메뉴 건너뛰기




Volumn 108, Issue 40, 2011, Pages 16663-16668

Erratum: CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 40 (16663-16668) DOI: 10.1073/pnas.1106123108);CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

Author keywords

Cancer metabolism; Embigin; EMMPRIN; Lactate transport; Warburg effect

Indexed keywords

CD147 ANTIGEN; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 2; MONOCARBOXYLATE TRANSPORTER 4; SHORT HAIRPIN RNA;

EID: 80053640489     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1219161109     Document Type: Erratum
Times cited : (367)

References (45)
  • 1
    • 37549013776 scopus 로고    scopus 로고
    • A microenvironmental model of carcinogenesis
    • Gatenby RA, Gillies RJ (2008) A microenvironmental model of carcinogenesis. Nat Rev Cancer 8:56-61.
    • (2008) Nat Rev Cancer , vol.8 , pp. 56-61
    • Gatenby, R.A.1    Gillies, R.J.2
  • 2
    • 44449147036 scopus 로고    scopus 로고
    • Tumor Cell Metabolism: Cancer's Achilles' Heel
    • DOI 10.1016/j.ccr.2008.05.005, PII S1535610808001608
    • Kroemer G, Pouyssegur J (2008) Tumor cell metabolism: Cancer's Achilles' heel. Cancer Cell 13:472-482. (Pubitemid 351766797)
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 3
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB (2009) Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 4
    • 77953209898 scopus 로고    scopus 로고
    • Q&A: Cancer: Clues from cell metabolism
    • Kaelin WG, Jr., Thompson CB (2010) Q&A: Cancer: Clues from cell metabolism. Nature 465:562-564.
    • (2010) Nature , vol.465 , pp. 562-564
    • Kaelin Jr., W.G.1    Thompson, C.B.2
  • 5
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: Upstream and downstream of cancer metabolism
    • Semenza GL (2010) HIF-1: Upstream and downstream of cancer metabolism. Curr Opin Genet Dev 20:51-56.
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 51-56
    • Semenza, G.L.1
  • 6
    • 77949967131 scopus 로고    scopus 로고
    • Targeting metabolic transformation for cancer therapy
    • Tennant DA, Durán RV, Gottlieb E (2010) Targeting metabolic transformation for cancer therapy. Nat Rev Cancer 10:267-277.
    • (2010) Nat Rev Cancer , vol.10 , pp. 267-277
    • Tennant, D.A.1    Durán, R.V.2    Gottlieb, E.3
  • 7
    • 79955076736 scopus 로고    scopus 로고
    • Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle
    • Tudzarova S, et al. (2011) Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci USA 108:5278-5283.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 5278-5283
    • Tudzarova, S.1
  • 8
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • DOI 10.1038/nature04871, PII NATURE04871
    • Pouysségur J, Dayan F, Mazure NM (2006) Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441:437-443. (Pubitemid 44050138)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 10
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 11
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • DOI 10.1016/j.ccr.2006.04.023, PII S1535610806001450
    • Fantin VR, St-Pierre J, Leder P (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9: 425-434. (Pubitemid 43832190)
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 14
    • 57449097020 scopus 로고    scopus 로고
    • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    • Sonveaux P, et al. (2008) Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest 118:3930-3942.
    • (2008) J Clin Invest , vol.118 , pp. 3930-3942
    • Sonveaux, P.1
  • 15
    • 76649126249 scopus 로고    scopus 로고
    • Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
    • Le A, et al. (2010) Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci USA 107:2037-2042.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2037-2042
    • Le, A.1
  • 16
    • 0035237389 scopus 로고    scopus 로고
    • pHi, aerobic glycolysis and vascular endothelial growth factor in tumour growth
    • and discussion 196-198
    • Pouyssegur J, Franchi A, Pages G (2001) pHi, aerobic glycolysis and vascular endothelial growth factor in tumour growth. Novartis Found Symp 240:186-196, and discussion 196-198.
