-
1
-
-
3142724031
-
Toll-like receptor signalling
-
doi: 10.1038/nri1391
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol (2004) 4(7):499-511. doi: 10.1038/nri1391
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.7
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
2
-
-
84865571191
-
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
-
doi:10.1126/science.1220363
-
Oldenburg M, Kruger A, Ferstl R, Kaufmann A, Nees G, Sigmund A, et al. TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science (2012) 337(6098):1111-5. doi:10.1126/science.1220363
-
(2012)
Science
, vol.337
, Issue.6098
, pp. 1111-1115
-
-
Oldenburg, M.1
Kruger, A.2
Ferstl, R.3
Kaufmann, A.4
Nees, G.5
Sigmund, A.6
-
3
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on toll-like receptors
-
doi:10.1038/ni.1863
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on toll-like receptors. Nat Immunol (2010) 11(5):373-84. doi:10.1038/ni.1863
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
4
-
-
0034650420
-
Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
-
doi:10.4049/jimmunol.164.2.554
-
Takeuchi O, Kaufmann A, Grote K, Kawai T, Hoshino K, Morr M, et al. Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J Immunol (2000) 164(2):554-7. doi:10.4049/jimmunol.164.2.554
-
(2000)
J Immunol
, vol.164
, Issue.2
, pp. 554-557
-
-
Takeuchi, O.1
Kaufmann, A.2
Grote, K.3
Kawai, T.4
Hoshino, K.5
Morr, M.6
-
5
-
-
0036644042
-
Cutting edge: role of toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
doi:10.4049/jimmunol.169.1.10
-
Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, et al. Cutting edge: role of toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol (2002) 169(1):10-4. doi:10.4049/jimmunol.169.1.10
-
(2002)
J Immunol
, vol.169
, Issue.1
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
-
6
-
-
0034922923
-
Discrimination of bacterial lipoproteins by toll-like receptor 6
-
doi:10.1093/intimm/13.7.933
-
Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, et al. Discrimination of bacterial lipoproteins by toll-like receptor 6. Int Immunol (2001) 13(7):933-40. doi:10.1093/intimm/13.7.933
-
(2001)
Int Immunol
, vol.13
, Issue.7
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
-
7
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by toll-like receptor 3
-
doi:10.1038/35099560
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by toll-like receptor 3. Nature (2001) 413(6857):732-8. doi:10.1038/35099560
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
8
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
doi:10.1126/science.282.5396.2085
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 282(5396):2085-8. doi:10.1126/science.282.5396.2085
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
-
9
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by toll-like receptor 5
-
doi:10.1038/35074106
-
Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, et al. The innate immune response to bacterial flagellin is mediated by toll-like receptor 5. Nature (2001) 410(6832):1099-103. doi:10.1038/35074106
-
(2001)
Nature
, vol.410
, Issue.6832
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
-
10
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
doi:10.1126/science.1093616
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis E, Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science (2004) 303(5663):1529-31. doi:10.1126/science.1093616
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis, E.5
Sousa, C.6
-
11
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
doi:10.1126/science.1093620
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science (2004) 303(5663):1526-9. doi:10.1126/science.1093620
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
-
12
-
-
0034619794
-
A toll-like receptor recognizes bacterial DNA
-
doi:10.1038/35047123
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, et al. A toll-like receptor recognizes bacterial DNA. Nature (2000) 408(6813):740-5. doi:10.1038/35047123
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
-
13
-
-
3142683548
-
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function
-
doi:10.1016/j.immuni.2004.06.007
-
Krug A, French AR, Barchet W, Fischer JA, Dzionek A, Pingel JT, et al. TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. Immunity (2004) 21(1):107-19. doi:10.1016/j.immuni.2004.06.007
-
(2004)
Immunity
, vol.21
, Issue.1
, pp. 107-119
-
-
Krug, A.1
French, A.R.2
Barchet, W.3
Fischer, J.A.4
Dzionek, A.5
Pingel, J.T.6
-
14
-
-
84870189452
-
Therapeutic applications of nucleic acids and their analogues in toll-like receptor signaling
-
doi:10.3390/molecules171113503
-
Gosu V, Basith S, Kwon OP, Choi S. Therapeutic applications of nucleic acids and their analogues in toll-like receptor signaling. Molecules (2012) 17(11):13503-29. doi:10.3390/molecules171113503
-
(2012)
Molecules
, vol.17
, Issue.11
, pp. 13503-13529
-
-
Gosu, V.1
Basith, S.2
Kwon, O.P.3
Choi, S.4
-
15
-
-
77249150015
-
The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis
-
doi:10.1038/mi.2009.124
-
Lavelle EC, Murphy C, O'Neill LA, Creagh EM. The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis. Mucosal Immunol (2010) 3(1):17-28. doi:10.1038/mi.2009.124
-
(2010)
Mucosal Immunol
, vol.3
, Issue.1
, pp. 17-28
-
-
Lavelle, E.C.1
Murphy, C.2
O'Neill, L.A.3
Creagh, E.M.4
-
16
-
-
44649161808
-
Role of toll-like receptors in tissue repair and tumorigenesis
-
doi:10.1134/S0006297908050088
-
Rakoff-Nahoum S, Medzhitov R. Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc) (2008) 73(5):555-61. doi:10.1134/S0006297908050088
-
(2008)
Biochemistry (Mosc)
, vol.73
, Issue.5
, pp. 555-561
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
17
-
-
78650494568
-
The application of toll like receptors for cancer therapy
-
doi:10.7150/ijbs.6.675
-
So EY, Ouchi T. The application of toll like receptors for cancer therapy. Int J Biol Sci (2010) 6(7):675-81. doi:10.7150/ijbs.6.675
-
(2010)
Int J Biol Sci
, vol.6
, Issue.7
, pp. 675-681
-
-
So, E.Y.1
Ouchi, T.2
-
18
-
-
79959773879
-
Toll-like receptors as targets for immune disorders
-
doi:10.1016/j.tips.2011.03.008
-
Keogh B, Parker AE. Toll-like receptors as targets for immune disorders. Trends Pharmacol Sci (2011) 32(7):435-42. doi:10.1016/j.tips.2011.03.008
-
(2011)
Trends Pharmacol Sci
, vol.32
, Issue.7
, pp. 435-442
-
-
Keogh, B.1
Parker, A.E.2
-
19
-
-
79953020324
-
A novel toll-like receptor that recognizes vesicular stomatitis virus
-
doi:10.1074/jbc.M110.159590
-
Shi Z, Cai Z, Sanchez A, Zhang T, Wen S, Wang J, et al. A novel toll-like receptor that recognizes vesicular stomatitis virus. J Biol Chem (2011) 286(6):4517-24. doi:10.1074/jbc.M110.159590
-
(2011)
J Biol Chem
, vol.286
, Issue.6
, pp. 4517-4524
-
-
Shi, Z.1
Cai, Z.2
Sanchez, A.3
Zhang, T.4
Wen, S.5
Wang, J.6
-
20
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
doi:10.1038/nature04870
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature (2006) 441(7092):431-6. doi:10.1038/nature04870
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
21
-
-
25844459154
-
NF-kappaB: linking inflammation and immunity to cancer development and progression
-
doi:10.1038/nri1703
-
Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol (2005) 5(10):749-59. doi:10.1038/nri1703
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.10
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
22
-
-
39449127013
-
Expression of toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis
-
doi:10.1369/jhc.7A7303.2007
-
Frolova L, Drastich P, Rossmann P, Klimesova K, Tlaskalova-Hogenova H. Expression of toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. J Histochem Cytochem (2008) 56(3):267-74. doi:10.1369/jhc.7A7303.2007
-
(2008)
J Histochem Cytochem
, vol.56
, Issue.3
, pp. 267-274
-
-
Frolova, L.1
Drastich, P.2
Rossmann, P.3
Klimesova, K.4
Tlaskalova-Hogenova, H.5
-
23
-
-
84874747481
-
Cancer screening in the United States, 2013
-
doi:10.3322/caac.21174
-
Smith RA, Brooks D, Cokkinides V, Saslow D, Brawley OW. Cancer screening in the United States, 2013. CA Cancer J Clin (2013) 63(2):87-105. doi:10.3322/caac.21174
-
(2013)
CA Cancer J Clin
, vol.63
, Issue.2
, pp. 87-105
-
-
Smith, R.A.1
Brooks, D.2
Cokkinides, V.3
Saslow, D.4
Brawley, O.W.5
-
24
-
-
67349245787
-
New insights into the aetiology of colorectal cancer from genome-wide association studies
-
doi:10.1038/nrg2574
-
Tenesa A, Dunlop MG. New insights into the aetiology of colorectal cancer from genome-wide association studies. Nat Rev Genet (2009) 10(6):353-8. doi:10.1038/nrg2574
-
(2009)
Nat Rev Genet
, vol.10
, Issue.6
, pp. 353-358
-
-
Tenesa, A.1
Dunlop, M.G.2
-
25
-
-
77951635438
-
Inflammation and colon cancer.
