메뉴 건너뛰기




Volumn 39, Issue 1, 2013, Pages 61-73

Deciphering and Reversing Tumor Immune Suppression

Author keywords

[No Author keywords available]

Indexed keywords

CANCER IMMUNOTHERAPY; CANCER LOCALIZATION; DENDRITIC CELL; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; LEUKOCYTE; PRIORITY JOURNAL; REVIEW; TUMOR CELL; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

EID: 84880757177     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2013.07.005     Document Type: Review
Times cited : (489)

References (181)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S., Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105:1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 4
    • 0033083191 scopus 로고    scopus 로고
    • Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth
    • Bagnato A., Salani D., Di Castro V., Wu-Wong J.R., Tecce R., Nicotra M.R., Venuti A., Natali P.G. Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. Cancer Res. 1999, 59:720-727.
    • (1999) Cancer Res. , vol.59 , pp. 720-727
    • Bagnato, A.1    Salani, D.2    Di Castro, V.3    Wu-Wong, J.R.4    Tecce, R.5    Nicotra, M.R.6    Venuti, A.7    Natali, P.G.8
  • 5
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat. Rev. Cancer 2009, 9:361-371.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 7
    • 55249095393 scopus 로고    scopus 로고
    • Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha
    • Ben-Shoshan J., Maysel-Auslender S., Mor A., Keren G., George J. Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur. J. Immunol. 2008, 38:2412-2418.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2412-2418
    • Ben-Shoshan, J.1    Maysel-Auslender, S.2    Mor, A.3    Keren, G.4    George, J.5
  • 9
    • 33847137354 scopus 로고    scopus 로고
    • Invivo imaging of cytotoxic Tcell infiltration and elimination of a solid tumor
    • Boissonnas A., Fetler L., Zeelenberg I.S., Hugues S., Amigorena S. Invivo imaging of cytotoxic Tcell infiltration and elimination of a solid tumor. J.Exp. Med. 2007, 204:345-356.
    • (2007) J.Exp. Med. , vol.204 , pp. 345-356
    • Boissonnas, A.1    Fetler, L.2    Zeelenberg, I.S.3    Hugues, S.4    Amigorena, S.5
  • 12
    • 33846482153 scopus 로고    scopus 로고
    • Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy
    • Bouzin C., Brouet A., De Vriese J., Dewever J., Feron O. Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy. J.Immunol. 2007, 178:1505-1511.
    • (2007) J.Immunol. , vol.178 , pp. 1505-1511
    • Bouzin, C.1    Brouet, A.2    De Vriese, J.3    Dewever, J.4    Feron, O.5
  • 14
    • 27144476792 scopus 로고    scopus 로고
    • A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation
    • Braun D., Longman R.S., Albert M.L. A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood 2005, 106:2375-2381.
    • (2005) Blood , vol.106 , pp. 2375-2381
    • Braun, D.1    Longman, R.S.2    Albert, M.L.3
  • 15
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) Tcells
    • Bronte V., Apolloni E., Cabrelle A., Ronca R., Serafini P., Zamboni P., Restifo N.P., Zanovello P. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) Tcells. Blood 2000, 96:3838-3846.
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6    Restifo, N.P.7    Zanovello, P.8
  • 17
    • 38449118049 scopus 로고    scopus 로고
    • Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred Tcells
    • Brown C.E., Vishwanath R.P., Aguilar B., Starr R., Najbauer J., Aboody K.S., Jensen M.C. Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred Tcells. J.Immunol. 2007, 179:3332-3341.
    • (2007) J.Immunol. , vol.179 , pp. 3332-3341
    • Brown, C.E.1    Vishwanath, R.P.2    Aguilar, B.3    Starr, R.4    Najbauer, J.5    Aboody, K.S.6    Jensen, M.C.7
  • 22
    • 0035056017 scopus 로고    scopus 로고
    • CTLA-4-mediated inhibition in regulation of Tcell responses: mechanisms and manipulation in tumor immunotherapy
    • Chambers C.A., Kuhns M.S., Egen J.G., Allison J.P. CTLA-4-mediated inhibition in regulation of Tcell responses: mechanisms and manipulation in tumor immunotherapy. Annu. Rev. Immunol. 2001, 19:565-594.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 565-594
    • Chambers, C.A.1    Kuhns, M.S.2    Egen, J.G.3    Allison, J.P.4
  • 23
    • 19444382439 scopus 로고    scopus 로고
    • Classical and nonclassical HLA class I antigen and NK Cell-activating ligand changes in malignant cells: current challenges and future directions
    • Chang C.C., Campoli M., Ferrone S. Classical and nonclassical HLA class I antigen and NK Cell-activating ligand changes in malignant cells: current challenges and future directions. Adv. Cancer Res. 2005, 93:189-234.
    • (2005) Adv. Cancer Res. , vol.93 , pp. 189-234
    • Chang, C.C.1    Campoli, M.2    Ferrone, S.3
  • 24
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive Tcells to CD4+CD25+ regulatory Tcells by TGF-beta induction of transcription factor Foxp3
    • Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., McGrady G., Wahl S.M. Conversion of peripheral CD4+CD25- naive Tcells to CD4+CD25+ regulatory Tcells by TGF-beta induction of transcription factor Foxp3. J.Exp. Med. 2003, 198:1875-1886.
    • (2003) J.Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 29
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory Tcells: more of the same or a division of labor?
