Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia

Nature Reviews Clinical Oncology

Volumn 9, Issue 7, 2012, Pages 378-390

  Rapisarda, Annamaria ^a   Melillo, Giovanni ^b  

^a SAIC FREDERICK INC   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BORTEZOMIB; CABOZANTINIB; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CHEMOKINE RECEPTOR CXCR4; CISPLATIN; FLUOROURACIL; FOLINIC ACID; FORETINIB; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IRINOTECAN; OXALIPLATIN; PACLITAXEL; RAPAMYCIN; SCATTER FACTOR RECEPTOR; SORAFENIB; SU 10944; SUNITINIB; TOPOTECAN; UNCLASSIFIED DRUG; XL 999;

ADVANCED CANCER; ANTIANGIOGENIC THERAPY; ANTINEOPLASTIC ACTIVITY; BOLD SIGNAL; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER SURVIVAL; COLON CANCER; COLORECTAL CANCER; DNA DAMAGE; DNA REPAIR; DRUG EFFICACY; DRUG TREATMENT FAILURE; GASTROINTESTINAL STROMAL TUMOR; GLIOBLASTOMA; HUMAN; HYPOXIA; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; LIVER CELL CARCINOMA; LOW DRUG DOSE; LUNG NON SMALL CELL CANCER; MELANOMA; METASTASIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARY CANCER; OVERALL SURVIVAL; PANCREAS ISLET CELL TUMOR; PATIENT SELECTION; PH; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANOXIA; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 84863422466     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2012.64     Document Type: Review

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