-
2101-14.e5. doi:10.1053/j.gastro.2010.01.058
-
Terzic J, Grivennikov S, Karin E, Karin M. Inflammation and colon cancer. Gastroenterology (2010) 138(6): 2101-14.e5. doi:10.1053/j.gastro.2010.01.058
-
(2010)
Gastroenterology
, vol.138
, Issue.6
-
-
Terzic, J.1
Grivennikov, S.2
Karin, E.3
Karin, M.4
-
26
-
-
79957542899
-
Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review.
-
doi:10.1186/1471-230X-11-65
-
Adelstein BA, Macaskill P, Chan SF, Katelaris PH, Irwig L. Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review. BMC Gastroenterol (2011) 11:65. doi:10.1186/1471-230X-11-65
-
(2011)
BMC Gastroenterol
, vol.11
, pp. 65
-
-
Adelstein, B.A.1
Macaskill, P.2
Chan, S.F.3
Katelaris, P.H.4
Irwig, L.5
-
27
-
-
0037654784
-
Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529
-
doi:10.1586/14760584.2.2.219
-
Evans JT, Cluff CW, Johnson DA, Lacy MJ, Persing DH, Baldridge JR. Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529. Expert Rev Vaccines (2003) 2(2):219-29. doi:10.1586/14760584.2.2.219
-
(2003)
Expert Rev Vaccines
, vol.2
, Issue.2
, pp. 219-229
-
-
Evans, J.T.1
Cluff, C.W.2
Johnson, D.A.3
Lacy, M.J.4
Persing, D.H.5
Baldridge, J.R.6
-
28
-
-
77949940198
-
Intracellular toll-like receptors
-
doi:10.1016/j.immuni.2010.03.012
-
Blasius AL, Beutler B. Intracellular toll-like receptors. Immunity (2010) 32(3):305-15. doi:10.1016/j.immuni.2010.03.012
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 305-315
-
-
Blasius, A.L.1
Beutler, B.2
-
29
-
-
84869108498
-
Molecular evolution and structural features of IRAK family members.
-
doi:10.1371/journal.pone.0049771
-
Gosu V, Basith S, Durai P, Choi S. Molecular evolution and structural features of IRAK family members. PLoS One (2012) 7(11):e49771. doi:10.1371/journal.pone.0049771
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Gosu, V.1
Basith, S.2
Durai, P.3
Choi, S.4
-
30
-
-
23144449789
-
Ubiquitin signalling in the NF-κB pathway
-
doi:10.1038/ncb0805-758
-
Chen ZJ. Ubiquitin signalling in the NF-κB pathway. Nat Cell Biol (2005) 7(8):758-65. doi:10.1038/ncb0805-758
-
(2005)
Nat Cell Biol
, vol.7
, Issue.8
, pp. 758-765
-
-
Chen, Z.J.1
-
31
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
doi:10.1038/ni1255
-
Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, et al. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol (2005) 6(11):1087-95. doi:10.1038/ni1255
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1087-1095
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
Kawai, T.6
-
32
-
-
0742324860
-
TLR signaling pathways
-
doi:10.1016/j.smim.2003.10.003
-
Takeda K, Akira S. TLR signaling pathways. Semin Immunol (2004) 16(1):3-9. doi:10.1016/j.smim.2003.10.003
-
(2004)
Semin Immunol
, vol.16
, Issue.1
, pp. 3-9
-
-
Takeda, K.1
Akira, S.2
-
33
-
-
84877826018
-
Toll-like receptor signalling and their therapeutic targeting in colorectal cancer
-
doi:10.1016/j.intimp.2013.03.017
-
Moossavi S, Rezaei N. Toll-like receptor signalling and their therapeutic targeting in colorectal cancer. Int Immunopharmacol (2013) 16(2):199-209. doi:10.1016/j.intimp.2013.03.017
-
(2013)
Int Immunopharmacol
, vol.16
, Issue.2
, pp. 199-209
-
-
Moossavi, S.1
Rezaei, N.2
-
34
-
-
75649093343
-
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
-
doi:10.1038/nri2707
-
Abreu MT. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol (2010) 10(2):131-44. doi:10.1038/nri2707
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.2
, pp. 131-144
-
-
Abreu, M.T.1
-
35
-
-
33646374141
-
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice
-
doi:10.1128/IAI.74.5.2522-2536.2006
-
Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, et al. Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infect Immun (2006) 74(5):2522-36. doi:10.1128/IAI.74.5.2522-2536.2006
-
(2006)
Infect Immun
, vol.74
, Issue.5
, pp. 2522-2536
-
-
Khan, M.A.1
Ma, C.2
Knodler, L.A.3
Valdez, Y.4
Rosenberger, C.M.5
Deng, W.6
-
36
-
-
34250814435
-
TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium
-
doi:10.4049/jimmunol.179.1.566.
-
Lebeis SL, Bommarius B, Parkos CA, Sherman MA, Kalman D. TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium. J Immunol (2013) 179:566-77. doi:10.4049/jimmunol.179.1.566.
-
(2013)
J Immunol
, vol.179
, pp. 566-577
-
-
Lebeis, S.L.1
Bommarius, B.2
Parkos, C.A.3
Sherman, M.A.4
Kalman, D.5
-
37
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
doi:10.1128/IAI.68.12.7010-7017.2000
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun (2000) 68(12):7010-7. doi:10.1128/IAI.68.12.7010-7017.2000
-
(2000)
Infect Immun
, vol.68
, Issue.12
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
38
-
-
0035881675
-
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
doi:10.4049/jimmunol.167.4.1882
-
Gewirtz AT, Navas TA, Lyons S, Godowski PJ, Madara JL. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol (2001) 167(4):1882-5. doi:10.4049/jimmunol.167.4.1882
-
(2001)
J Immunol
, vol.167
, Issue.4
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
39
-
-
77957196909
-
Toll-like receptor (TLR) 7 and TLR8 expression on CD133 + cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression
-
doi:10.1016/j.ejca.2010.07.017
-
Grimm M, Kim M, Rosenwald A, Heemann U, Germer C-T, Waaga-Gasser AM, et al. Toll-like receptor (TLR) 7 and TLR8 expression on CD133 + cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression. Eur J Cancer (2010) 46(15):2849-57. doi:10.1016/j.ejca.2010.07.017
-
(2010)
Eur J Cancer
, vol.46
, Issue.15
, pp. 2849-2857
-
-
Grimm, M.1
Kim, M.2
Rosenwald, A.3
Heemann, U.4
Germer, C-T.5
Waaga-Gasser, A.M.6
-
40
-
-
47949099098
-
Origin and physiological roles of inflammation
-
doi:10.1038/nature07201
-
Medzhitov R. Origin and physiological roles of inflammation. Nature (2008) 454(7203):428-35. doi:10.1038/nature07201
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 428-435
-
-
Medzhitov, R.1
-
41
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
doi:10.1038/nri1630
-
Liew FY, Xu D, Brint EK, O'Neill LA. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 5(6):446-58. doi:10.1038/nri1630
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.6
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
42
-
-
84875932685
-
Negative regulatory approaches to the attenuation of toll-like receptor signaling.
