-
1
-
-
0018894860
-
The permeability of endplate channels to monovalent and divalent metal cations
-
Adams D.J., Dwyer T.M., Hille B. The permeability of endplate channels to monovalent and divalent metal cations. J. Gen. Physiol. 1980, 75:493-510.
-
(1980)
J. Gen. Physiol.
, vol.75
, pp. 493-510
-
-
Adams, D.J.1
Dwyer, T.M.2
Hille, B.3
-
2
-
-
79251476558
-
Pharmacology of structural changes at the GABA(A) receptor transmitter binding site
-
Akk G., Li P., Bracamontes J., Wang M., Steinbach J.H. Pharmacology of structural changes at the GABA(A) receptor transmitter binding site. Br. J. Pharmacol. 2011, 162:840-850.
-
(2011)
Br. J. Pharmacol.
, vol.162
, pp. 840-850
-
-
Akk, G.1
Li, P.2
Bracamontes, J.3
Wang, M.4
Steinbach, J.H.5
-
3
-
-
58249113980
-
Mammalian nicotinic acetylcholine receptors: from structure to function
-
Albuquerque E.X., Pereira E.F.R., Alkondon M., Rogers S.W. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev. 2009, 89:73-120.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 73-120
-
-
Albuquerque, E.X.1
Pereira, E.F.R.2
Alkondon, M.3
Rogers, S.W.4
-
4
-
-
84906568725
-
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
-
Althoff T., Hibbs R.E., Banerjee S., Gouaux E. X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature 2014, 512:333-337.
-
(2014)
Nature
, vol.512
, pp. 333-337
-
-
Althoff, T.1
Hibbs, R.E.2
Banerjee, S.3
Gouaux, E.4
-
7
-
-
84855175213
-
Thinking in cycles: MWC is a good model for acetylcholine receptor-channels
-
Auerbach A. Thinking in cycles: MWC is a good model for acetylcholine receptor-channels. J. Physiol. 2012, 590:93-98.
-
(2012)
J. Physiol.
, vol.590
, pp. 93-98
-
-
Auerbach, A.1
-
8
-
-
0031870973
-
Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism
-
Auerbach A., Akk G. Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism. J. Gen. Physiol. 1998, 112:181-197.
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 181-197
-
-
Auerbach, A.1
Akk, G.2
-
9
-
-
84890882915
-
Localization of glycine receptors in the human forebrain, brainstem, and cervical spinal cord: an immunohistochemical review
-
Baer K., Waldvogel H.J., Faull R.L.M., Rees M.I. Localization of glycine receptors in the human forebrain, brainstem, and cervical spinal cord: an immunohistochemical review. Front. Mol. Neurosci. 2009, 2:25.
-
(2009)
Front. Mol. Neurosci.
, vol.2
, pp. 25
-
-
Baer, K.1
Waldvogel, H.J.2
Faull, R.L.M.3
Rees, M.I.4
-
10
-
-
84987677320
-
Cell-surface translational dynamics of nicotinic acetylcholine receptors
-
Barrantes F.J. Cell-surface translational dynamics of nicotinic acetylcholine receptors. Front. Synaptic Neurosci. 2014, 6:25.
-
(2014)
Front. Synaptic Neurosci.
, vol.6
, pp. 25
-
-
Barrantes, F.J.1
-
11
-
-
0025313553
-
The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon
-
Beeson D., Morris A., Vincent A., Newsom-Davis J. The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon. EMBO J. 1990, 9:2101-2106.
-
(1990)
EMBO J.
, vol.9
, pp. 2101-2106
-
-
Beeson, D.1
Morris, A.2
Vincent, A.3
Newsom-Davis, J.4
-
12
-
-
84864486886
-
MOLEonline 2.0: interactive web-based analysis of biomacromolecular channels
-
Berka K., Hanák O., Sehnal D., Banás P., Navrátilová V., Jaiswal D., Ionescu C.-M., Svobodová Vareková R., Koca J., Otyepka M. MOLEonline 2.0: interactive web-based analysis of biomacromolecular channels. Nucleic Acids Res. 2012, 40:W222-W227.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. W222-W227
-
-
Berka, K.1
Hanák, O.2
Sehnal, D.3
Banás, P.4
Navrátilová, V.5
Jaiswal, D.6
Ionescu, C.-M.7
Svobodová Vareková, R.8
Koca, J.9
Otyepka, M.10
-
13
-
-
44449105649
-
Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein
-
Bertaccini E.J., Lindahl E., Sixma T., Trudell J.R. Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein. J. Chem. Inf. Model. 2008, 48:855-860.
-
(2008)
J. Chem. Inf. Model.
, vol.48
, pp. 855-860
-
-
Bertaccini, E.J.1
Lindahl, E.2
Sixma, T.3
Trudell, J.R.4
-
14
-
-
34548677767
-
Allosteric modulation of nicotinic acetylcholine receptors
-
Bertrand D., Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors. Biochem. Pharmacol. 2007, 74:1155-1163.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 1155-1163
-
-
Bertrand, D.1
Gopalakrishnan, M.2
-
15
-
-
33745033309
-
Glycine receptors: recent insights into their structural organization and functional diversity
-
Betz H., Laube B. Glycine receptors: recent insights into their structural organization and functional diversity. J. Neurochem. 2006, 97:1600-1610.
-
(2006)
J. Neurochem.
, vol.97
, pp. 1600-1610
-
-
Betz, H.1
Laube, B.2
-
16
-
-
84861866747
-
Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein
-
Billen B., Spurny R., Brams M., van Elk R., Valera-Kummer S., Yakel J.L., Voets T., Bertrand D., Smit A.B., Ulens C. Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein. Proc. Natl. Acad. Sci. USA 2012, 109:9173-9178.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9173-9178
-
-
Billen, B.1
Spurny, R.2
Brams, M.3
van Elk, R.4
Valera-Kummer, S.5
Yakel, J.L.6
Voets, T.7
Bertrand, D.8
Smit, A.B.9
Ulens, C.10
-
17
-
-
33846106078
-
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
-
Bocquet N., Prado de Carvalho L., Cartaud J., Neyton J., Le Poupon C., Taly A., Grutter T., Changeux J.-P., Corringer P.-J. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature 2007, 445:116-119.
-
(2007)
Nature
, vol.445
, pp. 116-119
-
-
Bocquet, N.1
Prado de Carvalho, L.2
Cartaud, J.3
Neyton, J.4
Le Poupon, C.5
Taly, A.6
Grutter, T.7
Changeux, J.-P.8
Corringer, P.-J.9
-
18
-
-
58149267953
-
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
Bocquet N., Nury H., Baaden M., Le Poupon C., Changeux J.-P., Delarue M., Corringer P.-J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 2009, 457:111-114.
-
(2009)
Nature
, vol.457
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.-P.5
Delarue, M.6
Corringer, P.-J.7
-
19
-
-
84892181483
-
The impact of human hyperekplexia mutations on glycine receptor structure and function
-
Bode A., Lynch J.W. The impact of human hyperekplexia mutations on glycine receptor structure and function. Mol. Brain 2014, 7:2.
-
(2014)
Mol. Brain
, vol.7
, pp. 2
-
-
Bode, A.1
Lynch, J.W.2
-
20
-
-
0033564411
-
Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand
-
Boileau A.J., Evers A.R., Davis A.F., Czajkowski C. Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand. J. Neurosci. 1999, 19:4847-4854.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4847-4854
-
-
Boileau, A.J.1
Evers, A.R.2
Davis, A.F.3
Czajkowski, C.4
-
21
-
-
0028272914
-
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers
-
Bormann J., Rundström N., Betz H., Langosch D. Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers. EMBO J. 1994, 13:1493.
-
(1994)
EMBO J.
, vol.13
, pp. 1493
-
-
Bormann, J.1
Rundström, N.2
Betz, H.3
Langosch, D.4
-
22
-
-
77950547338
-
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
-
Bourne Y., Radić Z., Aráoz R., Talley T.T., Benoit E., Servent D., Taylor P., Molgó J., Marchot P. Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism. Proc. Natl. Acad. Sci. USA 2010, 107:6076-6081.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 6076-6081
-
-
Bourne, Y.1
Radić, Z.2
Aráoz, R.3
Talley, T.T.4
Benoit, E.5
Servent, D.6
Taylor, P.7
Molgó, J.8
Marchot, P.9
-
23
-
-
84861189283
-
New insights into the structural bases of activation of Cys-loop receptors
-
Bouzat C. New insights into the structural bases of activation of Cys-loop receptors. J. Physiol. Paris 2012, 106:23-33.
-
(2012)
J. Physiol. Paris
, vol.106
, pp. 23-33
-
-
Bouzat, C.1
-
24
-
-
84930531864
-
The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders
-
Braat S., Kooy R.F. The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders. Neuron 2015, 86:1119-1130.
-
(2015)
Neuron
, vol.86
, pp. 1119-1130
-
-
Braat, S.1
Kooy, R.F.2
-
25
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van Der Oost J., Smit A.B., Sixma T.K. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 2001, 411:269-276.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
26
-
-
84855729789
-
Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease
-
Brickley S.G., Mody I. Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease. Neuron 2012, 73:23-34.
-
(2012)
Neuron
, vol.73
, pp. 23-34
-
-
Brickley, S.G.1
Mody, I.2
-
27
-
-
0032446339
-
Molecular cloning of alternatively spliced human 5-HT3 receptor cDNAs
-
Brüss M., Göthert M., Hayer M., Bönisch H. Molecular cloning of alternatively spliced human 5-HT3 receptor cDNAs. Ann. N Y Acad. Sci. 1998, 861:234-235.
-
(1998)
Ann. N Y Acad. Sci.
, vol.861
, pp. 234-235
-
-
Brüss, M.1
Göthert, M.2
Hayer, M.3
Bönisch, H.4
-
28
-
-
84885775931
-
A gating mechanism of pentameric ligand-gated ion channels
-
Calimet N., Simoes M., Changeux J.-P., Karplus M., Taly A., Cecchini M. A gating mechanism of pentameric ligand-gated ion channels. Proc. Natl. Acad. Sci. USA 2013, 110:E3987-E3996.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E3987-E3996
-
-
Calimet, N.1
Simoes, M.2
Changeux, J.-P.3
Karplus, M.4
Taly, A.5
Cecchini, M.6
-
29
-
-
84893705363
-
Acute activation, desensitization and smoldering activation of human acetylcholine receptors
-
Campling B.G., Kuryatov A., Lindstrom J. Acute activation, desensitization and smoldering activation of human acetylcholine receptors. PLoS ONE 2013, 8:e79653.
