메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

Peroxisome Proliferator Activated Receptor-α/Hypoxia Inducible Factor-1α Interplay Sustains Carbonic Anhydrase IX and Apoliprotein E Expression in Breast Cancer Stem Cells

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CARBONATE DEHYDRATASE IX; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; MICRORNA; MICRORNA 130B; MICRORNA 17 5P; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARBONATE DEHYDRATASE; MIRN130 MICRORNA, HUMAN; MIRN17 MICRORNA, HUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84872861339     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054968     Document Type: Article
Times cited : (37)

References (62)
  • 1
    • 80053406107 scopus 로고    scopus 로고
    • Breast cancer-one term, many entities
    • Bertos NR, Park M, (2011) Breast cancer-one term, many entities?. J Clin Invest 121: 3789-3796.
    • (2011) J Clin Invest , vol.121 , pp. 3789-3796
    • Bertos, N.R.1    Park, M.2
  • 2
    • 80053393750 scopus 로고    scopus 로고
    • Insight into the heterogeneity of breast cancer through next-generation sequencing
    • Russnes HG, Navin N, Hicks J, Borresen-Dale A, (2011) Insight into the heterogeneity of breast cancer through next-generation sequencing. J Clin Invest 121: 3810-3818.
    • (2011) J Clin Invest , vol.121 , pp. 3810-3818
    • Russnes, H.G.1    Navin, N.2    Hicks, J.3    Borresen-Dale, A.4
  • 4
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S, Wicha MS, (2011) Targeting breast cancer stem cells. J Clin Oncol 28: 4006-4012.
    • (2011) J Clin Oncol , vol.28 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 5
    • 84857817163 scopus 로고    scopus 로고
    • Slug and Sox9 cooperatively determine the mammary stem cell state
    • Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, et al. (2012) Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 148: 1015-1028.
    • (2012) Cell , vol.148 , pp. 1015-1028
    • Guo, W.1    Keckesova, Z.2    Donaher, J.L.3    Shibue, T.4    Tischler, V.5
  • 6
    • 84865494894 scopus 로고    scopus 로고
    • Stem cells in breast tumours: Are they ready for the clinic
    • Ablett MP, Singh JK, Clarke RB, (2012) Stem cells in breast tumours: Are they ready for the clinic? Eur J Cancer 48: 2104-2116.
    • (2012) Eur J Cancer , vol.48 , pp. 2104-2116
    • Ablett, M.P.1    Singh, J.K.2    Clarke, R.B.3
  • 7
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, et al. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17: 1253-1270.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5
  • 8
    • 33847637262 scopus 로고    scopus 로고
    • p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in humanstem/progenitor cells of the mammary gland expanded in vitro as mammospheres
    • Sansone P, Storci G, Giovannini C, Pandolfi S, Pianetti S, et al. (2007) p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in humanstem/progenitor cells of the mammary gland expanded in vitro as mammospheres. Stem Cells 25: 807-815.
    • (2007) Stem Cells , vol.25 , pp. 807-815
    • Sansone, P.1    Storci, G.2    Giovannini, C.3    Pandolfi, S.4    Pianetti, S.5
  • 9
    • 36849039660 scopus 로고    scopus 로고
    • IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
    • Sansone P, Storci G, Tavolari S, Guarnieri T, Giovannini C, et al. (2007) IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J Clin Invest 117: 3988-4002.
    • (2007) J Clin Invest , vol.117 , pp. 3988-4002
    • Sansone, P.1    Storci, G.2    Tavolari, S.3    Guarnieri, T.4    Giovannini, C.5
  • 10
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells, cytokine networks, and the tumor microenvironment
    • Korkaya H, Liu S, Wicha MS, (2011) Breast cancer stem cells, cytokine networks, and the tumor microenvironment. J Clin Invest 3: 3804-3809.
    • (2011) J Clin Invest , vol.3 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 11
    • 51649112926 scopus 로고    scopus 로고
    • NF-κB pathway inhibitors preferentially inhibit breast cancer stem-like cells
    • Zhou J, Zhang H, Gu P, Bai J, Margolick JB, et al. (2008) NF-κB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res Tr 111: 419-427.