-
doi:10.1038/emm.2013.28
-
Anwar MA, Basith S, Choi S. Negative regulatory approaches to the attenuation of toll-like receptor signaling. Exp Mol Med (2013) 45:e11. doi:10.1038/emm.2013.28
-
(2013)
Exp Mol Med
, vol.45
-
-
Anwar, M.A.1
Basith, S.2
Choi, S.3
-
43
-
-
76949107790
-
Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
-
doi:10.1038/nrmicro2297
-
Lebeer S, Vanderleyden J, De Keersmaecker SC. Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol (2010) 8(3):171-84. doi:10.1038/nrmicro2297
-
(2010)
Nat Rev Microbiol
, vol.8
, Issue.3
, pp. 171-184
-
-
Lebeer, S.1
Vanderleyden, J.2
De Keersmaecker, S.C.3
-
44
-
-
77649086402
-
Immune adaptations that maintain homeostasis with the intestinal microbiota
-
doi:10.1038/nri2710
-
Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol (2010) 10(3):159-69. doi:10.1038/nri2710
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.3
, pp. 159-169
-
-
Hooper, L.V.1
Macpherson, A.J.2
-
45
-
-
34247175428
-
The toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
-
doi:10.1016/j.immuni.2007.02.012
-
Xiao H, Gulen MF, Qin J, Yao J, Bulek K, Kish D, et al. The toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity (2007) 26(4):461-75. doi:10.1016/j.immuni.2007.02.012
-
(2007)
Immunity
, vol.26
, Issue.4
, pp. 461-475
-
-
Xiao, H.1
Gulen, M.F.2
Qin, J.3
Yao, J.4
Bulek, K.5
Kish, D.6
-
46
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
doi:10.1016/j.cell.2004.07.002
-
Rakoff NS, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 118(2):229-41. doi:10.1016/j.cell.2004.07.002
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff, N.S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
47
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
-
doi:10.1084/jem.20100199
-
Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J Exp Med (2010) 207(8):1625-36. doi:10.1084/jem.20100199
-
(2010)
J Exp Med
, vol.207
, Issue.8
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
Jones, Y.4
Gyulai, Z.5
Dai, R.M.6
-
48
-
-
4544243747
-
At the crossroads of inflammation and cancer
-
doi:10.1016/j.cell.2004.09.005
-
Clevers H. At the crossroads of inflammation and cancer. Cell (2004) 118(6):671-4. doi:10.1016/j.cell.2004.09.005
-
(2004)
Cell
, vol.118
, Issue.6
, pp. 671-674
-
-
Clevers, H.1
-
49
-
-
84888633713
-
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
-
doi:10.1038/nrc3611
-
Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat Rev Cancer (2013) 13(11):759-71. doi:10.1038/nrc3611
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.11
, pp. 759-771
-
-
Elinav, E.1
Nowarski, R.2
Thaiss, C.A.3
Hu, B.4
Jin, C.5
Flavell, R.A.6
-
50
-
-
79955564023
-
Intestinal inflammation and cancer
-
doi:10.1053/j.gastro.2011.01.057
-
Ullman TA, Itzkowitz SH. Intestinal inflammation and cancer. Gastroenterology (2011) 140(6):1807-16. doi:10.1053/j.gastro.2011.01.057
-
(2011)
Gastroenterology
, vol.140
, Issue.6
, pp. 1807-1816
-
-
Ullman, T.A.1
Itzkowitz, S.H.2
-
51
-
-
67650299380
-
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.
-
doi:10.1371/journal.pone.0006026
-
Uronis JM, Mühlbauer M, Herfarth HH, Rubinas TC, Jones GS, Jobin C. Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PLoS One (2009) 4(6):e6026. doi:10.1371/journal.pone.0006026
-
(2009)
PLoS One
, vol.4
, Issue.6
-
-
Uronis, J.M.1
Mühlbauer, M.2
Herfarth, H.H.3
Rubinas, T.C.4
Jones, G.S.5
Jobin, C.6
-
52
-
-
38649087921
-
Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis
-
doi:10.1073/pnas.0708594105
-
Swann JB, Vesely MD, Silva A, Sharkey J, Akira S, Schreiber RD, et al. Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. Proc Natl Acad Sci U S A (2008) 105(2):652-6. doi:10.1073/pnas.0708594105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.2
, pp. 652-656
-
-
Swann, J.B.1
Vesely, M.D.2
Silva, A.3
Sharkey, J.4
Akira, S.5
Schreiber, R.D.6
-
53
-
-
67349162130
-
Tumour necrosis factor and cancer
-
doi:10.1038/nrc2628
-
Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer (2009) 9(5):361-71. doi:10.1038/nrc2628
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.5
, pp. 361-371
-
-
Balkwill, F.1
-
54
-
-
0033596122
-
Control of development and immunity by rel transcription factors in Drosophila
-
doi:10.1038/sj.onc.1203223
-
Govind S. Control of development and immunity by rel transcription factors in Drosophila. Oncogene (1999) 18(49):6875-87. doi:10.1038/sj.onc.1203223
-
(1999)
Oncogene
, vol.18
, Issue.49
, pp. 6875-6887
-
-
Govind, S.1
-
55
-
-
0442323562
-
NF-κB: tumor promoter or suppressor?
