In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 16, 2009, Pages 4851-4856

  Ahlskog, Julia K J ^a   Dumelin, Christoph E ^a   Trüssel, Sabrina ^a   Mårlind, Jessica ^a   Neri, Dario ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Acetazolamide; CA IX; CA XII; Carbonic anhydrase; Tumor targeting

Indexed keywords

2 (6 HYDROXY 3 OXO 3H XANTHEN 9 YL) 5 (5 SULFAMOYL 1,3,4 THIADIAZOL 2 YLCARBAMOYL)BENZOIC ACID; 6 [4 (4 IODOPHENYL)BUTANAMIDO] 2 [4 OXO 4 (5 SULFAMOYL 1,3,4 THIADIAZOL 2 YLAMINO)BUTANAMIDO]HEXANOIC ACID; ACETAZOLAMIDE; ALBUMIN; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; FLUOROURACIL; SUNITINIB; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG SYNTHESIS; DRUG TARGETING; DRUG TOLERABILITY; ENZYME BINDING; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN BINDING; XENOGRAFT;

ACETAMIDES; ANIMALS; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FLUORESCENT DYES; HUMANS; MICE; MICE, NUDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67651091693     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.022     Document Type: Article

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