    • Curotto de Lafaille M.A., Lafaille J.J. Natural and adaptive foxp3+ regulatory Tcells: more of the same or a division of labor?. Immunity 2009, 30:626-635.
    • (2009) Immunity , vol.30 , pp. 626-635
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2
  • 30
    • 0028128957 scopus 로고
    • Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation
    • Davenpeck K.L., Gauthier T.W., Lefer A.M. Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation. Gastroenterology 1994, 107:1050-1058.
    • (1994) Gastroenterology , vol.107 , pp. 1050-1058
    • Davenpeck, K.L.1    Gauthier, T.W.2    Lefer, A.M.3
  • 31
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R., Libby P., Peng H.B., Thannickal V.J., Rajavashisth T.B., Gimbrone M.A., Shin W.S., Liao J.K. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J.Clin. Invest. 1995, 96:60-68.
    • (1995) J.Clin. Invest. , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone, M.A.6    Shin, W.S.7    Liao, J.K.8
  • 37
    • 79955021759 scopus 로고    scopus 로고
    • Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ Tcell responses during the effector phase invivo
    • Dolfi D.V., Duttagupta P.A., Boesteanu A.C., Mueller Y.M., Oliai C.H., Borowski A.B., Katsikis P.D. Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ Tcell responses during the effector phase invivo. J.Immunol. 2011, 186:4599-4608.
    • (2011) J.Immunol. , vol.186 , pp. 4599-4608
    • Dolfi, D.V.1    Duttagupta, P.A.2    Boesteanu, A.C.3    Mueller, Y.M.4    Oliai, C.H.5    Borowski, A.B.6    Katsikis, P.D.7
  • 42
    • 84879104519 scopus 로고    scopus 로고
    • Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
    • Duraiswamy J., Kaluza K.M., Freeman G.J., Coukos G. Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors. Cancer Res. 2013, 73:3591-3603.
    • (2013) Cancer Res. , vol.73 , pp. 3591-3603
    • Duraiswamy, J.1    Kaluza, K.M.2    Freeman, G.J.3    Coukos, G.4
  • 43
    • 79953244361 scopus 로고    scopus 로고
    • Antiangiogenic therapy: impact on invasion, disease progression, and metastasis
    • Ebos J.M., Kerbel R.S. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011, 8:210-221.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 210-221
    • Ebos, J.M.1    Kerbel, R.S.2
  • 44
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: new insights into its biological function and use in tumor immunotherapy
    • Egen J.G., Kuhns M.S., Allison J.P. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 2002, 3:611-618.
    • (2002) Nat. Immunol. , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 48
    • 84860507700 scopus 로고    scopus 로고
    • T-regulatory cells: key players in tumor immune escape and angiogenesis
    • Facciabene A., Motz G.T., Coukos G. T-regulatory cells: key players in tumor immune escape and angiogenesis. Cancer Res. 2012, 72:2162-2171.
    • (2012) Cancer Res. , vol.72 , pp. 2162-2171
    • Facciabene, A.1    Motz, G.T.2    Coukos, G.3
  • 49
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory Tcells
    • Fontenot J.D., Rasmussen J.P., Gavin M.A., Rudensky A.Y. A function for interleukin 2 in Foxp3-expressing regulatory Tcells. Nat. Immunol. 2005, 6:1142-1151.
    • (2005) Nat. Immunol. , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 51
    • 34548125294 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
    • Fricke I., Mirza N., Dupont J., Lockhart C., Jackson A., Lee J.H., Sosman J.A., Gabrilovich D.I. Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin. Cancer Res. 2007, 13:4840-4848.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4840-4848
    • Fricke, I.1    Mirza, N.2    Dupont, J.3    Lockhart, C.4    Jackson, A.5    Lee, J.H.6    Sosman, J.A.7    Gabrilovich, D.I.8
  • 52
    • 65849194190 scopus 로고    scopus 로고
    • Expression and function of ETA and ETB receptors in SSc
    • Frommer K.W., Müller-Ladner U. Expression and function of ETA and ETB receptors in SSc. Rheumatology (Oxford) 2008, 47(Suppl 5):v27-v28.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.SUPPL 5
    • Frommer, K.W.1    Müller-Ladner, U.2
  • 54
    • 0031029637 scopus 로고    scopus 로고
    • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions
    • Fukumura D., Yuan F., Endo M., Jain R.K. Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. Am. J. Pathol. 1997, 150:713-725.
    • (1997) Am. J. Pathol. , vol.150 , pp. 713-725
    • Fukumura, D.1    Yuan, F.2    Endo, M.3    Jain, R.K.4
  • 55
    • 33745559710 scopus 로고    scopus 로고
    • The role of nitric oxide in tumour progression
    • Fukumura D., Kashiwagi S., Jain R.K. The role of nitric oxide in tumour progression. Nat. Rev. Cancer 2006, 6:521-534.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 521-534
    • Fukumura, D.1    Kashiwagi, S.2    Jain, R.K.3
  • 56
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 2004, 4:941-952.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 57
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich D.I., Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 2009, 9:162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 59
    • 0032741283 scopus 로고    scopus 로고
    • Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
    • Gabrilovich D.I., Ishida T., Nadaf S., Ohm J.E., Carbone D.P. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin. Cancer Res. 1999, 5:2963-2970.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2963-2970
    • Gabrilovich, D.I.1    Ishida, T.2    Nadaf, S.3    Ohm, J.E.4    Carbone, D.P.5
  • 65
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek D.C., Lu L.F., Quezada S.A., Sakaguchi S., Noelle R.J. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J.Immunol. 2005, 174:1783-1786.
