Acidity generated by the tumor microenvironment drives local invasion

Cancer Research

Volumn 73, Issue 5, 2013, Pages 1524-1535

  Estrella, Veronica ^a   Chen, Tingan ^c   Lloyd, Mark ^c   Wojtkowiak, Jonathan ^a   Cornnell, Heather H ^a   Ibrahim Hashim, Arig ^a   Bailey, Kate ^a   Balagurunathan, Yoganand ^a   Rothberg, Jennifer M ^d   Sloane, Bonnie F ^e   Johnson, Joseph ^d   Gatenby, Robert A ^a,b   Gillies, Robert J ^a,b,c  

^a Departments of Cancer Imaging and Metabolism   (United States)

^b Department of Radiology ^*  (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d Cancer Biology Program   (United States)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; GLUCOSE TRANSPORTER 1; SODIUM PROTON EXCHANGE PROTEIN 1;

ACIDITY; ACIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MICROSCOPY; MOUSE; NONHUMAN; PERITUMORAL ACIDOSIS; PERITUMORAL PH; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID TUMOR; TUMOR MICROENVIRONMENT;

ANIMALS; DRUGS, CHINESE HERBAL; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, SCID; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASMS; SODIUM BICARBONATE; TUMOR MICROENVIRONMENT;

EID: 84874886049     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2796     Document Type: Article

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