-
1
-
-
84863625224
-
A CXCL1 paracrine network links cancer chemoresistance and metastasis
-
Acharyya, S., Oskarsson, T., Vanharanta, S., Malladi, S., Kim, J., Morris, P. G., et al. (2012). A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 150, 165-178. doi: 10.1016/j.cell.2012.04.042
-
(2012)
Cell
, vol.150
, pp. 165-178
-
-
Acharyya, S.1
Oskarsson, T.2
Vanharanta, S.3
Malladi, S.4
Kim, J.5
Morris, P.G.6
-
2
-
-
67651091693
-
In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives
-
Ahlskog, J. K. J., Dumelin, C. E., Trüssel, S., Mårlind, J., and Neri, D. (2009). In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives. Bioorg. Med. Chem. Lett. 19, 4851-4856. doi: 10.1016/j.bmcl.2009.06.022
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 4851-4856
-
-
Ahlskog, J.K.J.1
Dumelin, C.E.2
Trüssel, S.3
Mårlind, J.4
Neri, D.5
-
3
-
-
84919863195
-
MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies
-
Baek, G., Tse, Y. F., Hu, Z., Cox, D., Buboltz, N., McCue, P., et al. (2014). MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies. Cell Rep. 9, 2233-2249. doi: 10.1016/j.celrep.2014.11.025
-
(2014)
Cell Rep
, vol.9
, pp. 2233-2249
-
-
Baek, G.1
Tse, Y.F.2
Hu, Z.3
Cox, D.4
Buboltz, N.5
McCue, P.6
-
4
-
-
84940878452
-
Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival
-
Baenke, F., Dubuis, S., Brault, C., Weigelt, B., Dankworth, B., Griffiths, B., et al. (2015). Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival. J. Pathol. 237, 152-165. doi: 10.1002/path.4562
-
(2015)
J. Pathol
, vol.237
, pp. 152-165
-
-
Baenke, F.1
Dubuis, S.2
Brault, C.3
Weigelt, B.4
Dankworth, B.5
Griffiths, B.6
-
5
-
-
84886377822
-
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
-
Baginska, J., Viry, E., Berchem, G., Poli, A., Noman, M. Z., van Moer, K., et al. (2013). Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. Proc. Natl. Acad. Sci. U.S.A. 110, 17450-17455. doi: 10.1073/pnas.1304790110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 17450-17455
-
-
Baginska, J.1
Viry, E.2
Berchem, G.3
Poli, A.4
Noman, M.Z.5
van Moer, K.6
-
6
-
-
84865835733
-
Targeting the metabolic microenvironment of tumors
-
Bailey, K. M., Wojtkowiak, J. W., Hashim, A. I., and Gillies, R. J. (2012). Targeting the metabolic microenvironment of tumors. Adv. Pharmacol. 65, 63-107. doi: 10.1016/B978-0-12-397927-8.00004-X
-
(2012)
Adv. Pharmacol
, vol.65
, pp. 63-107
-
-
Bailey, K.M.1
Wojtkowiak, J.W.2
Hashim, A.I.3
Gillies, R.J.4
-
7
-
-
84255170452
-
Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide
-
Barsoum, I. B., Hamilton, T. K., Li, X., Cotechini, T., Miles, E. A., Siemens, D. R., et al. (2011). Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide. Cancer Res. 71, 7433-7441. doi: 10.1158/0008-5472.CAN-11-2104
-
(2011)
Cancer Res
, vol.71
, pp. 7433-7441
-
-
Barsoum, I.B.1
Hamilton, T.K.2
Li, X.3
Cotechini, T.4
Miles, E.A.5
Siemens, D.R.6
-
8
-
-
84918591282
-
Mechanisms of hypoxia-mediated immune escape in cancer
-
Barsoum, I. B., Koti, M., Siemens, D. R., and Graham, C. H. (2014a). Mechanisms of hypoxia-mediated immune escape in cancer. Cancer Res. 74, 7185-7190. doi: 10.1158/0008-5472.CAN-14-2598
-
(2014)
Cancer Res
, vol.74
, pp. 7185-7190
-
-
Barsoum, I.B.1
Koti, M.2
Siemens, D.R.3
Graham, C.H.4
-
9
-
-
84893872087
-
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells
-
Barsoum, I. B., Smallwood, C. A., Siemens, D. R., and Graham, C. H. (2014b). A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells. Cancer Res. 74, 665-674. doi: 10.1158/0008-5472.CAN-13-0992
-
(2014)
Cancer Res
, vol.74
, pp. 665-674
-
-
Barsoum, I.B.1
Smallwood, C.A.2
Siemens, D.R.3
Graham, C.H.4
-
10
-
-
84873989235
-
Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM.CAIX in immunocompetent mouse models
-
Birkhäuser, F. D., Koya, R. C., Neufeld, C., Rampersaud, E. N., Lu, X., Micewicz, E. D., et al. (2013). Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM.CAIX in immunocompetent mouse models. J. Immunother. 36, 102-111. doi: 10.1097/CJI.0b013e31827bec97
-
(2013)
J. Immunother
, vol.36
, pp. 102-111
-
-
Birkhäuser, F.D.1
Koya, R.C.2
Neufeld, C.3
Rampersaud, E.N.4
Lu, X.5
Micewicz, E.D.6
-
11
-
-
84918565034
-
Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport
-
Bola, B. M., Chadwick, A. L., Michopoulos, F., Blount, K. G., Telfer, B. A., Williams, K. J., et al. (2014). Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport. Mol. Cancer Ther. 13, 2805-2816. doi: 10.1158/1535-7163.MCT-13-1091
-
(2014)
Mol. Cancer Ther
, vol.13
, pp. 2805-2816
-
-
Bola, B.M.1
Chadwick, A.L.2
Michopoulos, F.3
Blount, K.G.4
Telfer, B.A.5
Williams, K.J.6
-
12
-
-
79551628206
-
Hypoxia and energetic tumour metabolism
-
Brahimi-Horn, M. C., Bellot, G., and Pouysségur, J. (2011). Hypoxia and energetic tumour metabolism. Curr. Opin. Genet. Dev. 21, 67-72. doi: 10.1016/j.gde.2010.10.006
-
(2011)
Curr. Opin. Genet. Dev
, vol.21
, pp. 67-72
-
-
Brahimi-Horn, M.C.1
Bellot, G.2
Pouysségur, J.3
-
13
-
-
36849066978
-
Hypoxia and cancer
-
Brahimi-Horn, M. C., Chiche, J., and Pouyssegur, J. (2007). Hypoxia and cancer. J. Mol. Med. 85, 1301-1307. doi: 10.1007/s00109-007-0281-3
-
(2007)
J. Mol. Med
, vol.85
, pp. 1301-1307
-
-
Brahimi-Horn, M.C.1
Chiche, J.2
Pouyssegur, J.3
-
14
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer, J. R., Tykodi, S. S., Chow, L. Q., Hwu, W. J., Topalian, S. L., Hwu, P., et al. (2012). Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366, 2455-2465. doi: 10.1056/NEJMoa1200694
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
-
15
-
-
70350545729
-
Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions
-
Bronte, V. (2009). Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions. Eur. J. Immunol. 39, 2670-2672. doi: 10.1002/eji.200939892
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 2670-2672
-
-
Bronte, V.1
-
16
-
-
1542399581
-
Optimization of radioimmunotherapy of renal cell carcinoma: labeling of monoclonal antibody cG250 with 131I, 90Y, 177Lu, or 186Re
-
Brouwers, A. H., van Eerd, J. E., Frielink, C., Oosterwijk, E., Oyen, W. J., Corstens, F. H., et al. (2004). Optimization of radioimmunotherapy of renal cell carcinoma: labeling of monoclonal antibody cG250 with 131I, 90Y, 177Lu, or 186Re. J. Nucl. Med. 45, 327-337
-
(2004)
J. Nucl. Med
, vol.45
, pp. 327-337
-
-
Brouwers, A.H.1
van Eerd, J.E.2
Frielink, C.3
Oosterwijk, E.4
Oyen, W.J.5
Corstens, F.H.6
-
17
-
-
84891930215
-
Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity
-
Casazza, A., Laoui, D., Wenes, M., Rizzolio, S., Bassani, N., Mambretti, M., et al. (2013). Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity. Cancer Cell 24, 695-709. doi: 10.1016/j.ccr.2013.11.007
-
(2013)
Cancer Cell
, vol.24
, pp. 695-709
-
-
Casazza, A.1
Laoui, D.2
Wenes, M.3
Rizzolio, S.4
Bassani, N.5
Mambretti, M.6
-
18
-
-
84944534047
-
Carving out its niche: a role for carbonic anhydrase IX in pre-metastatic niche development
-
Chafe, S. C., and Dedhar, S. (2015). Carving out its niche: a role for carbonic anhydrase IX in pre-metastatic niche development. Oncoimmunology 4:e1048955. doi: 10.1080/2162402X.2015.1048955
-
(2015)
Oncoimmunology
, vol.4
-
-
Chafe, S.C.1
Dedhar, S.2
-
19
-
-
84937512463
-
Carbonic anhydrase IX promotes myeloid-derived suppressor cell mobilization and establishment of a metastatic niche by stimulating G-CSF production
-
Chafe, S. C., Lou, Y., Sceneay, J., Vallejo, M., Hamilton, M. J., McDonald, P. C., et al. (2015). Carbonic anhydrase IX promotes myeloid-derived suppressor cell mobilization and establishment of a metastatic niche by stimulating G-CSF production. Cancer Res. 75, 996-1008. doi: 10.1158/0008-5472.CAN-14-3000
-
(2015)
Cancer Res
, vol.75
, pp. 996-1008
-
-
Chafe, S.C.1
Lou, Y.2
Sceneay, J.3
Vallejo, M.4
Hamilton, M.J.5
McDonald, P.C.6
-
20
-
-
84935025716
-
Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo
-
Chang, D. K., Moniz, R. J., Xu, Z., Sun, J., Signoretti, S., Zhu, Q., et al. (2015). Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo. Mol. Cancer 14, 119. doi: 10.1186/s12943-015-0384-3
-
(2015)
Mol. Cancer
, vol.14
, pp. 119
-
-
Chang, D.K.1
Moniz, R.J.2
Xu, Z.3
Sun, J.4
Signoretti, S.5
Zhu, Q.6
-
21
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche, J., Ilc, K., Laferrière, J., Trottier, E., Dayan, F., Mazure, N. M., et al. (2009). Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res. 69, 358-368. doi: 10.1158/0008-5472.CAN-08-2470
-
(2009)
Cancer Res
, vol.69
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferrière, J.3
Trottier, E.4
Dayan, F.5
Mazure, N.M.6
-
22
-
-
84857407549
-
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