    • (2008) Breast Cancer Res Tr , vol.111 , pp. 419-427
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Bai, J.4    Margolick, J.B.5
  • 12
    • 77957735709 scopus 로고    scopus 로고
    • TNFα up-regulates SLUG via the NF-κB/HIF1α axis, which imparts breast cancer cells with a stem cell-like phenotype
    • Storci G, Sansone P, Mari S, D'Uva G, Tavolari S, et al. (2010) TNFα up-regulates SLUG via the NF-κB/HIF1α axis, which imparts breast cancer cells with a stem cell-like phenotype. J Cell Physiol 225: 682-691.
    • (2010) J Cell Physiol , vol.225 , pp. 682-691
    • Storci, G.1    Sansone, P.2    Mari, S.3    D'Uva, G.4    Tavolari, S.5
  • 13
    • 77955187052 scopus 로고    scopus 로고
    • SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24-phenotype
    • Bhat-Nakshatri P, Appaiah H, Ballas C, Pick-Franke P, Goulet Jr R, et al. (2010) SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24-phenotype. BMC Cancer 10: 411-420.
    • (2010) BMC Cancer , vol.10 , pp. 411-420
    • Bhat-Nakshatri, P.1    Appaiah, H.2    Ballas, C.3    Pick-Franke, P.4    Goulet Jr, R.5
  • 14
    • 78751623400 scopus 로고    scopus 로고
    • Tumor-initiating stem-likem cells in human prostate cancer exhibit increased NF-κB signaling
    • Rajasekhar V, Studer L, Gerald W, Socci ND, Scher HI, (2011) Tumor-initiating stem-likem cells in human prostate cancer exhibit increased NF-κB signaling. Nat Commun 12: 162.
    • (2011) Nat Commun , vol.12 , pp. 162
    • Rajasekhar, V.1    Studer, L.2    Gerald, W.3    Socci, N.D.4    Scher, H.I.5
  • 16
    • 79952092993 scopus 로고    scopus 로고
    • Leukemia stem cells and microenvironment: biology and therapeutic targeting
    • Konopleva MY, Jordan CT, (2011) Leukemia stem cells and microenvironment: biology and therapeutic targeting. J Clin Oncol 29: 591-599.
    • (2011) J Clin Oncol , vol.29 , pp. 591-599
    • Konopleva, M.Y.1    Jordan, C.T.2
  • 17
    • 80053030114 scopus 로고    scopus 로고
    • The cancer stem cell niche-there goes the neighborhood
    • Cabarcas SM, Mathews LA, Farrar WL, (2011) The cancer stem cell niche-there goes the neighborhood?. Int J Cancer 129: 2315-2327.
    • (2011) Int J Cancer , vol.129 , pp. 2315-2327
    • Cabarcas, S.M.1    Mathews, L.A.2    Farrar, W.L.3
  • 18
    • 83555177230 scopus 로고    scopus 로고
    • Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example
    • Bonafè M, Storci G, Franceschi C, (2011) Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example. Bioessays 34: 40-49.
    • (2011) Bioessays , vol.34 , pp. 40-49
    • Bonafè, M.1    Storci, G.2    Franceschi, C.3
  • 19
    • 80053012538 scopus 로고    scopus 로고
    • Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells
    • Rudnick JA, Arendt LM, Klebba I, Hinds JW, Vandana I, et al. (2011) Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS One 6: e24605.
    • (2011) PLoS One , vol.6
    • Rudnick, J.A.1    Arendt, L.M.2    Klebba, I.3    Hinds, J.W.4    Vandana, I.5
  • 20
    • 84862894073 scopus 로고    scopus 로고
    • Roles of the hypoxia response system in hematopoietic and leukemic stem cells
    • Takubo K, Suda T, (2012) Roles of the hypoxia response system in hematopoietic and leukemic stem cells. Int J Hematol 95: 478-483.
    • (2012) Int J Hematol , vol.95 , pp. 478-483
    • Takubo, K.1    Suda, T.2
  • 21
    • 77950838848 scopus 로고    scopus 로고
    • Hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha
    • Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, et al. (2010) Hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain 133: 983-995.
    • (2010) Brain , vol.133 , pp. 983-995
    • Seidel, S.1    Garvalov, B.K.2    Wirta, V.3    von Stechow, L.4    Schänzer, A.5
  • 22
    • 84856237720 scopus 로고    scopus 로고
    • Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain
    • Svastova E, Witarski W, Csaderova L, Kosik I, Svarkova L, et al. (2012) Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain. J Biol Chem 287: 3392-3402.