    • (2005) J.Immunol. , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 67
    • 0029943319 scopus 로고    scopus 로고
    • Tumor angiogenesis is accompanied by a decreased inflammatory response of tumor-associated endothelium
    • Griffioen A.W., Damen C.A., Blijham G.H., Groenewegen G. Tumor angiogenesis is accompanied by a decreased inflammatory response of tumor-associated endothelium. Blood 1996, 88:667-673.
    • (1996) Blood , vol.88 , pp. 667-673
    • Griffioen, A.W.1    Damen, C.A.2    Blijham, G.H.3    Groenewegen, G.4
  • 68
    • 0030044629 scopus 로고    scopus 로고
    • Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors
    • Griffioen A.W., Damen C.A., Martinotti S., Blijham G.H., Groenewegen G. Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors. Cancer Res. 1996, 56:1111-1117.
    • (1996) Cancer Res. , vol.56 , pp. 1111-1117
    • Griffioen, A.W.1    Damen, C.A.2    Martinotti, S.3    Blijham, G.H.4    Groenewegen, G.5
  • 71
    • 80053156515 scopus 로고    scopus 로고
    • Dendritic cell and macrophage heterogeneity invivo
    • Hashimoto D., Miller J., Merad M. Dendritic cell and macrophage heterogeneity invivo. Immunity 2011, 35:323-335.
    • (2011) Immunity , vol.35 , pp. 323-335
    • Hashimoto, D.1    Miller, J.2    Merad, M.3
  • 72
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated Tcells and cyclooxygenase 2
    • Hernández G.L., Volpert O.V., Iñiguez M.A., Lorenzo E., Martínez-Martínez S., Grau R., Fresno M., Redondo J.M. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated Tcells and cyclooxygenase 2. J.Exp. Med. 2001, 193:607-620.
    • (2001) J.Exp. Med. , vol.193 , pp. 607-620
    • Hernández, G.L.1    Volpert, O.V.2    Iñiguez, M.A.3    Lorenzo, E.4    Martínez-Martínez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 75
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B., Pan P.Y., Li Q., Sato A.I., Levy D.E., Bromberg J., Divino C.M., Chen S.H. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 2006, 66:1123-1131.
    • (2006) Cancer Res. , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 76
    • 77949524521 scopus 로고    scopus 로고
    • Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion
    • Huang X., Bai X., Cao Y., Wu J., Huang M., Tang D., Tao S., Zhu T., Liu Y., Yang Y., et al. Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion. J.Exp. Med. 2010, 207:505-520.
    • (2010) J.Exp. Med. , vol.207 , pp. 505-520
    • Huang, X.1    Bai, X.2    Cao, Y.3    Wu, J.4    Huang, M.5    Tang, D.6    Tao, S.7    Zhu, T.8    Liu, Y.9    Yang, Y.10
  • 78
    • 84856021596 scopus 로고    scopus 로고
    • Prognostic significance of tumor-infiltrating Tcells in ovarian cancer: a meta-analysis
    • Hwang W.T., Adams S.F., Tahirovic E., Hagemann I.S., Coukos G. Prognostic significance of tumor-infiltrating Tcells in ovarian cancer: a meta-analysis. Gynecol. Oncol. 2012, 124:192-198.
    • (2012) Gynecol. Oncol. , vol.124 , pp. 192-198
    • Hwang, W.T.1    Adams, S.F.2    Tahirovic, E.3    Hagemann, I.S.4    Coukos, G.5
  • 80
    • 0032211082 scopus 로고    scopus 로고
    • Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors
    • Ishida T., Oyama T., Carbone D.P., Gabrilovich D.I. Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors. J.Immunol. 1998, 161:4842-4851.
    • (1998) J.Immunol. , vol.161 , pp. 4842-4851
    • Ishida, T.1    Oyama, T.2    Carbone, D.P.3    Gabrilovich, D.I.4
  • 81
    • 33745261751 scopus 로고    scopus 로고
    • Specific recruitment of CC chemokine receptor 4-positive regulatory Tcells in Hodgkin lymphoma fosters immune privilege
    • Ishida T., Ishii T., Inagaki A., Yano H., Komatsu H., Iida S., Inagaki H., Ueda R. Specific recruitment of CC chemokine receptor 4-positive regulatory Tcells in Hodgkin lymphoma fosters immune privilege. Cancer Res. 2006, 66:5716-5722.
    • (2006) Cancer Res. , vol.66 , pp. 5716-5722
    • Ishida, T.1    Ishii, T.2    Inagaki, A.3    Yano, H.4    Komatsu, H.5    Iida, S.6    Inagaki, H.7    Ueda, R.8
  • 82
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y., Ishida M., Tanaka Y., Okazaki T., Honjo T., Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. USA 2002, 99:12293-12297.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 83
    • 0031179646 scopus 로고    scopus 로고
    • IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kaliński P., Hilkens C.M., Snijders A., Snijdewint F.G., Kapsenberg M.L. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J.Immunol. 1997, 159:28-35.
