-
2
-
-
0034665374
-
The membrane form of the type II IL-1 receptor accounts for inhibitory function
-
Neumann, D., Kollewe, C., Martin, M.U. & Boraschi, D. The membrane form of the type II IL-1 receptor accounts for inhibitory function. J. Immunol. 165, 3350-3357 (2000).
-
(2000)
J. Immunol.
, vol.165
, pp. 3350-3357
-
-
Neumann, D.1
Kollewe, C.2
Martin, M.U.3
Boraschi, D.4
-
3
-
-
0033952638
-
The role of IL-18 in innate immunity
-
Akira, S. The role of IL-18 in innate immunity. Curr. Opin. Immunol. 12, 59-63 (2000).
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 59-63
-
-
Akira, S.1
-
4
-
-
0034689033
-
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
-
Townsend, M.J., Fallon, P.G., Matthews, D.J., John, H.E. & McKenzie, A.N. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J. Exp. Med. 191, 1069-1076 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1069-1076
-
-
Townsend, M.J.1
Fallon, P.G.2
Matthews, D.J.3
John, H.E.4
McKenzie, A.N.5
-
5
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou, L., Holt, A.C., Medzhitov, R. & Flavell, R.A. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413, 732-738 (2001).
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
6
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi, O. et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451 (1999).
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
-
7
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky, A. et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. USA 97, 13766-13771 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
-
8
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H. et al. A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (2000).
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
-
9
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F. et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103 (2001).
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
-
10
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino, K. et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162, 3749-3752 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
-
11
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
2003 re3
-
Dunne, A. & O'Neill, L.A. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci. STKE 2003, re3(2003).
-
(2003)
Sci. STKE
-
-
Dunne, A.1
O'Neill, L.A.2
-
12
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio, M., Ni, J., Feng, P. & Dixit, V.M. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278, 1612-1615 (1997).
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
13
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche, H., Henzel, W.J., Shillinglaw, W., Li, S. & Cao, Z. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7, 837-847 (1997).
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
14
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
Burns, K. et al. MyD88, an adapter protein involved in interleukin-1 signaling. J. Biol. Chem. 273, 12203-12209 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
-
15
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao, Z., Henzel, W.J. & Gao, X. IRAK: a kinase associated with the interleukin-1 receptor. Science 271, 1128-1131 (1996).
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
16
-
-
0037117543
-
IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
-
Li, S., Strelow, A., Fontana, E.J. & Wesche, H. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 99, 5567-5572 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5567-5572
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
Wesche, H.4
-
17
-
-
0037799886
-
Pellino 1 is required for Interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex
-
Jiang, Z. et al. Pellino 1 is required for Interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex. J. Biol. Chem. 278, 10952-10956 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10952-10956
-
-
Jiang, Z.1
-
18
-
-
0036788753
-
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol
-
Jiang, Z., Ninomiya-Tsuji, J., Qian, Y., Matsumoto, K. & Li, X. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell. Biol. 22, 7158-7167 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7158-7167
-
-
Jiang, Z.1
Ninomiya-Tsuji, J.2
Qian, Y.3
Matsumoto, K.4
Li, X.5
-
19
-
-
0035099717
-
Interleulkin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway
-
Takaesu, G. et al. Interleulkin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol. Cell. Biol. 21, 2475-2484 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2475-2484
-
-
Takaesu, G.1
-
20
-
-
0031586174
-
Identification and characterization of an IκB kinase
-
Regnier, C.H. et al. Identification and characterization of an IκB kinase. Cell 90, 373-383 (1997).
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
-
21
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F. et al. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 278, 860-866 (1997 ).