-
Conley, S. J., Gheordunescu, E., Kakarala, P., Newman, B., Korkaya, H., Heath, A. N., et al. (2012). Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia. Proc. Natl. Acad. Sci. U.S.A. 109, 2784-2789. doi: 10.1073/pnas.1018866109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 2784-2789
-
-
Conley, S.J.1
Gheordunescu, E.2
Kakarala, P.3
Newman, B.4
Korkaya, H.5
Heath, A.N.6
-
23
-
-
78149330949
-
HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
Corzo, C. A., Condamine, T., Lu, L., Cotter, M. J., Youn, J. I., Cheng, P., et al. (2010). HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J. Exp. Med. 207, 2439-2453. doi: 10.1084/jem.20100587
-
(2010)
J. Exp. Med
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
Cotter, M.J.4
Youn, J.I.5
Cheng, P.6
-
24
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel, T. J., Wei, S., Dong, H., Alvarez, X., Cheng, P., Mottram, P., et al. (2003). Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat. Med. 9, 562-567. doi: 10.1038/nm863
-
(2003)
Nat. Med
, vol.9
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
25
-
-
84873727788
-
Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity
-
Currie, M. J., Beardsley, B. E., Harris, G. C., Gunningham, S. P., Dachs, G. U., Dijkstra, B., et al. (2013). Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity. Hum. Pathol. 44, 402-411. doi: 10.1016/j.humpath.2012.06.004
-
(2013)
Hum. Pathol
, vol.44
, pp. 402-411
-
-
Currie, M.J.1
Beardsley, B.E.2
Harris, G.C.3
Gunningham, S.P.4
Dachs, G.U.5
Dijkstra, B.6
-
26
-
-
84891705036
-
pH sensing and regulation in cancer
-
Damaghi, M., Wojtkowiak, J. W., and Gillies, R. J. (2013). pH sensing and regulation in cancer. Front. Physiol. 4:370. doi: 10.3389/fphys.2013.00370
-
(2013)
Front. Physiol
, vol.4
, pp. 370
-
-
Damaghi, M.1
Wojtkowiak, J.W.2
Gillies, R.J.3
-
27
-
-
84945460646
-
Local hyperthermia combined with radiotherapy and-/or chemotherapy: recent advances and promises for the future
-
Datta, N. R., Ordóñez, S. G., Gaipl, U. S., Paulides, M. M., Crezee, H., Gellermann, J., et al. (2015). Local hyperthermia combined with radiotherapy and-/or chemotherapy: recent advances and promises for the future. Cancer Treat. Rev. 41, 742-753. doi: 10.1016/j.ctrv.2015.05.009
-
(2015)
Cancer Treat. Rev
, vol.41
, pp. 742-753
-
-
Datta, N.R.1
Ordóñez, S.G.2
Gaipl, U.S.3
Paulides, M.M.4
Crezee, H.5
Gellermann, J.6
-
28
-
-
34548083337
-
A phase I multiple dose, dose escalation study of cG250 monoclonal antibody in patients with advanced renal cell carcinoma
-
Davis, I. D., Wiseman, G. A., Lee, F. T., Gansen, D. N., Hopkins, W., Papenfuss, A. T., et al. (2007). A phase I multiple dose, dose escalation study of cG250 monoclonal antibody in patients with advanced renal cell carcinoma. Cancer Immun. 7, 13
-
(2007)
Cancer Immun
, vol.7
, pp. 13
-
-
Davis, I.D.1
Wiseman, G.A.2
Lee, F.T.3
Gansen, D.N.4
Hopkins, W.5
Papenfuss, A.T.6
-
29
-
-
79959944026
-
Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
-
De Bock, K., Mazzone, M., and Carmeliet, P. (2011). Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? Nat. Rev. Clin. Oncol. 8, 393-404. doi: 10.1038/nrclinonc.2011.83
-
(2011)
Nat. Rev. Clin. Oncol
, vol.8
, pp. 393-404
-
-
De Bock, K.1
Mazzone, M.2
Carmeliet, P.3
-
30
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
DeNardo, D. G., Brennan, D. J., Rexhepaj, E., Ruffell, B., Shiao, S. L., Madden, S. F., et al. (2011). Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov. 1, 54-67. doi: 10.1158/2159-8274.CD-10-0028
-
(2011)
Cancer Discov
, vol.1
, pp. 54-67
-
-
DeNardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
-
31
-
-
84867660436
-
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
-
De Saedeleer, C. J., Copetti, T., Porporato, P. E., Verrax, J., Feron, O., and Sonveaux, P. (2012). Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells. PLoS ONE 7:e46571. doi: 10.1371/journal.pone.0046571
-
(2012)
PLoS ONE
, vol.7
-
-
De Saedeleer, C.J.1
Copetti, T.2
Porporato, P.E.3
Verrax, J.4
Feron, O.5
Sonveaux, P.6
-
32
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
Diaz-Montero, C. M., Salem, M. L., Nishimura, M. I., Garrett-Mayer, E., Cole, D. J., and Montero, A. J. (2009). Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol. Immunother. 58, 49-59. doi: 10.1007/s00262-008-0523-4
-
(2009)
Cancer Immunol. Immunother
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
33
-
-
77957350018
-
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
-
Doedens, A. L., Stockmann, C., Rubinstein, M. P., Liao, D., Zhang, N., DeNardo, D. G., et al. (2010). Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res. 70, 7465-7475. doi: 10.1158/0008-5472.CAN-10-1439
-
(2010)
Cancer Res
, vol.70
, pp. 7465-7475
-
-
Doedens, A.L.1
Stockmann, C.2
Rubinstein, M.P.3
Liao, D.4
Zhang, N.5
DeNardo, D.G.6
-
34
-
-
84883514161
-
Targeting lactate metabolism for cancer therapeutics
-
Doherty, J. R., and Cleveland, J. L. (2013). Targeting lactate metabolism for cancer therapeutics. J. Clin. Invest. 123, 3685-3692. doi: 10.1172/JCI69741
-
(2013)
J. Clin. Invest
, vol.123
, pp. 3685-3692
-
-
Doherty, J.R.1
Cleveland, J.L.2
-
35
-
-
18544363923
-
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
-
Dong, H., Strome, S. E., Salomao, D. R., Tamura, H., Hirano, F., Flies, D. B., et al. (2002). Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8, 793-800. doi: 10.1038/nm0902-1039c
-
(2002)
Nat. Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
36
-
-
84906282434
-
Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome
-
Doyen, J., Trastour, C., Ettore, F., Peyrottes, I., Toussant, N., Gal, J., et al. (2014). Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome. Biochem. Biophys. Res. Commun. 451, 54-61. doi: 10.1016/j.bbrc.2014.07.050
-
(2014)
Biochem. Biophys. Res. Commun
, vol.451
, pp. 54-61
-
-
Doyen, J.1
Trastour, C.2
Ettore, F.3
Peyrottes, I.4
Toussant, N.5
Gal, J.6
-
37
-
-
39849102836
-
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
-
Du, R., Lu, K. V., Petritsch, C., Liu, P., Ganss, R., Passegué, E., et al. (2008). HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 13, 206-220. doi: 10.1016/j.ccr.2008.01.034
-
(2008)
Cancer Cell
, vol.13
, pp. 206-220
-
-
Du, R.1
Lu, K.V.2
Petritsch, C.3
Liu, P.4
Ganss, R.5
Passegué, E.6
-
38
-
-
84887019683
-
Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs
-
Dubois, L., Peeters, S. G., van Kuijk, S. J., Yaromina, A., Lieuwes, N. G., Saraya, R., et al. (2013). Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs. Radiother. Oncol. 108, 523-528. doi: 10.1016/j.radonc.2013.06.018
-
(2013)
Radiother. Oncol
, vol.108
, pp. 523-528
-
-
Dubois, L.1
Peeters, S.G.2
van Kuijk, S.J.3
Yaromina, A.4
Lieuwes, N.G.5
Saraya, R.6
-
39
-
-
79960359073
-
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
-
Dubois, L., Peeters, S., Lieuwes, N. G., Geusens, N., Thiry, A., Wigfield, S., et al. (2011). Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation. Radiother. Oncol. 99, 424-431. doi: 10.1016/j.radonc.2011.05.045
-
(2011)
Radiother. Oncol
, vol.99
, pp. 424-431
-
-
Dubois, L.1
Peeters, S.2
Lieuwes, N.G.3
Geusens, N.4
Thiry, A.5
Wigfield, S.6
-
40
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos, J. M., Lee, C. R., Cruz-Munoz, W., Bjarnason, G. A., Christensen, J. G., and Kerbel, R. S. (2009). Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239. doi: 10.1016/j.ccr.2009.01.021
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
41
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler, J. T., Bennewith, K. L., Cox, T. R., Lang, G., Bird, D., Koong, A., et al. (2009). Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 15, 35-44. doi: 10.1016/j.ccr.2008.11.012
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
-
42
-
-
84874886049
-
Acidity generated by the tumor microenvironment drives local invasion
-
Estrella, V., Chen, T., Lloyd, M., Wojtkowiak, J., Cornnell, H. H., Ibrahim-Hashim, A., et al. (2013). Acidity generated by the tumor microenvironment drives local invasion. Cancer Res. 73, 1524-1535. doi: 10.1158/0008-5472.CAN-12-2796
-
(2013)
Cancer Res
, vol.73
, pp. 1524-1535
-
-
Estrella, V.1
Chen, T.2
Lloyd, M.3
Wojtkowiak, J.4
Cornnell, H.H.5
Ibrahim-Hashim, A.6
-
43
-
-
84860507700
-
T-regulatory cells: key players in tumor immune escape and angiogenesis
-
Facciabene, A., Motz, G. T., and Coukos, G. (2012). T-regulatory cells: key players in tumor immune escape and angiogenesis. Cancer Res. 72, 2162-2171. doi: 10.1158/0008-5472.CAN-11-3687
-
(2012)
Cancer Res
, vol.72
, pp. 2162-2171
-
-
Facciabene, A.1
Motz, G.T.2
Coukos, G.3
-
44
-
-
