaktrY%3D, PID: 16487238
-
Montes AH, Asensi V, Alvarez V, Valle E, Ocana MG, Meana A, Carton JA, Paz J, Fierer J, Celada A (2006) The toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis. Clin Exp Immunol 143:404–413
-
(2006)
Clin Exp Immunol
, vol.143
, pp. 404-413
-
-
Montes, A.H.1
Asensi, V.2
Alvarez, V.3
Valle, E.4
Ocana, M.G.5
Meana, A.6
Carton, J.A.7
Paz, J.8
Fierer, J.9
Celada, A.10
-
104
-
-
78650967552
-
Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts
-
COI: 1:CAS:528:DC%2BC3MXltl2gtg%3D%3D, PID: 21179282
-
Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, Park KS, Kim HY, Park SH (2010) Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts. Korean J Intern Med 25:429–435
-
(2010)
Korean J Intern Med
, vol.25
, pp. 429-435
-
-
Moon, S.J.1
Park, M.K.2
Oh, H.J.3
Lee, S.Y.4
Kwok, S.K.5
Cho, M.L.6
Ju, J.H.7
Park, K.S.8
Kim, H.Y.9
Park, S.H.10
-
105
-
-
84880174760
-
The role of toll-like receptor proteins (TLR) 2 and 4 in mediating inflammation in proximal tubules
-
COI: 1:CAS:528:DC%2BC3sXht1OmtrjL, PID: 23576640
-
Mudaliar H, Pollock C, Komala MG, Chadban S, Wu H, Panchapakesan U (2013) The role of toll-like receptor proteins (TLR) 2 and 4 in mediating inflammation in proximal tubules. Am J Physiol Renal Physiol 305:F143–F154
-
(2013)
Am J Physiol Renal Physiol
, vol.305
, pp. F143-F154
-
-
Mudaliar, H.1
Pollock, C.2
Komala, M.G.3
Chadban, S.4
Wu, H.5
Panchapakesan, U.6
-
106
-
-
0037372661
-
Inhibition of endotoxin response by e5564, a novel toll-like receptor 4-directed endotoxin antagonist
-
COI: 1:CAS:528:DC%2BD3sXit1eisrg%3D, PID: 12604686
-
Mullarkey M, Rose JR, Bristol J, Kawata T, Kimura A, Kobayashi S, Przetak M, Chow J, Gusovsky F, Christ WJ, Rossignol DP (2003) Inhibition of endotoxin response by e5564, a novel toll-like receptor 4-directed endotoxin antagonist. J Pharmacol Exp Ther 304:1093–1102
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1093-1102
-
-
Mullarkey, M.1
Rose, J.R.2
Bristol, J.3
Kawata, T.4
Kimura, A.5
Kobayashi, S.6
Przetak, M.7
Chow, J.8
Gusovsky, F.9
Christ, W.J.10
Rossignol, D.P.11
-
107
-
-
84905665143
-
Toll-like receptor 4 in inflammation and angiogenesis: a double-edged sword
-
PID: 25071774
-
Murad S (2014) Toll-like receptor 4 in inflammation and angiogenesis: a double-edged sword. Front Immunol 5:313
-
(2014)
Front Immunol
, vol.5
, pp. 313
-
-
Murad, S.1
-
108
-
-
70349448402
-
Skin immune sentinels in health and disease
-
COI: 1:CAS:528:DC%2BD1MXhtFGjt7nO, PID: 19763149
-
Nestle FO, Di Meglio P, Qin JZ, Nickoloff BJ (2009) Skin immune sentinels in health and disease. Nat Rev Immunol 9:679–691
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 679-691
-
-
Nestle, F.O.1
Di Meglio, P.2
Qin, J.Z.3
Nickoloff, B.J.4
-
109
-
-
77949903821
-
TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
-
COI: 1:CAS:528:DC%2BC3cXhsVGlur8%3D, PID: 20089701
-
Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K, Shlomchik MJ (2010) TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus. J Immunol 184:1840–1848
-
(2010)
J Immunol
, vol.184
, pp. 1840-1848
-
-
Nickerson, K.M.1
Christensen, S.R.2
Shupe, J.3
Kashgarian, M.4
Kim, D.5
Elkon, K.6
Shlomchik, M.J.7
-
110
-
-
84924565569
-
Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses
-
PID: 25681333
-
Nundel K, Green NM, Shaffer AL, Moody KL, Busto P, Eilat D, Miyake K, Oropallo MA, Cancro MP, Marshak-Rothstein A (2015) Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses. J Immunol 194:2504–2512
-
(2015)
J Immunol
, vol.194
, pp. 2504-2512
-
-
Nundel, K.1
Green, N.M.2
Shaffer, A.L.3
Moody, K.L.4
Busto, P.5
Eilat, D.6
Miyake, K.7
Oropallo, M.A.8
Cancro, M.P.9
Marshak-Rothstein, A.10
-
111
-
-
67649422321
-
Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer
-
PID: 19474110
-
O’neill LA, Bryant CE, Doyle SL (2009) Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol Rev 61:177–197
-
(2009)
Pharmacol Rev
, vol.61
, pp. 177-197
-
-
O’neill, L.A.1
Bryant, C.E.2
Doyle, S.L.3
-
112
-
-
84875124740
-
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial
-
COI: 1:CAS:528:DC%2BC3sXltlyqt7o%3D, PID: 23512062
-
Opal SM, Laterre PF, Francois B, Larosa SP, Angus DC, Mira JP, Wittebole X, Dugernier T, Dugernier D, Tidswell M, Jauregui L, Krell K, Pachl J, Takahashi T, Peckelsen C, Cordasco E, Chang CS, Oeyen S, Aikawa N, Maruyama T, Schein R, Kalil AC, Van Nuffelen M, Lynn M, Rossignol DP, Gogate J, Roberts MB, Wheeler JL, Vincent JL, Vincent AS (2013) Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA 309:1154–1162
-
(2013)
JAMA
, vol.309
, pp. 1154-1162
-
-
Opal, S.M.1
Laterre, P.F.2
Francois, B.3
Larosa, S.P.4
Angus, D.C.5
Mira, J.P.6
Wittebole, X.7
Dugernier, T.8
Dugernier, D.9
Tidswell, M.10
Jauregui, L.11
Krell, K.12
Pachl, J.13
Takahashi, T.14
Peckelsen, C.15
Cordasco, E.16
Chang, C.S.17
Oeyen, S.18
Aikawa, N.19
Maruyama, T.20
Schein, R.21
Kalil, A.C.22
Van Nuffelen, M.23
Lynn, M.24
Rossignol, D.P.25
Gogate, J.26
Roberts, M.B.27
Wheeler, J.L.28
Vincent, J.L.29
Vincent, A.S.30
more..