-
(2013)
PLoS ONE
, vol.8
, pp. e79653
-
-
Campling, B.G.1
Kuryatov, A.2
Lindstrom, J.3
-
30
-
-
84887104777
-
Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor
-
Carland J.E., Cooper M.A., Livesey M.R., Hales T.G., Peters J.A., Lambert J.J. Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor. J. Biol. Chem. 2013, 288:31592-31601.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31592-31601
-
-
Carland, J.E.1
Cooper, M.A.2
Livesey, M.R.3
Hales, T.G.4
Peters, J.A.5
Lambert, J.J.6
-
31
-
-
0015788764
-
Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata
-
Cartaud J., Benedetti E.L., Cohen J.B., Meunier J.C., Changeux J.-P. Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata. FEBS Lett. 1973, 33:109-113.
-
(1973)
FEBS Lett.
, vol.33
, pp. 109-113
-
-
Cartaud, J.1
Benedetti, E.L.2
Cohen, J.B.3
Meunier, J.C.4
Changeux, J.-P.5
-
32
-
-
84932197999
-
The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation
-
Cecchini M., Changeux J.-P. The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation. Neuropharmacology 2015, 96(Pt B):137-149.
-
(2015)
Neuropharmacology
, vol.96
, pp. 137-149
-
-
Cecchini, M.1
Changeux, J.-P.2
-
33
-
-
11844258265
-
A speed limit for conformational change of an allosteric membrane protein
-
Chakrapani S., Auerbach A. A speed limit for conformational change of an allosteric membrane protein. Proc. Natl. Acad. Sci. USA 2005, 102:87-92.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 87-92
-
-
Chakrapani, S.1
Auerbach, A.2
-
34
-
-
0032728861
-
Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine
-
Chang Y., Weiss D.S. Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine. Biophys. J. 1999, 77:2542-2551.
-
(1999)
Biophys. J.
, vol.77
, pp. 2542-2551
-
-
Chang, Y.1
Weiss, D.S.2
-
35
-
-
0014936960
-
[Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine]
-
Changeux J.-P., Kasai M., Huchet M., Meunier J.C. [Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine]. C. R. Acad. Sci. Hebd. Seances Acad. Sci. D 1970, 270:2864-2867.
-
(1970)
C. R. Acad. Sci. Hebd. Seances Acad. Sci. D
, vol.270
, pp. 2864-2867
-
-
Changeux, J.-P.1
Kasai, M.2
Huchet, M.3
Meunier, J.C.4
-
36
-
-
84892566635
-
Photoaffinity labeling the propofol binding site in GLIC
-
Chiara D.C., Gill J.F., Chen Q., Tillman T., Dailey W.P., Eckenhoff R.G., Xu Y., Tang P., Cohen J.B. Photoaffinity labeling the propofol binding site in GLIC. Biochemistry 2014, 53:135-142.
-
(2014)
Biochemistry
, vol.53
, pp. 135-142
-
-
Chiara, D.C.1
Gill, J.F.2
Chen, Q.3
Tillman, T.4
Dailey, W.P.5
Eckenhoff, R.G.6
Xu, Y.7
Tang, P.8
Cohen, J.B.9
-
37
-
-
84879252425
-
Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor
-
Christian C.A., Herbert A.G., Holt R.L., Peng K., Sherwood K.D., Pangratz-Fuehrer S., Rudolph U., Huguenard J.R. Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor. Neuron 2013, 78:1063-1074.
-
(2013)
Neuron
, vol.78
, pp. 1063-1074
-
-
Christian, C.A.1
Herbert, A.G.2
Holt, R.L.3
Peng, K.4
Sherwood, K.D.5
Pangratz-Fuehrer, S.6
Rudolph, U.7
Huguenard, J.R.8
-
38
-
-
84904301809
-
International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands
-
Christopoulos A., Changeux J.-P., Catterall W.A., Fabbro D., Burris T.P., Cidlowski J.A., Olsen R.W., Peters J.A., Neubig R.R., Pin J.-P., et al. International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands. Pharmacol. Rev. 2014, 66:918-947.
-
(2014)
Pharmacol. Rev.
, vol.66
, pp. 918-947
-
-
Christopoulos, A.1
Changeux, J.-P.2
Catterall, W.A.3
Fabbro, D.4
Burris, T.P.5
Cidlowski, J.A.6
Olsen, R.W.7
Peters, J.A.8
Neubig, R.R.9
Pin, J.-P.10
-
39
-
-
0032032840
-
From muscle endplate to brain synapses: a short history of synapses and agonist-activated ion channels
-
Colquhoun D., Sakmann B. From muscle endplate to brain synapses: a short history of synapses and agonist-activated ion channels. Neuron 1998, 20:381-387.
-
(1998)
Neuron
, vol.20
, pp. 381-387
-
-
Colquhoun, D.1
Sakmann, B.2
-
40
-
-
0033119869
-
Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor
-
Corringer P.J., Bertrand S., Galzi J.L., Devillers-Thiéry A., Changeux J.-P., Bertrand D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron 1999, 22:831-843.
-
(1999)
Neuron
, vol.22
, pp. 831-843
-
-
Corringer, P.J.1
Bertrand, S.2
Galzi, J.L.3
Devillers-Thiéry, A.4
Changeux, J.-P.5
Bertrand, D.6
-
41
-
-
84861963413
-
Structure and pharmacology of pentameric receptor channels: from bacteria to brain
-
Corringer P.-J., Poitevin F., Prevost M.S., Sauguet L., Delarue M., Changeux J.-P. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure 2012, 20:941-956.
-
(2012)
Structure
, vol.20
, pp. 941-956
-
-
Corringer, P.-J.1
Poitevin, F.2
Prevost, M.S.3
Sauguet, L.4
Delarue, M.5
Changeux, J.-P.6
-
42
-
-
0025605864
-
A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX
-
Couturier S., Bertrand D., Matter J.M., Hernandez M.C., Bertrand S., Millar N., Valera S., Barkas T., Ballivet M. A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron 1990, 5:847-856.
-
(1990)
Neuron
, vol.5
, pp. 847-856
-
-
Couturier, S.1
Bertrand, D.2
Matter, J.M.3
Hernandez, M.C.4
Bertrand, S.5
Millar, N.6
Valera, S.7
Barkas, T.8
Ballivet, M.9
-
43
-
-
0025890013
-
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina
-
Cutting G.R., Lu L., O'Hara B.F., Kasch L.M., Montrose-Rafizadeh C., Donovan D.M., Shimada S., Antonarakis S.E., Guggino W.B., Uhl G.R., et al. Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina. Proc. Natl. Acad. Sci. USA 1991, 88:2673-2677.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2673-2677
-
-
Cutting, G.R.1
Lu, L.2
O'Hara, B.F.3
Kasch, L.M.4
Montrose-Rafizadeh, C.5
Donovan, D.M.6
Shimada, S.7
Antonarakis, S.E.8
Guggino, W.B.9
Uhl, G.R.10
-
44
-
-
84870378961
-
The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors
-
Cymes G.D., Grosman C. The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors. Nat. Chem. Biol. 2012, 8:975-981.
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 975-981
-
-
Cymes, G.D.1
Grosman, C.2
-
45
-
-
30744470883
-
Probing ion-channel pores one proton at a time
-
Cymes G.D., Ni Y., Grosman C. Probing ion-channel pores one proton at a time. Nature 2005, 438:975-980.
-
(2005)
Nature
, vol.438
, pp. 975-980
-
-
Cymes, G.D.1
Ni, Y.2
Grosman, C.3
-
46
-
-
84886530690
-
A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors
-
daCosta C.J.B., Dey L., Therien J.P.D., Baenziger J.E. A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors. Nat. Chem. Biol. 2013, 9:701-707.
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 701-707
-
-
daCosta, C.J.B.1
Dey, L.2
Therien, J.P.D.3
Baenziger, J.E.4
-
47
-
-
0033611396
-
The 5-HT3B subunit is a major determinant of serotonin-receptor function
-
Davies P.A., Pistis M., Hanna M.C., Peters J.A., Lambert J.J., Hales T.G., Kirkness E.F. The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature 1999, 397:359-363.
-
(1999)
Nature
, vol.397
, pp. 359-363
-
-
Davies, P.A.1
Pistis, M.2
Hanna, M.C.3
Peters, J.A.4
Lambert, J.J.5
Hales, T.G.6
Kirkness, E.F.7
-
48
-
-
79959877467
-
Reward, addiction, withdrawal to nicotine
-
De Biasi M., Dani J.A. Reward, addiction, withdrawal to nicotine. Annu. Rev. Neurosci. 2011, 34:105-130.
-
(2011)
Annu. Rev. Neurosci.
, vol.34
, pp. 105-130
-
-
De Biasi, M.1
Dani, J.A.2
-
49
-
-
0005575307
-
On the localization of acetylcholine receptors
-
Del Castillo J., Katz B. On the localization of acetylcholine receptors. J. Physiol. 1955, 128:157-181.
-
(1955)
J. Physiol.
, vol.128
, pp. 157-181
-
-
Del Castillo, J.1
Katz, B.2
-
50
-
-
34547520128
-
Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution
-
Dellisanti C.D., Yao Y., Stroud J.C., Wang Z.-Z., Chen L. Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution. Nat. Neurosci. 2007, 10:953-962.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 953-962
-
-
Dellisanti, C.D.1
Yao, Y.2
Stroud, J.C.3
Wang, Z.-Z.4
Chen, L.5
-
51
-
-
79958053071
-
The evolution of pentameric ligand-gated ion channels
-
Dent J.A. The evolution of pentameric ligand-gated ion channels. Adv. Exp. Med. Biol. 2010, 683:11-23.
-
(2010)
Adv. Exp. Med. Biol.