79960393113
-
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells
-
Facciabene, A., Peng, X., Hagemann, I. S., Balint, K., Barchetti, A., Wang, L. P., et al. (2011). Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature 475, 226-230. doi: 10.1038/nature10169
-
(2011)
Nature
, vol.475
, pp. 226-230
-
-
Facciabene, A.1
Peng, X.2
Hagemann, I.S.3
Balint, K.4
Barchetti, A.5
Wang, L.P.6
-
45
-
-
84901215262
-
The cellular and molecular origin of tumor-associated macrophages
-
Franklin, R. A., Liao, W., Sarkar, A., Kim, M. V., Bivona, M. R., Liu, K., et al. (2014). The cellular and molecular origin of tumor-associated macrophages. Science 344, 921-925. doi: 10.1126/science.1252510
-
(2014)
Science
, vol.344
, pp. 921-925
-
-
Franklin, R.A.1
Liao, W.2
Sarkar, A.3
Kim, M.V.4
Bivona, M.R.5
Liu, K.6
-
46
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I., and Nagaraj, S. (2009). Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174. doi: 10.1038/nri2506
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
47
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
Gabrilovich, D. I., Ostrand-Rosenberg, S., and Bronte, V. (2012). Coordinated regulation of myeloid cells by tumours. Nat. Rev. Immunol. 12, 253-268. doi: 10.1038/nri3175
-
(2012)
Nat. Rev. Immunol
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
48
-
-
84945969574
-
carbonic anhydrase activity monitored in vivo by hyperpolarized 13C-magnetic resonance spectroscopy demonstrates its importance for ph regulation in tumors
-
Gallagher, F. A., Sladen, H., Kettunen, M. I., Serrao, E. M., Rodrigues, T. B., Wright, A., et al. (2015). carbonic anhydrase activity monitored in vivo by hyperpolarized 13C-magnetic resonance spectroscopy demonstrates its importance for ph regulation in tumors. Cancer Res. 75, 4109-4118. doi: 10.1158/0008-5472.CAN-15-0857
-
(2015)
Cancer Res
, vol.75
, pp. 4109-4118
-
-
Gallagher, F.A.1
Sladen, H.2
Kettunen, M.I.3
Serrao, E.M.4
Rodrigues, T.B.5
Wright, A.6
-
49
-
-
37549013776
-
A microenvironmental model of carcinogenesis
-
Gatenby, R. A., and Gillies, R. J. (2008). A microenvironmental model of carcinogenesis. Nat. Rev. Cancer 8, 56-61. doi: 10.1038/nrc2255
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 56-61
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
50
-
-
84862290784
-
Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts
-
Gieling, R. G., Babur, M., Mamnani, L., Burrows, N., Telfer, B. A., Carta, F., et al. (2012). Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. J. Med. Chem. 55, 5591-5600. doi: 10.1021/jm300529u
-
(2012)
J. Med. Chem
, vol.55
, pp. 5591-5600
-
-
Gieling, R.G.1
Babur, M.2
Mamnani, L.3
Burrows, N.4
Telfer, B.A.5
Carta, F.6
-
51
-
-
84926669244
-
Metabolism and its sequelae in cancer evolution and therapy
-
Gillies, R. J., and Gatenby, R. A. (2015). Metabolism and its sequelae in cancer evolution and therapy. Cancer J. 21, 88-96. doi: 10.1097/PPO.0000000000000102
-
(2015)
Cancer J
, vol.21
, pp. 88-96
-
-
Gillies, R.J.1
Gatenby, R.A.2
-
52
-
-
46749121459
-
Causes and consequences of increased glucose metabolism of cancers
-
Gillies, R. J., Robey, I., and Gatenby, R. A. (2008). Causes and consequences of increased glucose metabolism of cancers. J. Nucl. Med. 49(Suppl. 2), 24S-42S. doi: 10.1016/s1359-6349(08)71425-3
-
(2008)
J. Nucl. Med
, vol.49
, pp. 24S-42S
-
-
Gillies, R.J.1
Robey, I.2
Gatenby, R.A.3
-
53
-
-
84862757952
-
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work
-
Gillies, R. J., Verduzco, D., and Gatenby, R. A. (2012). Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat. Rev. Cancer 12, 487-493. doi: 10.1038/nrc3298
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 487-493
-
-
Gillies, R.J.1
Verduzco, D.2
Gatenby, R.A.3
-
54
-
-
84873129546
-
CTLA-4 blockade in tumor models: an overview of preclinical and translational research
-
Grosso, J. F., and Jure-Kunkel, M. N. (2013). CTLA-4 blockade in tumor models: an overview of preclinical and translational research. Cancer Immun. 13, 5
-
(2013)
Cancer Immun
, vol.13
, pp. 5
-
-
Grosso, J.F.1
Jure-Kunkel, M.N.2
-
55
-
-
84937829481
-
Combined Trabectedin and anti-PD1 antibody produces a synergistic antitumor effect in a murine model of ovarian cancer
-
Guo, Z., Wang, H., Meng, F., Li, J., and Zhang, S. (2015). Combined Trabectedin and anti-PD1 antibody produces a synergistic antitumor effect in a murine model of ovarian cancer. J. Transl. Med. 13, 247. doi: 10.1186/s12967-015-0613-y
-
(2015)
J. Transl. Med
, vol.13
, pp. 247
-
-
Guo, Z.1
Wang, H.2
Meng, F.3
Li, J.4
Zhang, S.5
-
56
-
-
84893092415
-
Monocarboxylic acid transport
-
Halestrap, A. P. (2013). Monocarboxylic acid transport. Compr. Physiol. 3, 1611-1643. doi: 10.1002/cphy.c130008
-
(2013)
Compr. Physiol
, vol.3
, pp. 1611-1643
-
-
Halestrap, A.P.1
-
57
-
-
84858590826
-
Accessories to the crime: functions of cells recruited to the tumor microenvironment
-
Hanahan, D., and Coussens, L. M. (2012). Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322. doi: 10.1016/j.ccr.2012.02.022
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
58
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674. doi: 10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
59
-
-
84941784087
-
Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2hi macrophage-derived VEGFA
-
Harney, A. S., Arwert, E. N., Entenberg, D., Wang, Y., Guo, P., Qian, B. Z., et al. (2015). Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2hi macrophage-derived VEGFA. Cancer Discov. 5, 932-943. doi: 10.1158/2159-8290.CD-15-0012
-
(2015)
Cancer Discov
, vol.5
, pp. 932-943
-
-
Harney, A.S.1
Arwert, E.N.2
Entenberg, D.3
Wang, Y.4
Guo, P.5
Qian, B.Z.6
-
60
-
-
84958120328
-
Metabolic heterogeneity in human lung tumors
-
Hensley, C. T., Faubert, B., Yuan, Q., Lev-Cohain, N., Jin, E., Kim, J., et al. (2016). Metabolic heterogeneity in human lung tumors. Cell 164, 681-694. doi: 10.1016/j.cell.2015.12.034
-
(2016)
Cell
, vol.164
, pp. 681-694
-
-
Hensley, C.T.1
Faubert, B.2
Yuan, Q.3
Lev-Cohain, N.4
Jin, E.5
Kim, J.6
-
61
-
-
84901334642
-
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
-
Highfill, S. L., Cui, Y., Giles, A. J., Smith, J. P., Zhang, H., Morse, E., et al. (2014). Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. Sci. Transl. Med. 6:237ra267. doi: 10.1126/scitranslmed.3007974
-
(2014)
Sci. Transl. Med
, vol.6
, pp. 237ra267
-
-
Highfill, S.L.1
Cui, Y.2
Giles, A.J.3
Smith, J.P.4
Zhang, H.5
Morse, E.6
-
62
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F. S., O'Day, S. J., McDermott, D. F., Weber, R. W., Sosman, J. A., Haanen, J. B., et al. (2010). Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723. doi: 10.1056/NEJMoa1003466
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
63
-
-
84859385707
-
Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma
-
Hu, Y. L., DeLay, M., Jahangiri, A., Molinaro, A. M., Rose, S. D., Carbonell, W. S., et al. (2012). Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res. 72, 1773-1783. doi: 10.1158/0008-5472.CAN-11-3831
-
(2012)
Cancer Res
, vol.72
, pp. 1773-1783
-
-
Hu, Y.L.1
DeLay, M.2
Jahangiri, A.3
Molinaro, A.M.4
Rose, S.D.5
Carbonell, W.S.6
-
64
-
-
84925262623
-
Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma
-
Hu-Lieskovan, S., Mok, S., Homet Moreno, B., Tsoi, J., Robert, L., Goedert, L., et al. (2015). Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma. Sci. Transl. Med. 7:279ra241. doi: 10.1126/scitranslmed.aaa4691
-
(2015)
Sci. Transl. Med
, vol.7
-
-
Hu-Lieskovan, S.1
Mok, S.2
Homet Moreno, B.3
Tsoi, J.4
Robert, L.5
Goedert, L.6
-
65
-
-
84912096468
-
Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia
-
Jain, R. K. (2014). Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell 26, 605-622. doi: 10.1016/j.ccell.2014.10.006
-
(2014)
Cancer Cell
, vol.26
, pp. 605-622
-
-
Jain, R.K.1
-
66
-
-
84928771999
-
T cell exclusion, immune privilege, and the tumor microenvironment
-
Joyce, J. A., and Fearon, D. T. (2015). T cell exclusion, immune privilege, and the tumor microenvironment. Science 348, 74-80. doi: 10.1126/science.aaa6204
-
(2015)
Science
, vol.348
, pp. 74-80
-
-
Joyce, J.A.1
Fearon, D.T.2
-
67
-
-
84884368877
-
Influence of tumour micro-environment heterogeneity on therapeutic response
-
Junttila, M. R., and de Sauvage, F. J. (2013). Influence of tumour micro-environment heterogeneity on therapeutic response. Nature 501, 346-354. doi: 10.1038/nature12626
-
(2013)
Nature
, vol.501
, pp. 346-354
-
-
Junttila, M.R.1
de Sauvage, F.J.2
-
68
-
-
84877728919
-
The emerging 'hallmarks' of metabolic reprogramming and immune evasion: distinct or linked?