-
113
-
-
77649180575
-
TLRs and chronic inflammation
-
COI: 1:CAS:528:DC%2BC3cXivFKitLg%3D, PID: 19840864
-
Ospelt C, Gay S (2010) TLRs and chronic inflammation. Int J Biochem Cell Biol 42:495–505
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 495-505
-
-
Ospelt, C.1
Gay, S.2
-
114
-
-
57349192121
-
Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis
-
COI: 1:CAS:528:DC%2BD1MXmt1ymsg%3D%3D, PID: 19035519
-
Ospelt C, Brentano F, Rengel Y, Stanczyk J, Kolling C, Tak PP, Gay RE, Gay S, Kyburz D (2008) Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis. Arthritis Rheum 58:3684–3692
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3684-3692
-
-
Ospelt, C.1
Brentano, F.2
Rengel, Y.3
Stanczyk, J.4
Kolling, C.5
Tak, P.P.6
Gay, R.E.7
Gay, S.8
Kyburz, D.9
-
115
-
-
67349092199
-
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway
-
COI: 1:CAS:528:DC%2BD1MXltlSrsbs%3D, PID: 19412184
-
Palsson-Mcdermott EM, Doyle SL, Mcgettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O’neill LA (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nat Immunol 10:579–586
-
(2009)
Nat Immunol
, vol.10
, pp. 579-586
-
-
Palsson-Mcdermott, E.M.1
Doyle, S.L.2
Mcgettrick, A.F.3
Hardy, M.4
Husebye, H.5
Banahan, K.6
Gong, M.7
Golenbock, D.8
Espevik, T.9
O’neill, L.A.10
-
116
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
COI: 1:CAS:528:DC%2BD2cXhsFaqurc%3D, PID: 14660645
-
Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, Abraham E (2004) Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279:7370–7377
-
(2004)
J Biol Chem
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
Kim, J.Y.4
Strassheim, D.5
Ishizaka, A.6
Abraham, E.7
-
117
-
-
84961938225
-
Inflammation: species-specific TLR signalling—insight into human disease
-
COI: 1:CAS:528:DC%2BC28XkvVyhsb0%3D, PID: 27006311
-
Perkins DJ, Vogel SN (2016) Inflammation: species-specific TLR signalling—insight into human disease. Nat Rev Rheumatol 12:198–200
-
(2016)
Nat Rev Rheumatol
, vol.12
, pp. 198-200
-
-
Perkins, D.J.1
Vogel, S.N.2
-
118
-
-
84856376035
-
A synthetic lipid A mimetic modulates human TLR4 activity
-
COI: 1:CAS:528:DC%2BC3MXhsFGkur3O, PID: 22140087
-
Piazza M, Calabrese V, Damore G, Cighetti R, Gioannini T, Weiss J, Peri F (2012) A synthetic lipid A mimetic modulates human TLR4 activity. ChemMedChem 7:213–217
-
(2012)
ChemMedChem
, vol.7
, pp. 213-217
-
-
Piazza, M.1
Calabrese, V.2
Damore, G.3
Cighetti, R.4
Gioannini, T.5
Weiss, J.6
Peri, F.7
-
119
-
-
77955383770
-
DAMPening inflammation by modulating TLR signalling
-
PID: 20706656
-
Piccinini AM, Midwood KS (2010) DAMPening inflammation by modulating TLR signalling. Mediators Inflamm 2010:672395
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 672395
-
-
Piccinini, A.M.1
Midwood, K.S.2
-
120
-
-
80051755778
-
Toll-like receptor 4 is involved in inflammatory and joint destructive pathways in collagen-induced arthritis in DBA1 J mice
-
COI: 1:CAS:528:DC%2BC3MXhtFKmsb7I, PID: 21858160
-
Pierer M, Wagner U, Rossol M, Ibrahim S (2011) Toll-like receptor 4 is involved in inflammatory and joint destructive pathways in collagen-induced arthritis in DBA1 J mice. PLoS One 6:e23539
-
(2011)
PLoS One
, vol.6
-
-
Pierer, M.1
Wagner, U.2
Rossol, M.3
Ibrahim, S.4
-
121
-
-
26444552110
-
Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon
-
COI: 1:CAS:528:DC%2BD2MXhtFWisbrM, PID: 16188991
-
Prehaud C, Megret F, Lafage M, Lafon M (2005) Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon. J Virol 79:12893–12904
-
(2005)
J Virol
, vol.79
, pp. 12893-12904
-
-
Prehaud, C.1
Megret, F.2
Lafage, M.3
Lafon, M.4
-
122
-
-
84876795008
-
Regulation of toll-like receptor signaling pathways in innate immune responses
-
COI: 1:CAS:528:DC%2BC3sXosVClsbg%3D, PID: 23163321
-
Qian C, Cao X (2013) Regulation of toll-like receptor signaling pathways in innate immune responses. Ann N Y Acad Sci 1283:67–74
-
(2013)
Ann N Y Acad Sci
, vol.1283
, pp. 67-74
-
-
Qian, C.1
Cao, X.2
-
123
-
-
10444278132
-
Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma
-
COI: 1:CAS:528:DC%2BD2MXls1egsw%3D%3D, PID: 15593217
-
Radstake TR, Roelofs MF, Jenniskens YM, Oppers-Walgreen B, Van Riel PL, Barrera P, Joosten LA, Van Den Berg WB (2004) Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma. Arthritis Rheum 50:3856–3865
