Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology

PLoS ONE

Volumn 5, Issue 3, 2010, Pages

  Xu, Chen ^a,c   Lo, Agnes ^a   Yammanuru, Anuradha ^a   Tallarico, Aimee St Clair ^a   Brady, Kristen ^a   Murakami, Akikazu ^a   Barteneva, Natasha ^a,b   Zhu, Quan ^a   Marasco, Wayne A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Beijing Tri prime Genetic Engineering Corporation Limited   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE IX; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CARBONATE DEHYDRATASE IX; UNCLASSIFIED DRUG; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; PEPTIDE LIBRARY; TUMOR ANTIGEN; TUMOR MARKER;

ARTICLE; BINDING AFFINITY; CANCER DIAGNOSIS; CANCER IMMUNOTHERAPY; CELL SURFACE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; EMBRYO; ENDOSOME; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EPITOPE MAPPING; HUMAN; HUMAN CELL; INTERNALIZATION; KIDNEY CARCINOMA; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PROTEOLIPOSOME; STRUCTURE ACTIVITY RELATION; BIOTINYLATION; CHEMISTRY; IMMUNOLOGY; IMMUNOTHERAPY; KIDNEY TUMOR; KINETICS; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

MURINAE;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BIOTINYLATION; CARBONIC ANHYDRASES; CARCINOMA, RENAL CELL; CATALYTIC DOMAIN; ENDOSOMES; EPITOPE MAPPING; HUMANS; IMMUNOTHERAPY; KIDNEY NEOPLASMS; KINETICS; PEPTIDE LIBRARY; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; TUMOR MARKERS, BIOLOGICAL;

EID: 77949716901     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009625     Document Type: Article

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