-
doi:10.1016/j.tcb.2003.12.004
-
Perkins ND. NF-κB: tumor promoter or suppressor? Trends Cell Biol (2004) 14(2):64-9. doi:10.1016/j.tcb.2003.12.004
-
(2004)
Trends Cell Biol
, vol.14
, Issue.2
, pp. 64-69
-
-
Perkins, N.D.1
-
56
-
-
36549082403
-
Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
-
doi:10.1053/j.gastro.2007.09.008
-
Fukata M, Chen A, Vamadevan AS, Cohen J, Breglio K, Krishnareddy S, et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology (2007) 133(6):1869-81. doi:10.1053/j.gastro.2007.09.008
-
(2007)
Gastroenterology
, vol.133
, Issue.6
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
Cohen, J.4
Breglio, K.5
Krishnareddy, S.6
-
57
-
-
38849171267
-
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
-
doi:10.1172/JCI32453
-
Popivanova BK, Kitamura K, Wu Y, Kondo T, Kagaya T, Kaneko S, et al. Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest (2008) 118(2):560-70. doi:10.1172/JCI32453
-
(2008)
J Clin Invest
, vol.118
, Issue.2
, pp. 560-570
-
-
Popivanova, B.K.1
Kitamura, K.2
Wu, Y.3
Kondo, T.4
Kagaya, T.5
Kaneko, S.6
-
58
-
-
84862318128
-
The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models
-
doi:10.1007/s00535-011-0523-6
-
Oshima H, Oshima M. The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models. J Gastroenterol (2012) 47(2):97-106. doi:10.1007/s00535-011-0523-6
-
(2012)
J Gastroenterol
, vol.47
, Issue.2
, pp. 97-106
-
-
Oshima, H.1
Oshima, M.2
-
59
-
-
58149340659
-
Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer
-
doi:10.1158/1078-0432.CCR-08-1841
-
Ogino S, Kirkner GJ, Nosho K, Irahara N, Kure S, Shima K, et al. Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer. Clin Cancer Res (2008) 14(24):8221-7. doi:10.1158/1078-0432.CCR-08-1841
-
(2008)
Clin Cancer Res
, vol.14
, Issue.24
, pp. 8221-8227
-
-
Ogino, S.1
Kirkner, G.J.2
Nosho, K.3
Irahara, N.4
Kure, S.5
Shima, K.6
-
60
-
-
40749161012
-
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair
-
doi:10.4049/jimmunol.179.7.4808
-
Leaphart CL, Cavallo J, Gribar SC, Cetin S, Li J, Branca MF, et al. A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair. J Immunol (2007) 179(7):4808-20. doi:10.4049/jimmunol.179.7.4808
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4808-4820
-
-
Leaphart, C.L.1
Cavallo, J.2
Gribar, S.C.3
Cetin, S.4
Li, J.5
Branca, M.F.6
-
61
-
-
33747807305
-
The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis
-
doi:10.4049/jimmunol.177.5.3273
-
Jilling T, Simon D, Lu J, Meng FJ, Li D, Schy R, et al. The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis. J Immunol (2006) 177(5):3273-82. doi:10.4049/jimmunol.177.5.3273
-
(2006)
J Immunol
, vol.177
, Issue.5
, pp. 3273-3282
-
-
Jilling, T.1
Simon, D.2
Lu, J.3
Meng, F.J.4
Li, D.5
Schy, R.6
-
62
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells
-
doi:10.1053/j.gastro.2004.01.007
-
Otte JM, Cario E, Podolsky DK. Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology (2004) 126(4):1054-70. doi:10.1053/j.gastro.2004.01.007
-
(2004)
Gastroenterology
, vol.126
, Issue.4
, pp. 1054-1070
-
-
Otte, J.M.1
Cario, E.2
Podolsky, D.K.3
-
63
-
-
0035424901
-
Decreased expression of toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
doi:10.4049/jimmunol.167.3.1609
-
Abreu MT, Vora P, Faure E, Thomas LS, Arnold ET, Arditi M. Decreased expression of toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol (2001) 167(3):1609-16. doi:10.4049/jimmunol.167.3.1609
-
(2001)
J Immunol
, vol.167
, Issue.3
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
Thomas, L.S.4
Arnold, E.T.5
Arditi, M.6
-
64
-
-
0038781673
-
Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular toll-like receptor 4-MD-2 complex
-
doi:10.1128/IAI.71.6.3503-3511.2003
-
Suzuki M, Hisamatsu T, Podolsky DK. Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular toll-like receptor 4-MD-2 complex. Infect Immun (2003) 71(6):3503-11. doi:10.1128/IAI.71.6.3503-3511.2003
-
(2003)
Infect Immun
, vol.71
, Issue.6
, pp. 3503-3511
-
-
Suzuki, M.1
Hisamatsu, T.2
Podolsky, D.K.3
-
65
-
-
0037036469
-
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells
-
doi:10.1074/jbc.M110333200
-
Abreu MT, Arnold ET, Thomas LS, Gonsky R, Zhou Y, Hu B, et al. TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J Biol Chem (2002) 277(23):20431-7. doi:10.1074/jbc.M110333200
-
(2002)
J Biol Chem
, vol.277
, Issue.23
, pp. 20431-20437
-
-
Abreu, M.T.1
Arnold, E.T.2
Thomas, L.S.3
Gonsky, R.4
Zhou, Y.5
Hu, B.6
-
66
-
-
0037018107
-
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
-
doi:10.1084/jem.20011788
-
Hornef MW, Frisan T, Vandewalle A, Normark S, Richter-Dahlfors A. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med (2002) 195(5):559-70. doi:10.1084/jem.20011788
-
(2002)
J Exp Med
, vol.195
, Issue.5
, pp. 559-570
-
-
Hornef, M.W.1
Frisan, T.2
Vandewalle, A.3
Normark, S.4
Richter-Dahlfors, A.5
-
67
-
-
69249176159
-
Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells.
-
Doan HQ, Bowen KA, Jackson LA, Evers BM. Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells. Anticancer Res (2009) 29(7):2473-8.
-
(2009)
Anticancer Res
, vol.29
, Issue.7
, pp. 2473-2478
-
-
Doan, H.Q.1
Bowen, K.A.2
Jackson, L.A.3
Evers, B.M.4
-
68
-
-
33748271299
-
Cox-2 is regulated by toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine
-
doi:10.1053/j.gastro.2006.06.017
-
Fukata M, Chen A, Klepper A, Krishnareddy S, Vamadevan AS, Thomas LS, et al. Cox-2 is regulated by toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine. Gastroenterology (2006) 131(3):862-77. doi:10.1053/j.gastro.2006.06.017
-
(2006)
Gastroenterology
, vol.131
, Issue.3
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
Krishnareddy, S.4
Vamadevan, A.S.5
Thomas, L.S.6
-
69
-
-
78049484534
-
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker.
-
doi:10.1186/1479-5876-8-112
-
Cammarota R, Bertolini V, Pennesi G, Bucci EO, Gottardi O, Garlanda C, et al. The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker. J Transl Med (2010) 8(1):112. doi:10.1186/1479-5876-8-112
-
(2010)
J Transl Med
, vol.8
, Issue.1
, pp. 112
-
-
Cammarota, R.1
Bertolini, V.2
Pennesi, G.3
Bucci, E.O.4
Gottardi, O.5
Garlanda, C.6
-
70
-
-
37749029021
-
TLR4 signalling in the intestine in health and disease.
