메뉴 건너뛰기




Volumn 74, Issue 1, 2014, Pages 24-30

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

EID: 84892747845     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1196     Document Type: Article
Times cited : (337)

References (20)
  • 1
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell 2010;141:39-51.
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 2
    • 80053224897 scopus 로고    scopus 로고
    • Mononuclear phagocyte heterogeneity in cancer: Different subsets and activation states reaching out at the tumor site
    • Laoui D, Van Overmeire E, Movahedi K, Van den Bossche J, Schouppe E, Mommer C, et al. Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site. Immunobiology 2011;216:1192-202.
    • (2011) Immunobiology , vol.216 , pp. 1192-1202
    • Laoui, D.1    Van Overmeire, E.2    Movahedi, K.3    Van Den-Bossche, J.4    Schouppe, E.5    Mommer, C.6
  • 3
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006;66:605-12.
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 4
    • 77955038532 scopus 로고    scopus 로고
    • Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes
    • Movahedi K, Laoui D, Gysemans C, Baeten M, Stange G, Van den Bossche J, et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res 2010;70:572839.
    • (2010) Cancer Res , vol.70 , pp. 572839
    • Movahedi, K.1    Laoui, D.2    Gysemans, C.3    Baeten, M.4    Stange, G.5    Van Den-Bossche, J.6
  • 5
    • 34047246527 scopus 로고    scopus 로고
    • Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
    • Wyckoff JB, Wang Y, Lin EY, Li J, Goswami S, Stanley ER, et al. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res 2007;67:2649-56.
    • (2007) Cancer Res , vol.67 , pp. 2649-2656
    • Wyckoff, J.B.1    Wang, Y.2    Lin, E.Y.3    Li, J.4    Goswami, S.5    Stanley, E.R.6
  • 7
    • 84865147481 scopus 로고    scopus 로고
    • Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages
    • Movahedi K, Schoonooghe S, Laoui D, Houbracken I, Waelput W, Breckpot K, et al. Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages. Cancer Res 2012;72:4165-4177.
    • (2012) Cancer Res , vol.72 , pp. 4165-4177
    • Movahedi, K.1    Schoonooghe, S.2    Laoui, D.3    Houbracken, I.4    Waelput, W.5    Breckpot, K.6
  • 8
    • 79958010073 scopus 로고    scopus 로고
    • Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: Interaction and impact on survival
    • Osinsky S, Bubnovskaya L, Ganusevich I, Kovelskaya A, Gumenyuk L, Olijnichenko G, et al. Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: interaction and impact on survival. Clin Transl Oncol 2011;13:133-38.
    • (2011) Clin Transl Oncol , vol.13 , pp. 133-138
    • Osinsky, S.1    Bubnovskaya, L.2    Ganusevich, I.3    Kovelskaya, A.4    Gumenyuk, L.5    Olijnichenko, G.6
  • 9
    • 0141425768 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression in human macrophages, implications for ischemic tissue and hypoxia-regulated gene therapy
    • Burke B, Giannoudis A, Corke KP, Gill D, Wells M, Ziegler-Heitbrock L, et al. Hypoxia-induced gene expression in human macrophages, implications for ischemic tissue and hypoxia-regulated gene therapy. Am J Pathol. 2003;163:1233-43.
    • (2003) Am J Pathol. , vol.163 , pp. 1233-1243
    • Burke, B.1    Giannoudis, A.2    Corke, K.P.3    Gill, D.4    Wells, M.5    Ziegler-Heitbrock, L.6
  • 11
    • 68249140395 scopus 로고    scopus 로고
    • Hypoxia inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
    • Fang H, Hughes R, Murdoch C, Coffelt C, Biswas SK, Harris AL, et al. Hypoxia inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood 2009;144: 844-59.
    • (2009) Blood , vol.144 , pp. 844-859
    • Fang, H.1    Hughes, R.2    Murdoch, C.3    Coffelt, C.4    Biswas, S.K.5    Harris, A.L.6
  • 12
    • 84866542725 scopus 로고    scopus 로고
    • Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF
    • Hamilton JA, Lacey DC, Turner A, de Kok B, Huynh J, Scholz GM. Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF. PLoS One 2012;7:e45853.
    • (2012) PLoS One , vol.7
    • Hamilton, J.A.1    Lacey, D.C.2    Turner, A.3    De Kok, B.4    Huynh, J.5    Scholz, G.M.6
  • 13
    • 59649117924 scopus 로고    scopus 로고
    • Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
    • Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, et al. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell 2009;136: 839-51
    • (2009) Cell , vol.136 , pp. 839-851
    • Mazzone, M.1    Dettori, D.2    Leite De-Oliveira, R.3    Loges, S.4    Schmidt, T.5    Jonckx, B.6
  • 14
  • 15
    • 84857692141 scopus 로고    scopus 로고
    • Differential macrophage programming in the tumor microenvironment
    • Ruffell B, Affara NI, Coussens LM. Differential macrophage programming in the tumor microenvironment. Trends Immunol 2012;33: 119-26.
    • (2012) Trends Immunol , vol.33 , pp. 119-126
    • Ruffell, B.1    Affara, N.I.2    Coussens, L.M.3
  • 16
    • 84876186488 scopus 로고    scopus 로고
    • Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations
    • Schouppe E, De Baetselier P, Van Ginderachter JA, Sarukhan A. Instruction of myeloid cells by the tumor microenvironment: open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations. OncoImmunol 2012;1:1135-45
    • (2012) OncoImmunol , vol.1 , pp. 1135-1145
    • Schouppe, E.1    De Baetselier, P.2    Van Ginderachter, J.A.3    Sarukhan, A.4
  • 17
    • 79953750307 scopus 로고    scopus 로고
    • Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
    • Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, et al. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 2011;19:512-26.
    • (2011) Cancer Cell , vol.19 , pp. 512-526
    • Mazzieri, R.1    Pucci, F.2    Moi, D.3    Zonari, E.4    Ranghetti, A.5
  • 18
    • 77957350018 scopus 로고    scopus 로고
    • Macrophage expression of hypoxia-inducible factor-1α suppresses T-cell function and promotes tumor progression
    • Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, et al. Macrophage expression of hypoxia-inducible factor-1α suppresses T-cell function and promotes tumor progression. Cancer Res 2010;70:7465-75.
    • (2010) Cancer Res , vol.70 , pp. 7465-7475
    • Doedens, A.L.1    Stockmann, C.2    Rubinstein, M.P.3    Liao, D.4    Zhang, N.5    Denardo, D.G.6
  • 19
    • 77955295091 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
    • Imtiyaz HZ, Williams EP, Hickey MM, Patel SA, Durham AC, Yuan LJ, et al. Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation. J Clin Invest 2010;120:2699-14.
    • (2010) J Clin Invest , vol.120 , pp. 2699-2714
    • Imtiyaz, H.Z.1    Williams, E.P.2    Hickey, M.M.3    Patel, S.A.4    Durham, A.C.5    Yuan, L.J.6
  • 20
    • 77649177217 scopus 로고    scopus 로고
    • Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
    • Takeda N, O'Dea EL, Doedens A, Kim JW, Weidemann A, Stockmann C, et al. Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis. Genes Dev 2011;24:491-501.
    • (2011) Genes Dev , vol.24 , pp. 491-501
    • Takeda, N.1    O'Dea, E.L.2    Doedens, A.3    Kim, J.W.4    Weidemann, A.5    Stockmann, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.