, vol.683
, pp. 11-23
-
-
Dent, J.A.1
-
52
-
-
48249102000
-
Phylogeny.fr: robust phylogenetic analysis for the non-specialist
-
Dereeper A., Guignon V., Blanc G., Audic S., Buffet S., Chevenet F., Dufayard J.-F., Guindon S., Lefort V., Lescot M., et al. Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res. 2008, 36:W465-W469.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. W465-W469
-
-
Dereeper, A.1
Guignon, V.2
Blanc, G.3
Audic, S.4
Buffet, S.5
Chevenet, F.6
Dufayard, J.-F.7
Guindon, S.8
Lefort, V.9
Lescot, M.10
-
53
-
-
84949034076
-
Pathways and Barriers for Ion Translocation through the 5-HT3A Receptor Channel
-
Di Maio D., Chandramouli B., Brancato G. Pathways and Barriers for Ion Translocation through the 5-HT3A Receptor Channel. PLoS ONE 2015, 10:e0140258.
-
(2015)
PLoS ONE
, vol.10
, pp. e0140258
-
-
Di Maio, D.1
Chandramouli, B.2
Brancato, G.3
-
54
-
-
84922216722
-
Nicotinic ACh receptors as therapeutic targets in CNS disorders
-
Dineley K.T., Pandya A.A., Yakel J.L. Nicotinic ACh receptors as therapeutic targets in CNS disorders. Trends Pharmacol. Sci. 2015, 36:96-108.
-
(2015)
Trends Pharmacol. Sci.
, vol.36
, pp. 96-108
-
-
Dineley, K.T.1
Pandya, A.A.2
Yakel, J.L.3
-
55
-
-
84944273234
-
Glycine receptor mechanism elucidated by electron cryo-microscopy
-
Du J., Lü W., Wu S., Cheng Y., Gouaux E. Glycine receptor mechanism elucidated by electron cryo-microscopy. Nature 2015, 526:224-229.
-
(2015)
Nature
, vol.526
, pp. 224-229
-
-
Du, J.1
Lü, W.2
Wu, S.3
Cheng, Y.4
Gouaux, E.5
-
56
-
-
79961044901
-
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family
-
Duret G., Van Renterghem C., Weng Y., Prevost M., Moraga-Cid G., Huon C., Sonner J.M., Corringer P.-J. Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family. Proc. Natl. Acad. Sci. USA 2011, 108:12143-12148.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 12143-12148
-
-
Duret, G.1
Van Renterghem, C.2
Weng, Y.3
Prevost, M.4
Moraga-Cid, G.5
Huon, C.6
Sonner, J.M.7
Corringer, P.-J.8
-
57
-
-
77952682080
-
Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors
-
Edelstein S.J., Changeux J.-P. Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors. Biophys. J. 2010, 98:2045-2052.
-
(2010)
Biophys. J.
, vol.98
, pp. 2045-2052
-
-
Edelstein, S.J.1
Changeux, J.-P.2
-
58
-
-
0030281174
-
A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions
-
Edelstein S.J., Schaad O., Henry E., Bertrand D., Changeux J.-P. A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions. Biol. Cybern. 1996, 75:361-379.
-
(1996)
Biol. Cybern.
, vol.75
, pp. 361-379
-
-
Edelstein, S.J.1
Schaad, O.2
Henry, E.3
Bertrand, D.4
Changeux, J.-P.5
-
59
-
-
0027772476
-
Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities
-
Eiselé J.L., Bertrand S., Galzi J.L., Devillers-Thiéry A., Changeux J.-P., Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature 1993, 366:479-483.
-
(1993)
Nature
, vol.366
, pp. 479-483
-
-
Eiselé, J.L.1
Bertrand, S.2
Galzi, J.L.3
Devillers-Thiéry, A.4
Changeux, J.-P.5
Bertrand, D.6
-
60
-
-
0036623799
-
Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels
-
Elenes S., Auerbach A. Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels. J. Physiol. 2002, 541:367-383.
-
(2002)
J. Physiol.
, vol.541
, pp. 367-383
-
-
Elenes, S.1
Auerbach, A.2
-
61
-
-
0028171296
-
Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
-
Elgoyhen A.B., Johnson D.S., Boulter J., Vetter D.E., Heinemann S. Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 1994, 79:705-715.
-
(1994)
Cell
, vol.79
, pp. 705-715
-
-
Elgoyhen, A.B.1
Johnson, D.S.2
Boulter, J.3
Vetter, D.E.4
Heinemann, S.5
-
62
-
-
0035852933
-
Alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells
-
Elgoyhen A.B., Vetter D.E., Katz E., Rothlin C.V., Heinemann S.F., Boulter J. alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. Proc. Natl. Acad. Sci. USA 2001, 98:3501-3506.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3501-3506
-
-
Elgoyhen, A.B.1
Vetter, D.E.2
Katz, E.3
Rothlin, C.V.4
Heinemann, S.F.5
Boulter, J.6
-
63
-
-
84932193678
-
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors
-
Forman S.A., Chiara D.C., Miller K.W. Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors. Neuropharmacology 2015, 96(Pt B):169-177.
-
(2015)
Neuropharmacology
, vol.96
, pp. 169-177
-
-
Forman, S.A.1
Chiara, D.C.2
Miller, K.W.3
-
65
-
-
42349089480
-
General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal
-
Franks N.P. General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal. Nat. Rev. Neurosci. 2008, 9:370-386.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 370-386
-
-
Franks, N.P.1
-
66
-
-
84901688723
-
GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system
-
Fritschy J.-M., Panzanelli P. GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system. Eur. J. Neurosci. 2014, 39:1845-1865.
-
(2014)
Eur. J. Neurosci.
, vol.39
, pp. 1845-1865
-
-
Fritschy, J.-M.1
Panzanelli, P.2
-
67
-
-
42749089832
-
Gephyrin: where do we stand, where do we go?
-
Fritschy J.-M., Harvey R.J., Schwarz G. Gephyrin: where do we stand, where do we go?. Trends Neurosci. 2008, 31:257-264.
-
(2008)
Trends Neurosci.
, vol.31
, pp. 257-264
-
-
Fritschy, J.-M.1
Harvey, R.J.2
Schwarz, G.3
-
68
-
-
0026656037
-
Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic
-
Galzi J.L., Devillers-Thiéry A., Hussy N., Bertrand S., Changeux J.-P., Bertrand D. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature 1992, 359:500-505.
-
(1992)
Nature
, vol.359
, pp. 500-505
-
-
Galzi, J.L.1
Devillers-Thiéry, A.2
Hussy, N.3
Bertrand, S.4
Changeux, J.-P.5
Bertrand, D.6
-
69
-
-
0029958046
-
Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor
-
Galzi J.L., Bertrand S., Corringer P.J., Changeux J.-P., Bertrand D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. EMBO J. 1996, 15:5824-5832.
-
(1996)
EMBO J.
, vol.15
, pp. 5824-5832
-
-
Galzi, J.L.1
Bertrand, S.2
Corringer, P.J.3
Changeux, J.-P.4
Bertrand, D.5
-
71
-
-
84928143338
-
The desensitization gate of inhibitory Cys-loop receptors
-
Gielen M., Thomas P., Smart T.G. The desensitization gate of inhibitory Cys-loop receptors. Nat. Commun. 2015, 6:6829.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6829
-
-
Gielen, M.1
Thomas, P.2
Smart, T.G.3
-
72
-
-
84922355484
-
Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects
-
Gill-Thind J.K., Dhankher P., D'Oyley J.M., Sheppard T.D., Millar N.S. Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects. J. Biol. Chem. 2015, 290:3552-3562.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 3552-3562
-
-
Gill-Thind, J.K.1
Dhankher, P.2
D'Oyley, J.M.3
Sheppard, T.D.4
Millar, N.S.5
-
73
-
-
0000791015
-
Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine
-
Giraudat J., Dennis M., Heidmann T., Chang J.Y., Changeux J.-P. Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine. Proc. Natl. Acad. Sci. USA 1986, 83:2719-2723.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 2719-2723
-
-
Giraudat, J.1
Dennis, M.2
Heidmann, T.3
Chang, J.Y.4
Changeux, J.-P.5
-
74
-
-
84887444038
-
Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography
-
Gonzalez-Gutierrez G., Cuello L.G., Nair S.K., Grosman C. Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc. Natl. Acad. Sci. USA 2013, 110:18716-18721.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18716-18721
-
-
Gonzalez-Gutierrez, G.1
Cuello, L.G.2
Nair, S.K.3
Grosman, C.4
-
75
-
-
80053407923
-
Engineering a prokaryotic Cys-loop receptor with a third functional domain
-
Goyal R., Salahudeen A.A., Jansen M. Engineering a prokaryotic Cys-loop receptor with a third functional domain. J. Biol. Chem. 2011, 286:34635-34642.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34635-34642
-
-
Goyal, R.1
Salahudeen, A.A.2
Jansen, M.3
-
76
-
-
0025095280
-
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
-
Grenningloh G., Schmieden V., Schofield P.R., Seeburg P.H., Siddique T., Mohandas T.K., Becker C.M., Betz H. Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes. EMBO J. 1990, 9:771-776.
-
(1990)
EMBO J.
, vol.9
, pp. 771-776
-
-
Grenningloh, G.1
Schmieden, V.2
Schofield, P.R.3
Seeburg, P.H.4
Siddique, T.5
Mohandas, T.K.6
Becker, C.M.7
Betz, H.8
-
77
-
-
14844323974
-
A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels
-
Grutter T., Prado de Carvalho L., Virginie D., Taly A., Fischer M., Changeux J.-P. A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. C. R. Biol. 2005, 328:223-234.
-
(2005)
C. R. Biol.
, vol.328
, pp. 223-234
-
-
Grutter, T.1
Prado de Carvalho, L.2
Virginie, D.3
Taly, A.4
Fischer, M.5
Changeux, J.-P.6
-
78
-
-
84905034989
-
Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites!
-
Hamouda A.K., Jayakar S.S., Chiara D.C., Cohen J.B. Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites!. J. Mol. Neurosci. 2014, 53:480-486.