-
doi:10.1042/BST0351473
-
Fukata M, Abreu MT. TLR4 signalling in the intestine in health and disease. Biochem Soc Trans (2007) 35(Pt 6):1473-8. doi:10.1042/BST0351473
-
(2007)
Biochem Soc Trans
, vol.35
, Issue.PART 6
, pp. 1473-1478
-
-
Fukata, M.1
Abreu, M.T.2
-
71
-
-
0141781232
-
TLR signaling at the intestinal epithelial interface
-
doi:10.1179/096805103225002593
-
Abreu MT, Thomas LS, Arnold ET, Lukasek K, Michelsen KS, Arditi M. TLR signaling at the intestinal epithelial interface. J Endotoxin Res (2003) 9(5):322-30. doi:10.1179/096805103225002593
-
(2003)
J Endotoxin Res
, vol.9
, Issue.5
, pp. 322-330
-
-
Abreu, M.T.1
Thomas, L.S.2
Arnold, E.T.3
Lukasek, K.4
Michelsen, K.S.5
Arditi, M.6
-
72
-
-
14644403009
-
Toll-like receptor 9 - induced type I IFN protects mice from experimental colitis
-
doi:10.1172/JCI200522996C1
-
Katakura K, Lee J, Rachmilewitz D, Li G, Eckmann L, Raz E. Toll-like receptor 9 - induced type I IFN protects mice from experimental colitis. J Clin Invest (2005) 115(3):695-702. doi:10.1172/JCI200522996C1
-
(2005)
J Clin Invest
, vol.115
, Issue.3
, pp. 695-702
-
-
Katakura, K.1
Lee, J.2
Rachmilewitz, D.3
Li, G.4
Eckmann, L.5
Raz, E.6
-
73
-
-
67149121074
-
TLR4/MyD88/PI3K interactions regulate TLR4 signaling
-
doi:10.1189/jlb.1208763
-
Laird MH, Rhee SH, Perkins DJ, Medvedev AE, Piao W, Fenton MJ, et al. TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J Leukoc Biol (2009) 85(6):966-77. doi:10.1189/jlb.1208763
-
(2009)
J Leukoc Biol
, vol.85
, Issue.6
, pp. 966-977
-
-
Laird, M.H.1
Rhee, S.H.2
Perkins, D.J.3
Medvedev, A.E.4
Piao, W.5
Fenton, M.J.6
-
74
-
-
0141645559
-
Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells
-
doi:10.1136/gut.52.10.1472
-
Sheng H, Shao J, Townsend CM Jr, Evers BM. Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut (2003) 52(10):1472-8. doi:10.1136/gut.52.10.1472
-
(2003)
Gut
, vol.52
, Issue.10
, pp. 1472-1478
-
-
Sheng, H.1
Shao, J.2
Townsend Jr., C.M.3
Evers, B.M.4
-
75
-
-
34547932097
-
Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly
-
doi:10.1074/jbc.M700241200
-
Somanath PR, Kandel ES, Hay N, Byzova TV. Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly. J Biol Chem (2007) 282(31):22964-76. doi:10.1074/jbc.M700241200
-
(2007)
J Biol Chem
, vol.282
, Issue.31
, pp. 22964-22976
-
-
Somanath, P.R.1
Kandel, E.S.2
Hay, N.3
Byzova, T.V.4
-
76
-
-
79952236601
-
LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis
-
doi:10.1158/0008-5472.CAN-10-2833
-
Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, et al. LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Cancer Res (2011) 71(5):1989-98. doi:10.1158/0008-5472.CAN-10-2833
-
(2011)
Cancer Res
, vol.71
, Issue.5
, pp. 1989-1998
-
-
Hsu, R.Y.1
Chan, C.H.2
Spicer, J.D.3
Rousseau, M.C.4
Giannias, B.5
Rousseau, S.6
-
77
-
-
62149131898
-
Silencing of TLR4 decreases liver tumor burden in a murine model of colorectal metastasis and hepatic steatosis
-
doi:10.1245/s10434-009-0325-8
-
Earl TM, Nicoud IB, Pierce JM, Wright JP, Majoras NE, Rubin JE, et al. Silencing of TLR4 decreases liver tumor burden in a murine model of colorectal metastasis and hepatic steatosis. Ann Surg Oncol (2009) 16(4):1043-50. doi:10.1245/s10434-009-0325-8
-
(2009)
Ann Surg Oncol
, vol.16
, Issue.4
, pp. 1043-1050
-
-
Earl, T.M.1
Nicoud, I.B.2
Pierce, J.M.3
Wright, J.P.4
Majoras, N.E.5
Rubin, J.E.6
-
78
-
-
66149129910
-
Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB-dependent activation of the urokinase plasminogen activator system
-
doi:10.1038/sj.bjc.6604942
-
Killeen S, Wang J, Andrews E, Redmond H. Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-?B-dependent activation of the urokinase plasminogen activator system. Br J Cancer (2009) 100(10):1589-602. doi:10.1038/sj.bjc.6604942
-
(2009)
Br J Cancer
, vol.100
, Issue.10
, pp. 1589-1602
-
-
Killeen, S.1
Wang, J.2
Andrews, E.3
Redmond, H.4
-
79
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
doi:10.1172/JCI11991
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest (2001) 107(3):241-6. doi:10.1172/JCI11991
-
(2001)
J Clin Invest
, vol.107
, Issue.3
, pp. 241-246
-
-
Baldwin, A.S.1
-
80
-
-
85047696452
-
Role of tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL)
-
doi:10.1038/sj.leu.2402458
-
Hatta Y, Koeffler HP. Role of tumor suppressor genes in the development of adult T cell leukemia/lymphoma (ATLL). Leukemia (2002) 16(6):1069-85. doi:10.1038/sj.leu.2402458
-
(2002)
Leukemia
, vol.16
, Issue.6
, pp. 1069-1085
-
-
Hatta, Y.1
Koeffler, H.P.2
-
81
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
doi:10.1038/35009130
-
Ryan KM, Ernst MK, Rice NR, Vousden KH. Role of NF-kappaB in p53-mediated programmed cell death. Nature (2000) 404(6780):892-7. doi:10.1038/35009130
-
(2000)
Nature
, vol.404
, Issue.6780
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
82
-
-
77649272127
-
High expression of toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer
-
doi:10.1038/sj.bjc.6605558
-
Wang EL, Qian ZR, Nakasono M, Tanahashi T, Yoshimoto K, Bando Y, et al. High expression of toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer. Br J Cancer (2010) 102(5):908-15. doi:10.1038/sj.bjc.6605558
-
(2010)
Br J Cancer
, vol.102
, Issue.5
, pp. 908-915
-
-
Wang, E.L.1
Qian, Z.R.2
Nakasono, M.3
Tanahashi, T.4
Yoshimoto, K.5
Bando, Y.6
-
83
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
doi:10.1126/science.1140488
-
Rakoff NS, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science (2007) 317(5834):124-7. doi:10.1126/science.1140488
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 124-127
-
-
Rakoff, N.S.1
Medzhitov, R.2
-
84
-
-
77953196709
-
ERK activation drives intestinal tumorigenesis in Apc(min/+) mice
-
doi:10.1038/nm.2143
-
Lee SH, Hu LL, Gonzalez-Navajas J, Seo GS, Shen C, Brick J, et al. ERK activation drives intestinal tumorigenesis in Apc(min/+) mice. Nat Med (2010) 16(6):665-70. doi:10.1038/nm.2143
-
(2010)
Nat Med
, vol.16
, Issue.6
, pp. 665-670
-
-
Lee, S.H.1
Hu, L.L.2
Gonzalez-Navajas, J.3
Seo, G.S.4
Shen, C.5
Brick, J.6
-
85
-
-
77749279644
-
Myc proteins as therapeutic targets
-
doi:10.1038/onc.2009.512
-
Gustafson WC, Weiss WA. Myc proteins as therapeutic targets. Oncogene (2010) 29(9):1249-59. doi:10.1038/onc.2009.512
-
(2010)
Oncogene
, vol.29
, Issue.9
, pp. 1249-1259
-
-
Gustafson, W.C.1
Weiss, W.A.2
-
86
-
-
48549099080
-
C-Myc is a critical mediator of the phenotypes of Apc loss in the intestine
-
doi:10.1158/0008-5472.CAN-07-5558
-
Wilkins JA, Sansom OJ. C-Myc is a critical mediator of the phenotypes of Apc loss in the intestine. Cancer Res (2008) 68(13):4963-6. doi:10.1158/0008-5472.CAN-07-5558
-
(2008)
Cancer Res
, vol.68
, Issue.13
, pp. 4963-4966
-
-
Wilkins, J.A.1
Sansom, O.J.2
-
87
-
-
77953218649
-
Microflora in colorectal cancer: a friend to fear
-
doi:10.1038/nm0610-639
-
Fukata M, Abreu MT. Microflora in colorectal cancer: a friend to fear. Nat Med (2010) 16(6):639-41. doi:10.1038/nm0610-639
-
(2010)
Nat Med
, vol.16
, Issue.6
, pp. 639-641
-
-
Fukata, M.1
Abreu, M.T.2
-
88
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
doi:10.1016/0092-8674(81)90021-0
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell (1991) 66(3):589-600. doi:10.1016/0092-8674(81)90021-0
-
(1991)
Cell
, vol.66
, Issue.3
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
-
89
-
-
0034098691
-
Biology of the adenomatous polyposis coli tumor suppressor.