    • (2012) J Biol Chem , vol.287 , pp. 3392-3402
    • Svastova, E.1    Witarski, W.2    Csaderova, L.3    Kosik, I.4    Svarkova, L.5
  • 23
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumorigenesis
    • Rankin EB, Giaccia AJ, (2011) The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 15: 678-85.
    • (2011) Cell Death Differ , vol.15 , pp. 678-685
    • Rankin, E.B.1    Giaccia, A.J.2
  • 24
    • 84862118662 scopus 로고    scopus 로고
    • Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells
    • Papi A, Guarnieri T, Storci G, Santini D, Ceccarelli C, et al. (2012) Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells. Cell Death Differ 19: 1208-1219.
    • (2012) Cell Death Differ , vol.19 , pp. 1208-1219
    • Papi, A.1    Guarnieri, T.2    Storci, G.3    Santini, D.4    Ceccarelli, C.5
  • 25
    • 0034965596 scopus 로고    scopus 로고
    • PPAR in inflammation control
    • Delerive P, (2001) PPAR in inflammation control. J Endocrinol 169: 453-459.
    • (2001) J Endocrinol , vol.169 , pp. 453-459
    • Delerive, P.1
  • 26
    • 52749088120 scopus 로고    scopus 로고
    • The many faces of PPARγ: anti-inflammatory by any means
    • Szanto A, Nagy L, (2008) The many faces of PPARγ: anti-inflammatory by any means?. Immunobiology 213: 789-803.
    • (2008) Immunobiology , vol.213 , pp. 789-803
    • Szanto, A.1    Nagy, L.2
  • 27
    • 77956229623 scopus 로고    scopus 로고
    • RXRγ and PPARγ Ligands in Combination to Inhibit Proliferation and Invasiveness in Colon Cancer Cells
    • Papi A, Rocchi P, Ferreri AM, Orlandi M, (2010) RXRγ and PPARγ Ligands in Combination to Inhibit Proliferation and Invasiveness in Colon Cancer Cells. Cancer Lett 297: 65-72.
    • (2010) Cancer Lett , vol.297 , pp. 65-72
    • Papi, A.1    Rocchi, P.2    Ferreri, A.M.3    Orlandi, M.4
  • 28
    • 65949117036 scopus 로고    scopus 로고
    • PPARγ and RXR ligands act sinergistically as potent antineoplastic agents in vitro and in vivo glioma models
    • Papi A, Tatenhorst L, Terwel D, Hermes M, Kummer MP, et al. (2009) PPARγ and RXR ligands act sinergistically as potent antineoplastic agents in vitro and in vivo glioma models. J Neurochem 109: 1779-1790.
    • (2009) J Neurochem , vol.109 , pp. 1779-1790
    • Papi, A.1    Tatenhorst, L.2    Terwel, D.3    Hermes, M.4    Kummer, M.P.5
  • 29
    • 70349257304 scopus 로고    scopus 로고
    • Combined low doses of PPARγ and RXR ligands trigger an intrinsic apoptotic pathway in human breast cancer cells
    • Bonofiglio D, Cione E, Qi H, Pingitore A, Perri M, et al. (2009) Combined low doses of PPARγ and RXR ligands trigger an intrinsic apoptotic pathway in human breast cancer cells. Am J Pathol 175: 1270-1280.
    • (2009) Am J Pathol , vol.175 , pp. 1270-1280
    • Bonofiglio, D.1    Cione, E.2    Qi, H.3    Pingitore, A.4    Perri, M.5
  • 30
    • 0034943192 scopus 로고    scopus 로고
    • PPARγ expression in human malignant and normal brain, breast and prostate-derive cells
    • Nwankwo JO, (2001) PPARγ expression in human malignant and normal brain, breast and prostate-derive cells. Prostag Leukotr Ess 64: 241-245.
    • (2001) Prostag Leukotr Ess , vol.64 , pp. 241-245
    • Nwankwo, J.O.1
  • 31
    • 84055217307 scopus 로고    scopus 로고
    • Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits PPARγ expression and promotes pancreatic cancer progression in mice
    • Maniati E, Bossard M, Cook N, Candido JB, Emami-Shahri N, et al. (2011) Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits PPARγ expression and promotes pancreatic cancer progression in mice. J Clin Invest 12: 4685-4699.
