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Volumn 75, Issue , 2014, Pages 255-269

Carbonic anhydrase IX (CAIX) as a mediator of hypoxia-induced stress response in cancer cells

Author keywords

Enzymatic activity; Hypoxia; Metastasis; Therapeutic targe; Tumor growth

Indexed keywords

CA9 PROTEIN, HUMAN; CARBON DIOXIDE; CARBONATE DEHYDRATASE; TUMOR ANTIGEN;

EID: 84899771418     PISSN: 03060225     EISSN: None     Source Type: Journal    
DOI: 10.1007/978-94-007-7359-2_13     Document Type: Article
Times cited : (67)

References (42)
  • 2
    • 70450223507 scopus 로고    scopus 로고
    • Generating specificity and diversity in the transcriptional response to hypoxia
    • Lendahl U, Lee KL, Yang H, Poellinger L (2009) Generating specificity and diversity in the transcriptional response to hypoxia. Nat Rev Genet 10:821–832
    • (2009) Nat Rev Genet , vol.10 , pp. 821-832
    • Lendahl, U.1    Lee, K.L.2    Yang, H.3    Poellinger, L.4
  • 3
    • 46749121459 scopus 로고    scopus 로고
    • Causes and consequences of increased glucose metabolism of cancers
    • Gillies RJ, Robey I, Gatenby RA (2008) Causes and consequences of increased glucose metabolism of cancers. J Nucl Med 49(Suppl 2):24S–42S
    • (2008) J Nucl Med , vol.49 , pp. 24S-42S
    • Gillies, R.J.1    Robey, I.2    Gatenby, R.A.3
  • 5
    • 62749124795 scopus 로고    scopus 로고
    • Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?
    • Kaluz S, Kaluzova M, Liao SY, Lerman M, Stanbridge EJ (2009) Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: a one transcription factor (HIF-1) show? Biochim Biophys Acta 1795:162–172
    • (2009) Biochim Biophys Acta , vol.1795 , pp. 162-172
    • Kaluz, S.1    Kaluzova, M.2    Liao, S.Y.3    Lerman, M.4    Stanbridge, E.J.5
  • 6
    • 84859870939 scopus 로고    scopus 로고
    • Recent developments in targeting carbonic anhydrase IX for cancer therapeutics
    • McDonald PC, Winum JY, Supuran CT, Dedhar S (2012) Recent developments in targeting carbonic anhydrase IX for cancer therapeutics. Oncotarget 3:84–97
    • (2012) Oncotarget , vol.3 , pp. 84-97
    • McDonald, P.C.1    Winum, J.Y.2    Supuran, C.T.3    Dedhar, S.4
  • 7
    • 84874532245 scopus 로고    scopus 로고
    • Carbonic anhydrase IX as a target for metastatic disease
    • Gieling RG, Williams KJ (2013) Carbonic anhydrase IX as a target for metastatic disease. Bioorg Med Chem 21:1470–1476
    • (2013) Bioorg Med Chem , vol.21 , pp. 1470-1476
    • Gieling, R.G.1    Williams, K.J.2
  • 8
    • 80053563164 scopus 로고    scopus 로고
    • Interfering with pH regulation in tumours as a therapeutic strategy
    • Neri D, Supuran CT (2011) Interfering with pH regulation in tumours as a therapeutic strategy. Nat Rev Drug Discov 10:767–777
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 767-777
    • Neri, D.1    Supuran, C.T.2
  • 9
    • 79957534572 scopus 로고    scopus 로고
    • Targeting hypoxia in cancer therapy
    • Wilson WR, Hay MP (2011) Targeting hypoxia in cancer therapy. Nat Rev Cancer 11:393–410
    • (2011) Nat Rev Cancer , vol.11 , pp. 393-410
    • Wilson, W.R.1    Hay, M.P.2
  • 10
    • 84867818496 scopus 로고    scopus 로고
    • Inhibition of carbonic anhydrase IX as a novel anticancer mechanism
    • Supuran CT (2012) Inhibition of carbonic anhydrase IX as a novel anticancer mechanism. World J Clin Oncol 3:98–103
    • (2012) World J Clin Oncol , vol.3 , pp. 98-103
    • Supuran, C.T.1
  • 11
    • 38849143765 scopus 로고    scopus 로고
    • Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
    • Supuran CT (2008) Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 7:168–181
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 168-181
    • Supuran, C.T.1
  • 13
    • 58249094845 scopus 로고    scopus 로고
    • Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
    • Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouyssegur J (2009) Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69:358–368
    • (2009) Cancer Res , vol.69 , pp. 358-368
    • Chiche, J.1    Ilc, K.2    Laferriere, J.3    Trottier, E.4    Dayan, F.5    Mazure, N.M.6    Brahimi-Horn, M.C.7    Pouyssegur, J.8
  • 15
    • 84877624475 scopus 로고    scopus 로고
    • Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis
    • Doyen J, Parks SK, Marcie S, Pouyssegur J, Chiche J (2012) Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis. Front Oncol 2:199
    • (2012) Front Oncol , vol.2 , pp. 199
    • Doyen, J.1    Parks, S.K.2    Marcie, S.3    Pouyssegur, J.4    Chiche, J.5
  • 16