    • (1997) J.Immunol. , vol.159 , pp. 28-35
    • Kaliński, P.1    Hilkens, C.M.2    Snijders, A.3    Snijdewint, F.G.4    Kapsenberg, M.L.5
  • 85
    • 79952281752 scopus 로고    scopus 로고
    • Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance
    • Kandalaft L.E., Motz G.T., Duraiswamy J., Coukos G. Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance. Cancer Metastasis Rev. 2011, 30:141-151.
    • (2011) Cancer Metastasis Rev. , vol.30 , pp. 141-151
    • Kandalaft, L.E.1    Motz, G.T.2    Duraiswamy, J.3    Coukos, G.4
  • 88
    • 34247476063 scopus 로고    scopus 로고
    • Potential functional role of plasmacytoid dendritic cells in cancer immunity
    • Kim R., Emi M., Tanabe K., Arihiro K. Potential functional role of plasmacytoid dendritic cells in cancer immunity. Immunology 2007, 121:149-157.
    • (2007) Immunology , vol.121 , pp. 149-157
    • Kim, R.1    Emi, M.2    Tanabe, K.3    Arihiro, K.4
  • 89
    • 84858257263 scopus 로고    scopus 로고
    • Dual targeting strategies with bispecific antibodies
    • Kontermann R. Dual targeting strategies with bispecific antibodies. mAbs 2012, 4:182-197.
    • (2012) mAbs , vol.4 , pp. 182-197
    • Kontermann, R.1
  • 91
    • 0025731835 scopus 로고
    • Nitric oxide: an endogenous modulator of leukocyte adhesion
    • Kubes P., Suzuki M., Granger D.N. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 1991, 88:4651-4655.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 92
    • 0033592924 scopus 로고    scopus 로고
    • Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
    • Kwon E.D., Foster B.A., Hurwitz A.A., Madias C., Allison J.P., Greenberg N.M., Burg M.B. Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy. Proc. Natl. Acad. Sci. USA 1999, 96:15074-15079.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 15074-15079
    • Kwon, E.D.1    Foster, B.A.2    Hurwitz, A.A.3    Madias, C.4    Allison, J.P.5    Greenberg, N.M.6    Burg, M.B.7
  • 94
    • 10044275221 scopus 로고    scopus 로고
    • Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization
    • LeCouter J., Zlot C., Tejada M., Peale F., Ferrara N. Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization. Proc. Natl. Acad. Sci. USA 2004, 101:16813-16818.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16813-16818
    • LeCouter, J.1    Zlot, C.2    Tejada, M.3    Peale, F.4    Ferrara, N.5
  • 96
    • 0037041028 scopus 로고    scopus 로고
    • Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells
    • Lin R., LeCouter J., Kowalski J., Ferrara N. Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells. J.Biol. Chem. 2002, 277:8724-8729.
    • (2002) J.Biol. Chem. , vol.277 , pp. 8724-8729
    • Lin, R.1    LeCouter, J.2    Kowalski, J.3    Ferrara, N.4
  • 97
    • 33847337912 scopus 로고    scopus 로고
    • Tumor evasion of the immune system by converting CD4+CD25- Tcells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta
    • Liu V.C., Wong L.Y., Jang T., Shah A.H., Park I., Yang X., Zhang Q., Lonning S., Teicher B.A., Lee C. Tumor evasion of the immune system by converting CD4+CD25- Tcells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J.Immunol. 2007, 178:2883-2892.
    • (2007) J.Immunol. , vol.178 , pp. 2883-2892
    • Liu, V.C.1    Wong, L.Y.2    Jang, T.3    Shah, A.H.4    Park, I.5    Yang, X.6    Zhang, Q.7    Lonning, S.8    Teicher, B.A.9    Lee, C.10
  • 98
    • 65949098671 scopus 로고    scopus 로고
    • Chapter 1. Isolation, identification, and production of posttranslationally modified chemokines
    • Loos T., Mortier A., Proost P. Chapter 1. Isolation, identification, and production of posttranslationally modified chemokines. Methods Enzymol. 2009, 461:3-29.
    • (2009) Methods Enzymol. , vol.461 , pp. 3-29
    • Loos, T.1    Mortier, A.2    Proost, P.3
  • 101
    • 13244273592 scopus 로고    scopus 로고
    • Contrasting frequencies of antitumor and anti-vaccine Tcells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen
    • Lurquin C., Lethé B., De Plaen E., Corbière V., Théate I., van Baren N., Coulie P.G., Boon T. Contrasting frequencies of antitumor and anti-vaccine Tcells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen. J.Exp. Med. 2005, 201:249-257.
    • (2005) J.Exp. Med. , vol.201 , pp. 249-257
    • Lurquin, C.1    Lethé, B.2    De Plaen, E.3    Corbière, V.4    Théate, I.5    van Baren, N.6    Coulie, P.G.7    Boon, T.8
  • 102
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
    • Lutz M.B., Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?. Trends Immunol. 2002, 23:445-449.
    • (2002) Trends Immunol. , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 106
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: the tolerogenic function of immature dendritic cells
    • Mahnke K., Schmitt E., Bonifaz L., Enk A.H., Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol. Cell Biol. 2002, 80:477-483.
    • (2002) Immunol. Cell Biol. , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 108
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance
    • Marincola F.M., Jaffee E.M., Hicklin D.J., Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv. Immunol. 2000, 74:181-273.
