Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 288, Issue 5 51-5, 2005, Pages

  Fukata, Masayuki ^a   Michelsen, Kathrin S ^e   Eri, Rajaraman ^c   Thomas, Lisa S ^c   Hu, Bing ^e   Lukasek, Katie ^c   Nast, Cynthia C ^e   Lechago, Juan ^e   Xu, Ruliang ^a,b   Naiki, Yoshikazu ^d   Soliman, Antoine ^d   Arditi, Moshe ^d   Abreu, Maria T ^a,b  

^a Inflammatory Bowel Disease Center   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c Inflammatory Bowel Disease Center   (United States)

^d BURNS AND ALLEN RESEARCH INSTITUTE   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Dextran sodium sulfate; Inflammatory bowel disease; Innate immunity; Neutrophil chemotaxis

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; DEXTRAN SULFATE; MACROPHAGE INFLAMMATORY PROTEIN 2; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL TRANSLOCATION; CELL PROLIFERATION; COLITIS; CONTROLLED STUDY; CRYPT CELL; CYTOKINE RELEASE; ENTERITIS; ESCHERICHIA COLI; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; MACROPHAGE; MESENTERY LYMPH NODE; MOUSE; MUCOSAL IMMUNITY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS FLUORESCENS; RECTUM HEMORRHAGE; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; COLITIS; DEXTRAN SULFATE; GENE EXPRESSION; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHILS; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; TOLL-LIKE RECEPTOR 4;

EID: 20244372724     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00328.2004     Document Type: Article

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