    • 67651091693 scopus 로고    scopus 로고
    • In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives
    • Ahlskog JK, Dumelin CE, Trussel S, Marlind J, Neri D (2009) In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives. Bioorg Med Chem Lett 19:4851–4856
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 4851-4856
    • Ahlskog, J.K.1    Dumelin, C.E.2    Trussel, S.3    Marlind, J.4    Neri, D.5
  • 17
    • 69949128698 scopus 로고    scopus 로고
    • Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model
    • Dubois L, Lieuwes NG, Maresca A, Thiry A, Supuran CT, Scozzafava A, Wouters BG, Lambin P (2009) Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model. Radiother Oncol 92:423–428
    • (2009) Radiother Oncol , vol.92 , pp. 423-428
    • Dubois, L.1    Lieuwes, N.G.2    Maresca, A.3    Thiry, A.4    Supuran, C.T.5    Scozzafava, A.6    Wouters, B.G.7    Lambin, P.8
  • 20
    • 79952808077 scopus 로고    scopus 로고
    • Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis
    • Pacchiano F, Carta F, McDonald PC, Lou Y, Vullo D, Scozzafava A, Dedhar S, Supuran CT (2011) Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis. J Med Chem 54:1896–1902
    • (2011) J Med Chem , vol.54 , pp. 1896-1902
    • Pacchiano, F.1    Carta, F.2    McDonald, P.C.3    Lou, Y.4    Vullo, D.5    Scozzafava, A.6    Dedhar, S.7    Supuran, C.T.8
  • 23
  • 24
    • 78649659788 scopus 로고    scopus 로고
    • PH control mechanisms of tumor survival and growth
    • Parks SK, Chiche J, Pouyssegur J (2011) pH control mechanisms of tumor survival and growth. J Cell Physiol 226:299–308
    • (2011) J Cell Physiol , vol.226 , pp. 299-308
    • Parks, S.K.1    Chiche, J.2    Pouyssegur, J.3
  • 25
    • 37549013776 scopus 로고    scopus 로고
    • A microenvironmental model of carcinogenesis
    • Gatenby RA, Gillies RJ (2008) A microenvironmental model of carcinogenesis. Nat Rev Cancer 8:56–61
    • (2008) Nat Rev Cancer , vol.8 , pp. 56-61
    • Gatenby, R.A.1    Gillies, R.J.2
  • 26
    • 78650308850 scopus 로고    scopus 로고
    • New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
    • Swietach P, Hulikova A, Vaughan-Jones RD, Harris AL (2010) New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation. Oncogene 29:6509–6521
    • (2010) Oncogene , vol.29 , pp. 6509-6521
    • Swietach, P.1    Hulikova, A.2    Vaughan-Jones, R.D.3    Harris, A.L.4
  • 27
    • 4344699403 scopus 로고    scopus 로고
    • Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion
    • Robertson N, Potter C, Harris AL (2004) Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Res 64:6160–6165
    • (2004) Cancer Res , vol.64 , pp. 6160-6165
    • Robertson, N.1    Potter, C.2    Harris, A.L.3
  • 28
    • 67649970841 scopus 로고    scopus 로고
    • Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells
    • Li Y, Wang H, Oosterwijk E, Tu C, Shiverick KT, Silverman DN, Frost SC (2009) Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells. Cancer Invest 27:613–623
    • (2009) Cancer Invest , vol.27 , pp. 613-623
    • Li, Y.1    Wang, H.2    Oosterwijk, E.3    Tu, C.4    Shiverick, K.T.5    Silverman, D.N.6    Frost, S.C.7
  • 34
    • 79953138420 scopus 로고    scopus 로고
    • Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion
    • Shin HJ, Rho SB, Jung DC, Han IO, Oh ES, Kim JY (2011) Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion. J Cell Sci 124:1077–1087
    • (2011) J Cell Sci , vol.124 , pp. 1077-1087
    • Shin, H.J.1    Rho, S.B.2    Jung, D.C.3    Han, I.O.4    Oh, E.S.5    Kim, J.Y.6
  • 36
    • 84878782832 scopus 로고    scopus 로고
    • Carbonic anhydrase IX: A hypoxia-controlled “catalyst” of cell migration
    • Svastova E, Pastorekova S (2013) Carbonic anhydrase IX: a hypoxia-controlled “catalyst” of cell migration. Cell Adh Migr 7:226–231
    • (2013) Cell Adh Migr , vol.7 , pp. 226-231
    • Svastova, E.1    Pastorekova, S.2
  • 40
    • 84873727788 scopus 로고    scopus 로고
    • Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: Relationships with markers of tumor hypoxia and microvascularity
    • Currie MJ, Beardsley BE, Harris GC, Gunningham SP, Dachs GU, Dijkstra B, Morrin HR, Wells JE, Robinson BA (2013) Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity. Hum Pathol 44:402–411
    • (2013) Hum Pathol , vol.44 , pp. 402-411
    • Currie, M.J.1    Beardsley, B.E.2    Harris, G.C.3    Gunningham, S.P.4    Dachs, G.U.5    Dijkstra, B.6    Morrin, H.R.7    Wells, J.E.8    Robinson, B.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.