    • (2000) Adv. Immunol. , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 110
    • 0036785604 scopus 로고    scopus 로고
    • B7-H1 is expressed by human endothelial cells and suppresses Tcell cytokine synthesis
    • Mazanet M.M., Hughes C.C. B7-H1 is expressed by human endothelial cells and suppresses Tcell cytokine synthesis. J.Immunol. 2002, 169:3581-3588.
    • (2002) J.Immunol. , vol.169 , pp. 3581-3588
    • Mazanet, M.M.1    Hughes, C.C.2
  • 111
    • 36249026290 scopus 로고    scopus 로고
    • The ovarian endothelin network: an evolving story
    • Meidan R., Levy N. The ovarian endothelin network: an evolving story. Trends Endocrinol. Metab. 2007, 18:379-385.
    • (2007) Trends Endocrinol. Metab. , vol.18 , pp. 379-385
    • Meidan, R.1    Levy, N.2
  • 112
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: specialized and regulated antigen processing machines
    • Mellman I., Steinman R.M. Dendritic cells: specialized and regulated antigen processing machines. Cell 2001, 106:255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 113
    • 84861545489 scopus 로고    scopus 로고
    • Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
    • Mendler A.N., Hu B., Prinz P.U., Kreutz M., Gottfried E., Noessner E. Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation. Int. J. Cancer 2012, 131:633-640.
    • (2012) Int. J. Cancer , vol.131 , pp. 633-640
    • Mendler, A.N.1    Hu, B.2    Prinz, P.U.3    Kreutz, M.4    Gottfried, E.5    Noessner, E.6
  • 114
    • 0032535002 scopus 로고    scopus 로고
    • Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor
    • Menetrier-Caux C., Montmain G., Dieu M.C., Bain C., Favrot M.C., Caux C., Blay J.Y. Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. Blood 1998, 92:4778-4791.
    • (1998) Blood , vol.92 , pp. 4778-4791
    • Menetrier-Caux, C.1    Montmain, G.2    Dieu, M.C.3    Bain, C.4    Favrot, M.C.5    Caux, C.6    Blay, J.Y.7
  • 115
    • 14044275077 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway
    • Min J.K., Lee Y.M., Kim J.H., Kim Y.M., Kim S.W., Lee S.Y., Gho Y.S., Oh G.T., Kwon Y.G. Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway. Circ. Res. 2005, 96:300-307.
    • (2005) Circ. Res. , vol.96 , pp. 300-307
    • Min, J.K.1    Lee, Y.M.2    Kim, J.H.3    Kim, Y.M.4    Kim, S.W.5    Lee, S.Y.6    Gho, Y.S.7    Oh, G.T.8    Kwon, Y.G.9
  • 117
    • 80053159303 scopus 로고    scopus 로고
    • The parallel lives of angiogenesis and immunosuppression: cancer and other tales
    • Motz G.T., Coukos G. The parallel lives of angiogenesis and immunosuppression: cancer and other tales. Nat. Rev. Immunol. 2011, 11:702-711.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 702-711
    • Motz, G.T.1    Coukos, G.2
  • 118
    • 71849109766 scopus 로고    scopus 로고
    • Tumors induce the formation of suppressor endothelial cells invivo
    • Mulligan J.K., Young M.R. Tumors induce the formation of suppressor endothelial cells invivo. Cancer Immunol. Immunother 2010, 59:267-277.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 267-277
    • Mulligan, J.K.1    Young, M.R.2
  • 119
    • 67349139311 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions
    • Mulligan J.K., Day T.A., Gillespie M.B., Rosenzweig S.A., Young M.R. Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions. Hum. Immunol. 2009, 70:375-382.
    • (2009) Hum. Immunol. , vol.70 , pp. 375-382
    • Mulligan, J.K.1    Day, T.A.2    Gillespie, M.B.3    Rosenzweig, S.A.4    Young, M.R.5
  • 120
  • 121
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C., Muthana M., Coffelt S.B., Lewis C.E. The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 2008, 8:618-631.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 122
    • 77956599685 scopus 로고    scopus 로고
    • PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive Tcells
    • Muthuswamy R., Mueller-Berghaus J., Haberkorn U., Reinhart T.A., Schadendorf D., Kalinski P. PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive Tcells. Blood 2010, 116:1454-1459.
    • (2010) Blood , vol.116 , pp. 1454-1459
    • Muthuswamy, R.1    Mueller-Berghaus, J.2    Haberkorn, U.3    Reinhart, T.A.4    Schadendorf, D.5    Kalinski, P.6
  • 123
    • 84864834764 scopus 로고    scopus 로고
    • NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells
    • Muthuswamy R., Berk E., Junecko B.F., Zeh H.J., Zureikat A.H., Normolle D., Luong T.M., Reinhart T.A., Bartlett D.L., Kalinski P. NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells. Cancer Res. 2012, 72:3735-3743.
    • (2012) Cancer Res. , vol.72 , pp. 3735-3743
    • Muthuswamy, R.1    Berk, E.2    Junecko, B.F.3    Zeh, H.J.4    Zureikat, A.H.5    Normolle, D.6    Luong, T.M.7    Reinhart, T.A.8    Bartlett, D.L.9    Kalinski, P.10
  • 125
    • 0032529466 scopus 로고    scopus 로고
    • CD8+ Tcells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
    • Naito Y., Saito K., Shiiba K., Ohuchi A., Saigenji K., Nagura H., Ohtani H. CD8+ Tcells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res. 1998, 58:3491-3494.