-
Kareva, I., and Hahnfeldt, P. (2013). The emerging 'hallmarks' of metabolic reprogramming and immune evasion: distinct or linked? Cancer Res. 73, 2737-2742. doi: 10.1158/0008-5472.can-12-3696
-
(2013)
Cancer Res
, vol.73
, pp. 2737-2742
-
-
Kareva, I.1
Hahnfeldt, P.2
-
69
-
-
84955171378
-
Estrogen and progesterone differentially regulate carbonic anhydrase II, III, IX, XII, and XIII in ovariectomized rat uteri
-
Karim, K., Giribabu, N., Muniandy, S., and Salleh, N. (2016). Estrogen and progesterone differentially regulate carbonic anhydrase II, III, IX, XII, and XIII in ovariectomized rat uteri. Syst. Biol. Reprod. Med. 62, 57-68. doi: 10.3109/19396368.2015.1112699
-
(2016)
Syst. Biol. Reprod. Med
, vol.62
, pp. 57-68
-
-
Karim, K.1
Giribabu, N.2
Muniandy, S.3
Salleh, N.4
-
70
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel, R. S. (2008). Tumor angiogenesis. N. Engl. J. Med. 358, 2039-2049. doi: 10.1056/NEJMra0706596
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
71
-
-
84905994658
-
Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells
-
Kim, K., Skora, A. D., Li, Z., Liu, Q., Tam, A. J., Blosser, R. L., et al. (2014). Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells. Proc. Natl. Acad. Sci. U.S.A. 111, 11774-11779. doi: 10.1073/pnas.1410626111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 11774-11779
-
-
Kim, K.1
Skora, A.D.2
Li, Z.3
Liu, Q.4
Tam, A.J.5
Blosser, R.L.6
-
72
-
-
84868207640
-
Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1alpha
-
Kim, Y. J., Lee, H. J., Kim, T. M., Eisinger-Mathason, T. S., Zhang, A. Y., Schmidt, B., et al. (2013). Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1alpha. Int. J. Cancer 132, 29-41. doi: 10.1002/ijc.27666
-
(2013)
Int. J. Cancer
, vol.132
, pp. 29-41
-
-
Kim, Y.J.1
Lee, H.J.2
Kim, T.M.3
Eisinger-Mathason, T.S.4
Zhang, A.Y.5
Schmidt, B.6
-
73
-
-
84898627356
-
A small-molecule drug conjugate for the treatment of carbonic anhydrase IX expressing tumors
-
Krall, N., Pretto, F., Decurtins, W., Bernardes, G. J., Supuran, C. T., and Neri, D. (2014). A small-molecule drug conjugate for the treatment of carbonic anhydrase IX expressing tumors. Angew. Chem. Int. Ed Engl. 53, 4231-4235. doi: 10.1002/anie.201310709
-
(2014)
Angew. Chem. Int. Ed Engl
, vol.53
, pp. 4231-4235
-
-
Krall, N.1
Pretto, F.2
Decurtins, W.3
Bernardes, G.J.4
Supuran, C.T.5
Neri, D.6
-
74
-
-
44449147036
-
Tumor cell metabolism: cancer's Achilles' heel
-
Kroemer, G., and Pouyssegur, J. (2008). Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13, 472-482. doi: 10.1016/j.ccr.2008.05.005
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
75
-
-
84906874906
-
Ado-trastuzumab Emtansine (T-DM1): an antibody-drug conjugate (ADC) for HER2-positive breast cancer
-
Lambert, J. M., and Chari, R. V. (2014). Ado-trastuzumab Emtansine (T-DM1): an antibody-drug conjugate (ADC) for HER2-positive breast cancer. J. Med. Chem. 57, 6949-6964. doi: 10.1021/jm500766w
-
(2014)
J. Med. Chem
, vol.57
, pp. 6949-6964
-
-
Lambert, J.M.1
Chari, R.V.2
-
76
-
-
84892747845
-
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population
-
Laoui, D., Van Overmeire, E., Di Conza, G., Aldeni, C., Keirsse, J., Morias, Y., et al. (2014). Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population. Cancer Res. 74, 24-30. doi: 10.1158/0008-5472.CAN-13-1196
-
(2014)
Cancer Res
, vol.74
, pp. 24-30
-
-
Laoui, D.1
Van Overmeire, E.2
Di Conza, G.3
Aldeni, C.4
Keirsse, J.5
Morias, Y.6
-
77
-
-
84939242207
-
Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition
-
Ledaki, I., McIntyre, A., Wigfield, S., Buffa, F., McGowan, S., Baban, D., et al. (2015). Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. Oncotarget 6, 19413-19427. doi: 10.18632/oncotarget.4989
-
(2015)
Oncotarget
, vol.6
, pp. 19413-19427
-
-
Ledaki, I.1
McIntyre, A.2
Wigfield, S.3
Buffa, F.4
McGowan, S.5
Baban, D.6
-
78
-
-
80053640489
-
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
-
Le Floch, R., Chiche, J., Marchiq, I., Naiken, T., Ilc, K., Murray, C. M., et al. (2011). CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors. Proc. Natl. Acad. Sci. U.S.A. 108, 16663-16668. doi: 10.1073/pnas.1106123108
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 16663-16668
-
-
Le Floch, R.1
Chiche, J.2
Marchiq, I.3
Naiken, T.4
Ilc, K.5
Murray, C.M.6
-
79
-
-
70450223507
-
Generating specificity and diversity in the transcriptional response to hypoxia
-
Lendahl, U., Lee, K. L., Yang, H., and Poellinger, L. (2009). Generating specificity and diversity in the transcriptional response to hypoxia. Nat. Rev. Genet. 10, 821-832. doi: 10.1038/nrg2665
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 821-832
-
-
Lendahl, U.1
Lee, K.L.2
Yang, H.3
Poellinger, L.4
-
80
-
-
84887098421
-
Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
-
Lock, F. E., McDonald, P. C., Lou, Y., Serrano, I., Chafe, S. C., Ostlund, C., et al. (2013). Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche. Oncogene 32, 5210-5219. doi: 10.1038/onc.2012.550
-
(2013)
Oncogene
, vol.32
, pp. 5210-5219
-
-
Lock, F.E.1
McDonald, P.C.2
Lou, Y.3
Serrano, I.4
Chafe, S.C.5
Ostlund, C.6
-
81
-
-
79955490807
-
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
-
Lou, Y., McDonald, P. C., Oloumi, A., Chia, S., Ostlund, C., Ahmadi, A., et al. (2011). Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res. 71, 3364-3376. doi: 10.1158/0008-5472.CAN-10-4261
-
(2011)
Cancer Res
, vol.71
, pp. 3364-3376
-
-
Lou, Y.1
McDonald, P.C.2
Oloumi, A.3
Chia, S.4
Ostlund, C.5
Ahmadi, A.6
-
82
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
Lu, H., Forbes, R. A., and Verma, A. (2002). Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J. Biol. Chem. 277, 23111-23115. doi: 10.1074/jbc.M202487200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 23111-23115
-
-
Lu, H.1
Forbes, R.A.2
Verma, A.3
-
83
-
-
84939811814
-
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
-
Lu, H., Samanta, D., Xiang, L., Zhang, H., Hu, H., Chen, I., et al. (2015). Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype. Proc. Natl. Acad. Sci. U.S.A. 112, E4600-E4609. doi: 10.1073/pnas.1513433112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. E4600-E4609
-
-
Lu, H.1
Samanta, D.2
Xiang, L.3
Zhang, H.4
Hu, H.5
Chen, I.6
-
84
-
-
84938350452
-
Combination cancer immunotherapy and new immunomodulatory targets
-
Mahoney, K. M., Rennert, P. D., and Freeman, G. J. (2015). Combination cancer immunotherapy and new immunomodulatory targets. Nat. Rev. Drug Discov. 14, 561-584. doi: 10.1038/nrd4591
-
(2015)
Nat. Rev. Drug Discov
, vol.14
, pp. 561-584
-
-
Mahoney, K.M.1
Rennert, P.D.2
Freeman, G.J.3
-
85
-
-
84959164423
-
Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H symporters
-