-
(2014)
J. Mol. Neurosci.
, vol.53
, pp. 480-486
-
-
Hamouda, A.K.1
Jayakar, S.S.2
Chiara, D.C.3
Cohen, J.B.4
-
79
-
-
84886042433
-
Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site
-
Han L., Talwar S., Wang Q., Shan Q., Lynch J.W. Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site. ACS Chem. Neurosci. 2013, 4:1361-1370.
-
(2013)
ACS Chem. Neurosci.
, vol.4
, pp. 1361-1370
-
-
Han, L.1
Talwar, S.2
Wang, Q.3
Shan, Q.4
Lynch, J.W.5
-
80
-
-
34248598024
-
Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors
-
Hansen S.B., Taylor P. Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. J. Mol. Biol. 2007, 369:895-901.
-
(2007)
J. Mol. Biol.
, vol.369
, pp. 895-901
-
-
Hansen, S.B.1
Taylor, P.2
-
81
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen S.B., Sulzenbacher G., Huxford T., Marchot P., Taylor P., Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J. 2005, 24:3635-3646.
-
(2005)
EMBO J.
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
82
-
-
61349137676
-
An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance
-
Hansen S.B., Wang H.L., Taylor P., Sine S.M. An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance. J. Biol. Chem. 2008, 283:36066-36070.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 36066-36070
-
-
Hansen, S.B.1
Wang, H.L.2
Taylor, P.3
Sine, S.M.4
-
83
-
-
84906545550
-
X-ray structure of the mouse serotonin 5-HT3 receptor
-
Hassaine G., Deluz C., Grasso L., Wyss R., Tol M.B., Hovius R., Graff A., Stahlberg H., Tomizaki T., Desmyter A., et al. X-ray structure of the mouse serotonin 5-HT3 receptor. Nature 2014, 512:276-281.
-
(2014)
Nature
, vol.512
, pp. 276-281
-
-
Hassaine, G.1
Deluz, C.2
Grasso, L.3
Wyss, R.4
Tol, M.B.5
Hovius, R.6
Graff, A.7
Stahlberg, H.8
Tomizaki, T.9
Desmyter, A.10
-
84
-
-
0017831891
-
Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states
-
Heidmann T., Changeux J.P. Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states. Annu. Rev. Biochem. 1978, 47:317-357.
-
(1978)
Annu. Rev. Biochem.
, vol.47
, pp. 317-357
-
-
Heidmann, T.1
Changeux, J.P.2
-
85
-
-
0019327308
-
Interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata in the millisecond time range: resolution of an "intermediate" conformational transition and evidence for positive cooperative effects
-
Heidmann T., Changeux J.-P. Interaction of a fluorescent agonist with the membrane-bound acetylcholine receptor from Torpedo marmorata in the millisecond time range: resolution of an "intermediate" conformational transition and evidence for positive cooperative effects. Biochem. Biophys. Res. Commun. 1980, 97:889-896.
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.97
, pp. 889-896
-
-
Heidmann, T.1
Changeux, J.-P.2
-
86
-
-
0020476445
-
[Molecular model of the regulation of chemical synapse efficiency at the postsynaptic level]
-
Heidmann T., Changeux J.-P. [Molecular model of the regulation of chemical synapse efficiency at the postsynaptic level]. C. R. Seances Acad. Sci. III 1982, 295:665-670.
-
(1982)
C. R. Seances Acad. Sci. III
, vol.295
, pp. 665-670
-
-
Heidmann, T.1
Changeux, J.-P.2
-
87
-
-
79957953215
-
Principles of activation and permeation in an anion-selective Cys-loop receptor
-
Hibbs R.E., Gouaux E. Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature 2011, 474:54-60.
-
(2011)
Nature
, vol.474
, pp. 54-60
-
-
Hibbs, R.E.1
Gouaux, E.2
-
88
-
-
41149168686
-
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
-
Hilf R.J.C., Dutzler R. X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature 2008, 452:375-379.
-
(2008)
Nature
, vol.452
, pp. 375-379
-
-
Hilf, R.J.C.1
Dutzler, R.2
-
89
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
Hilf R.J.C., Dutzler R. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel. Nature 2009, 457:115-118.
-
(2009)
Nature
, vol.457
, pp. 115-118
-
-
Hilf, R.J.C.1
Dutzler, R.2
-
90
-
-
33751314737
-
Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites
-
Hosie A.M., Wilkins M.E., da Silva H.M.A., Smart T.G. Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 2006, 444:486-489.
-
(2006)
Nature
, vol.444
, pp. 486-489
-
-
Hosie, A.M.1
Wilkins, M.E.2
da Silva, H.M.A.3
Smart, T.G.4
-
91
-
-
79961056938
-
Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution
-
Howard R.J., Slesinger P.A., Davies D.L., Das J., Trudell J.R., Harris R.A. Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcohol. Clin. Exp. Res. 2011, 35:1561-1573.
-
(2011)
Alcohol. Clin. Exp. Res.
, vol.35
, pp. 1561-1573
-
-
Howard, R.J.1
Slesinger, P.A.2
Davies, D.L.3
Das, J.4
Trudell, J.R.5
Harris, R.A.6
-
92
-
-
70349445450
-
Identification and comparison of amorphous calcium carbonate-binding protein and acetylcholine-binding protein in the abalone, Haliotis discus hannai
-
Huang J., Wang H., Cui Y., Zhang G., Zheng G., Liu S., Xie L., Zhang R. Identification and comparison of amorphous calcium carbonate-binding protein and acetylcholine-binding protein in the abalone, Haliotis discus hannai. Mar. Biotechnol. (NY) 2009, 11:596-607.
-
(2009)
Mar. Biotechnol. (NY)
, vol.11
, pp. 596-607
-
-
Huang, J.1
Wang, H.2
Cui, Y.3
Zhang, G.4
Zheng, G.5
Liu, S.6
Xie, L.7
Zhang, R.8
-
93
-
-
84881515004
-
Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera
-
Huang S., Li S.-X., Bren N., Cheng K., Gomoto R., Chen L., Sine S.M. Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera. Biochem. J. 2013, 454:303-310.
-
(2013)
Biochem. J.
, vol.454
, pp. 303-310
-
-
Huang, S.1
Li, S.-X.2
Bren, N.3
Cheng, K.4
Gomoto, R.5
Chen, L.6
Sine, S.M.7
-
94
-
-
84944052478
-
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
-
Huang X., Chen H., Michelsen K., Schneider S., Shaffer P.L. Crystal structure of human glycine receptor-α3 bound to antagonist strychnine. Nature 2015, 526:277-280.
-
(2015)
Nature
, vol.526
, pp. 277-280
-
-
Huang, X.1
Chen, H.2
Michelsen, K.3
Schneider, S.4
Shaffer, P.L.5
-
95
-
-
0028962784
-
Genetic and environmental aspects of the role of nicotinic receptors in neurodegenerative disorders: emphasis on Alzheimer's disease and Parkinson's disease
-
James J.R., Nordberg A. Genetic and environmental aspects of the role of nicotinic receptors in neurodegenerative disorders: emphasis on Alzheimer's disease and Parkinson's disease. Behav. Genet. 1995, 25:149-159.
-
(1995)
Behav. Genet.
, vol.25
, pp. 149-159
-
-
James, J.R.1
Nordberg, A.2
-
96
-
-
84874766162
-
Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog
-
Jayakar S.S., Dailey W.P., Eckenhoff R.G., Cohen J.B. Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog. J. Biol. Chem. 2013, 288:6178-6189.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 6178-6189
-
-
Jayakar, S.S.1
Dailey, W.P.2
Eckenhoff, R.G.3
Cohen, J.B.4
-
97
-
-
0030025395
-
The impact of receptor desensitization on fast synaptic transmission
-
Jones M.V., Westbrook G.L. The impact of receptor desensitization on fast synaptic transmission. Trends Neurosci. 1996, 19:96-101.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 96-101
-
-
Jones, M.V.1
Westbrook, G.L.2
-
98
-
-
76549189603
-
The Measurement of Synaptic Delay, and the Time Course of Acetylcholine Release at the Neuromuscular Junction
-
Katz B., Miledi R. The Measurement of Synaptic Delay, and the Time Course of Acetylcholine Release at the Neuromuscular Junction. Proc. R. Soc. Lond. B Biol. Sci. 1965, 161:483-495.
-
(1965)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.161
, pp. 483-495
-
-
Katz, B.1
Miledi, R.2
-
99
-
-
0015795705
-
The binding of acetylcholine to receptors and its removal from the synaptic cleft
-
Katz B., Miledi R. The binding of acetylcholine to receptors and its removal from the synaptic cleft. J. Physiol. 1973, 231:549-574.
-
(1973)
J. Physiol.
, vol.231
, pp. 549-574
-
-
Katz, B.1
Miledi, R.2
-
100
-
-
84965075853
-
A study of the desensitization produced by acetylcholine at the motor end-plate
-
Katz B., Thesleff S. A study of the desensitization produced by acetylcholine at the motor end-plate. J. Physiol. 1957, 138:63-80.
-
(1957)
J. Physiol.
, vol.138
, pp. 63-80
-
-
Katz, B.1
Thesleff, S.2
-
101
-
-
0041806486
-
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
-
Kelley S.P., Dunlop J.I., Kirkness E.F., Lambert J.J., Peters J.A. A cytoplasmic region determines single-channel conductance in 5-HT3 receptors. Nature 2003, 424:321-324.
-
(2003)
Nature
, vol.424
, pp. 321-324
-
-
Kelley, S.P.1
Dunlop, J.I.2
Kirkness, E.F.3
Lambert, J.J.4
Peters, J.A.5
-
102
-
-
84876681700
-
An outline of desensitization in pentameric ligand-gated ion channel receptors
-
Keramidas A., Lynch J.W. An outline of desensitization in pentameric ligand-gated ion channel receptors. Cell. Mol. Life Sci. 2013, 70:1241-1253.
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 1241-1253
-
-
Keramidas, A.1
Lynch, J.W.2
-
103
-
-
3543062342
-
Ligand-gated ion channels: mechanisms underlying ion selectivity
-
Keramidas A., Moorhouse A.J., Schofield P.R., Barry P.H. Ligand-gated ion channels: mechanisms underlying ion selectivity. Prog. Biophys. Mol. Biol. 2004, 86:161-204.