    • (1998) Cancer Res. , vol.58 , pp. 3491-3494
    • Naito, Y.1    Saito, K.2    Shiiba, K.3    Ohuchi, A.4    Saigenji, K.5    Nagura, H.6    Ohtani, H.7
  • 128
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Network C.G.A. Comprehensive molecular portraits of human breast tumours. Nature 2012, 490:61-70. Cancer Genome Atlas Network.
    • (2012) Nature , vol.490 , pp. 61-70
    • Network, C.G.A.1
  • 131
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory Tcells induce cytokine deprivation-mediated apoptosis of effector CD4+ Tcells
    • Pandiyan P., Zheng L., Ishihara S., Reed J., Lenardo M.J. CD4+CD25+Foxp3+ regulatory Tcells induce cytokine deprivation-mediated apoptosis of effector CD4+ Tcells. Nat. Immunol. 2007, 8:1353-1362.
    • (2007) Nat. Immunol. , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 133
    • 0034660606 scopus 로고    scopus 로고
    • Endothelium-derived factors as paracrine mediators of prostate cancer progression
    • Pirtskhalaishvili G., Nelson J.B. Endothelium-derived factors as paracrine mediators of prostate cancer progression. Prostate 2000, 44:77-87.
    • (2000) Prostate , vol.44 , pp. 77-87
    • Pirtskhalaishvili, G.1    Nelson, J.B.2
  • 135
    • 34250166248 scopus 로고    scopus 로고
    • Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration
    • Proost P., Mortier A., Loos T., Vandercappellen J., Gouwy M., Ronsse I., Schutyser E., Put W., Parmentier M., Struyf S., Van Damme J. Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration. Blood 2007, 110:37-44.
    • (2007) Blood , vol.110 , pp. 37-44
    • Proost, P.1    Mortier, A.2    Loos, T.3    Vandercappellen, J.4    Gouwy, M.5    Ronsse, I.6    Schutyser, E.7    Put, W.8    Parmentier, M.9    Struyf, S.10    Van Damme, J.11
  • 137
    • 36248995916 scopus 로고    scopus 로고
    • Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory Tcells
    • Ren X., Ye F., Jiang Z., Chu Y., Xiong S., Wang Y. Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory Tcells. Cell Death Differ. 2007, 14:2076-2084.
    • (2007) Cell Death Differ. , vol.14 , pp. 2076-2084
    • Ren, X.1    Ye, F.2    Jiang, Z.3    Chu, Y.4    Xiong, S.5    Wang, Y.6
  • 138
    • 37249048334 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma
    • Riesenberg R., Weiler C., Spring O., Eder M., Buchner A., Popp T., Castro M., Kammerer R., Takikawa O., Hatz R.A., et al. Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. Clin. Cancer Res. 2007, 13:6993-7002.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6993-7002
    • Riesenberg, R.1    Weiler, C.2    Spring, O.3    Eder, M.4    Buchner, A.5    Popp, T.6    Castro, M.7    Kammerer, R.8    Takikawa, O.9    Hatz, R.A.10
  • 139
    • 65349118810 scopus 로고    scopus 로고
    • PD-1 signaling in primary Tcells
    • Riley J.L. PD-1 signaling in primary Tcells. Immunol. Rev. 2009, 229:114-125.
    • (2009) Immunol. Rev. , vol.229 , pp. 114-125
    • Riley, J.L.1
  • 142
    • 20644439105 scopus 로고    scopus 로고
    • MHC class Ib molecules bridge innate and acquired immunity
    • Rodgers J.R., Cook R.G. MHC class Ib molecules bridge innate and acquired immunity. Nat. Rev. Immunol. 2005, 5:459-471.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 459-471
    • Rodgers, J.R.1    Cook, R.G.2
  • 144
    • 70449580340 scopus 로고    scopus 로고
    • Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer
    • Roland C.L., Lynn K.D., Toombs J.E., Dineen S.P., Udugamasooriya D.G., Brekken R.A. Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer. PLoS ONE 2009, 4:e7669.
    • (2009) PLoS ONE , vol.4
    • Roland, C.L.1    Lynn, K.D.2    Toombs, J.E.3    Dineen, S.P.4    Udugamasooriya, D.G.5    Brekken, R.A.6
  • 146
    • 0024433980 scopus 로고
    • A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression, and biological activity
    • Saida K., Mitsui Y., Ishida N. A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression, and biological activity. J.Biol. Chem. 1989, 264:14613-14616.
    • (1989) J.Biol. Chem. , vol.264 , pp. 14613-14616
    • Saida, K.1    Mitsui, Y.2    Ishida, N.3
  • 147
    • 84863899032 scopus 로고    scopus 로고
    • The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences
    • Sainz-Perez A., Lim A., Lemercier B., Leclerc C. The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences. Cancer Res. 2012, 72:3557-3569.
    • (2012) Cancer Res. , vol.72 , pp. 3557-3569
    • Sainz-Perez, A.1    Lim, A.2    Lemercier, B.3    Leclerc, C.4
  • 148
    • 0033724661 scopus 로고    scopus 로고
    • Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization invivo
    • Salani D., Taraboletti G., Rosanò L., Di Castro V., Borsotti P., Giavazzi R., Bagnato A. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization invivo. Am. J. Pathol. 2000, 157:1703-1711.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1703-1711
    • Salani, D.1    Taraboletti, G.2    Rosanò, L.3    Di Castro, V.4    Borsotti, P.5    Giavazzi, R.6    Bagnato, A.7
  • 149
    • 0031594280 scopus 로고    scopus 로고
    • TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation
    • Sata M., Walsh K. TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nat. Med. 1998, 4:415-420.