Marchiq, I., and Pouysségur, J. (2015). Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H symporters. J. Mol. Med. (Berl). 94, 155-171. doi: 10.1007/s00109-015-1307-x
-
(2015)
J. Mol. Med. (Berl)
, vol.94
, pp. 155-171
-
-
Marchiq, I.1
Pouysségur, J.2
-
86
-
-
84899771418
-
Carbonic Anhydrase IX (CAIX) as a mediator of hypoxia-induced stress response in cancer cells
-
McDonald, P. C., and Dedhar, S. (2014). Carbonic Anhydrase IX (CAIX) as a mediator of hypoxia-induced stress response in cancer cells. Subcell. Biochem. 75, 255-269. doi: 10.1007/978-94-007-7359-2_13
-
(2014)
Subcell. Biochem
, vol.75
, pp. 255-269
-
-
McDonald, P.C.1
Dedhar, S.2
-
87
-
-
84859870939
-
Recent developments in targeting carbonic anhydrase IX for cancer therapeutics
-
McDonald, P. C., Winum, J. Y., Supuran, C. T., and Dedhar, S. (2012). Recent developments in targeting carbonic anhydrase IX for cancer therapeutics. Oncotarget 3, 84-97. doi: 10.18632/oncotarget.422
-
(2012)
Oncotarget
, vol.3
, pp. 84-97
-
-
McDonald, P.C.1
Winum, J.Y.2
Supuran, C.T.3
Dedhar, S.4
-
88
-
-
84926166792
-
Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality
-
McIntyre, A., and Harris, A. L. (2015). Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality. EMBO Mol. Med. 7, 368-379. doi: 10.15252/emmm.201404271
-
(2015)
EMBO Mol. Med
, vol.7
, pp. 368-379
-
-
McIntyre, A.1
Harris, A.L.2
-
89
-
-
84861762712
-
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy
-
McIntyre, A., Patiar, S., Wigfield, S., Li, J. L., Ledaki, I., Turley, H., et al. (2012). Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clin. Cancer Res. 18, 3100-3111. doi: 10.1158/1078-0432.CCR-11-1877
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 3100-3111
-
-
McIntyre, A.1
Patiar, S.2
Wigfield, S.3
Li, J.L.4
Ledaki, I.5
Turley, H.6
-
90
-
-
84939121706
-
Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy
-
Messmer, M. N., Netherby, C. S., Banik, D., and Abrams, S. I. (2015). Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy. Cancer Immunol. Immunother. 64, 1-13. doi: 10.1007/s00262-014-1639-3
-
(2015)
Cancer Immunol. Immunother
, vol.64
, pp. 1-13
-
-
Messmer, M.N.1
Netherby, C.S.2
Banik, D.3
Abrams, S.I.4
-
91
-
-
79951983770
-
Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials
-
Miles, D., Harbeck, N., Escudier, B., Hurwitz, H., Saltz, L., Van Cutsem, E., et al. (2011). Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials. J. Clin. Oncol. 29, 83-88. doi: 10.1200/JCO.2010.30.2794
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 83-88
-
-
Miles, D.1
Harbeck, N.2
Escudier, B.3
Hurwitz, H.4
Saltz, L.5
Van Cutsem, E.6
-
92
-
-
84891831968
-
Sunitinib objective response in metastatic renal cell carcinoma: analysis of 1059 patients treated on clinical trials
-
Molina, A. M., Lin, X., Korytowsky, B., Matczak, E., Lechuga, M. J., Wiltshire, R., et al. (2014). Sunitinib objective response in metastatic renal cell carcinoma: analysis of 1059 patients treated on clinical trials. Eur. J. Cancer 50, 351-358. doi: 10.1016/j.ejca.2013.08.021
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 351-358
-
-
Molina, A.M.1
Lin, X.2
Korytowsky, B.3
Matczak, E.4
Lechuga, M.J.5
Wiltshire, R.6
-
93
-
-
78650580513
-
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
-
Moon, E. J., Sonveaux, P., Porporato, P. E., Danhier, P., Gallez, B., Batinic-Haberle, I., et al. (2010). NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. Proc. Natl. Acad. Sci. U.S.A. 107, 20477-20482. doi: 10.1073/pnas.1006646107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 20477-20482
-
-
Moon, E.J.1
Sonveaux, P.2
Porporato, P.E.3
Danhier, P.4
Gallez, B.5
Batinic-Haberle, I.6
-
94
-
-
84880757177
-
Deciphering and reversing tumor immune suppression
-
Motz, G. T., and Coukos, G. (2013). Deciphering and reversing tumor immune suppression. Immunity 39, 61-73. doi: 10.1016/j.immuni.2013.07.005
-
(2013)
Immunity
, vol.39
, pp. 61-73
-
-
Motz, G.T.1
Coukos, G.2
-
95
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes
-
Movahedi, K., Laoui, D., Gysemans, C., Baeten, M., Stangé, G., Van den Bossche, J., et al. (2010). Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 70, 5728-5739. doi: 10.1158/0008-5472.CAN-09-4672
-
(2010)
Cancer Res
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
Laoui, D.2
Gysemans, C.3
Baeten, M.4
Stangé, G.5
Van den Bossche, J.6
-
96
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
Murdoch, C., Giannoudis, A., and Lewis, C. E. (2004). Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 104, 2224-2234. doi: 10.1182/blood-2004-03-1109
-
(2004)
Blood
, vol.104
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
97
-
-
84971602476
-
Phase 2 study of lutetium 177-labeled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma
-
[Epub ahead of print]
-
Muselaers, C. H. J., Boers-Sonderen, M. J., van Oostenbrugge, T. J., Boerman, O. C., Desar, I. M. E., Stillebroer, A. B., et al. (2015). Phase 2 study of lutetium 177-labeled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma. Eur. Urol. doi: 10.1016/j.eururo.2015.11.033. [Epub ahead of print]
-
(2015)
Eur. Urol
-
-
Muselaers, C.H.J.1
Boers-Sonderen, M.J.2
van Oostenbrugge, T.J.3
Boerman, O.C.4
Desar, I.M.E.5
Stillebroer, A.B.6
-
98
-
-
80053563164
-
Interfering with pH regulation in tumours as a therapeutic strategy
-
Neri, D., and Supuran, C. T. (2011). Interfering with pH regulation in tumours as a therapeutic strategy. Nat. Rev. Drug Discov. 10, 767-777. doi: 10.1038/nrd3554
-
(2011)
Nat. Rev. Drug Discov
, vol.10
, pp. 767-777
-
-
Neri, D.1
Supuran, C.T.2
-
99
-
-
84942919454
-
A threshold level of intratumor CD8+ T-cell PD1 expression dictates therapeutic response to anti-PD1
-
Ngiow, S. F., Young, A., Jacquelot, N., Yamazaki, T., Enot, D., Zitvogel, L., et al. (2015). A threshold level of intratumor CD8+ T-cell PD1 expression dictates therapeutic response to anti-PD1. Cancer Res. 75, 3800-3811. doi: 10.1158/0008-5472.CAN-15-1082
-
(2015)
Cancer Res
, vol.75
, pp. 3800-3811
-
-
Ngiow, S.F.1
Young, A.2
Jacquelot, N.3
Yamazaki, T.4
Enot, D.5
Zitvogel, L.6
-
100
-
-
84899753178
-
PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
-
Noman, M. Z., Desantis, G., Janji, B., Hasmim, M., Karray, S., Dessen, P., et al. (2014). PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J. Exp. Med. 211, 781-790. doi: 10.1084/jem.20131916
-
(2014)
J. Exp. Med
, vol.211
, pp. 781-790
-
-
Noman, M.Z.1
Desantis, G.2
Janji, B.3
Hasmim, M.4
Karray, S.5
Dessen, P.6
-
101
-
-
84904406680
-
Tumor-associated macrophages: from mechanisms to therapy
-
Noy, R., and Pollard, J. W. (2014). Tumor-associated macrophages: from mechanisms to therapy. Immunity 41, 49-61. doi: 10.1016/j.immuni.2014.06.010
-
(2014)
Immunity
, vol.41
, pp. 49-61
-
-
Noy, R.1
Pollard, J.W.2
-
102
-
-
38849201787
-
Carbonic anhydrase IX/G250/MN: a molecule too good to be true?