-
Goss KH, Groden J. Biology of the adenomatous polyposis coli tumor suppressor. J Clin Oncol (2000) 18(9):1967-79.
-
(2000)
J Clin Oncol
, vol.18
, Issue.9
, pp. 1967-1979
-
-
Goss, K.H.1
Groden, J.2
-
90
-
-
0037318946
-
Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis.
-
doi:10.1186/cc1854
-
Opal SM, Esmon CT. Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis. Crit Care (2002) 7(1):23. doi:10.1186/cc1854
-
(2002)
Crit Care
, vol.7
, Issue.1
, pp. 23
-
-
Opal, S.M.1
Esmon, C.T.2
-
91
-
-
77950542752
-
Targeting toll-like receptors: emerging therapeutics?
-
doi:10.1038/nrd3203
-
Hennessy EJ, Parker AE, O'Neill LA. Targeting toll-like receptors: emerging therapeutics? Nat Rev Drug Discov (2010) 9(4):293-307. doi:10.1038/nrd3203
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.4
, pp. 293-307
-
-
Hennessy, E.J.1
Parker, A.E.2
O'Neill, L.A.3
-
92
-
-
84859920121
-
Toll-like receptor genes and their association with colon and rectal cancer development and prognosis
-
doi:10.1002/ijc.26314
-
Slattery ML, Herrick JS, Bondurant KL, Wolff RK. Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. Int J Cancer (2012) 130(12):2974-80. doi:10.1002/ijc.26314
-
(2012)
Int J Cancer
, vol.130
, Issue.12
, pp. 2974-2980
-
-
Slattery, M.L.1
Herrick, J.S.2
Bondurant, K.L.3
Wolff, R.K.4
-
93
-
-
84871617221
-
Functional polymorphisms of toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans
-
doi:10.1016/j.dld.2012.08.006
-
Pimentel-Nunes P, Teixeira AL, Pereira C, Gomes M, Brandao C, Rodrigues C, et al. Functional polymorphisms of toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans. Dig Liver Dis (2013) 45(1):63-9. doi:10.1016/j.dld.2012.08.006
-
(2013)
Dig Liver Dis
, vol.45
, Issue.1
, pp. 63-69
-
-
Pimentel-Nunes, P.1
Teixeira, A.L.2
Pereira, C.3
Gomes, M.4
Brandao, C.5
Rodrigues, C.6
-
94
-
-
84894425546
-
Positive link between variant toll-like receptor 4 (Asp299Gly and Thr399Ile) and colorectal cancer patients with advanced stage and lymph node metastasis
-
doi:10.1007/s13277-013-1075-6
-
Omrane I, Baroudi O, Kourda N, Bignon YJ, Uhrhammer N, Desrichard A, et al. Positive link between variant toll-like receptor 4 (Asp299Gly and Thr399Ile) and colorectal cancer patients with advanced stage and lymph node metastasis. Tumour Biol (2013) 35(1):545-51. doi:10.1007/s13277-013-1075-6
-
(2013)
Tumour Biol
, vol.35
, Issue.1
, pp. 545-551
-
-
Omrane, I.1
Baroudi, O.2
Kourda, N.3
Bignon, Y.J.4
Uhrhammer, N.5
Desrichard, A.6
-
95
-
-
30444459750
-
Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria
-
doi:10.1073/pnas.0506803102
-
Mockenhaupt FP, Cramer JP, Hamann L, Stegemann MS, Eckert J, Oh NR, et al. Toll-like receptor (TLR) polymorphisms in African children: common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci U S A (2006) 103(1):177-82. doi:10.1073/pnas.0506803102
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.1
, pp. 177-182
-
-
Mockenhaupt, F.P.1
Cramer, J.P.2
Hamann, L.3
Stegemann, M.S.4
Eckert, J.5
Oh, N.R.6
-
96
-
-
34248635673
-
Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8-251 polymorphisms in the risk for the development of distal gastric cancer.
-
doi:10.1186/1471-2407-7-70
-
Garza-Gonzalez E, Bosques-Padilla FJ, Mendoza-Ibarra SI, Flores-Gutierrez JP, Maldonado-Garza HJ, Perez-Perez GI. Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8-251 polymorphisms in the risk for the development of distal gastric cancer. BMC Cancer (2007) 7(1):70. doi:10.1186/1471-2407-7-70
-
(2007)
BMC Cancer
, vol.7
, Issue.1
, pp. 70
-
-
Garza-Gonzalez, E.1
Bosques-Padilla, F.J.2
Mendoza-Ibarra, S.I.3
Flores-Gutierrez, J.P.4
Maldonado-Garza, H.J.5
Perez-Perez, G.I.6
-
97
-
-
44649115688
-
Functional consequences of toll-like receptor 4 polymorphisms.
-
doi:10.2119/2007-00135.Ferwerda
-
Ferwerda B, Mccall MB, Verheijen K, Kullberg BJ, Van Der Ven AJ, Van Der Meer JW, et al. Functional consequences of toll-like receptor 4 polymorphisms. Mol Med (2008) 14(5-6):346-52. doi:10.2119/2007-00135.Ferwerda
-
(2008)
Mol Med
, vol.14
, Issue.5-6
, pp. 346-352
-
-
Ferwerda, B.1
Mccall, M.B.2
Verheijen, K.3
Kullberg, B.J.4
Van Der Ven, A.J.5
Van Der Meer, J.W.6
-
98
-
-
33745815169
-
Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer
-
doi:10.1111/j.1399-0004.2006.00651.x
-
Boraska Jelavic T, Barisic M, Drmic Hofman I, Boraska V, Vrdoljak E, Peruzovic M, et al. Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer. Clin Genet (2006) 70(2):156-60. doi:10.1111/j.1399-0004.2006.00651.x
-
(2006)
Clin Genet
, vol.70
, Issue.2
, pp. 156-160
-
-
Boraska Jelavic, T.1
Barisic, M.2
Drmic Hofman, I.3
Boraska, V.4
Vrdoljak, E.5
Peruzovic, M.6
-
99
-
-
84899428429
-
Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis.
-
doi:10.1371/journal.pone.0093904
-
Li XX, Sun GP, Meng J, Li X, Tang YX, Li Z, et al. Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis. PLoS One (2014) 9(4):e93904. doi:10.1371/journal.pone.0093904
-
(2014)
PLoS One
, vol.9
, Issue.4
-
-
Li, X.X.1
Sun, G.P.2
Meng, J.3
Li, X.4
Tang, Y.X.5
Li, Z.6
-
100
-
-
55449103507
-
Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes
-
doi:10.1111/j.1365-2249.2008.03776.x
-
Santini D, Angeletti S, Ruzzo A, Dicuonzo G, Galluzzo S, Vincenzi B, et al. Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes. Clin Exp Immunol (2008) 154(3):360-4. doi:10.1111/j.1365-2249.2008.03776.x
-
(2008)
Clin Exp Immunol
, vol.154
, Issue.3
, pp. 360-364
-
-
Santini, D.1
Angeletti, S.2
Ruzzo, A.3
Dicuonzo, G.4
Galluzzo, S.5
Vincenzi, B.6
-
101
-
-
84905655650
-
Correlation of Asp299Gly and Thr399Ile polymorphisms in toll-like receptor 4 gene with digestive cancer risk: a meta-analysis
-
doi:10.3892/br.2012.32
-
Zhao X, Kang S, Liu L, Zhang D. Correlation of Asp299Gly and Thr399Ile polymorphisms in toll-like receptor 4 gene with digestive cancer risk: a meta-analysis. Biomed Rep (2013) 1(2):294-302. doi:10.3892/br.2012.32
-
(2013)
Biomed Rep
, vol.1
, Issue.2
, pp. 294-302
-
-
Zhao, X.1
Kang, S.2
Liu, L.3
Zhang, D.4
-
102
-
-
79955531832
-
TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer
-
doi:10.1016/j.ejca.2010.12.011
-
Castro FA, Forsti A, Buch S, Kalthoff H, Krauss C, Bauer M, et al. TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer (2011) 47(8):1203-10. doi:10.1016/j.ejca.2010.12.011
-
(2011)
Eur J Cancer
, vol.47
, Issue.8
, pp. 1203-1210
-
-
Castro, F.A.1
Forsti, A.2
Buch, S.3
Kalthoff, H.4
Krauss, C.5
Bauer, M.6
-
103
-
-
70350588993
-
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer
-
doi:10.1007/s10552-009-9427-7
-
Tsilidis KK, Helzlsouer KJ, Smith MW, Grinberg V, Hoffman-Bolton J, Clipp SL, et al. Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. Cancer Causes Control (2009) 20(9):1739-51. doi:10.1007/s10552-009-9427-7
-
(2009)
Cancer Causes Control
, vol.20
, Issue.9
, pp. 1739-1751
-
-
Tsilidis, K.K.1
Helzlsouer, K.J.2
Smith, M.W.3
Grinberg, V.4
Hoffman-Bolton, J.5
Clipp, S.L.6
-
104
-
-
33645238579
-
Polymorphism of CD14 gene but not the mutation of TLR4 gene is associated with colorectal cancer in Chinese patients.