    • (2011) J Clin Invest , vol.12 , pp. 4685-4699
    • Maniati, E.1    Bossard, M.2    Cook, N.3    Candido, J.B.4    Emami-Shahri, N.5
  • 32
    • 78650036829 scopus 로고    scopus 로고
    • WY-14643, a selective PPAR{alpha} agonist, induces proinflammatory and proangiogenic responses in human ocular cells
    • Zhang JZ, Ward KW, (2010) WY-14643, a selective PPAR{alpha} agonist, induces proinflammatory and proangiogenic responses in human ocular cells. Int J Toxicol 29: 496-504.
    • (2010) Int J Toxicol , vol.29 , pp. 496-504
    • Zhang, J.Z.1    Ward, K.W.2
  • 33
    • 84866521955 scopus 로고    scopus 로고
    • Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy
    • Galzio R, Cristiano L, Fidoamore A, Cifone MG, Benedetti E, et al. (2012) Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy. J Cell Biochem 113: 3342-3352.
    • (2012) J Cell Biochem , vol.113 , pp. 3342-3352
    • Galzio, R.1    Cristiano, L.2    Fidoamore, A.3    Cifone, M.G.4    Benedetti, E.5
  • 34
    • 79959863770 scopus 로고    scopus 로고
    • TGFβ/TNFα-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype
    • Asiedu MK, Ingle JN, Behrens MD, Radisky DC, Knutson KL, (2011) TGFβ/TNFα-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype. Cancer Res 71: 4707-4719.
    • (2011) Cancer Res , vol.71 , pp. 4707-4719
    • Asiedu, M.K.1    Ingle, J.N.2    Behrens, M.D.3    Radisky, D.C.4    Knutson, K.L.5
  • 35
    • 79958265710 scopus 로고    scopus 로고
    • Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
    • Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, (2011) al (2011) Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 145: 926-940.
    • (2011) Cell , vol.145 , pp. 926-940
    • Scheel, C.1    Eaton, E.N.2    Li, S.H.3    Chaffer, C.L.4    Reinhardt, F.5
  • 36
    • 80051752025 scopus 로고    scopus 로고
    • MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6
    • Saito K, Kondo E, Matsushita M, (2011) MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6. Nucleic Acids Res 39: 6086-6099.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6086-6099
    • Saito, K.1    Kondo, E.2    Matsushita, M.3
  • 37
    • 79251544878 scopus 로고    scopus 로고
    • miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression
    • Lee EK, Lee MJ, Abdelmohsen K, Kim W, Kim MM, et al. (2011) miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol 31: 626-638.
    • (2011) Mol Cell Biol , vol.31 , pp. 626-638
    • Lee, E.K.1    Lee, M.J.2    Abdelmohsen, K.3    Kim, W.4    Kim, M.M.5
  • 38
    • 62749124795 scopus 로고    scopus 로고
    • Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show
    • Kaluz S, Kaluzová M, Liao SY, Lerman M, Stanbridge EJ, (2009) Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?. Biochim Biophys Acta 1795: 162-72.
    • (2009) Biochim Biophys Acta , vol.1795 , pp. 162-172
    • Kaluz, S.1    Kaluzová, M.2    Liao, S.Y.3    Lerman, M.4    Stanbridge, E.J.5
  • 40
    • 49049106608 scopus 로고    scopus 로고
    • Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity
    • Pincheira R, Castro AF, Ozes ON, Idumalla PS, Donner DB, (2008) Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity. J Immunol 181: 1288-98.
    • (2008) J Immunol , vol.181 , pp. 1288-1298
    • Pincheira, R.1    Castro, A.F.2    Ozes, O.N.3    Idumalla, P.S.4    Donner, D.B.5
  • 41
    • 79955016335 scopus 로고    scopus 로고
    • Progression of chronic myelomonocytic leukaemia to acute myeloid leukaemia with expression of tumour necrosis factor-α and its receptors
    • Nakayama-Ichiyama S, Yokote T, Iwaki K, Takubo T, Tsuji M, et al. (2011) Progression of chronic myelomonocytic leukaemia to acute myeloid leukaemia with expression of tumour necrosis factor-α and its receptors. Br J Haematol. 153: 419.
    • (2011) Br J Haematol , vol.153 , pp. 419
    • Nakayama-Ichiyama, S.1    Yokote, T.2    Iwaki, K.3    Takubo, T.4    Tsuji, M.5
  • 42
    • 78851469895 scopus 로고    scopus 로고
    • TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells
    • Twu YC, Gold MR, Teh HS, (2011) TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells. Eur J Immunol 41: 335-444.