-
Oosterwijk, E. (2008). Carbonic anhydrase IX/G250/MN: a molecule too good to be true? BJU Int. 101, 527-528. doi: 10.1111/j.1464-410x.2007.07431.x
-
(2008)
BJU Int
, vol.101
, pp. 527-528
-
-
Oosterwijk, E.1
-
103
-
-
84878454886
-
Application of monoclonal antibody G250 recognizing carbonic anhydrase IX in renal cell carcinoma
-
Oosterwijk-Wakka, J. C., Boerman, O. C., Mulders, P. F., and Oosterwijk, E. (2013). Application of monoclonal antibody G250 recognizing carbonic anhydrase IX in renal cell carcinoma. Int. J. Mol. Sci. 14, 11402-11423. doi: 10.3390/ijms140611402
-
(2013)
Int. J. Mol. Sci
, vol.14
, pp. 11402-11423
-
-
Oosterwijk-Wakka, J.C.1
Boerman, O.C.2
Mulders, P.F.3
Oosterwijk, E.4
-
104
-
-
79952808077
-
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis
-
Pacchiano, F., Carta, F., McDonald, P. C., Lou, Y., Vullo, D., Scozzafava, A., et al. (2011). Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis. J. Med. Chem. 54, 1896-1902. doi: 10.1021/jm101541x
-
(2011)
J. Med. Chem
, vol.54
, pp. 1896-1902
-
-
Pacchiano, F.1
Carta, F.2
McDonald, P.C.3
Lou, Y.4
Vullo, D.5
Scozzafava, A.6
-
105
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Pàez-Ribes, M., Allen, E., Hudock, J., Takeda, T., Okuyama, H., Viñals, F., et al. (2009). Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231. doi: 10.1016/j.ccr.2009.01.027
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Pàez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Viñals, F.6
-
106
-
-
84938657323
-
Potential proinvasive or metastatic effects of preclinical antiangiogenic therapy are prevented by concurrent chemotherapy
-
Paez-Ribes, M., Man, S., Xu, P., and Kerbel, R. S. (2015). Potential proinvasive or metastatic effects of preclinical antiangiogenic therapy are prevented by concurrent chemotherapy. Clin. Cancer Res. 21, 5488-5498. doi: 10.1158/1078-0432.CCR-15-0915
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 5488-5498
-
-
Paez-Ribes, M.1
Man, S.2
Xu, P.3
Kerbel, R.S.4
-
107
-
-
84908141221
-
HIF transcription factors, inflammation, and immunity
-
Palazon, A., Goldrath, A. W., Nizet, V., and Johnson, R. S. (2014). HIF transcription factors, inflammation, and immunity. Immunity 41, 518-528. doi: 10.1016/j.immuni.2014.09.008
-
(2014)
Immunity
, vol.41
, pp. 518-528
-
-
Palazon, A.1
Goldrath, A.W.2
Nizet, V.3
Johnson, R.S.4
-
108
-
-
84880721353
-
Dendritic-cell-based therapeutic cancer vaccines
-
Palucka, K., and Banchereau, J. (2013). Dendritic-cell-based therapeutic cancer vaccines. Immunity 39, 38-48. doi: 10.1016/j.immuni.2013.07.004
-
(2013)
Immunity
, vol.39
, pp. 38-48
-
-
Palucka, K.1
Banchereau, J.2
-
109
-
-
84872861339
-
Peroxisome proliferator activated receptor-alpha/hypoxia inducible Factor-1alpha interplay sustains carbonic anhydrase IX and apoliprotein e expression in breast cancer stem cells
-
Papi, A., Storci, G., Guarnieri, T., De Carolis, S., Bertoni, S., Avenia, N., et al. (2013). Peroxisome proliferator activated receptor-alpha/hypoxia inducible Factor-1alpha interplay sustains carbonic anhydrase IX and apoliprotein e expression in breast cancer stem cells. PLoS ONE 8:e54968. doi: 10.1371/journal.pone.0054968
-
(2013)
PLoS ONE
, vol.8
-
-
Papi, A.1
Storci, G.2
Guarnieri, T.3
De Carolis, S.4
Bertoni, S.5
Avenia, N.6
-
110
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll, D. M. (2012). The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252-264. doi: 10.1038/nrc3239
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
111
-
-
84883182637
-
Disrupting proton dynamics and energy metabolism for cancer therapy
-
Parks, S. K., Chiche, J., and Pouyssegur, J. (2013). Disrupting proton dynamics and energy metabolism for cancer therapy. Nat. Rev. Cancer 13, 611-623. doi: 10.1038/nrc3579
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 611-623
-
-
Parks, S.K.1
Chiche, J.2
Pouyssegur, J.3
-
112
-
-
84958119923
-
Hypoxia optimises tumour growth by controlling nutrient import and acidic metabolite export
-
Parks, S. K., Cormerais, Y., Marchiq, I., and Pouysségur, J. (2015). Hypoxia optimises tumour growth by controlling nutrient import and acidic metabolite export. Mol. Aspects Med. 47-48, 3-14. doi: 10.1016/j.mam.2015.12.001
-
(2015)
Mol. Aspects Med
, vol.47-48
, pp. 3-14
-
-
Parks, S.K.1
Cormerais, Y.2
Marchiq, I.3
Pouysségur, J.4
-
113
-
-
84923193781
-
Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use
-
Pastorek, J., and Pastorekova, S. (2015). Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use. Semin. Cancer Biol. 31, 52-64. doi: 10.1016/j.semcancer.2014.08.002
-
(2015)
Semin. Cancer Biol
, vol.31
, pp. 52-64
-
-
Pastorek, J.1
Pastorekova, S.2
-
114
-
-
84955326448
-
The emerging hallmarks of cancer metabolism
-
Pavlova, N. N., and Thompson, C. B. (2016). The emerging hallmarks of cancer metabolism. Cell Metab. 23, 27-47. doi: 10.1016/j.cmet.2015.12.006
-
(2016)
Cell Metab
, vol.23
, pp. 27-47
-
-
Pavlova, N.N.1
Thompson, C.B.2
-
115
-
-
84926646150
-
Common responses of tumors and wounds to hypoxia
-
Payen, V. L., Brisson, L., Dewhirst, M. W., and Sonveaux, P. (2015a). Common responses of tumors and wounds to hypoxia. Cancer J. 21, 75-87. doi: 10.1097/PPO.0000000000000098
-
(2015)
Cancer J
, vol.21
, pp. 75-87
-
-
Payen, V.L.1
Brisson, L.2
Dewhirst, M.W.3
Sonveaux, P.4
-
116
-
-
84949521347
-
Metabolic changes associated with tumor metastasis, part 1, tumor pH, glycolysis and the pentose phosphate pathway
-
Payen, V. L., Porporato, P. E., Baselet, B., and Sonveaux, P. (2015b). Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway. Cell. Mol. Life Sci. 73, 1333-1348. doi: 10.1007/s00018-015-2098-5
-
(2015)
Cell. Mol. Life Sci
, vol.73
, pp. 1333-1348
-
-
Payen, V.L.1
Porporato, P.E.2
Baselet, B.3
Sonveaux, P.4
-
117
-
-
84863116661
-
Therapeutic mechanism and efficacy of the antibody drug-conjugate BAY 79-4620 targeting human carbonic anhydrase 9
-
Petrul, H. M., Schatz, C. A., Kopitz, C. C., Adnane, L., McCabe, T. J., Trail, P., et al. (2011). Therapeutic mechanism and efficacy of the antibody drug-conjugate BAY 79-4620 targeting human carbonic anhydrase 9. Mol. Cancer Ther. 11, 340-349. doi: 10.1158/1535-7163.mct-11-0523
-
(2011)
Mol. Cancer Ther
, vol.11
, pp. 340-349
-
-
Petrul, H.M.1
Schatz, C.A.2
Kopitz, C.C.3
Adnane, L.4
McCabe, T.J.5
Trail, P.6
-
118
-
-
84896701206
-
Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer
-
Polanski, R., Hodgkinson, C. L., Fusi, A., Nonaka, D., Priest, L., Kelly, P., et al. (2014). Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. Clin. Cancer Res. 20, 926-937. doi: 10.1158/1078-0432.CCR-13-2270
-
(2014)
Clin. Cancer Res
, vol.20
, pp. 926-937
-
-
Polanski, R.1
Hodgkinson, C.L.2
Fusi, A.3
Nonaka, D.4
Priest, L.5
Kelly, P.6
-
119
-
-
84943143633
-
In vivo loss of function screening reveals carbonic anhydrase IX as a key modulator of tumor initiating potential in primary pancreatic tumors
-
Pore, N., Jalla, S., Liu, Z., Higgs, B., Sorio, C., Scarpa, A., et al. (2015). In vivo loss of function screening reveals carbonic anhydrase IX as a key modulator of tumor initiating potential in primary pancreatic tumors. Neoplasia 17, 473-480. doi: 10.1016/j.neo.2015.05.001
-
(2015)
Neoplasia
, vol.17
, pp. 473-480
-
-
Pore, N.1
Jalla, S.2
Liu, Z.3
Higgs, B.4
Sorio, C.5
Scarpa, A.6
-
120
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouysségur, J., Dayan, F., and Mazure, N. M. (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441, 437-443. doi: 10.1038/nature04871
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouysségur, J.1
Dayan, F.2
Mazure, N.M.3
-
121
-
-
84868011381
-
Function of carbonic anhydrase IX in glioblastoma multiforme
-
Proescholdt, M. A., Merrill, M. J., Stoerr, E. M., Lohmeier, A., Pohl, F., and Brawanski, A. (2012). Function of carbonic anhydrase IX in glioblastoma multiforme. Neurooncology 14, 1357-1366. doi: 10.1093/neuonc/nos216
-
(2012)
Neurooncology
, vol.14
, pp. 1357-1366
-
-
Proescholdt, M.A.1
Merrill, M.J.2
Stoerr, E.M.3
Lohmeier, A.4
Pohl, F.5
Brawanski, A.6
-
122
-
-
84887444879
-
Microenvironmental regulation of tumor progression and metastasis
-
Quail, D. F., and Joyce, J. A. (2013). Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 19, 1423-1437. doi: 10.1038/nm.3394
-
(2013)
Nat. Med
, vol.19
, pp. 1423-1437
-
-
Quail, D.F.1