-
(2004)
Prog. Biophys. Mol. Biol.
, vol.86
, pp. 161-204
-
-
Keramidas, A.1
Moorhouse, A.J.2
Schofield, P.R.3
Barry, P.H.4
-
104
-
-
84871927415
-
Structural basis of ligand recognition in 5-HT3 receptors
-
Kesters D., Thompson A.J., Brams M., van Elk R., Spurny R., Geitmann M., Villalgordo J.M., Guskov A., Danielson U.H., Lummis S.C.R., et al. Structural basis of ligand recognition in 5-HT3 receptors. EMBO Rep. 2013, 14:49-56.
-
(2013)
EMBO Rep.
, vol.14
, pp. 49-56
-
-
Kesters, D.1
Thompson, A.J.2
Brams, M.3
van Elk, R.4
Spurny, R.5
Geitmann, M.6
Villalgordo, J.M.7
Guskov, A.8
Danielson, U.H.9
Lummis, S.C.R.10
-
105
-
-
0042882982
-
Enzyme flexibility and enzyme action
-
Koshland D.E. Enzyme flexibility and enzyme action. J. Cell. Comp. Physiol. 1959, 54:245-258.
-
(1959)
J. Cell. Comp. Physiol.
, vol.54
, pp. 245-258
-
-
Koshland, D.E.1
-
106
-
-
41649109805
-
Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
-
Kracun S., Harkness P.C., Gibb A.J., Millar N.S. Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function. Br. J. Pharmacol. 2008, 153:1474-1484.
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 1474-1484
-
-
Kracun, S.1
Harkness, P.C.2
Gibb, A.J.3
Millar, N.S.4
-
107
-
-
79951621335
-
The long activations of α2 glycine channels can be described by a mechanism with reaction intermediates ("flip")
-
Krashia P., Lape R., Lodesani F., Colquhoun D., Sivilotti L.G. The long activations of α2 glycine channels can be described by a mechanism with reaction intermediates ("flip"). J. Gen. Physiol. 2011, 137:197-216.
-
(2011)
J. Gen. Physiol.
, vol.137
, pp. 197-216
-
-
Krashia, P.1
Lape, R.2
Lodesani, F.3
Colquhoun, D.4
Sivilotti, L.G.5
-
108
-
-
0025649599
-
Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor
-
Kuhse J., Schmieden V., Betz H. Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor. J. Biol. Chem. 1990, 265:22317-22320.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 22317-22320
-
-
Kuhse, J.1
Schmieden, V.2
Betz, H.3
-
109
-
-
0027400866
-
GABA rho 2 receptor pharmacological profile: GABA recognition site similarities to rho 1
-
Kusama T., Wang T.L., Guggino W.B., Cutting G.R., Uhl G.R. GABA rho 2 receptor pharmacological profile: GABA recognition site similarities to rho 1. Eur. J. Pharmacol. 1993, 245:83-84.
-
(1993)
Eur. J. Pharmacol.
, vol.245
, pp. 83-84
-
-
Kusama, T.1
Wang, T.L.2
Guggino, W.B.3
Cutting, G.R.4
Uhl, G.R.5
-
110
-
-
0029163027
-
Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
-
Labarca C., Nowak M.W., Zhang H., Tang L., Deshpande P., Lester H.A. Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature 1995, 376:514-516.
-
(1995)
Nature
, vol.376
, pp. 514-516
-
-
Labarca, C.1
Nowak, M.W.2
Zhang, H.3
Tang, L.4
Deshpande, P.5
Lester, H.A.6
-
111
-
-
28244486354
-
On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari
-
Langley J.N. On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari. J. Physiol. 1905, 33:374-413.
-
(1905)
J. Physiol.
, vol.33
, pp. 374-413
-
-
Langley, J.N.1
-
112
-
-
0001202076
-
Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer
-
Langosch D., Thomas L., Betz H. Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. Proc. Natl. Acad. Sci. USA 1988, 85:7394-7398.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7394-7398
-
-
Langosch, D.1
Thomas, L.2
Betz, H.3
-
113
-
-
49649102025
-
On the nature of partial agonism in the nicotinic receptor superfamily
-
Lape R., Colquhoun D., Sivilotti L.G. On the nature of partial agonism in the nicotinic receptor superfamily. Nature 2008, 454:722-727.
-
(2008)
Nature
, vol.454
, pp. 722-727
-
-
Lape, R.1
Colquhoun, D.2
Sivilotti, L.G.3
-
114
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., et al. Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23:2947-2948.
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
-
115
-
-
0034650875
-
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors
-
Laube B., Kuhse J., Betz H. Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors. J. Physiol. 2000, 522:215-230.
-
(2000)
J. Physiol.
, vol.522
, pp. 215-230
-
-
Laube, B.1
Kuhse, J.2
Betz, H.3
-
117
-
-
0036897309
-
Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia
-
Leonard S., Gault J., Hopkins J., Logel J., Vianzon R., Short M., Drebing C., Berger R., Venn D., Sirota P., et al. Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Arch. Gen. Psychiatry 2002, 59:1085-1096.
-
(2002)
Arch. Gen. Psychiatry
, vol.59
, pp. 1085-1096
-
-
Leonard, S.1
Gault, J.2
Hopkins, J.3
Logel, J.4
Vianzon, R.5
Short, M.6
Drebing, C.7
Berger, R.8
Venn, D.9
Sirota, P.10
-
118
-
-
26944473689
-
Sites of alcohol and volatile anesthetic action on glycine receptors
-
Lobo I.A., Harris R.A. Sites of alcohol and volatile anesthetic action on glycine receptors. Int. Rev. Neurobiol. 2005, 65:53-87.
-
(2005)
Int. Rev. Neurobiol.
, vol.65
, pp. 53-87
-
-
Lobo, I.A.1
Harris, R.A.2
-
119
-
-
84870031999
-
5-HT(3) receptors
-
Lummis S.C.R. 5-HT(3) receptors. J. Biol. Chem. 2012, 287:40239-40245.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 40239-40245
-
-
Lummis, S.C.R.1
-
120
-
-
77954512288
-
Mutations in GABAA receptor subunits associated with genetic epilepsies
-
Macdonald R.L., Kang J.-Q., Gallagher M.J. Mutations in GABAA receptor subunits associated with genetic epilepsies. J. Physiol. 2010, 588:1861-1869.
-
(2010)
J. Physiol.
, vol.588
, pp. 1861-1869
-
-
Macdonald, R.L.1
Kang, J.-Q.2
Gallagher, M.J.3
-
121
-
-
84920385268
-
Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study
-
Marabelli A., Lape R., Sivilotti L. Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study. J. Gen. Physiol. 2015, 145:23-45.
-
(2015)
J. Gen. Physiol.
, vol.145
, pp. 23-45
-
-
Marabelli, A.1
Lape, R.2
Sivilotti, L.3
-
122
-
-
0025997336
-
Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
-
Maricq A.V., Peterson A.S., Brake A.J., Myers R.M., Julius D. Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel. Science 1991, 254:432-437.
-
(1991)
Science
, vol.254
, pp. 432-437
-
-
Maricq, A.V.1
Peterson, A.S.2
Brake, A.J.3
Myers, R.M.4
Julius, D.5
-
123
-
-
0028814983
-
Cloning, sequence analysis and expression of two forms of mRNA coding for the human beta 2 subunit of the GABAA receptor
-
McKinley D.D., Lennon D.J., Carter D.B. Cloning, sequence analysis and expression of two forms of mRNA coding for the human beta 2 subunit of the GABAA receptor. Brain Res. Mol. Brain Res. 1995, 28:175-179.
-
(1995)
Brain Res. Mol. Brain Res.
, vol.28
, pp. 175-179
-
-
McKinley, D.D.1
Lennon, D.J.2
Carter, D.B.3
-
124
-
-
84905669878
-
Crystal structure of a human GABAA receptor
-
Miller P.S., Aricescu A.R. Crystal structure of a human GABAA receptor. Nature 2014, 512:270-275.
-
(2014)
Nature
, vol.512
, pp. 270-275
-
-
Miller, P.S.1
Aricescu, A.R.2
-
125
-
-
0036458391
-
Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system
-
Miquel M.C., Emerit M.B., Nosjean A., Simon A., Rumajogee P., Brisorgueil M.J., Doucet E., Hamon M., Vergé D. Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system. Eur. J. Neurosci. 2002, 15:449-457.
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 449-457
-
-
Miquel, M.C.1
Emerit, M.B.2
Nosjean, A.3
Simon, A.4
Rumajogee, P.5
Brisorgueil, M.J.6
Doucet, E.7
Hamon, M.8
Vergé, D.9
-
126
-
-
0022454719
-
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor
-
Mishina M., Takai T., Imoto K., Noda M., Takahashi T., Numa S., Methfessel C., Sakmann B. Molecular distinction between fetal and adult forms of muscle acetylcholine receptor. Nature 1986, 321:406-411.
-
(1986)
Nature
, vol.321
, pp. 406-411
-
-
Mishina, M.1
Takai, T.2
Imoto, K.3
Noda, M.4
Takahashi, T.5
Numa, S.6
Methfessel, C.7
Sakmann, B.8
-
127
-
-
79953805191
-
Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses
-
Miwa J.M., Freedman R., Lester H.A. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron 2011, 70:20-33.
-
(2011)
Neuron
, vol.70
, pp. 20-33
-
-
Miwa, J.M.1
Freedman, R.2
Lester, H.A.3
-
128
-
-
0032967642
-
Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall
-
Miyazawa A., Fujiyoshi Y., Stowell M., Unwin N. Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall. J. Mol. Biol. 1999, 288:765-786.
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 765-786
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Stowell, M.3
Unwin, N.4
-
129
-
-
84928663325
-
Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors
-
Mnatsakanyan N., Nishtala S.N., Pandhare A., Fiori M.C., Goyal R., Pauwels J.E., Navetta A.F., Ahrorov A., Jansen M. Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors. Biochemistry 2015, 54:2670-2682.