    • (2011) Eur J Immunol , vol.41 , pp. 335-444
    • Twu, Y.C.1    Gold, M.R.2    Teh, H.S.3
  • 43
    • 38349043768 scopus 로고    scopus 로고
    • TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways
    • Rivas MA, Carnevale RP, Proietti CJ, Rosemblit C, Beguelin W, et al. (2008) TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways. Exp Cell Res 314: 509-529.
    • (2008) Exp Cell Res , vol.314 , pp. 509-529
    • Rivas, M.A.1    Carnevale, R.P.2    Proietti, C.J.3    Rosemblit, C.4    Beguelin, W.5
  • 44
    • 79952121979 scopus 로고    scopus 로고
    • Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
    • Iliopoulos D, Hirsch HA, Wang G, Struhl K, (2011) Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. P Natl Acad Sci USA 108: 1397-1402.
    • (2011) P Natl Acad Sci USA , vol.108 , pp. 1397-1402
    • Iliopoulos, D.1    Hirsch, H.A.2    Wang, G.3    Struhl, K.4
  • 45
    • 55349104462 scopus 로고    scopus 로고
    • Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner
    • Studebaker AW, Storci G, Werbeck JL, Sansone P, Sasser AK, et al. (2008) Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner. Cancer Res 68: 9087-9095.
    • (2008) Cancer Res , vol.68 , pp. 9087-9095
    • Studebaker, A.W.1    Storci, G.2    Werbeck, J.L.3    Sansone, P.4    Sasser, A.K.5
  • 46
    • 80255131336 scopus 로고    scopus 로고
    • MiRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2
    • Pfaff N, Fiedler J, Holzmann A, Schambach A, Moritz T, et al. (2011) MiRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2. EMBO J 12: 1153-1159.
    • (2011) EMBO J , vol.12 , pp. 1153-1159
    • Pfaff, N.1    Fiedler, J.2    Holzmann, A.3    Schambach, A.4    Moritz, T.5
  • 47
    • 78649681554 scopus 로고    scopus 로고
    • miR-130b Promotes CD133+ liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
    • Ma S, Tang KH, Chan YP, Lee TK, Kwan PS, et al. (2010) miR-130b Promotes CD133+ liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell 7: 694-707.
    • (2010) Cell Stem Cell , vol.7 , pp. 694-707
    • Ma, S.1    Tang, K.H.2    Chan, Y.P.3    Lee, T.K.4    Kwan, P.S.5
  • 48
    • 48649102010 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
    • Taguchi A, Yanagisawa K, Tanaka M, Cao K, Matsuyama Y, et al. (2008) Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster. Cancer Res 68: 5540-5545.
    • (2008) Cancer Res , vol.68 , pp. 5540-5545
    • Taguchi, A.1    Yanagisawa, K.2    Tanaka, M.3    Cao, K.4    Matsuyama, Y.5
  • 49
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • Yan HL, Xue G, Mei Q, Wang YZ, Ding FX, et al. (2009) Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J 28: 2719-2732.
    • (2009) EMBO J , vol.28 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3    Wang, Y.Z.4    Ding, F.X.5
  • 50
    • 84857355139 scopus 로고    scopus 로고
    • Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer
    • Kim K, Chadalapaka G, Lee SO, Yamada D, Sastre-Garau X, et al. (2012) Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer. Oncogene 31: 1034-1044.
    • (2012) Oncogene , vol.31 , pp. 1034-1044
    • Kim, K.1    Chadalapaka, G.2    Lee, S.O.3    Yamada, D.4    Sastre-Garau, X.5
  • 51
    • 0028111173 scopus 로고
    • Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
    • Pastorek J, Pastoreková S, Callebaut I, Mornon JP, Zelník V, et al. (1994) Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9: 2877-2888.
    • (1994) Oncogene , vol.9 , pp. 2877-2888
    • Pastorek, J.1    Pastoreková, S.2    Callebaut, I.3    Mornon, J.P.4    Zelník, V.5
  • 52
    • 79955490807 scopus 로고    scopus 로고
    • Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
    • Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, et al. (2011) Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res 71: 3364-3376.