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3856-3865
-
-
Radstake, T.R.1
Roelofs, M.F.2
Jenniskens, Y.M.3
Oppers-Walgreen, B.4
Van Riel, P.L.5
Barrera, P.6
Joosten, L.A.7
Van Den Berg, W.B.8
-
124
-
-
84887923682
-
A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation
-
PID: 23475791
-
Ramani V, Madhusoodhanan R, Kosanke S, Awasthi S (2013) A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation. Innate Immun 19:596–610
-
(2013)
Innate Immun
, vol.19
, pp. 596-610
-
-
Ramani, V.1
Madhusoodhanan, R.2
Kosanke, S.3
Awasthi, S.4
-
125
-
-
33745324477
-
TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response
-
COI: 1:CAS:528:DC%2BD28XlvV2ntr4%3D, PID: 16785525
-
Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL (2006) TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. J Immunol 177:298–305
-
(2006)
J Immunol
, vol.177
, pp. 298-305
-
-
Renn, C.N.1
Sanchez, D.J.2
Ochoa, M.T.3
Legaspi, A.J.4
Oh, C.K.5
Liu, P.T.6
Krutzik, S.R.7
Sieling, P.A.8
Cheng, G.9
Modlin, R.L.10
-
126
-
-
23644449245
-
The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells
-
COI: 1:CAS:528:DC%2BD2MXpslGhtro%3D, PID: 16052591
-
Roelofs MF, Joosten LA, Abdollahi-Roodsaz S, Van Lieshout AW, Sprong T, Van Den Hoogen FH, Van Den Berg WB, Radstake TR (2005) The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells. Arthritis Rheum 52:2313–2322
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2313-2322
-
-
Roelofs, M.F.1
Joosten, L.A.2
Abdollahi-Roodsaz, S.3
Van Lieshout, A.W.4
Sprong, T.5
Van Den Hoogen, F.H.6
Van Den Berg, W.B.7
Radstake, T.R.8
-
127
-
-
33646882893
-
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD28XkslWgsro%3D, PID: 16709864
-
Roelofs MF, Boelens WC, Joosten LA, Abdollahi-Roodsaz S, Geurts J, Wunderink LU, Schreurs BW, Van Den Berg WB, Radstake TR (2006) Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. J Immunol 176:7021–7027
-
(2006)
J Immunol
, vol.176
, pp. 7021-7027
-
-
Roelofs, M.F.1
Boelens, W.C.2
Joosten, L.A.3
Abdollahi-Roodsaz, S.4
Geurts, J.5
Wunderink, L.U.6
Schreurs, B.W.7
Van Den Berg, W.B.8
Radstake, T.R.9
-
128
-
-
84866058423
-
TLR9 is important for protection against intestinal damage and for intestinal repair
-
PID: 22893852
-
Rose WA 2nd, Sakamoto K, Leifer CA (2012) TLR9 is important for protection against intestinal damage and for intestinal repair. Sci Rep 2:574
-
(2012)
Sci Rep
, vol.2
, pp. 574
-
-
Rose, W.A.1
Sakamoto, K.2
Leifer, C.A.3
-
129
-
-
36849033963
-
TAM receptors are pleiotropic inhibitors of the innate immune response
-
COI: 1:CAS:528:DC%2BD1cXksFGgug%3D%3D, PID: 18083102
-
Rothlin CV, Ghosh S, Zuniga EI, Oldstone MBA, Lemke G (2007) TAM receptors are pleiotropic inhibitors of the innate immune response. Cell 131:1124–1136
-
(2007)
Cell
, vol.131
, pp. 1124-1136
-
-
Rothlin, C.V.1
Ghosh, S.2
Zuniga, E.I.3
Oldstone, M.B.A.4
Lemke, G.5
-
130
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
COI: 1:CAS:528:DC%2BD1MXls1Srsro%3D, PID: 19345186
-
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK (2009) A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137:47–59
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
Gage, F.H.7
Glass, C.K.8
-
131
-
-
33744499683
-
Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
-
COI: 1:CAS:528:DC%2BD28XksleksbY%3D, PID: 16699525
-
Saitoh T, Tun-Kyi A, Ryo A, Yamamoto M, Finn G, Fujita T, Akira S, Yamamoto N, Lu KP, Yamaoka S (2006) Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol 7:598–605
-
(2006)
Nat Immunol
, vol.7
, pp. 598-605
-
-
Saitoh, T.1
Tun-Kyi, A.2
Ryo, A.3
Yamamoto, M.4
Finn, G.5
Fujita, T.6
Akira, S.7
Yamamoto, N.8
Lu, K.P.9
Yamaoka, S.10
-
132
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
COI: 1:CAS:528:DC%2BD3MXnsVCis74%3D, PID: 11547333
-
Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R (2001) Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2:947–950
-
(2001)
Nat Immunol
, vol.2
, pp. 947-950
-
-
Schnare, M.1
Barton, G.M.2
Holt, A.C.3
Takeda, K.4
Akira, S.5
Medzhitov, R.6
-
133
-
-
84964313153
-
Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: new data and a meta-analysis
-
PID: 25492126
-
