Targeting tumor hypoxia: Suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors

Cancer Research

Volumn 71, Issue 9, 2011, Pages 3364-3376

  Lou, Yuanmei ^a   McDonald, Paul C ^a   Oloumi, Arusha ^a   Chia, Stephen ^a   Ostlund, Christina ^a   Ahmadi, Ardalan ^a   Kyle, Alastair ^a   Auf Dem Keller, Ulrich ^b   Leung, Samuel ^c   Huntsman, David ^a,c   Clarke, Blaise ^c,d   Sutherland, Brent W ^a   Waterhouse, Dawn ^a   Bally, Marcel ^a   Roskelley, Calvin ^b   Overall, Christopher M ^b   Minchinton, Andrew ^a   Pacchiano, Fabio ^e   Carta, Fabrizio ^e   Scozzafava, Andrea ^e   Touisni, Nadia ^f   Winum, Jean Yves ^f   Supuran, Claudiu T ^e   Dedhar, Shoukat ^a,b   more..

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Genetic Pathology Evaluation Centre   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

^e UNIVERSITY OF FLORENCE   (Italy)

^f UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CAI 17; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE IX INHIBITOR; CASPASE; COUMARIN DERIVATIVE; GC 204; GC 205; SHORT HAIRPIN RNA; SULFONAMIDE; TUMOR MARKER; U 104; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL DEATH; CELL PH; CONTROLLED STUDY; DRUG STRUCTURE; EXTRACELLULAR SPACE; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL;

ANIMALS; BREAST NEOPLASMS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CELL GROWTH PROCESSES; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; TUMOR MARKERS, BIOLOGICAL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79955490807     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-4261     Document Type: Article

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