-
(2015)
Biochemistry
, vol.54
, pp. 2670-2682
-
-
Mnatsakanyan, N.1
Nishtala, S.N.2
Pandhare, A.3
Fiori, M.C.4
Goyal, R.5
Pauwels, J.E.6
Navetta, A.F.7
Ahrorov, A.8
Jansen, M.9
-
130
-
-
78651189765
-
On the Nature of Allosteric Transitions: A Plausible Model
-
Monod J., Wyman J., Changeux J.-P. On the Nature of Allosteric Transitions: A Plausible Model. J. Mol. Biol. 1965, 12:88-118.
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.-P.3
-
131
-
-
84930273363
-
Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure
-
Moraga-Cid G., Sauguet L., Huon C., Malherbe L., Girard-Blanc C., Petres S., Murail S., Taly A., Baaden M., Delarue M., Corringer P.J. Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure. Proc. Natl. Acad. Sci. USA 2015, 112:2865-2870.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 2865-2870
-
-
Moraga-Cid, G.1
Sauguet, L.2
Huon, C.3
Malherbe, L.4
Girard-Blanc, C.5
Petres, S.6
Murail, S.7
Taly, A.8
Baaden, M.9
Delarue, M.10
Corringer, P.J.11
-
132
-
-
84979859115
-
Atomistic insights into human Cys-loop receptors by solution NMR
-
Mowrey D.D., Kinde M.N., Xu Y., Tang P. Atomistic insights into human Cys-loop receptors by solution NMR. Biochim. Biophys. Acta 2015, 1848(1 Pt B):307-314.
-
(2015)
Biochim. Biophys. Acta
, vol.1848
, Issue.1
, pp. 307-314
-
-
Mowrey, D.D.1
Kinde, M.N.2
Xu, Y.3
Tang, P.4
-
133
-
-
67349279395
-
Detection and trapping of intermediate states priming nicotinic receptor channel opening
-
Mukhtasimova N., Lee W.Y., Wang H.L., Sine S.M. Detection and trapping of intermediate states priming nicotinic receptor channel opening. Nature 2009, 459:451-454.
-
(2009)
Nature
, vol.459
, pp. 451-454
-
-
Mukhtasimova, N.1
Lee, W.Y.2
Wang, H.L.3
Sine, S.M.4
-
134
-
-
82755162931
-
Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses
-
Nemecz A., Taylor P. Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses. J. Biol. Chem. 2011, 286:42555-42565.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 42555-42565
-
-
Nemecz, A.1
Taylor, P.2
-
135
-
-
0019175714
-
Permeability control by cholinergic receptors in Torpedo postsynaptic membranes: agonist dose-response relations measured at second and millisecond times
-
Neubig R.R., Cohen J.B. Permeability control by cholinergic receptors in Torpedo postsynaptic membranes: agonist dose-response relations measured at second and millisecond times. Biochemistry 1980, 19:2770-2779.
-
(1980)
Biochemistry
, vol.19
, pp. 2770-2779
-
-
Neubig, R.R.1
Cohen, J.B.2
-
136
-
-
73649096172
-
Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel
-
Nury H., Bocquet N., Le Poupon C., Raynal B., Haouz A., Corringer P.-J., Delarue M. Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel. J. Mol. Biol. 2010, 395:1114-1127.
-
(2010)
J. Mol. Biol.
, vol.395
, pp. 1114-1127
-
-
Nury, H.1
Bocquet, N.2
Le Poupon, C.3
Raynal, B.4
Haouz, A.5
Corringer, P.-J.6
Delarue, M.7
-
137
-
-
77950868175
-
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue
-
Nury H., Poitevin F., Van Renterghem C., Changeux J.-P., Corringer P.-J., Delarue M., Baaden M. One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc. Natl. Acad. Sci. USA 2010, 107:6275-6280.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 6275-6280
-
-
Nury, H.1
Poitevin, F.2
Van Renterghem, C.3
Changeux, J.-P.4
Corringer, P.-J.5
Delarue, M.6
Baaden, M.7
-
138
-
-
78751673139
-
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
-
Nury H., Van Renterghem C., Weng Y., Tran A., Baaden M., Dufresne V., Changeux J.-P., Sonner J.M., Delarue M., Corringer P.-J. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature 2011, 469:428-431.
-
(2011)
Nature
, vol.469
, pp. 428-431
-
-
Nury, H.1
Van Renterghem, C.2
Weng, Y.3
Tran, A.4
Baaden, M.5
Dufresne, V.6
Changeux, J.-P.7
Sonner, J.M.8
Delarue, M.9
Corringer, P.-J.10
-
139
-
-
84885651158
-
Structural insights into Cys-loop receptor function and ligand recognition
-
Nys M., Kesters D., Ulens C. Structural insights into Cys-loop receptor function and ligand recognition. Biochem. Pharmacol. 2013, 86:1042-1053.
-
(2013)
Biochem. Pharmacol.
, vol.86
, pp. 1042-1053
-
-
Nys, M.1
Kesters, D.2
Ulens, C.3
-
140
-
-
84859173541
-
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
-
Pan J., Chen Q., Willenbring D., Yoshida K., Tillman T., Kashlan O.B., Cohen A., Kong X.-P., Xu Y., Tang P. Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nat. Commun. 2012, 3:714.
-
(2012)
Nat. Commun.
, vol.3
, pp. 714
-
-
Pan, J.1
Chen, Q.2
Willenbring, D.3
Yoshida, K.4
Tillman, T.5
Kashlan, O.B.6
Cohen, A.7
Kong, X.-P.8
Xu, Y.9
Tang, P.10
-
141
-
-
79953141061
-
Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors
-
Papke D., Gonzalez-Gutierrez G., Grosman C. Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors. J. Physiol. 2011, 589:1571-1585.
-
(2011)
J. Physiol.
, vol.589
, pp. 1571-1585
-
-
Papke, D.1
Gonzalez-Gutierrez, G.2
Grosman, C.3
-
142
-
-
84941661770
-
Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism
-
Published online September 15, 2015
-
Pilorge M., Fassier C., Le Corronc H., Potey A., Bai J., De Gois S., Delaby E., Assouline B., Guinchat V., Devillard F., et al. Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Mol. Psychiatry 2015, Published online September 15, 2015. 10.1038/mp.2015.139.
-
(2015)
Mol. Psychiatry
-
-
Pilorge, M.1
Fassier, C.2
Le Corronc, H.3
Potey, A.4
Bai, J.5
De Gois, S.6
Delaby, E.7
Assouline, B.8
Guinchat, V.9
Devillard, F.10
-
143
-
-
67650169910
-
Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain
-
Pless S.A., Lynch J.W. Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain. J. Biol. Chem. 2009, 284:15847-15856.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15847-15856
-
-
Pless, S.A.1
Lynch, J.W.2
-
144
-
-
84861856196
-
A locally closed conformation of a bacterial pentameric proton-gated ion channel
-
Prevost M.S., Sauguet L., Nury H., Van Renterghem C., Huon C., Poitevin F., Baaden M., Delarue M., Corringer P.-J. A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat. Struct. Mol. Biol. 2012, 19:642-649.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 642-649
-
-
Prevost, M.S.1
Sauguet, L.2
Nury, H.3
Van Renterghem, C.4
Huon, C.5
Poitevin, F.6
Baaden, M.7
Delarue, M.8
Corringer, P.-J.9
-
145
-
-
84879036155
-
Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC
-
Prevost M.S., Delarue-Cochin S., Marteaux J., Colas C., Van Renterghem C., Blondel A., Malliavin T., Corringer P.-J., Joseph D. Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC. J. Med. Chem. 2013, 56:4619-4630.
-
(2013)
J. Med. Chem.
, vol.56
, pp. 4619-4630
-
-
Prevost, M.S.1
Delarue-Cochin, S.2
Marteaux, J.3
Colas, C.4
Van Renterghem, C.5
Blondel, A.6
Malliavin, T.7
Corringer, P.-J.8
Joseph, D.9
-
146
-
-
84885788447
-
Intermediate closed state for glycine receptor function revealed by cysteine cross-linking
-
Prevost M.S., Moraga-Cid G., Van Renterghem C., Edelstein S.J., Changeux J.-P., Corringer P.-J. Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proc. Natl. Acad. Sci. USA 2013, 110:17113-17118.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 17113-17118
-
-
Prevost, M.S.1
Moraga-Cid, G.2
Van Renterghem, C.3
Edelstein, S.J.4
Changeux, J.-P.5
Corringer, P.-J.6
-
147
-
-
0033538515
-
Acetylcholine and epibatidine binding to muscle acetylcholine receptors distinguish between concerted and uncoupled models
-
Prince R.J., Sine S.M. Acetylcholine and epibatidine binding to muscle acetylcholine receptors distinguish between concerted and uncoupled models. J. Biol. Chem. 1999, 274:19623-19629.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19623-19629
-
-
Prince, R.J.1
Sine, S.M.2
-
148
-
-
58549118250
-
Unliganded gating of acetylcholine receptor channels
-
Purohit P., Auerbach A. Unliganded gating of acetylcholine receptor channels. Proc. Natl. Acad. Sci. USA 2009, 106:115-120.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 115-120
-
-
Purohit, P.1
Auerbach, A.2
-
149
-
-
84890958919
-
Functional anatomy of an allosteric protein
-
Purohit P., Gupta S., Jadey S., Auerbach A. Functional anatomy of an allosteric protein. Nat. Commun. 2013, 4:2984.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2984
-
-
Purohit, P.1
Gupta, S.2
Jadey, S.3
Auerbach, A.4
-
150
-
-
0027509375
-
Novel GABA responses from rod-driven retinal horizontal cells
-
Qian H., Dowling J.E. Novel GABA responses from rod-driven retinal horizontal cells. Nature 1993, 361:162-164.
-
(1993)
Nature
, vol.361
, pp. 162-164
-
-
Qian, H.1
Dowling, J.E.2
-
151
-
-
0026079817
-
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
-
Revah F., Bertrand D., Galzi J.L., Devillers-Thiéry A., Mulle C., Hussy N., Bertrand S., Ballivet M., Changeux J.P. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature 1991, 353:846-849.