-
doi:10.1111/j.1440-1746.2005.04156.x
-
Guo Q, Zhu J, Xia B. Polymorphism of CD14 gene but not the mutation of TLR4 gene is associated with colorectal cancer in Chinese patients. J Gastroenterol Hepatol (2006) 21(1 Pt 1):92-7. doi:10.1111/j.1440-1746.2005.04156.x
-
(2006)
J Gastroenterol Hepatol
, vol.21
, Issue.1 PART 1
, pp. 92-97
-
-
Guo, Q.1
Zhu, J.2
Xia, B.3
-
105
-
-
79957828056
-
LBP and CD14 polymorphisms correlate with increased colorectal carcinoma risk in Han Chinese
-
doi:10.3748/wjg.v17.i18.2326
-
Chen R, Luo FK, Wang YL, Tang JL, Liu YS. LBP and CD14 polymorphisms correlate with increased colorectal carcinoma risk in Han Chinese. World J Gastroenterol (2011) 17(18):2326-31. doi:10.3748/wjg.v17.i18.2326
-
(2011)
World J Gastroenterol
, vol.17
, Issue.18
, pp. 2326-2331
-
-
Chen, R.1
Luo, F.K.2
Wang, Y.L.3
Tang, J.L.4
Liu, Y.S.5
-
106
-
-
33750839061
-
Polymorphisms within inflammatory genes and colorectal cancer.
-
doi:10.1186/1477-5751-5-15
-
Landi S, Gemignani F, Bottari F, Gioia-Patricola L, Guino E, Cambray M, et al. Polymorphisms within inflammatory genes and colorectal cancer. J Negat Results Biomed (2006) 5:15. doi:10.1186/1477-5751-5-15
-
(2006)
J Negat Results Biomed
, vol.5
, pp. 15
-
-
Landi, S.1
Gemignani, F.2
Bottari, F.3
Gioia-Patricola, L.4
Guino, E.5
Cambray, M.6
-
107
-
-
79959235834
-
Variant toll-like receptor4 (Asp299Gly and Thr399Ile alleles) and toll-like receptor2 (Arg753Gln and Arg677Trp alleles) in colorectal cancer
-
doi:010.02/ijaai.9199
-
Davoodi H, Seow HF. Variant toll-like receptor4 (Asp299Gly and Thr399Ile alleles) and toll-like receptor2 (Arg753Gln and Arg677Trp alleles) in colorectal cancer. Iran J Allergy Asthma Immunol (2011) 10(2):91-9. doi:010.02/ijaai.9199
-
(2011)
Iran J Allergy Asthma Immunol
, vol.10
, Issue.2
, pp. 91-99
-
-
Davoodi, H.1
Seow, H.F.2
-
108
-
-
84902996977
-
Correlation between genetic polymorphisms within IL-1B and TLR4 genes and cancer risk in a Russian population: a case-control study
-
doi:10.1007/s13277-014-1633-6
-
Kutikhin AG, Yuzhalin AE, Volkov AN, Zhivotovskiy AS, Brusina EB. Correlation between genetic polymorphisms within IL-1B and TLR4 genes and cancer risk in a Russian population: a case-control study. Tumour Biol (2014) 35(5):4821-30. doi:10.1007/s13277-014-1633-6
-
(2014)
Tumour Biol
, vol.35
, Issue.5
, pp. 4821-4830
-
-
Kutikhin, A.G.1
Yuzhalin, A.E.2
Volkov, A.N.3
Zhivotovskiy, A.S.4
Brusina, E.B.5
-
109
-
-
77951583810
-
Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis
-
doi:10.4049/jimmunol.0901271
-
Takahashi K, Sugi Y, Hosono A, Kaminogawa S. Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis. J Immunol (2009) 183(10):6522-9. doi:10.4049/jimmunol.0901271
-
(2009)
J Immunol
, vol.183
, Issue.10
, pp. 6522-6529
-
-
Takahashi, K.1
Sugi, Y.2
Hosono, A.3
Kaminogawa, S.4
-
110
-
-
84855901602
-
Measuring dynamic changes in histone modifications and nucleosome density during activated transcription in budding yeast
-
doi:10.1007/978-1-61779-477-3_2
-
Govind CK, Ginsburg D, Hinnebusch AG. Measuring dynamic changes in histone modifications and nucleosome density during activated transcription in budding yeast. Methods Mol Biol (2012) 833:15-27. doi:10.1007/978-1-61779-477-3_2
-
(2012)
Methods Mol Biol
, vol.833
, pp. 15-27
-
-
Govind, C.K.1
Ginsburg, D.2
Hinnebusch, A.G.3
-
111
-
-
80053922802
-
Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells
-
doi:10.1074/jbc.M111.271007
-
Takahashi K, Sugi Y, Nakano K, Tsuda M, Kurihara K, Hosono A, et al. Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells. J Biol Chem (2011) 286(41):35755-62. doi:10.1074/jbc.M111.271007
-
(2011)
J Biol Chem
, vol.286
, Issue.41
, pp. 35755-35762
-
-
Takahashi, K.1
Sugi, Y.2
Nakano, K.3
Tsuda, M.4
Kurihara, K.5
Hosono, A.6
-
112
-
-
0038676409
-
Inhibition of histone deacetylase activity by butyrate.
-
Davie JR. Inhibition of histone deacetylase activity by butyrate. J Nutr (2003) 133(7 Suppl):2485S-93S.
-
(2003)
J Nutr
, vol.133
, Issue.7 SUPPL.