    • (1998) Nat. Med. , vol.4 , pp. 415-420
    • Sata, M.1    Walsh, K.2
  • 150
    • 84867911410 scopus 로고    scopus 로고
    • Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells
    • Sawant A., Hensel J.A., Chanda D., Harris B.A., Siegal G.P., Maheshwari A., Ponnazhagan S. Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J.Immunol. 2012, 189:4258-4265.
    • (2012) J.Immunol. , vol.189 , pp. 4258-4265
    • Sawant, A.1    Hensel, J.A.2    Chanda, D.3    Harris, B.A.4    Siegal, G.P.5    Maheshwari, A.6    Ponnazhagan, S.7
  • 151
    • 0037388367 scopus 로고    scopus 로고
    • TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted Tcells specific for autologous tumor in late-stage ovarian cancer patients
    • Schlienger K., Chu C.S., Woo E.Y., Rivers P.M., Toll A.J., Hudson B., Maus M.V., Riley J.L., Choi Y., Coukos G., et al. TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted Tcells specific for autologous tumor in late-stage ovarian cancer patients. Clin. Cancer Res. 2003, 9:1517-1527.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1517-1527
    • Schlienger, K.1    Chu, C.S.2    Woo, E.Y.3    Rivers, P.M.4    Toll, A.J.5    Hudson, B.6    Maus, M.V.7    Riley, J.L.8    Choi, Y.9    Coukos, G.10
  • 152
    • 38549177639 scopus 로고    scopus 로고
    • The puzzling role of TRAIL in endothelial cell biology
    • author reply e5-e6
    • Secchiero P., Zauli G. The puzzling role of TRAIL in endothelial cell biology. Arterioscler. Thromb. Vasc. Biol. 2008, 28:e4. author reply e5-e6.
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28
    • Secchiero, P.1    Zauli, G.2
  • 154
    • 84878936788 scopus 로고    scopus 로고
    • Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T Cells
    • Published online April 7, 2013. DOI: 1158/2326-6066
    • Selby M.J., Engelhardt J.J., Quigley M., Henning K.A., Chen T., Srinivasan M., Korman A.J. Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T Cells. Cancer Immunology Research 2013, Published online April 7, 2013. DOI: 1158/2326-6066.
    • (2013) Cancer Immunology Research
    • Selby, M.J.1    Engelhardt, J.J.2    Quigley, M.3    Henning, K.A.4    Chen, T.5    Srinivasan, M.6    Korman, A.J.7
  • 155
    • 0034880059 scopus 로고    scopus 로고
    • Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity
    • Seo N., Hayakawa S., Takigawa M., Tokura Y. Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity. Immunology 2001, 103:449-457.
    • (2001) Immunology , vol.103 , pp. 449-457
    • Seo, N.1    Hayakawa, S.2    Takigawa, M.3    Tokura, Y.4
  • 157
    • 0037008695 scopus 로고    scopus 로고
    • Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells
    • Spinella F., Rosanò L., Di Castro V., Natali P.G., Bagnato A. Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells. J.Biol. Chem. 2002, 277:27850-27855.
    • (2002) J.Biol. Chem. , vol.277 , pp. 27850-27855
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Natali, P.G.4    Bagnato, A.5
  • 158
    • 33847737677 scopus 로고    scopus 로고
    • Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells
    • Spinella F., Rosanò L., Di Castro V., Decandia S., Nicotra M.R., Natali P.G., Bagnato A. Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells. Cancer Res. 2007, 67:1725-1734.
    • (2007) Cancer Res. , vol.67 , pp. 1725-1734
    • Spinella, F.1    Rosanò, L.2    Di Castro, V.3    Decandia, S.4    Nicotra, M.R.5    Natali, P.G.6    Bagnato, A.7
  • 159
    • 0033105695 scopus 로고    scopus 로고
    • Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) Tcells resulting in a failure to lyse tumor cells
    • Steinbrink K., Jonuleit H., Müller G., Schuler G., Knop J., Enk A.H. Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) Tcells resulting in a failure to lyse tumor cells. Blood 1999, 93:1634-1642.
    • (1999) Blood , vol.93 , pp. 1634-1642
    • Steinbrink, K.1    Jonuleit, H.2    Müller, G.3    Schuler, G.4    Knop, J.5    Enk, A.H.6
  • 160
    • 0034614886 scopus 로고    scopus 로고
    • The induction of tolerance by dendritic cells that have captured apoptotic cells
    • Steinman R.M., Turley S., Mellman I., Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J.Exp. Med. 2000, 191:411-416.
    • (2000) J.Exp. Med. , vol.191 , pp. 411-416
    • Steinman, R.M.1    Turley, S.2    Mellman, I.3    Inaba, K.4
  • 161
    • 34547655923 scopus 로고    scopus 로고
    • A unique subset of CD4+CD25highFoxp3+ Tcells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment
    • Strauss L., Bergmann C., Szczepanski M., Gooding W., Johnson J.T., Whiteside T.L. A unique subset of CD4+CD25highFoxp3+ Tcells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment. Clin. Cancer Res. 2007, 13:4345-4354.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4345-4354
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 162
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory Tcells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller R.P., van Duivenvoorde L.M., van Elsas A., Schumacher T.N., Wildenberg M.E., Allison J.P., Toes R.E., Offringa R., Melief C.J. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory Tcells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J.Exp. Med. 2001, 194:823-832.