Senhaji N, Diakite B, Serbati N, Zaid Y, Badre W, Nadifi S (2014) Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: new data and a meta-analysis. BMC Gastroenterol 14:206
-
(2014)
BMC Gastroenterol
, vol.14
, pp. 206
-
-
Senhaji, N.1
Diakite, B.2
Serbati, N.3
Zaid, Y.4
Badre, W.5
Nadifi, S.6
-
134
-
-
36249024235
-
Comparison of expression of heat-shock protein 60, toll-like receptors 2 and 4, and T-cell receptor gammadelta in plaque and guttate psoriasis
-
PID: 18001412
-
Seung NR, Park EJ, Kim CW, Kim KH, Kim KJ, Cho HJ, Park HR (2007) Comparison of expression of heat-shock protein 60, toll-like receptors 2 and 4, and T-cell receptor gammadelta in plaque and guttate psoriasis. J Cutan Pathol 34:903–911
-
(2007)
J Cutan Pathol
, vol.34
, pp. 903-911
-
-
Seung, N.R.1
Park, E.J.2
Kim, C.W.3
Kim, K.H.4
Kim, K.J.5
Cho, H.J.6
Park, H.R.7
-
135
-
-
84883432951
-
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes microbiota dependent resistance to colonization by enteric bacterial pathogens
-
COI: 1:CAS:528:DC%2BC3sXhsVChs7nE, PID: 23950714
-
Sham HP, Yu EYS, Gulen MF, Bhinder G, Stahl M, Chan JM, Brewster L, Morampudi V, Gibson DL, Hughes MR, Mcnagny KM, Li X, Vallance BA (2013) SIGIRR, a negative regulator of TLR/IL-1R signalling promotes microbiota dependent resistance to colonization by enteric bacterial pathogens. PLoS Pathog 9:e1003539
-
(2013)
PLoS Pathog
, vol.9
-
-
Sham, H.P.1
Yu, E.Y.S.2
Gulen, M.F.3
Bhinder, G.4
Stahl, M.5
Chan, J.M.6
Brewster, L.7
Morampudi, V.8
Gibson, D.L.9
Hughes, M.R.10
Mcnagny, K.M.11
Li, X.12
Vallance, B.A.13
-
136
-
-
39449123817
-
Differences in airway cytokine profile in severe asthma compared to moderate asthma
-
COI: 1:CAS:528:DC%2BD1cXjtFemsL8%3D, PID: 18071017
-
Shannon J, Ernst P, Yamauchi Y, Olivenstein R, Lemiere C, Foley S, Cicora L, Ludwig M, Hamid Q, Martin JG (2008) Differences in airway cytokine profile in severe asthma compared to moderate asthma. Chest 133:420–426
-
(2008)
Chest
, vol.133
, pp. 420-426
-
-
Shannon, J.1
Ernst, P.2
Yamauchi, Y.3
Olivenstein, R.4
Lemiere, C.5
Foley, S.6
Cicora, L.7
Ludwig, M.8
Hamid, Q.9
Martin, J.G.10
-
137
-
-
84878141871
-
The TLR4 antagonist Eritoran protects mice from lethal influenza infection
-
COI: 1:CAS:528:DC%2BC3sXmvFyhsLg%3D, PID: 23636320
-
Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, Mcalees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, Vogel SN (2013) The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature 497:498–502
-
(2013)
Nature
, vol.497
, pp. 498-502
-
-
Shirey, K.A.1
Lai, W.2
Scott, A.J.3
Lipsky, M.4
Mistry, P.5
Pletneva, L.M.6
Karp, C.L.7
Mcalees, J.8
Gioannini, T.L.9
Weiss, J.10
Chen, W.H.11
Ernst, R.K.12
Rossignol, D.P.13
Gusovsky, F.14
Blanco, J.C.15
Vogel, S.N.16
-
138
-
-
84959159622
-
Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis
-
COI: 1:CAS:528:DC%2BC28XisFWisLs%3D, PID: 26884587
-
Shmuel-Galia L, Aychek T, Fink A, Porat Z, Zarmi B, Bernshtein B, Brenner O, Jung S, Shai Y (2016) Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis. EMBO J 35:685–698
-
(2016)
EMBO J
, vol.35
, pp. 685-698
-
-
Shmuel-Galia, L.1
Aychek, T.2
Fink, A.3
Porat, Z.4
Zarmi, B.5
Bernshtein, B.6
Brenner, O.7
Jung, S.8
Shai, Y.9
-
139
-
-
84860293001
-
Toll-like receptors are potential therapeutic targets in rheumatoid arthritis
-
PID: 21912729
-
Shotorbani SS, Su ZL, Xu HX (2011) Toll-like receptors are potential therapeutic targets in rheumatoid arthritis. World J Biol Chem 2:167–172
-
(2011)
World J Biol Chem
, vol.2
, pp. 167-172
-
-
Shotorbani, S.S.1
Su, Z.L.2
Xu, H.X.3
-
140
-
-
77954062315
-
Development of TLR7/8 small RNA antagonists
-
PID: 20387163
-
Sioud M (2010) Development of TLR7/8 small RNA antagonists. Methods Mol Biol 629:387–394
-
(2010)
Methods Mol Biol
, vol.629
, pp. 387-394
-
-
Sioud, M.1
-
141
-
-
41449117231
-
Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis
-
PID: 18315430
-
Sorensen LK, Havemose-Poulsen A, Sonder SU, Bendtzen K, Holmstrup P (2008) Blood cell gene expression profiling in subjects with aggressive periodontitis and chronic arthritis. J Periodontol 79:477–485
-
(2008)
J Periodontol
, vol.79
, pp. 477-485
-
-
Sorensen, L.K.1
Havemose-Poulsen, A.2
Sonder, S.U.3
Bendtzen, K.4
Holmstrup, P.5
-
142
-
-
49249138761
-
TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice
-
COI: 1:CAS:528:DC%2BD1cXpsFOjsrw%3D, PID: 18644971
-
Spiller S, Elson G, Ferstl R, Dreher S, Mueller T, Freudenberg M, Daubeuf B, Wagner H, Kirschning CJ (2008) TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice. J Exp Med 205:1747–1754
-
(2008)
J Exp Med
, vol.205
, pp. 1747-1754
-
-
Spiller, S.1
Elson, G.2
Ferstl, R.3
Dreher, S.4
Mueller, T.5
Freudenberg, M.6
Daubeuf, B.7
Wagner, H.8
Kirschning, C.J.9
-
143
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a toll-like receptor 4 and 6 heterodimer
-
COI: 1:CAS:528:DC%2BD1MXhs1SktbvE, PID: 20037584
-
Stewart CR, Stuart LM, Wilkinson K, Van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ (2010) CD36 ligands promote sterile inflammation through assembly of a toll-like receptor 4 and 6 heterodimer. Nat Immunol 11:155–161
-
(2010)
Nat Immunol
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
Van Gils, J.M.4
Deng, J.5
Halle, A.6
Rayner, K.J.7
Boyer, L.8
Zhong, R.9
Frazier, W.A.10
Lacy-Hulbert, A.11
El Khoury, J.12
Golenbock, D.T.13
Moore, K.J.14
-
144
-
-
0036847816
-
Microglia as neuroprotective, immunocompetent cells of the CNS
-
PID: 12379901
-
Streit WJ (2002) Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40:133–139
-
(2002)
Glia
, vol.40
, pp. 133-139
-
-
Streit, W.J.1
-
145
-
-
84893535667
-
Suppression of molecular inflammatory pathways by toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation
-
PID: 24386404
-
Suarez-Farinas M, Arbeit R, Jiang W, Ortenzio FS, Sullivan T, Krueger JG (2013) Suppression of molecular inflammatory pathways by toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation. PLoS One 8:e84634
-
(2013)
PLoS One
, vol.8
-
-
Suarez-Farinas, M.1
Arbeit, R.2
Jiang, W.3
Ortenzio, F.S.4
Sullivan, T.5
Krueger, J.G.6
-
146
-
-
84873814446
-
Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs
-
COI: 1:CAS:528:DC%2BC3sXnsFGnsw%3D%3D, PID: 23257360
-
Subramanian M, Thorp E, Hansson GK, Tabas I (2013) Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs. J Clin Investig 123:179–188
-
(2013)
J Clin Investig
, vol.123
, pp. 179-188
-
-
Subramanian, M.1
Thorp, E.2
Hansson, G.K.3
Tabas, I.4
-
147
-
-
0038781673
-
Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular toll-like receptor 4-MD-2 complex
-
COI: 1:CAS:528:DC%2BD3sXkt1Ojsrg%3D, PID: 12761135
-
Suzuki M, Hisamatsu T, Podolsky DK (2003) Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular toll-like receptor 4-MD-2 complex. Infect Immun 71:3503–3511
-
(2003)
Infect Immun
, vol.71
, pp. 3503-3511
-
-
Suzuki, M.1
Hisamatsu, T.2
Podolsky, D.K.3
-
148
-
-
84919657823
-
Expression and implication of toll-like receptors TLR2, TLR4 and TLR9 in colonic mucosa of patients with ulcerative colitis
-
COI: 1:CAS:528:DC%2BC2cXhvVequrjI, PID: 25318894
-
Tan Y, Zou KF, Qian W, Chen S, Hou XH (2014) Expression and implication of toll-like receptors TLR2, TLR4 and TLR9 in colonic mucosa of patients with ulcerative colitis. J Huazhong Univ Sci Technol Med Sci 34:785–790
-
(2014)
J Huazhong Univ Sci Technol Med Sci
, vol.34
, pp. 785-790
-
-
Tan, Y.1
Zou, K.F.2
Qian, W.3
Chen, S.4
Hou, X.H.5
-
149
-
-
58149263333
-
Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions
-
COI: 1:CAS:528:DC%2BD1MXivVGlu7k%3D, PID: 19055649
-
Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T (2009) Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions. Clin Exp Allergy 39:89–100
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 89-100
-
-
Tanaka, J.1
Watanabe, N.2
Kido, M.3
Saga, K.4
Akamatsu, T.5
Nishio, A.6
Chiba, T.7
-
150
-
-
49349097868
-
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
-
COI: 1:CAS:528:DC%2BD1cXhtVSgurnP, PID: 18586243
-
Tang SC, Lathia JD, Selvaraj PK, Jo DG, Mughal MR, Cheng A, Siler DA, Markesbery WR, Arumugam TV, Mattson MP (2008) Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol 213:114–121
-
(2008)
Exp Neurol
, vol.213
, pp. 114-121
-
-
Tang, S.C.1
Lathia, J.D.2
Selvaraj, P.K.3
Jo, D.G.4
Mughal, M.R.5
Cheng, A.6
Siler, D.A.7
Markesbery, W.R.8
Arumugam, T.V.9
Mattson, M.P.10
-
151
-
-
0037386810
-
High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine
-
COI: 1:CAS:528:DC%2BD3sXjtlKnsrk%3D, PID: 12687539
-
Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, Inoue K, Yamada S, Ijiri K, Matsunaga S, Nakajima T, Komiya S, Maruyama I (2003) High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 48:971–981
-
(2003)
Arthritis Rheum
, vol.48
, pp. 971-981
-
-
Taniguchi, N.1
Kawahara, K.2
Yone, K.3
Hashiguchi, T.4
Yamakuchi, M.5
Goto, M.6
Inoue, K.7
Yamada, S.8
Ijiri, K.9
Matsunaga, S.10
Nakajima, T.11
Komiya, S.12
Maruyama, I.13
-
152
-
-
4344688090
-
Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma
-
COI: 1:CAS:528:DC%2BD2cXlvVals7g%3D, PID: 15266299
-
Tantisira K, Klimecki WT, Lazarus R, Palmer LJ, Raby BA, Kwiatkowski DJ, Silverman E, Vercelli D, Martinez FD, Weiss ST (2004) Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma. Genes Immun 5:343–346
-
(2004)
Genes Immun
, vol.5
, pp. 343-346
-
-
Tantisira, K.1
Klimecki, W.T.2
Lazarus, R.3
Palmer, L.J.4
Raby, B.A.5
Kwiatkowski, D.J.6
Silverman, E.7
Vercelli, D.8
Martinez, F.D.9
Weiss, S.T.10
-
153
-
-
0037033364
-
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4
-
COI: 1:CAS:528:DC%2BD38XjslOjtw%3D%3D, PID: 11781369
-
Termeer C, Benedix F, Sleeman J, Fieber C, Voith U, Ahrens T, Miyake K, Freudenberg M, Galanos C, Simon JC (2002) Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 195:99–111
-
(2002)
J Exp Med
, vol.195
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
Fieber, C.4
Voith, U.5
Ahrens, T.6
Miyake, K.7
Freudenberg, M.8
Galanos, C.9
Simon, J.C.10
-
154
-
-
47249128991
-
Th17 cells in human disease
-
COI: 1:CAS:528:DC%2BD1cXptlGls7s%3D, PID: 18613831
-
Tesmer LA, Lundy SK, Sarkar S, Fox DA (2008) Th17 cells in human disease. Immunol Rev 223:87–113
-
(2008)
Immunol Rev
, vol.223
, pp. 87-113
-
-
Tesmer, L.A.1
Lundy, S.K.2
Sarkar, S.3
Fox, D.A.4
-
155
-
-
84895524861
-
Emerging role of endosomal toll-like receptors in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2MXht1enurjL, PID: 24474949
-
Thwaites R, Chamberlain G, Sacre S (2014) Emerging role of endosomal toll-like receptors in rheumatoid arthritis. Front Immunol 5:1
-
(2014)
Front Immunol
, vol.5
, pp. 1
-
-
Thwaites, R.1
Chamberlain, G.2
Sacre, S.3
-
156
-
-
72449141468
-
Differential expression of toll-like receptor mRNA in selected tissues of goat (Capra hircus)
-
COI: 1:CAS:528:DC%2BD1MXhs1Wns7vM, PID: 19748133
-
Tirumurugaan KG, Dhanasekaran S, Raj GD, Raja A, Kumanan K, Ramaswamy V (2010) Differential expression of toll-like receptor mRNA in selected tissues of goat (Capra hircus). Vet Immunol Immunopathol 133:296–301
-
(2010)
Vet Immunol Immunopathol
, vol.133
, pp. 296-301
-
-
Tirumurugaan, K.G.1
Dhanasekaran, S.2
Raj, G.D.3
Raja, A.4
Kumanan, K.5
Ramaswamy, V.6
-
157
-
-
59049100417
-
Allergenicity resulting from functional mimicry of a toll-like receptor complex protein
-
COI: 1:CAS:528:DC%2BD1MXhtFOmtr8%3D, PID: 19060881
-
Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R, Thorne PS, Wills-Karp M, Gioannini TL, Weiss JP, Karp CL (2009) Allergenicity resulting from functional mimicry of a toll-like receptor complex protein. Nature 457:585–588
-
(2009)
Nature
, vol.457
, pp. 585-588
-
-
Trompette, A.1
Divanovic, S.2
Visintin, A.3
Blanchard, C.4
Hegde, R.S.5
Madan, R.6
Thorne, P.S.7
Wills-Karp, M.8
Gioannini, T.L.9
Weiss, J.P.10
Karp, C.L.11
-
158
-
-
34247239745
-
Various human epithelial cells express functional toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines
-
COI: 1:CAS:528:DC%2BD2sXksVejurk%3D, PID: 17403538
-
Uehara A, Fujimoto Y, Fukase K, Takada H (2007) Various human epithelial cells express functional toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines. Mol Immunol 44:3100–3111
-
(2007)
Mol Immunol
, vol.44
, pp. 3100-3111
-
-
Uehara, A.1
Fujimoto, Y.2
Fukase, K.3
Takada, H.4
-
159
-
-
67049095880
-
A novel toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis
-
COI: 1:CAS:528:DC%2BD1MXnsVCltbY%3D, PID: 19359427
-
Ungaro R, Fukata M, Hsu D, Hernandez Y, Breglio K, Chen A, Xu R, Sotolongo J, Espana C, Zaias J, Elson G, Mayer L, Kosco-Vilbois M, Abreu MT (2009) A novel toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol 296:G1167–G1179
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
, pp. G1167-G1179
-
-
Ungaro, R.1
Fukata, M.2
Hsu, D.3
Hernandez, Y.4
Breglio, K.5
Chen, A.6
Xu, R.7
Sotolongo, J.8
Espana, C.9
Zaias, J.10
Elson, G.11
Mayer, L.12