-
-
Davie, J.R.1
-
113
-
-
48649087037
-
Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
-
doi:10.1016/j.jnutbio.2007.08.002
-
Waldecker M, Kautenburger T, Daumann H, Busch C, Schrenk D. Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J Nutr Biochem (2008) 19(9):587-93. doi:10.1016/j.jnutbio.2007.08.002
-
(2008)
J Nutr Biochem
, vol.19
, Issue.9
, pp. 587-593
-
-
Waldecker, M.1
Kautenburger, T.2
Daumann, H.3
Busch, C.4
Schrenk, D.5
-
114
-
-
77952381089
-
Regulation of toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis
-
doi:10.1177/1753425909339231
-
Vamadevan AS, Fukata M, Arnold ET, Thomas LS, Hsu D, Abreu MT. Regulation of toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis. Innate Immun (2010) 16(2):93-103. doi:10.1177/1753425909339231
-
(2010)
Innate Immun
, vol.16
, Issue.2
, pp. 93-103
-
-
Vamadevan, A.S.1
Fukata, M.2
Arnold, E.T.3
Thomas, L.S.4
Hsu, D.5
Abreu, M.T.6
-
115
-
-
34249677845
-
Therapeutic targeting of innate immunity with toll-like receptor agonists and antagonists
-
doi:10.1038/nm1589
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with toll-like receptor agonists and antagonists. Nat Med (2007) 13(5):552-9. doi:10.1038/nm1589
-
(2007)
Nat Med
, vol.13
, Issue.5
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
116
-
-
0037290876
-
Mammalian toll-like receptors
-
doi:10.1016/S0952-7915(03)00005-0
-
Akira S. Mammalian toll-like receptors. Curr Opin Immunol (2003) 15(1):5-11. doi:10.1016/S0952-7915(03)00005-0
-
(2003)
Curr Opin Immunol
, vol.15
, Issue.1
, pp. 5-11
-
-
Akira, S.1
-
117
-
-
0025828456
-
Treatment of cancer patients with endotoxin induces release of endogenous cytokines
-
doi:10.1159/000163659
-
Mackensen A, Galanos C, Engelhardt R. Treatment of cancer patients with endotoxin induces release of endogenous cytokines. Pathobiology (1991) 59(4):264-7. doi:10.1159/000163659
-
(1991)
Pathobiology
, vol.59
, Issue.4
, pp. 264-267
-
-
Mackensen, A.1
Galanos, C.2
Engelhardt, R.3
-
118
-
-
0025856680
-
Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients.
-
Engelhardt R, Mackensen A, Galanos C. Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients. Cancer Res (1991) 51(10):2524-30.
-
(1991)
Cancer Res
, vol.51
, Issue.10
, pp. 2524-2530
-
-
Engelhardt, R.1
Mackensen, A.2
Galanos, C.3
-
119
-
-
84872801225
-
Trial watch: experimental toll-like receptor agonists for cancer therapy
-
doi:10.4161/onci.20696
-
Galluzzi L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, et al. Trial watch: experimental toll-like receptor agonists for cancer therapy. Oncoimmunology (2012) 1(5):699-716. doi:10.4161/onci.20696
-
(2012)
Oncoimmunology
, vol.1
, Issue.5
, pp. 699-716
-
-
Galluzzi, L.1
Vacchelli, E.2
Eggermont, A.3
Fridman, W.H.4
Galon, J.5
Sautes-Fridman, C.6
-
120
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
doi:10.1126/science.1138963
-
Mata-Haro V, Cekic C, Martin M, Chilton PM, Casella CR, Mitchell TC. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science (2007) 316(5831):1628-32. doi:10.1126/science.1138963
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
Chilton, P.M.4
Casella, C.R.5
Mitchell, T.C.6
-
121
-
-
0036789814
-
Taking toll: lipid A mimetics as adjuvants and immunomodulators.
-
doi:10.1016/S0966-842X(02)02426-5
-
Persing DH, Coler RN, Lacy MJ, Johnson DA, Baldridge JR, Hershberg RM, et al. Taking toll: lipid A mimetics as adjuvants and immunomodulators. Trends Microbiol (2002) 10(10):s32-7. doi:10.1016/S0966-842X(02)02426-5
-
(2002)
Trends Microbiol
, vol.10
, Issue.10
-
-
Persing, D.H.1
Coler, R.N.2
Lacy, M.J.3
Johnson, D.A.4
Baldridge, J.R.5
Hershberg, R.M.6
-
122
-
-
33947187647
-
Toll-free vaccines?
-
doi:10.1038/nbt0307-303
-
Krieg AM. Toll-free vaccines? Nat Biotechnol (2007) 25(3):303-5. doi:10.1038/nbt0307-303
-
(2007)
Nat Biotechnol
, vol.25
, Issue.3
, pp. 303-305
-
-
Krieg, A.M.1
-
123
-
-
84868101247
-
Roles of toll-like receptors in cancer: a double-edged sword for defense and offense
-
doi:10.1007/s12272-012-0802-7
-
Basith S, Manavalan B, Yoo TH, Kim SG, Choi S. Roles of toll-like receptors in cancer: a double-edged sword for defense and offense. Arch Pharm Res (2012) 35(8):1297-316. doi:10.1007/s12272-012-0802-7
-
(2012)
Arch Pharm Res
, vol.35
, Issue.8
, pp. 1297-1316
-
-
Basith, S.1
Manavalan, B.2
Yoo, T.H.3
Kim, S.G.4
Choi, S.5
-
124
-
-
19444386768
-
Antitumour effect of OM-174 and cyclophosphamide on murine B16 melanoma in different experimental conditions.
-
doi:10.1016/j.intimp.2005.02.013
-
D'Agostini C, Pica F, Febbraro G, Grelli S, Chiavaroli C, Garaci E. Antitumour effect of OM-174 and cyclophosphamide on murine B16 melanoma in different experimental conditions. Int Immunopharmacol (2005) 5(7-8):1205-12. doi:10.1016/j.intimp.2005.02.013
-
(2005)
Int Immunopharmacol
, vol.5
, Issue.7-8
, pp. 1205-1212
-
-
D'Agostini, C.1
Pica, F.2
Febbraro, G.3
Grelli, S.4
Chiavaroli, C.5
Garaci, E.6
-
125
-
-
33751184377
-
The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase
-
doi:10.1016/j.ijrobp.2006.07.1381
-
De Ridder M, Verovski VN, Chiavaroli C, Van Den Berge DL, Monsaert C, Law K, et al. The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase. Int J Radiat Oncol Biol Phys (2006) 66(5):1473-80. doi:10.1016/j.ijrobp.2006.07.1381
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, Issue.5
, pp. 1473-1480
-
-
De Ridder, M.1
Verovski, V.N.2
Chiavaroli, C.3
Van Den Berge, D.L.4
Monsaert, C.5
Law, K.6
-
126
-
-
84875486261
-
Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors.
-
doi:10.1186/1471-2407-13-172
-
Isambert N, Fumoleau P, Paul C, Ferrand C, Zanetta S, Bauer J, et al. Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors. BMC Cancer (2013) 13:172. doi:10.1186/1471-2407-13-172
-
(2013)
BMC Cancer
, vol.13
, pp. 172
-
-
Isambert, N.1
Fumoleau, P.2
Paul, C.3
Ferrand, C.4
Zanetta, S.5
Bauer, J.6
-
127
-
-
27244449289
-
Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
-
doi:10.1200/JCO.2005.13.011
-
Butts C, Murray N, Maksymiuk A, Goss G, Marshall E, Soulieres D, et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol (2005) 23(27):6674-81. doi:10.1200/JCO.2005.13.011
-
(2005)
J Clin Oncol
, vol.23
, Issue.27
, pp. 6674-6681
-
-
Butts, C.1
Murray, N.2
Maksymiuk, A.3
Goss, G.4
Marshall, E.5
Soulieres, D.6
-
128
-
-
84883461036
-
Victories and deceptions in tumor immunology: Stimuvax.
-
doi:10.4161/onci.23687
-
Kroemer G, Zitvogel L, Galluzzi L. Victories and deceptions in tumor immunology: Stimuvax. Oncoimmunology (2013) 2(1):e23687. doi:10.4161/onci.23687
-
(2013)
Oncoimmunology
, vol.2
, Issue.1
-
-
Kroemer, G.1
Zitvogel, L.2
Galluzzi, L.3
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