    • (2001) J.Exp. Med. , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6    Toes, R.E.7    Offringa, R.8    Melief, C.J.9
  • 163
    • 2542470851 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines
    • Takahashi A., Kono K., Ichihara F., Sugai H., Fujii H., Matsumoto Y. Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines. Cancer Immunol. Immunother. 2004, 53:543-550.
    • (2004) Cancer Immunol. Immunother. , vol.53 , pp. 543-550
    • Takahashi, A.1    Kono, K.2    Ichihara, F.3    Sugai, H.4    Fujii, H.5    Matsumoto, Y.6
  • 165
    • 79959312575 scopus 로고    scopus 로고
    • Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
    • Topp M.S., Kufer P., Gökbuget N., Goebeler M., Klinger M., Neumann S., Horst H.A., Raff T., Viardot A., Schmid M., et al. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J.Clin. Oncol. 2011, 29:2493-2498.
    • (2011) J.Clin. Oncol. , vol.29 , pp. 2493-2498
    • Topp, M.S.1    Kufer, P.2    Gökbuget, N.3    Goebeler, M.4    Klinger, M.5    Neumann, S.6    Horst, H.A.7    Raff, T.8    Viardot, A.9    Schmid, M.10
  • 166
    • 33646239606 scopus 로고    scopus 로고
    • Tumor-induced expansion of regulatory Tcells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent
    • Valzasina B., Piconese S., Guiducci C., Colombo M.P. Tumor-induced expansion of regulatory Tcells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent. Cancer Res. 2006, 66:4488-4495.
    • (2006) Cancer Res. , vol.66 , pp. 4488-4495
    • Valzasina, B.1    Piconese, S.2    Guiducci, C.3    Colombo, M.P.4
  • 167
    • 17944364189 scopus 로고    scopus 로고
    • Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy
    • van Elsas A., Sutmuller R.P., Hurwitz A.A., Ziskin J., Villasenor J., Medema J.P., Overwijk W.W., Restifo N.P., Melief C.J., Offringa R., Allison J.P. Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J.Exp. Med. 2001, 194:481-489.
    • (2001) J.Exp. Med. , vol.194 , pp. 481-489
    • van Elsas, A.1    Sutmuller, R.P.2    Hurwitz, A.A.3    Ziskin, J.4    Villasenor, J.5    Medema, J.P.6    Overwijk, W.W.7    Restifo, N.P.8    Melief, C.J.9    Offringa, R.10    Allison, J.P.11
  • 170
    • 76249100089 scopus 로고    scopus 로고
    • Independent regulation of chemokine responsiveness and cytolytic function versus CD8+ Tcell expansion by dendritic cells
    • Watchmaker P.B., Berk E., Muthuswamy R., Mailliard R.B., Urban J.A., Kirkwood J.M., Kalinski P. Independent regulation of chemokine responsiveness and cytolytic function versus CD8+ Tcell expansion by dendritic cells. J.Immunol. 2010, 184:591-597.
    • (2010) J.Immunol. , vol.184 , pp. 591-597
    • Watchmaker, P.B.1    Berk, E.2    Muthuswamy, R.3    Mailliard, R.B.4    Urban, J.A.5    Kirkwood, J.M.6    Kalinski, P.7
  • 172
    • 0036155925 scopus 로고    scopus 로고
    • Tumor-induced death of immune cells: its mechanisms and consequences
    • Whiteside T.L. Tumor-induced death of immune cells: its mechanisms and consequences. Semin. Cancer Biol. 2002, 12:43-50.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 43-50
    • Whiteside, T.L.1
  • 173
    • 31344453943 scopus 로고    scopus 로고
    • Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention
    • Whiteside T.L. Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention. Semin. Cancer Biol. 2006, 16:3-15.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 3-15
    • Whiteside, T.L.1
  • 174
    • 0024465081 scopus 로고
    • Molecular biology and biochemistry of the endothelins
    • Yanagisawa M., Masaki T. Molecular biology and biochemistry of the endothelins. Trends Pharmacol. Sci. 1989, 10:374-378.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 374-378
    • Yanagisawa, M.1    Masaki, T.2
  • 177
    • 38049141544 scopus 로고    scopus 로고
    • A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory Tcells
    • Zarek P.E., Huang C.T., Lutz E.R., Kowalski J., Horton M.R., Linden J., Drake C.G., Powell J.D. A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory Tcells. Blood 2008, 111:251-259.
    • (2008) Blood , vol.111 , pp. 251-259
    • Zarek, P.E.1    Huang, C.T.2    Lutz, E.R.3    Kowalski, J.4    Horton, M.R.5    Linden, J.6    Drake, C.G.7    Powell, J.D.8
  • 179
    • 68849086119 scopus 로고    scopus 로고
    • Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects
    • Zitvogel L., Kroemer G. Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects. J.Clin. Invest. 2009, 119:2127-2130.
    • (2009) J.Clin. Invest. , vol.119 , pp. 2127-2130
    • Zitvogel, L.1    Kroemer, G.2
  • 180
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • Zitvogel L., Tesniere A., Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. Immunol. 2006, 6:715-727.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 181
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 2005, 5:263-274.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.