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
-
22
-
-
0038714270
-
Poly I:C-induced TLR3-mediated activation of NF-κB and MAP kinases is through an IRAK-independent pathway employing signaling components TLR3-TRAF6-TAK1-TAB2-PKR
-
Jiang, Z. et al. Poly I:C-induced TLR3-mediated activation of NF-κB and MAP kinases is through an IRAK-independent pathway employing signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J. Biol. Chem. 278, 16713-16719 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16713-16719
-
-
Jiang, Z.1
-
23
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
-
Yamamoto, M. et al. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J. Immunol. 169, 6668-6672 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
-
24
-
-
0037322295
-
Toll signaling: The TIReless quest for specificity
-
Imler, J.L. & Hoffmann, J.A. Toll signaling: the TIReless quest for specificity. Nat. Immunol. 4, 105-106 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 105-106
-
-
Imler, J.L.1
Hoffmann, J.A.2
-
25
-
-
0033810383
-
Pathophysiologic basis of sepsis: Considerations for future strategies of intervention
-
Glauser, M.P. Pathophysiologic basis of sepsis: considerations for future strategies of intervention. Crit. Care. Med. 28, S4-8 (2000).
-
(2000)
Crit. Care. Med.
, vol.28
-
-
Glauser, M.P.1
-
26
-
-
0036457057
-
Inflammatory bowel disease: New insights into pathogenesis and treatment
-
Ardizzone, S. & Porro, G.B. Inflammatory bowel disease: new insights into pathogenesis and treatment. J. Intern. Med. 252, 475-496 (2002).
-
(2002)
J. Intern. Med.
, vol.252
, pp. 475-496
-
-
Ardizzone, S.1
Porro, G.B.2
-
27
-
-
0036730319
-
The pathogenesis of rheumatoid arthritis: Pivotal cytokines involved in bone degradation and inflammation
-
Bingham, C.O., III. The pathogenesis of rheumatoid arthritis: pivotal cytokines involved in bone degradation and inflammation. J. Rheumatol. Suppl. 65, 3-9 (2002).
-
(2002)
J. Rheumatol. Suppl.
, vol.65
, pp. 3-9
-
-
Bingham C.O. III1
-
28
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi, K. et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110, 191-202 (2002).
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
-
29
-
-
0037454946
-
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
-
Burns, K. et al. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197, 263-268 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 263-268
-
-
Burns, K.1
-
30
-
-
0036006290
-
Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88
-
Janssens, S., Burns, K., Tschopp, J. & Beyaert, R. Regulation of interleukin-1- and lipopolysaccharide-induced NF-κB activation by alternative splicing of MyD88. Curr. Biol. 12, 467-471 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 467-471
-
-
Janssens, S.1
Burns, K.2
Tschopp, J.3
Beyaert, R.4
-
31
-
-
0033151633
-
Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
-
Thomassen, E., Renshaw, B.R. & Sims, J.E. Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. Cytokine 11, 389-399 (1999).
-
(1999)
Cytokine
, vol.11
, pp. 389-399
-
-
Thomassen, E.1
Renshaw, B.R.2
Sims, J.E.3
-
32
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., Xiong, J., Takeuchi, M., Kurama, T. & Goeddel, D.V. TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446 (1996).
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
33
-
-
0032190902
-
Divergent effects of LPS on expression of IL-1 receptor family members in mononuclear phagocytes in vitro and in vivo
-
Saccani, S., Polentarutti, N., Penton-Rol, G., Sims, J.E. & Mantovani, A. Divergent effects of LPS on expression of IL-1 receptor family members in mononuclear phagocytes in vitro and in vivo. Cytokine 10, 773-780 (1998).
-
(1998)
Cytokine
, vol.10
, pp. 773-780
-
-
Saccani, S.1
Polentarutti, N.2
Penton-Rol, G.3
Sims, J.E.4
Mantovani, A.5
-
34
-
-
0033105652
-
Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition of mRNA expression, of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction of incompletely spliced transcripts
-
Penton-Rol, G. et al. Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition of mRNA expression, of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction of incompletely spliced transcripts. J. Immunol. 162, 2931-2938 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 2931-2938
-
-
Penton-Rol, G.1
-
35
-
-
0024317761
-
The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms
-
Mosley, B. et al. The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell 59, 335-348 (1989).
-
(1989)
Cell
, vol.59
, pp. 335-348
-
-
Mosley, B.1
-
36
-
-
0028987479
-
Stimulation of NF-κB-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus
-
Mitchell, T. & Sugden, B. Stimulation of NF-κB-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus. J. Virol. 69, 2968-2976 (1995).
-
(1995)
J. Virol.
, vol.69
, pp. 2968-2976
-
-
Mitchell, T.1
Sugden, B.2
|