Kosco-Vilbois, M.13
Abreu, M.T.14
-
160
-
-
66949162673
-
Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
-
PID: 19380832
-
Van Der Fits L, Mourits S, Voerman JS, Kant M, Boon L, Laman JD, Cornelissen F, Mus AM, Florencia E, Prens EP, Lubberts E (2009) Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol 182:5836–5845
-
(2009)
J Immunol
, vol.182
, pp. 5836-5845
-
-
Van Der Fits, L.1
Mourits, S.2
Voerman, J.S.3
Kant, M.4
Boon, L.5
Laman, J.D.6
Cornelissen, F.7
Mus, A.M.8
Florencia, E.9
Prens, E.P.10
Lubberts, E.11
-
161
-
-
34547638394
-
Activation of toll-like receptor 3 protects against DSS-induced acute colitis
-
PID: 17393379
-
Vijay-Kumar M, Wu H, Aitken J, Kolachala VL, Neish AS, Sitaraman SV, Gewirtz AT (2007) Activation of toll-like receptor 3 protects against DSS-induced acute colitis. Inflamm Bowel Dis 13:856–864
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 856-864
-
-
Vijay-Kumar, M.1
Wu, H.2
Aitken, J.3
Kolachala, V.L.4
Neish, A.S.5
Sitaraman, S.V.6
Gewirtz, A.T.7
-
162
-
-
57349084248
-
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice
-
COI: 1:CAS:528:DC%2BD1cXhsFSjsr3E, PID: 18787221
-
Wakashin H, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N, Saito Y, Hatano M, Tokuhisa T, Iwakura Y, Puccetti P, Iwamoto I, Nakajima H (2008) IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med 178:1023–1032
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1023-1032
-
-
Wakashin, H.1
Hirose, K.2
Maezawa, Y.3
Kagami, S.4
Suto, A.5
Watanabe, N.6
Saito, Y.7
Hatano, M.8
Tokuhisa, T.9
Iwakura, Y.10
Puccetti, P.11
Iwamoto, I.12
Nakajima, H.13
-
163
-
-
0042733592
-
SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling
-
COI: 1:CAS:528:DC%2BD3sXms12gtLw%3D, PID: 12925853
-
Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, Towne J, Sims JE, Stark GR, Li X (2003) SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 4:920–927
-
(2003)
Nat Immunol
, vol.4
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
Qian, Y.4
Naramura, M.5
Tian, L.6
Towne, J.7
Sims, J.E.8
Stark, G.R.9
Li, X.10
-
164
-
-
35848963223
-
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2sXht1Cku7zP, PID: 17982277
-
Walter S, Letiembre M, Liu Y, Heine H, Penke B, Hao W, Bode B, Manietta N, Walter J, Schulz-Schuffer W, Fassbender K (2007) Role of the toll-like receptor 4 in neuroinflammation in Alzheimer’s disease. Cell Physiol Biochem 20:947–956
-
(2007)
Cell Physiol Biochem
, vol.20
, pp. 947-956
-
-
Walter, S.1
Letiembre, M.2
Liu, Y.3
Heine, H.4
Penke, B.5
Hao, W.6
Bode, B.7
Manietta, N.8
Walter, J.9
Schulz-Schuffer, W.10
Fassbender, K.11
-
165
-
-
84875878203
-
Aldara activates TLR7-independent immune defence
-
PID: 23463003
-
Walter A, Schafer M, Cecconi V, Matter C, Urosevic-Maiwald M, Belloni B, Schonewolf N, Dummer R, Bloch W, Werner S, Beer HD, Knuth A, Van Den Broek M (2013) Aldara activates TLR7-independent immune defence. Nat Commun 4:1560
-
(2013)
Nat Commun
, vol.4
, pp. 1560
-
-
Walter, A.1
Schafer, M.2
Cecconi, V.3
Matter, C.4
Urosevic-Maiwald, M.5
Belloni, B.6
Schonewolf, N.7
Dummer, R.8
Bloch, W.9
Werner, S.10
Beer, H.D.11
Knuth, A.12
Van Den Broek, M.13
-
166
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates toll-like receptor-interleukin 1 receptor signaling
-
COI: 1:CAS:528:DC%2BD28Xlt1ersw%3D%3D, PID: 16378096
-
Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G (2006) Association of beta-arrestin and TRAF6 negatively regulates toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 7:139–147
-
(2006)
Nat Immunol
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
Wu, Y.4
Zhao, X.5
Pei, G.6
-
167
-
-
4444253690
-
NOD2 is a negative regulator of toll-like receptor 2-mediated T helper type 1 responses
-
COI: 1:CAS:528:DC%2BD2cXmtVCgtL8%3D, PID: 15220916
-
Watanabe T, Kitani A, Murray PJ, Strober W (2004) NOD2 is a negative regulator of toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5:800–808
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
168
-
-
34547771610
-
Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk
-
COI: 1:CAS:528:DC%2BD2sXptVyjsb4%3D, PID: 17646407
-
Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D (2007) Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med 204:1911–1922
-
(2007)