Joyce, J.A.2
-
123
-
-
84887954229
-
Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates
-
Rami, M., Dubois, L., Parvathaneni, N. K., Alterio, V., van Kuijk, S. J., Monti, S. M., et al. (2013). Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates. J. Med. Chem. 56, 8512-8520. doi: 10.1021/jm4009532
-
(2013)
J. Med. Chem
, vol.56
, pp. 8512-8520
-
-
Rami, M.1
Dubois, L.2
Parvathaneni, N.K.3
Alterio, V.4
van Kuijk, S.J.5
Monti, S.M.6
-
124
-
-
67651166780
-
Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
-
Rapisarda, A., Hollingshead, M., Uranchimeg, B., Bonomi, C. A., Borgel, S. D., Carter, J. P., et al. (2009). Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition. Mol. Cancer Ther. 8, 1867-1877. doi: 10.1158/1535-7163.MCT-09-0274
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 1867-1877
-
-
Rapisarda, A.1
Hollingshead, M.2
Uranchimeg, B.3
Bonomi, C.A.4
Borgel, S.D.5
Carter, J.P.6
-
125
-
-
84863422466
-
Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
-
Rapisarda, A., and Melillo, G. (2012). Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia. Nat. Rev. Clin. Oncol. 9, 378-390. doi: 10.1038/nrclinonc.2012.64
-
(2012)
Nat. Rev. Clin. Oncol
, vol.9
, pp. 378-390
-
-
Rapisarda, A.1
Melillo, G.2
-
126
-
-
84930736841
-
Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer
-
Rohan, T. E., Xue, X., Lin, H. M., D'Alfonso, T. M., Ginter, P. S., Oktay, M. H., et al. (2014). Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer. J. Nat. Cancer Inst. 106:dju136. doi: 10.1093/jnci/dju136
-
(2014)
J. Nat. Cancer Inst
, vol.106
-
-
Rohan, T.E.1
Xue, X.2
Lin, H.M.3
D'Alfonso, T.M.4
Ginter, P.S.5
Oktay, M.H.6
-
127
-
-
84918530536
-
Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells
-
Samanta, D., Gilkes, D. M., Chaturvedi, P., Xiang, L., and Semenza, G. L. (2014). Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc. Natl. Acad. Sci. U.S.A. 111, E5429-E5438. doi: 10.1073/pnas.1421438111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. E5429-E5438
-
-
Samanta, D.1
Gilkes, D.M.2
Chaturvedi, P.3
Xiang, L.4
Semenza, G.L.5
-
128
-
-
84865130953
-
Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche
-
Sceneay, J., Chow, M. T., Chen, A., Halse, H. M., Wong, C. S., Andrews, D. M., et al. (2012). Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. Cancer Res. 72, 3906-3911. doi: 10.1158/0008-5472.CAN-11-3873
-
(2012)
Cancer Res
, vol.72
, pp. 3906-3911
-
-
Sceneay, J.1
Chow, M.T.2
Chen, A.3
Halse, H.M.4
Wong, C.S.5
Andrews, D.M.6
-
129
-
-
84871127292
-
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth
-
Schlecker, E., Stojanovic, A., Eisen, C., Quack, C., Falk, C. S., Umansky, V., et al. (2012). Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth. J. Immunol. 189, 5602-5611. doi: 10.4049/jimmunol.1201018
-
(2012)
J. Immunol
, vol.189
, pp. 5602-5611
-
-
Schlecker, E.1
Stojanovic, A.2
Eisen, C.3
Quack, C.4
Falk, C.S.5
Umansky, V.6
-
130
-
-
84858785688
-
Antibody therapy of cancer
-
Scott, A. M., Wolchok, J. D., and Old, L. J. (2012). Antibody therapy of cancer. Nat. Rev. Cancer 12, 278-287. doi: 10.1038/nrc3236
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 278-287
-
-
Scott, A.M.1
Wolchok, J.D.2
Old, L.J.3
-
131
-
-
84893522300
-
Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
-
Sedlakova, O., Svastova, E., Takacova, M., Kopacek, J., Pastorek, J., and Pastorekova, S. (2014). Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors. Front. Physiol. 4:400. doi: 10.3389/fphys.2013.00400
-
(2014)
Front. Physiol
, vol.4
, pp. 400
-
-
Sedlakova, O.1
Svastova, E.2
Takacova, M.3
Kopacek, J.4
Pastorek, J.5
Pastorekova, S.6
-
132
-
-
84878936788
-
Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells
-
Selby, M. J., Engelhardt, J. J., Quigley, M., Henning, K. A., Chen, T., Srinivasan, M., et al. (2013). Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells. Cancer Immunol Res 1, 32-42. doi: 10.1158/2326-6066.CIR-13-0013
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 32-42
-
-
Selby, M.J.1
Engelhardt, J.J.2
Quigley, M.3
Henning, K.A.4
Chen, T.5
Srinivasan, M.6
-
133
-
-
84897019542
-
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
-
Semenza, G. L. (2014). Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu. Rev. Pathol. 9, 47-71. doi: 10.1146/annurev-pathol-012513-104720
-
(2014)
Annu. Rev. Pathol
, vol.9
, pp. 47-71
-
-
Semenza, G.L.1
-
134
-
-
34547820876
-
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
-
Shojaei, F., Wu, X., Malik, A. K., Zhong, C., Baldwin, M. E., Schanz, S., et al. (2007). Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat. Biotechnol. 25, 911-920. doi: 10.1038/nbt1323
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 911-920
-
-
Shojaei, F.1
Wu, X.2
Malik, A.K.3
Zhong, C.4
Baldwin, M.E.5
Schanz, S.6
-
135
-
-
66149092730
-
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
-
Shojaei, F., Wu, X., Qu, X., Kowanetz, M., Yu, L., Tan, M., et al. (2009). G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc. Natl. Acad. Sci. U.S.A. 106, 6742-6747. doi: 10.1073/pnas.0902280106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 6742-6747
-
-
Shojaei, F.1
Wu, X.2
Qu, X.3
Kowanetz, M.4
Yu, L.5
Tan, M.6
-
136
-
-
78751650361
-
A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX(R)) and interferon-alpha-2a in metastatic renal cell carcinoma patients
-
Siebels, M., Rohrmann, K., Oberneder, R., Stahler, M., Haseke, N., Beck, J., et al. (2011). A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX(R)) and interferon-alpha-2a in metastatic renal cell carcinoma patients. World J. Urol. 29, 121-126. doi: 10.1007/s00345-010-0570-2
-
(2011)
World J. Urol
, vol.29
, pp. 121-126
-
-
Siebels, M.1
Rohrmann, K.2
Oberneder, R.3
Stahler, M.4
Haseke, N.5
Beck, J.6
-
137
-
-
49649105571
-
Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide
-
Siemens, D. R., Hu, N., Sheikhi, A. K., Chung, E., Frederiksen, L. J., Pross, H., et al. (2008). Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide. Cancer Res. 68, 4746-4753. doi: 10.1158/0008-5472.CAN-08-0054
-
(2008)
Cancer Res
, vol.68
, pp. 4746-4753
-
-
Siemens, D.R.1
Hu, N.2
Sheikhi, A.K.3
Chung, E.4
Frederiksen, L.J.5
Pross, H.6
-
138
-
-
57449097020
-
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
-
Sonveaux, P., Végran, F., Schroeder, T., Wergin, M. C., Verrax, J., Rabbani, Z. N., et al. (2008). Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J. Clin. Invest. 118, 3930-3942. doi: 10.1172/jci36843
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3930-3942
-
-
Sonveaux, P.1
Végran, F.2
Schroeder, T.3
Wergin, M.C.4
Verrax, J.5
Rabbani, Z.N.6
-
139
-
-
57649112725
-
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
-
Stockmann, C., Doedens, A., Weidemann, A., Zhang, N., Takeda, N., Greenberg, J. I., et al. (2008). Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature 456, 814-818. doi: 10.1038/nature07445
-
(2008)
Nature
, vol.456
, pp. 814-818
-
-
Stockmann, C.1
Doedens, A.2
Weidemann, A.3
Zhang, N.4
Takeda, N.5
Greenberg, J.I.6
-
140
-
-
84867818496
-
Inhibition of carbonic anhydrase IX as a novel anticancer mechanism
-
Supuran, C. T. (2012). Inhibition of carbonic anhydrase IX as a novel anticancer mechanism. World J. Clin. Oncol. 3, 98-103. doi: 10.5306/wjco.v3.i7.98
-
(2012)
World J. Clin. Oncol
, vol.3
, pp. 98-103
-
-
Supuran, C.T.1
-
141
-
-
0030017852
-
Anti-renal-cell carcinoma chimeric antibody G250 facilitates antibody-dependent cellular cytotoxicity with in vitro and in vivo interleukin-2-activated effectors
-
Surfus, J. E., Hank, J. A., Oosterwijk, E., Welt, S., Lindstrom, M. J., Albertini, M. R., et al. (1996). Anti-renal-cell carcinoma chimeric antibody G250 facilitates antibody-dependent cellular cytotoxicity with in vitro and in vivo interleukin-2-activated effectors. J. Immunother. Emphasis Tumor Immunol. 19, 184-191. doi: 10.1097/00002371-199605000-00003
-
(1996)
J. Immunother. Emphasis Tumor Immunol
, vol.19
, pp. 184-191
-
-
Surfus, J.E.1
Hank, J.A.2
Oosterwijk, E.3
Welt, S.4
Lindstrom, M.J.5
Albertini, M.R.6
-
142
-
-
84878782832
-
Carbonic anhydrase IX: a hypoxia-controlled 'catalyst' of cell migration
-
Svastova, E., and Pastorekova, S. (2013). Carbonic anhydrase IX: a hypoxia-controlled 'catalyst' of cell migration. Cell Adh. Migr. 7, 226-231. doi: 10.4161/cam.23257