    • (2011) Cancer Res , vol.71 , pp. 3364-3376
    • Lou, Y.1    McDonald, P.C.2    Oloumi, A.3    Chia, S.4    Ostlund, C.5
  • 53
    • 58749090733 scopus 로고    scopus 로고
    • The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy
    • Tan EY, Yan M, Campo L, Han C, Takano E, et al. (2009) The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy. Br J Cancer 100: 405-411.
    • (2009) Br J Cancer , vol.100 , pp. 405-411
    • Tan, E.Y.1    Yan, M.2    Campo, L.3    Han, C.4    Takano, E.5
  • 54
    • 80053563164 scopus 로고    scopus 로고
    • Interfering with pH regulation in tumours as a therapeutic strategy
    • Neri D, Supuran CT, (2011) Interfering with pH regulation in tumours as a therapeutic strategy. Nat Rev Drug Discov 10: 767-777.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 767-777
    • Neri, D.1    Supuran, C.T.2
  • 55
    • 80052659139 scopus 로고    scopus 로고
    • Cross-talk between apolipoprotein E and cytokines
    • doi: 10.1155/2011/949072
    • Zhang H, Wu LM, Wu J (2011) Cross-talk between apolipoprotein E and cytokines. Mediators Inflamm doi: 10.1155/2011/949072.
    • (2011) Mediators Inflamm
    • Zhang, H.1    Wu, L.M.2    Wu, J.3
  • 56
    • 0033814562 scopus 로고    scopus 로고
    • Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a "frailty gene," not a "longevity gene"
    • Gerdes LU, Jeune B, Ranberg KA, Nybo H, Vaupel JW, (2000) Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a "frailty gene," not a "longevity gene". Genet Epidemiol 19: 202-210.
    • (2000) Genet Epidemiol , vol.19 , pp. 202-210
    • Gerdes, L.U.1    Jeune, B.2    Ranberg, K.A.3    Nybo, H.4    Vaupel, J.W.5
  • 57
    • 84874780018 scopus 로고    scopus 로고
    • Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model
    • doi: 10.1038
    • Alikhani N, Ferguson RD, Novosyadlyy R, Gallagher EJ, Scheinman EJ,et al. (2012) Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model. Oncogene doi: 10.1038.
    • (2012) Oncogene
    • Alikhani, N.1    Ferguson, R.D.2    Novosyadlyy, R.3    Gallagher, E.J.4    Scheinman, E.J.5
  • 58
    • 77449153137 scopus 로고    scopus 로고
    • Dual action of apolipoprotein E-interacting HCCR-1 oncoprotein and its implication for breast cancer and obesity
    • Ha SA, Shin SM, Kim HK, Kim S, Namkoong H, et al. (2009) Dual action of apolipoprotein E-interacting HCCR-1 oncoprotein and its implication for breast cancer and obesity. J Cell Mol Med 13: 3868-3675.
    • (2009) J Cell Mol Med , vol.13 , pp. 3675-3868
    • Ha, S.A.1    Shin, S.M.2    Kim, H.K.3    Kim, S.4    Namkoong, H.5
  • 59
    • 58549096553 scopus 로고    scopus 로고
    • Apolipoprotein E4 allele influences the response of plasma triglyceride levels to tamoxifen in breast cancer patients
    • Chang NW, Chen FN, Wu CT, Lin CF, Chen DR, (2009) Apolipoprotein E4 allele influences the response of plasma triglyceride levels to tamoxifen in breast cancer patients. Clin Chim Acta 401: 144-147.
    • (2009) Clin Chim Acta , vol.401 , pp. 144-147
    • Chang, N.W.1    Chen, F.N.2    Wu, C.T.3    Lin, C.F.4    Chen, D.R.5
  • 61
    • 79955965569 scopus 로고    scopus 로고
    • Aging Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan
    • Kulminski AM, Culminskaya I, Ukraintseva SV, Arbeev KG, Arbeeva L, et al. (2011) Aging Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. Aging Cell 10: 533-541.
    • (2011) Aging Cell , vol.10 , pp. 533-541
    • Kulminski, A.M.1    Culminskaya, I.2    Ukraintseva, S.V.3    Arbeev, K.G.4    Arbeeva, L.5
  • 62
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule HD, Maloney TM, Wolman SR, Peterson WD Jr, Brenz R, et al. (1990) Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 50: 6075-6086.
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3    Peterson Jr., W.D.4    Brenz, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.