-
(1991)
Nature
, vol.353
, pp. 846-849
-
-
Revah, F.1
Bertrand, D.2
Galzi, J.L.3
Devillers-Thiéry, A.4
Mulle, C.5
Hussy, N.6
Bertrand, S.7
Ballivet, M.8
Changeux, J.P.9
-
152
-
-
84919924163
-
Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs
-
Rienzo M., Lummis S.C.R., Dougherty D.A. Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs. Chem. Biol. 2014, 21:1700-1706.
-
(2014)
Chem. Biol.
, vol.21
, pp. 1700-1706
-
-
Rienzo, M.1
Lummis, S.C.R.2
Dougherty, D.A.3
-
153
-
-
68349131630
-
Insight in nAChR subtype selectivity from AChBP crystal structures
-
Rucktooa P., Smit A.B., Sixma T.K. Insight in nAChR subtype selectivity from AChBP crystal structures. Biochem. Pharmacol. 2009, 78:777-787.
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 777-787
-
-
Rucktooa, P.1
Smit, A.B.2
Sixma, T.K.3
-
154
-
-
0028596378
-
Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channels
-
Rundström N., Schmieden V., Betz H., Bormann J., Langosch D. Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channels. Proc. Natl. Acad. Sci. USA 1994, 91:8950-8954.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8950-8954
-
-
Rundström, N.1
Schmieden, V.2
Betz, H.3
Bormann, J.4
Langosch, D.5
-
155
-
-
0019215162
-
Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist
-
Sakmann B., Patlak J., Neher E. Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature 1980, 286:71-73.
-
(1980)
Nature
, vol.286
, pp. 71-73
-
-
Sakmann, B.1
Patlak, J.2
Neher, E.3
-
156
-
-
84928550847
-
Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection
-
Sanders R.D., Grover V., Goulding J., Godlee A., Gurney S., Snelgrove R., Ma D., Singh S., Maze M., Hussell T. Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection. J. Neuroimmunol. 2015, 282:97-103.
-
(2015)
J. Neuroimmunol.
, vol.282
, pp. 97-103
-
-
Sanders, R.D.1
Grover, V.2
Goulding, J.3
Godlee, A.4
Gurney, S.5
Snelgrove, R.6
Ma, D.7
Singh, S.8
Maze, M.9
Hussell, T.10
-
157
-
-
84877732553
-
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel
-
Sauguet L., Howard R.J., Malherbe L., Lee U.S., Corringer P.-J., Harris R.A., Delarue M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat. Commun. 2013, 4:1697.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1697
-
-
Sauguet, L.1
Howard, R.J.2
Malherbe, L.3
Lee, U.S.4
Corringer, P.-J.5
Harris, R.A.6
Delarue, M.7
-
158
-
-
84875220675
-
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
-
Sauguet L., Poitevin F., Murail S., Van Renterghem C., Moraga-Cid G., Malherbe L., Thompson A.W., Koehl P., Corringer P.-J., Baaden M., Delarue M. Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. EMBO J. 2013, 32:728-741.
-
(2013)
EMBO J.
, vol.32
, pp. 728-741
-
-
Sauguet, L.1
Poitevin, F.2
Murail, S.3
Van Renterghem, C.4
Moraga-Cid, G.5
Malherbe, L.6
Thompson, A.W.7
Koehl, P.8
Corringer, P.-J.9
Baaden, M.10
Delarue, M.11
-
159
-
-
84892910277
-
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
-
Sauguet L., Shahsavar A., Poitevin F., Huon C., Menny A., Nemecz À., Haouz A., Changeux J.-P., Corringer P.-J., Delarue M. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc. Natl. Acad. Sci. USA 2014, 111:966-971.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 966-971
-
-
Sauguet, L.1
Shahsavar, A.2
Poitevin, F.3
Huon, C.4
Menny, A.5
Nemecz, À.6
Haouz, A.7
Changeux, J.-P.8
Corringer, P.-J.9
Delarue, M.10
-
160
-
-
84921029711
-
Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels
-
Sauguet L., Shahsavar A., Delarue M. Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels. Biochim. Biophys. Acta 2015, 1850:511-523.
-
(2015)
Biochim. Biophys. Acta
, vol.1850
, pp. 511-523
-
-
Sauguet, L.1
Shahsavar, A.2
Delarue, M.3
-
161
-
-
0033080914
-
Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating
-
Saul B., Kuner T., Sobetzko D., Brune W., Hanefeld F., Meinck H.M., Becker C.M. Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating. J. Neurosci. 1999, 19:869-877.
-
(1999)
J. Neurosci.
, vol.19
, pp. 869-877
-
-
Saul, B.1
Kuner, T.2
Sobetzko, D.3
Brune, W.4
Hanefeld, F.5
Meinck, H.M.6
Becker, C.M.7
-
162
-
-
84962826281
-
A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation
-
Schmandt N., Velisetty P., Chalamalasetti S.V., Stein R.A., Bonner R., Talley L., Parker M.D., Mchaourab H.S., Yee V.C., Lodowski D.T., Chakrapani S. A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation. J. Gen. Physiol. 2015, 146:323-340.
-
(2015)
J. Gen. Physiol.
, vol.146
, pp. 323-340
-
-
Schmandt, N.1
Velisetty, P.2
Chalamalasetti, S.V.3
Stein, R.A.4
Bonner, R.5
Talley, L.6
Parker, M.D.7
Mchaourab, H.S.8
Yee, V.C.9
Lodowski, D.T.10
Chakrapani, S.11
-
163
-
-
0024438902
-
Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor
-
Schmieden V., Grenningloh G., Schofield P.R., Betz H. Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor. EMBO J. 1989, 8:695-700.
-
(1989)
EMBO J.
, vol.8
, pp. 695-700
-
-
Schmieden, V.1
Grenningloh, G.2
Schofield, P.R.3
Betz, H.4
-
164
-
-
0027518923
-
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium
-
Séguéla P., Wadiche J., Dineley-Miller K., Dani J.A., Patrick J.W. Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. J. Neurosci. 1993, 13:596-604.
-
(1993)
J. Neurosci.
, vol.13
, pp. 596-604
-
-
Séguéla, P.1
Wadiche, J.2
Dineley-Miller, K.3
Dani, J.A.4
Patrick, J.W.5
-
165
-
-
0038493551
-
Asymmetric contribution of alpha and beta subunits to the activation of alphabeta heteromeric glycine receptors
-
Shan Q., Nevin S.T., Haddrill J.L., Lynch J.W. Asymmetric contribution of alpha and beta subunits to the activation of alphabeta heteromeric glycine receptors. J. Neurochem. 2003, 86:498-507.
-
(2003)
J. Neurochem.
, vol.86
, pp. 498-507
-
-
Shan, Q.1
Nevin, S.T.2
Haddrill, J.L.3
Lynch, J.W.4
-
166
-
-
0030449918
-
Functional expression of GABA rho 3 receptors in Xenopus oocytes
-
Shingai R., Yanagi K., Fukushima T., Sakata K., Ogurusu T. Functional expression of GABA rho 3 receptors in Xenopus oocytes. Neurosci. Res. 1996, 26:387-390.
-
(1996)
Neurosci. Res.
, vol.26
, pp. 387-390
-
-
Shingai, R.1
Yanagi, K.2
Fukushima, T.3
Sakata, K.4
Ogurusu, T.5
-
167
-
-
84864060207
-
End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease
-
Sine S.M. End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease. Physiol. Rev. 2012, 92:1189-1234.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 1189-1234
-
-
Sine, S.M.1
-
168
-
-
73549120879
-
What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor
-
Sivilotti L.G. What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor. J. Physiol. 2010, 588:45-58.
-
(2010)
J. Physiol.
, vol.588
, pp. 45-58
-
-
Sivilotti, L.G.1
-
170
-
-
0028354969
-
Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc
-
Smart T.G., Xie X., Krishek B.J. Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc. Prog. Neurobiol. 1994, 42:393-441.
-
(1994)
Prog. Neurobiol.
, vol.42
, pp. 393-441
-
-
Smart, T.G.1
Xie, X.2
Krishek, B.J.3
-
171
-
-
68149176875
-
Role of acetylcholine receptor domains in ion selectivity
-
Song C., Corry B. Role of acetylcholine receptor domains in ion selectivity. Biochim. Biophys. Acta 2009, 1788:1466-1473.
-
(2009)
Biochim. Biophys. Acta
, vol.1788
, pp. 1466-1473
-
-
Song, C.1
Corry, B.2
-
172
-
-
84868116573
-
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines
-
Spurny R., Ramerstorfer J., Price K., Brams M., Ernst M., Nury H., Verheij M., Legrand P., Bertrand D., Bertrand S., et al. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proc. Natl. Acad. Sci. USA 2012, 109:E3028-E3034.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E3028-E3034
-
-
Spurny, R.1
Ramerstorfer, J.2
Price, K.3
Brams, M.4
Ernst, M.5
Nury, H.6
Verheij, M.7
Legrand, P.8
Bertrand, D.9
Bertrand, S.10
-
173
-
-
84875476238
-
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC)
-
Spurny R., Billen B., Howard R.J., Brams M., Debaveye S., Price K.L., Weston D.A., Strelkov S.V., Tytgat J., Bertrand S., et al. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). J. Biol. Chem. 2013, 288:8355-8364.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 8355-8364
-
-
Spurny, R.1
Billen, B.2
Howard, R.J.3
Brams, M.4
Debaveye, S.5
Price, K.L.6
Weston, D.A.7
Strelkov, S.V.8
Tytgat, J.9
Bertrand, S.10
-
174
-
-
84929179462
-
Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor
-
Spurny R., Debaveye S., Farinha A., Veys K., Vos A.M., Gossas T., Atack J., Bertrand S., Bertrand D., Danielson U.H., et al. Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA 2015, 112:E2543-E2552.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E2543-E2552
-
-
Spurny, R.1
Debaveye, S.2
Farinha, A.3
Veys, K.4
Vos, A.M.5
Gossas, T.6
Atack, J.7
Bertrand, S.8
Bertrand, D.9
Danielson, U.H.10
-
175
-
-
84870921351
-
Ion channel mutations in neuronal diseases: a genetics perspective
-
Steinlein O.K. Ion channel mutations in neuronal diseases: a genetics perspective. Chem. Rev. 2012, 112:6334-6352.
-
(2012)
Chem. Rev.