    • (2001) Novartis Found Symp , vol.240 , pp. 186-196
    • Pouyssegur, J.1    Franchi, A.2    Pages, G.3
  • 17
    • 0021352692 scopus 로고
    • + antiport
    • L'Allemain G, Paris S, Pouysségur J (1984) Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport. J Biol Chem 259:5809-5815. (Pubitemid 14145050)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.9 , pp. 5809-5815
    • L'Allemain, G.1    Paris, S.2    Pouyssegur, J.3
  • 19
    • 58249094845 scopus 로고    scopus 로고
    • Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
    • Chiche J, et al. (2009) Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69:358-368.
    • (2009) Cancer Res , vol.69 , pp. 358-368
    • Chiche, J.1
  • 20
    • 33646917296 scopus 로고    scopus 로고
    • The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism
    • DOI 10.1074/jbc.M511397200
    • Ullah MS, Davies AJ, Halestrap AP (2006) The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. J Biol Chem 281:9030-9037. (Pubitemid 43864615)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.14 , pp. 9030-9037
    • Ullah, M.S.1    Davies, A.J.2    Halestrap, A.P.3
  • 21
    • 84857105546 scopus 로고    scopus 로고
    • The monocarboxylate transporter 1 (MCT1) and Hypoxia-induced MCT4 are key targets promoting tumor cell surviva
    • Chiche J, Le Floch R, Roux D, Pouysségur J (2008) The monocarboxylate transporter 1 (MCT1) and Hypoxia-induced MCT4 are key targets promoting tumor cell surviva. Eur J Cancer, Suppl 6:24.
    • (2008) Eur J Cancer, Suppl , vol.6 , pp. 24
    • Chiche, J.1    Le Floch, R.2    Roux, D.3    Pouysségur, J.4
  • 22
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family - From monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
    • DOI 10.1007/s00424-003-1067-2, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Halestrap AP, Meredith D (2004) The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch 447:619-628. (Pubitemid 38241446)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 23
    • 0034254638 scopus 로고    scopus 로고
    • CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
    • Kirk P, et al. (2000) CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J 19:3896-3904. (Pubitemid 30608530)
    • (2000) EMBO Journal , vol.19 , Issue.15 , pp. 3896-3904
    • Kirk, P.1    Wilson, M.C.2    Heddle, C.3    Brown, M.H.4    Barclay, A.N.5    Halestrap, A.P.6
  • 25
    • 75149178349 scopus 로고    scopus 로고
    • Tumor metabolism of lactate: The influence and therapeutic potential for MCT and CD147 regulation
    • Kennedy KM, Dewhirst MW (2010) Tumor metabolism of lactate: The influence and therapeutic potential for MCT and CD147 regulation. Future Oncol 6:127-148.
    • (2010) Future Oncol , vol.6 , pp. 127-148
    • Kennedy, K.M.1    Dewhirst, M.W.2
  • 26
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, et al. (1995) The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 55: 434-439.
    • (1995) Cancer Res , vol.55 , pp. 434-439
    • Biswas, C.1
  • 28
    • 33644790739 scopus 로고    scopus 로고
    • Monocarboxylate transporter MCT1 is a target for immunosuppression
    • Murray CM, et al. (2005) Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol 1:371-376.
    • (2005) Nat Chem Biol , vol.1 , pp. 371-376
    • Murray, C.M.1
  • 30
    • 0019471829 scopus 로고
    • A genetic approach to the role of energy metabolism in the growth of tumor cells: Tumorigenicity of fibroblast mutants deficient either in glycolysis or in respiration
    • DOI 10.1002/ijc.2910270614
    • Franchi A, Silvestre P, Pouysségur J (1981) A genetic approach to the role of energy metabolism in the growth of tumor cells: Tumorigenicity of fibroblast mutants deficient either in glycolysis or in respiration. Int J Cancer 27:819-827. (Pubitemid 11125620)
    • (1981) International Journal of Cancer , vol.27 , Issue.6 , pp. 819-827
    • Franchi, A.1    Silvestre, P.2    Pouyssegur, J.3
  • 31
    • 74349094033 scopus 로고    scopus 로고
    • AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10
    • Ovens MJ, Davies AJ, Wilson MC, Murray CM, Halestrap AP (2010) AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Biochem J 425:523-530.