J Exp Med
, vol.204
, pp. 1911-1922
-
-
Wu, H.J.1
Sawaya, H.2
Binstadt, B.3
Brickelmaier, M.4
Blasius, A.5
Gorelik, L.6
Mahmood, U.7
Weissleder, R.8
Carulli, J.9
Benoist, C.10
Mathis, D.11
-
169
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
COI: 1:CAS:528:DC%2BD2sXotFajurs%3D, PID: 17653185
-
Xavier RJ, Podolsky DK (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448:427–434
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
170
-
-
84868316949
-
R753Q polymorphism inhibits toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88
-
COI: 1:CAS:528:DC%2BC38Xhs1Wjtb%2FJ, PID: 22992740
-
Xiong Y, Song C, Snyder GA, Sundberg EJ, Medvedev AE (2012) R753Q polymorphism inhibits toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88. J Biol Chem 287:38327–38337
-
(2012)
J Biol Chem
, vol.287
, pp. 38327-38337
-
-
Xiong, Y.1
Song, C.2
Snyder, G.A.3
Sundberg, E.J.4
Medvedev, A.E.5
-
171
-
-
28544447821
-
Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl)cyclohex-1-ene-1-carboxylate
-
COI: 1:CAS:528:DC%2BD2MXhtFahsbfE, PID: 16279805
-
Yamada M, Ichikawa T, Ii M, Sunamoto M, Itoh K, Tamura N, Kitazaki T (2005) Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl)cyclohex-1-ene-1-carboxylate. J Med Chem 48:7457–7467
-
(2005)
J Med Chem
, vol.48
, pp. 7457-7467
-
-
Yamada, M.1
Ichikawa, T.2
Ii, M.3
Sunamoto, M.4
Itoh, K.5
Tamura, N.6
Kitazaki, T.7
-
172
-
-
33846922783
-
Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs
-
COI: 1:CAS:528:DC%2BD2sXht1Cgu7s%3D, PID: 17277125
-
Yarilina A, Dicarlo E, Ivashkiv LB (2007) Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs. J Immunol 178:2204–2211
-
(2007)
J Immunol
, vol.178
, pp. 2204-2211
-
-
Yarilina, A.1
Dicarlo, E.2
Ivashkiv, L.B.3
-
173
-
-
84905641569
-
Multiple roles of toll-like receptor 4 in colorectal cancer
-
PID: 25076949
-
Yesudhas D, Gosu V, Anwar MA, Choi S (2014) Multiple roles of toll-like receptor 4 in colorectal cancer. Front Immunol 5:334
-
(2014)
Front Immunol
, vol.5
, pp. 334
-
-
Yesudhas, D.1
Gosu, V.2
Anwar, M.A.3
Choi, S.4
-
174
-
-
84857335818
-
Structural basis of TLR5-flagellin recognition and signaling
-
COI: 1:CAS:528:DC%2BC38XitFGqur4%3D, PID: 22344444
-
Yoon SI, Kurnasov O, Natarajan V, Hong M, Gudkov AV, Osterman AL, Wilson IA (2012) Structural basis of TLR5-flagellin recognition and signaling. Science 335:859–864
-
(2012)
Science
, vol.335
, pp. 859-864
-
-
Yoon, S.I.1
Kurnasov, O.2
Natarajan, V.3
Hong, M.4
Gudkov, A.V.5
Osterman, A.L.6
Wilson, I.A.7
-
175
-
-
78650130030
-
The ubiquitin E3 ligase RAUL negatively regulates type I interferon through ubiquitination of the transcription factors IRF7 and IRF3
-
COI: 1:CAS:528:DC%2BC3cXhsFyisL3J, PID: 21167755
-
Yu Y, Hayward GS (2010) The ubiquitin E3 ligase RAUL negatively regulates type I interferon through ubiquitination of the transcription factors IRF7 and IRF3. Immunity 33:863–877
-
(2010)
Immunity
, vol.33
, pp. 863-877
-
-
Yu, Y.1
Hayward, G.S.2
-
176
-
-
70349838270
-
Cultured human melanocytes express functional toll-like receptors 2–4, 7 and 9
-
COI: 1:CAS:528:DC%2BD1MXht1Wrtb7L, PID: 19740627
-
Yu N, Zhang S, Zuo F, Kang K, Guan M, Xiang L (2009) Cultured human melanocytes express functional toll-like receptors 2–4, 7 and 9. J Dermatol Sci 56:113–120
-
(2009)
J Dermatol Sci
, vol.56
, pp. 113-120
-
-
Yu, N.1
Zhang, S.2
Zuo, F.3
Kang, K.4
Guan, M.5
Xiang, L.6
-
177
-
-
0037080024
-
Tissue expression of human toll-like receptors and differential regulation of toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
-
COI: 1:CAS:528:DC%2BD38XksFWntg%3D%3D, PID: 11777946
-
Zarember KA, Godowski PJ (2002) Tissue expression of human toll-like receptors and differential regulation of toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 168:554–561
-
(2002)
J Immunol
, vol.168
, pp. 554-561
-
-
Zarember, K.A.1
Godowski, P.J.2
-
178
-
-
84949568215
-
Molecular regulation of toll-like receptors in asthma and COPD
-
PID: 26617525
-
Zuo L, Lucas K, Fortuna CA, Chuang CC, Best TM (2015) Molecular regulation of toll-like receptors in asthma and COPD. Front Physiol 6:312
-
(2015)
Front Physiol
, vol.6
, pp. 312
-
-
Zuo, L.1
Lucas, K.2
Fortuna, C.A.3
Chuang, C.C.4
Best, T.M.5
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