Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling

Journal of Immunology

Volumn 182, Issue 8, 2009, Pages 4965-4973

  Huang, Qi Quan ^a   Sobkoviak, Rudina ^a   Jockheck Clark, Angela R ^d   Shi, Bo ^a   Mandelin II, Arthur M ^a   Tak, Paul Peter ^b   Haines III, G Kennith ^c   Nicchitta, Christopher V ^d   Pope, Richard M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 96; INTERLEUKIN 8; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; SARCOMA GLYCOPROTEIN GP96 REJECTION ANTIGENS; TLR4 PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTHRITIS; ARTICLE; CELL ACTIVATION; CELL SURFACE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; MACROPHAGE; MONOCYTE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; SYNOVIUM; ANIMAL; CELL FREE SYSTEM; CELL LINE; DOG; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, NEOPLASM; ARTHRITIS, RHEUMATOID; CELL LINE; CELL-FREE SYSTEM; DOGS; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 65249190995     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0801563     Document Type: Article

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