-
(2013)
Cell Adh. Migr
, vol.7
, pp. 226-231
-
-
Svastova, E.1
Pastorekova, S.2
-
143
-
-
78650308850
-
New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
-
Swietach, P., Hulikova, A., Vaughan-Jones, R. D., and Harris, A. L. (2010). New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation. Oncogene 29, 6509-6521. doi: 10.1038/onc.2010.455
-
(2010)
Oncogene
, vol.29
, pp. 6509-6521
-
-
Swietach, P.1
Hulikova, A.2
Vaughan-Jones, R.D.3
Harris, A.L.4
-
144
-
-
84884556145
-
History of myeloid-derived suppressor cells
-
Talmadge, J. E., and Gabrilovich, D. I. (2013). History of myeloid-derived suppressor cells. Nat. Rev. Cancer 13, 739-752. doi: 10.1038/nrc3581
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 739-752
-
-
Talmadge, J.E.1
Gabrilovich, D.I.2
-
145
-
-
84928062583
-
Immune checkpoint blockade: a common denominator approach to cancer therapy
-
Topalian, S. L., Drake, C. G., and Pardoll, D. M. (2015). Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 27, 450-461. doi: 10.1016/j.ccell.2015.03.001
-
(2015)
Cancer Cell
, vol.27
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
146
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S. L., Hodi, F. S., Brahmer, J. R., Gettinger, S. N., Smith, D. C., McDermott, D. F., et al. (2012). Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454. doi: 10.1056/NEJMoa1200690
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
147
-
-
84055176334
-
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors
-
Touisni, N., Maresca, A., McDonald, P. C., Lou, Y., Scozzafava, A., Dedhar, S., et al. (2011). Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors. J. Med. Chem. 54, 8271-8277. doi: 10.1021/jm200983e
-
(2011)
J. Med. Chem
, vol.54
, pp. 8271-8277
-
-
Touisni, N.1
Maresca, A.2
McDonald, P.C.3
Lou, Y.4
Scozzafava, A.5
Dedhar, S.6
-
148
-
-
84954349409
-
Inhibition of carbonic anhydrase potentiates bevacizumab treatment in cholangiocarcinoma
-
[Epub ahead of print]
-
Vaeteewoottacharn, K., Kariya, R., Dana, P., Fujikawa, S., Matsuda, K., Ohkuma, K., et al. (2016). Inhibition of carbonic anhydrase potentiates bevacizumab treatment in cholangiocarcinoma. Tumour Biol. doi: 10.1007/s13277-016-4785-8. [Epub ahead of print]
-
(2016)
Tumour Biol
-
-
Vaeteewoottacharn, K.1
Kariya, R.2
Dana, P.3
Fujikawa, S.4
Matsuda, K.5
Ohkuma, K.6
-
149
-
-
84931271695
-
The great escape; the hallmarks of resistance to antiangiogenic therapy
-
van Beijnum, J. R., Nowak-Sliwinska, P., Huijbers, E. J., Thijssen, V. L., and Griffioen, A. W. (2015). The great escape; the hallmarks of resistance to antiangiogenic therapy. Pharmacol. Rev. 67, 441-461. doi: 10.1124/pr.114.010215
-
(2015)
Pharmacol. Rev
, vol.67
, pp. 441-461
-
-
van Beijnum, J.R.1
Nowak-Sliwinska, P.2
Huijbers, E.J.3
Thijssen, V.L.4
Griffioen, A.W.5
-
150
-
-
84944463700
-
Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models
-
Ward, C., Meehan, J., Mullen, P., Supuran, C., Dixon, J. M., Thomas, J. S., et al. (2015). Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. Oncotarget 6, 24856-24870. doi: 10.18632/oncotarget.4498
-
(2015)
Oncotarget
, vol.6
, pp. 24856-24870
-
-
Ward, C.1
Meehan, J.2
Mullen, P.3
Supuran, C.4
Dixon, J.M.5
Thomas, J.S.6
-
151
-
-
81155159685
-
Dysregulated pH: a perfect storm for cancer progression
-
Webb, B. A., Chimenti, M., Jacobson, M. P., and Barber, D. L. (2011). Dysregulated pH: a perfect storm for cancer progression. Nat. Rev. Cancer 11, 671-677. doi: 10.1038/nrc3110
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 671-677
-
-
Webb, B.A.1
Chimenti, M.2
Jacobson, M.P.3
Barber, D.L.4
-
152
-
-
84881232071
-
Recent molecular discoveries in angiogenesis and anti-angiogenic therapies in cancer
-
Welti, J., Loges, S., Dimmeler, S., and Carmeliet, P. (2013). Recent molecular discoveries in angiogenesis and anti-angiogenic therapies in cancer. J. Clin. Invest. 123, 3190-3200. doi: 10.1172/JCI70212
-
(2013)
J. Clin. Invest
, vol.123
, pp. 3190-3200
-
-
Welti, J.1
Loges, S.2
Dimmeler, S.3
Carmeliet, P.4
-
153
-
-
84991030573
-
Myeloid derived suppressor cells-a new therapeutic target in the treatment of cancer
-
Wesolowski, R., Markowitz, J., and Carson, W. E. III (2013). Myeloid derived suppressor cells-a new therapeutic target in the treatment of cancer. J. Immunother. Cancer 1, 10. doi: 10.1186/2051-1426-1-10
-
(2013)
J. Immunother. Cancer
, vol.1
, pp. 10
-
-
Wesolowski, R.1
Markowitz, J.2
Carson, W.E.3
-
154
-
-
84937837169
-
Molecular and cellular insights into T cell exhaustion
-
Wherry, E. J., and Kurachi, M. (2015). Molecular and cellular insights into T cell exhaustion. Nat. Rev. Immunol. 15, 486-499. doi: 10.1038/nri3862
-
(2015)
Nat. Rev. Immunol
, vol.15
, pp. 486-499
-
-
Wherry, E.J.1
Kurachi, M.2
-
155
-
-
84923169480
-
Targeting carbonic anhydrase IX with small organic ligands
-
Wichert, M., and Krall, N. (2015). Targeting carbonic anhydrase IX with small organic ligands. Curr. Opin. Chem. Biol. 26, 48-54. doi: 10.1016/j.cbpa.2015.02.005
-
(2015)
Curr. Opin. Chem. Biol
, vol.26
, pp. 48-54
-
-
Wichert, M.1
Krall, N.2
-
156
-
-
79957534572
-
Targeting hypoxia in cancer therapy
-
Wilson, W. R., and Hay, M. P. (2011). Targeting hypoxia in cancer therapy. Nat. Rev. Cancer 11, 393-410. doi: 10.1038/nrc3064
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 393-410
-
-
Wilson, W.R.1
Hay, M.P.2
-
157
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok, J. D., Kluger, H., Callahan, M. K., Postow, M. A., Rizvi, N. A., Lesokhin, A. M., et al. (2013). Nivolumab plus ipilimumab in advanced melanoma. N. Engl. J. Med. 369, 122-133. doi: 10.1056/NEJMoa1302369
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
-
158
-
-
80053645045
-
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
-
Wong, C. C., Gilkes, D. M., Zhang, H., Chen, J., Wei, H., Chaturvedi, P., et al. (2011). Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc. Natl. Acad. Sci. U.S.A. 108, 16369-16374. doi: 10.1073/pnas.1113483108
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 16369-16374
-
-
Wong, C.C.1
Gilkes, D.M.2
Zhang, H.3
Chen, J.4
Wei, H.5
Chaturvedi, P.6
-
159
-
-
77949716901
-
Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology
-
Xu, C., Lo, A., Yammanuru, A., Tallarico, A. S., Brady, K., Murakami, A., et al. (2010). Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology. PLoS ONE 5:e9625. doi: 10.1371/journal.pone.0009625
-
(2010)
PLoS ONE
, vol.5
-
-
Xu, C.1
Lo, A.2
Yammanuru, A.3
Tallarico, A.S.4
Brady, K.5
Murakami, A.6
-
160
-
-
84949255251
-
Estrogen receptor-alpha directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
-
Yang, J., AlTahan, A., Jones, D. T., Buffa, F. M., Bridges, E., Interiano, R. B., et al. (2015). Estrogen receptor-alpha directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer. Proc. Natl. Acad. Sci. U.S.A. 112, 15172-15177. doi: 10.1073/pnas.1422015112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. 15172-15177
-
-
Yang, J.1
AlTahan, A.2
Jones, D.T.3
Buffa, F.M.4
Bridges, E.5
Interiano, R.B.6
-
161
-
-
78649813619
-
Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain
-
Zatovicova, M., Jelenska, L., Hulikova, A., Csaderova, L., Ditte, Z., Ditte, P., et al. (2010). Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain. Curr. Pharm. Des. 16, 3255-3263. doi: 10.2174/138161210793429832
-
(2010)
Curr. Pharm. Des
, vol.16
, pp. 3255-3263
-
-
Zatovicova, M.1
Jelenska, L.2
Hulikova, A.3
Csaderova, L.4
Ditte, Z.5
Ditte, P.6
-
162
-
-
84907695899
-
Monoclonal antibody G250 targeting CA: binding specificity, internalization and therapeutic effects in a non-renal cancer model
-
Zatovicova, M., Jelenska, L., Hulikova, A., Ditte, P., Ditte, Z., Csaderova, L., et al. (2014). Monoclonal antibody G250 targeting CA: binding specificity, internalization and therapeutic effects in a non-renal cancer model. Int. J. Oncol. 45, 2455-2467. doi: 10.3892/ijo.2014.2658
-
(2014)
Int. J. Oncol
, vol.45
, pp. 2455-2467
-
-
Zatovicova, M.1
Jelenska, L.2
Hulikova, A.3
Ditte, P.4
Ditte, Z.5
Csaderova, L.6
-
163
-
-
33645286546
-
Regulatory T cells, tumour immunity and immunotherapy
-
Zou, W. (2006). Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol. 6, 295-307. doi: 10.1038/nri1806
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 295-307
-
-
Zou, W.1
|