Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

Nature Immunology

Volumn 7, Issue 2, 2006, Pages 148-155

  Mansell, Ashley ^a   Smith, Rosealee ^a   Doyle, Sarah L ^b   Gray, Pearl ^b   Fenner, Jennifer E ^a   Crack, Peter J ^a   Nicholson, Sandra E ^c   Hilton, Douglas J ^c   O'Neill L A J , Luke A J ^b   Hertzog, Paul J ^a  

^a MONASH UNIVERSITY   (Australia)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BRUTON TYROSINE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN MAL; SUPPRESSOR OF CYTOKINE SIGNALING 1; SYNAPTOTAGMIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSTIMULATION; INFLAMMATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE INJURY; TRANSACTIVATION; UBIQUITINATION;

ANIMALS; CARRIER PROTEINS; CELL LINE; HUMANS; IMMUNITY, NATURAL; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED CBA; MICE, KNOCKOUT; MYELIN PROTEINS; PHOSPHORYLATION; PROTEOLIPIDS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR RELA; TYROSINE; UBIQUITIN;

EID: 31344467156     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1299     Document Type: Article

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