    • (2010) Biochem J , vol.425 , pp. 523-530
    • Ovens, M.J.1    Davies, A.J.2    Wilson, M.C.3    Murray, C.M.4    Halestrap, A.P.5
  • 32
    • 70349307027 scopus 로고    scopus 로고
    • CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
    • Schneiderhan W, et al. (2009) CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut 58: 1391-1398.
    • (2009) Gut , vol.58 , pp. 1391-1398
    • Schneiderhan, W.1
  • 34
    • 67749133881 scopus 로고    scopus 로고
    • Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle
    • Wilson MC, Meredith D, Bunnun C, Sessions RB, Halestrap AP (2009) Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle. J Biol Chem 284: 20011-20021.
    • (2009) J Biol Chem , vol.284 , pp. 20011-20021
    • Wilson, M.C.1    Meredith, D.2    Bunnun, C.3    Sessions, R.B.4    Halestrap, A.P.5
  • 35
    • 67649829693 scopus 로고    scopus 로고
    • A novel role for embigin to promote sprouting of motor nerve terminals at the neuromuscular junction
    • Lain E, et al. (2009) A novel role for embigin to promote sprouting of motor nerve terminals at the neuromuscular junction. J Biol Chem 284:8930-8939.
    • (2009) J Biol Chem , vol.284 , pp. 8930-8939
    • Lain, E.1
  • 38
    • 50649105780 scopus 로고    scopus 로고
    • Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths
    • Swietach P, et al. (2008) Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. J Biol Chem 283: 20473-20483.
    • (2008) J Biol Chem , vol.283 , pp. 20473-20483
    • Swietach, P.1
  • 39
    • 79955490807 scopus 로고    scopus 로고
    • Targeting tumor hypoxia: Suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
    • correction (2011) 71:4733
    • Lou Y, et al. (2011) Targeting tumor hypoxia: Suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res 71:3364-3376, correction (2011) 71:4733.
    • (2011) Cancer Res , vol.71 , pp. 3364-3376
    • Lou, Y.1
  • 40
    • 84856327997 scopus 로고    scopus 로고
    • In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH
    • in press 10.1002/ijc.26125
    • Chiche J, et al. (2011) In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH. Int J Cancer, in press 10.1002/ijc.26125.
    • (2011) Int J Cancer
    • Chiche, J.1
  • 41
    • 0034525940 scopus 로고    scopus 로고
    • Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle
    • DOI 10.1111/j.1469-7793.2000.00285.x
    • Manning Fox JE, Meredith D, Halestrap AP (2000) Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol 529:285-293. (Pubitemid 32040847)
    • (2000) Journal of Physiology , vol.529 , Issue.2 , pp. 285-293
    • Manning, F.J.E.1    Meredith, D.2    Halestrap, A.P.3
  • 42
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Bröer S (2000) The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 350:219-227.
    • (2000) Biochem J , vol.350 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Bröer, S.5
  • 43
    • 34249293335 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
    • DOI 10.1158/0008-5472.CAN-06-3184
    • Gallagher SM, Castorino JJ, Wang D, Philp NJ (2007) Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. Cancer Res 67:4182-4189. (Pubitemid 46815064)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4182-4189
    • Gallagher, S.M.1    Castorino, J.J.2    Wang, D.3    Philp, N.J.4
  • 44
    • 65249168811 scopus 로고    scopus 로고
    • Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration
    • Gallagher SM, Castorino JJ, Philp NJ (2009) Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration. Am J Physiol Cell Physiol 296:C414-C421.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Gallagher, S.M.1    Castorino, J.J.2    Philp, N.J.3
  • 45
    • 33744832157 scopus 로고    scopus 로고
    • + exchanger NHE1 in cell migration
    • DOI 10.1111/j.1748-1716.2006.01543.x
    • Stock C, Schwab A (2006) Role of the Na/H exchanger NHE1 in cell migration. Acta Physiol (Oxf) 187:149-157. (Pubitemid 43828772)
    • (2006) Acta Physiologica , vol.187 , Issue.1-2 , pp. 149-157
    • Stock, C.1    Schwab, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.