New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation

Oncogene

Volumn 29, Issue 50, 2010, Pages 6509-6521

  Swietach, P ^a   Hulikova, A ^a   Vaughan Jones, R D ^a   Harris, A L ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

acid base transport; buffers; cancer; carbonic anhydrase IX; pH

Indexed keywords

ACETAZOLAMIDE; ACID; BICARBONATE; BUFFER; CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE IX INHIBITOR; CARBONATE DEHYDRATASE XII INHIBITOR; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; HYDROGEN; MYXOTHIAZOL; OXYGEN; PIMONIDAZOLE; ROTENONE; UNCLASSIFIED DRUG;

ACID BASE BALANCE; ANTINEOPLASTIC ACTIVITY; CAPILLARY; CELL GROWTH; CELL HYPOXIA; CELL METABOLISM; CELL PH; CELL SURFACE; CLINICAL TRIAL; DIFFUSION; DRUG INHIBITION; EQUILIBRIUM CONSTANT; EXTRACELLULAR MATRIX; GENE CONTROL; GENE EXPRESSION; HUMAN; MEMBRANE TRANSPORT; METABOLIC PARAMETERS; METABOLIC REGULATION; METABOLITE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXYGENATION; PH MEASUREMENT; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SOLID TUMOR; STEADY STATE; TISSUE GROWTH; TUMOR CELL;

ANIMALS; ANTIGENS, NEOPLASM; BICARBONATES; CARBONIC ANHYDRASES; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; FACILITATED DIFFUSION; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; MICE; NEOPLASMS;

EID: 78650308850     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.455     Document Type: Review

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