, vol.112
, pp. 6334-6352
-
-
Steinlein, O.K.1
-
176
-
-
22244438519
-
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism
-
Taly A., Delarue M., Grutter T., Nilges M., Le Novère N., Corringer P.-J., Changeux J.-P. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys. J. 2005, 88:3954-3965.
-
(2005)
Biophys. J.
, vol.88
, pp. 3954-3965
-
-
Taly, A.1
Delarue, M.2
Grutter, T.3
Nilges, M.4
Le Novère, N.5
Corringer, P.-J.6
Changeux, J.-P.7
-
177
-
-
26944443142
-
Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels
-
Tasneem A., Iyer L.M., Jakobsson E., Aravind L. Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels. Genome Biol. 2005, 6:R4.
-
(2005)
Genome Biol.
, vol.6
, pp. R4
-
-
Tasneem, A.1
Iyer, L.M.2
Jakobsson, E.3
Aravind, L.4
-
178
-
-
34548672882
-
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
-
Taylor P., Talley T.T., Radic' Z., Hansen S.B., Hibbs R.E., Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochem. Pharmacol. 2007, 74:1164-1171.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 1164-1171
-
-
Taylor, P.1
Talley, T.T.2
Radic', Z.3
Hansen, S.B.4
Hibbs, R.E.5
Shi, J.6
-
180
-
-
84901044877
-
ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation
-
Tillman T.S., Seyoum E., Mowrey D.D., Xu Y., Tang P. ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation. J. Biol. Chem. 2014, 289:13851-13857.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 13851-13857
-
-
Tillman, T.S.1
Seyoum, E.2
Mowrey, D.D.3
Xu, Y.4
Tang, P.5
-
181
-
-
79851500104
-
Assembly of nicotinic and other Cys-loop receptors
-
Tsetlin V., Kuzmin D., Kasheverov I. Assembly of nicotinic and other Cys-loop receptors. J. Neurochem. 2011, 116:734-741.
-
(2011)
J. Neurochem.
, vol.116
, pp. 734-741
-
-
Tsetlin, V.1
Kuzmin, D.2
Kasheverov, I.3
-
182
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J. Mol. Biol. 2005, 346:967-989.
-
(2005)
J. Mol. Biol.
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
183
-
-
84868258417
-
Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC)
-
Velisetty P., Chalamalasetti S.V., Chakrapani S. Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC). J. Biol. Chem. 2012, 287:36864-36872.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36864-36872
-
-
Velisetty, P.1
Chalamalasetti, S.V.2
Chakrapani, S.3
-
184
-
-
84948680382
-
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders
-
Vien T.N., Modgil A., Abramian A.M., Jurd R., Walker J., Brandon N.J., Terunuma M., Rudolph U., Maguire J., Davies P.A., Moss S.J. Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders. Proc. Natl. Acad. Sci. USA 2015, 112:14805-14810.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 14805-14810
-
-
Vien, T.N.1
Modgil, A.2
Abramian, A.M.3
Jurd, R.4
Walker, J.5
Brandon, N.J.6
Terunuma, M.7
Rudolph, U.8
Maguire, J.9
Davies, P.A.10
Moss, S.J.11
-
185
-
-
80055074583
-
Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor
-
Wang Q., Lynch J.W. Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor. J. Biol. Chem. 2011, 286:38814-38824.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 38814-38824
-
-
Wang, Q.1
Lynch, J.W.2
-
186
-
-
40149111452
-
Control of cation permeation through the nicotinic receptor channel
-
Wang H.L., Cheng X., Taylor P., McCammon J.A., Sine S.M. Control of cation permeation through the nicotinic receptor channel. PLoS Comput. Biol. 2008, 4:e41.
-
(2008)
PLoS Comput. Biol.
, vol.4
, pp. e41
-
-
Wang, H.L.1
Cheng, X.2
Taylor, P.3
McCammon, J.A.4
Sine, S.M.5
-
187
-
-
67650354191
-
Single-channel current through nicotinic receptor produced by closure of binding site C-loop
-
Wang H.L., Toghraee R., Papke D., Cheng X.L., McCammon J.A., Ravaioli U., Sine S.M. Single-channel current through nicotinic receptor produced by closure of binding site C-loop. Biophys. J. 2009, 96:3582-3590.
-
(2009)
Biophys. J.
, vol.96
, pp. 3582-3590
-
-
Wang, H.L.1
Toghraee, R.2
Papke, D.3
Cheng, X.L.4
McCammon, J.A.5
Ravaioli, U.6
Sine, S.M.7
-
188
-
-
84863116433
-
Intramembrane proton binding site linked to activation of bacterial pentameric ion channel
-
Wang H.L., Cheng X., Sine S.M. Intramembrane proton binding site linked to activation of bacterial pentameric ion channel. J. Biol. Chem. 2012, 287:6482-6489.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 6482-6489
-
-
Wang, H.L.1
Cheng, X.2
Sine, S.M.3
-
189
-
-
74049110470
-
Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel
-
Weng Y., Yang L., Corringer P.-J., Sonner J.M. Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel. Anesth. Analg. 2009, 110:59-63.
-
(2009)
Anesth. Analg.
, vol.110
, pp. 59-63
-
-
Weng, Y.1
Yang, L.2
Corringer, P.-J.3
Sonner, J.M.4
-
190
-
-
49449094458
-
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
-
Wessler I., Kirkpatrick C.J. Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br. J. Pharmacol. 2008, 154:1558-1571.
-
(2008)
Br. J. Pharmacol.
, vol.154
, pp. 1558-1571
-
-
Wessler, I.1
Kirkpatrick, C.J.2
-
191
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
Wilson G.G., Karlin A. The location of the gate in the acetylcholine receptor channel. Neuron 1998, 20:1269-1281.
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
-
192
-
-
0031574240
-
Identification of a Zn2+ binding site on the murine GABAA receptor complex: dependence on the second transmembrane domain of beta subunits
-
Wooltorton J.R., McDonald B.J., Moss S.J., Smart T.G. Identification of a Zn2+ binding site on the murine GABAA receptor complex: dependence on the second transmembrane domain of beta subunits. J. Physiol. 1997, 505:633-640.
-
(1997)
J. Physiol.
, vol.505
, pp. 633-640
-
-
Wooltorton, J.R.1
McDonald, B.J.2
Moss, S.J.3
Smart, T.G.4
-
193
-
-
63649149427
-
Nicotine binding to brain receptors requires a strong cation-pi interaction
-
Xiu X., Puskar N.L., Shanata J.A.P., Lester H.A., Dougherty D.A. Nicotine binding to brain receptors requires a strong cation-pi interaction. Nature 2009, 458:534-537.
-
(2009)
Nature
, vol.458
, pp. 534-537
-
-
Xiu, X.1
Puskar, N.L.2
Shanata, J.A.P.3
Lester, H.A.4
Dougherty, D.A.5
-
194
-
-
84877839928
-
Cholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease
-
Yakel J.L. Cholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease. Pflugers Arch. 2013, 465:441-450.
-
(2013)
Pflugers Arch.
, vol.465
, pp. 441-450
-
-
Yakel, J.L.1
-
195
-
-
0027194134
-
Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes
-
Yakel J.L., Lagrutta A., Adelman J.P., North R.A. Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 1993, 90:5030-5033.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5030-5033
-
-
Yakel, J.L.1
Lagrutta, A.2
Adelman, J.P.3
North, R.A.4
-
196
-
-
73449109898
-
Conformational changes in the nicotinic acetylcholine receptor during gating and desensitization
-
Yamodo I.H., Chiara D.C., Cohen J.B., Miller K.W. Conformational changes in the nicotinic acetylcholine receptor during gating and desensitization. Biochemistry 2010, 49:156-165.
-
(2010)
Biochemistry
, vol.49
, pp. 156-165
-
-
Yamodo, I.H.1
Chiara, D.C.2
Cohen, J.B.3
Miller, K.W.4
-
197
-
-
0042209595
-
Modulation of glycine-activated ion channel function by G-protein betagamma subunits
-
Yevenes G.E., Peoples R.W., Tapia J.C., Parodi J., Soto X., Olate J., Aguayo L.G. Modulation of glycine-activated ion channel function by G-protein betagamma subunits. Nat. Neurosci. 2003, 6:819-824.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 819-824
-
-
Yevenes, G.E.1
Peoples, R.W.2
Tapia, J.C.3
Parodi, J.4
Soto, X.5
Olate, J.6
Aguayo, L.G.7
-
198
-
-
84886589178
-
A propofol binding site on mammalian GABAA receptors identified by photolabeling
-
Yip G.M.S., Chen Z.-W., Edge C.J., Smith E.H., Dickinson R., Hohenester E., Townsend R.R., Fuchs K., Sieghart W., Evers A.S., Franks N.P. A propofol binding site on mammalian GABAA receptors identified by photolabeling. Nat. Chem. Biol. 2013, 9:715-720.
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 715-720
-
-
Yip, G.M.S.1
Chen, Z.-W.2
Edge, C.J.3
Smith, E.H.4
Dickinson, R.5
Hohenester, E.6
Townsend, R.R.7
Fuchs, K.8
Sieghart, W.9
Evers, A.S.10
Franks, N.P.11
-
199
-
-
70349453711
-
Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders
-
Zhao C., Xu Z., Wang F., Chen J., Ng S.-K., Wong P.-W., Yu Z., Pun F.W., Ren L., Lo W.-S., et al. Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders. PLoS ONE 2009, 4:e6977.
-
(2009)
PLoS ONE
, vol.4
, pp. e6977
-
-
Zhao, C.1
Xu, Z.2
Wang, F.3
Chen, J.4
Ng, S.-K.5
Wong, P.-W.6
Yu, Z.7
Pun, F.W.8
Ren, L.9
Lo, W.-S.10
-
200
-
-
79959775185
-
Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC
-
Zimmermann I., Dutzler R. Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC. PLoS Biol. 2011, 9:e1001101.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1001101
-
-
Zimmermann, I.1
Dutzler, R.2
-
201
-
-
84909942884
-
Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain
-
Zouridakis M., Giastas P., Zarkadas E., Chroni-Tzartou D., Bregestovski P., Tzartos S.J. Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain. Nat. Struct. Mol. Biol. 2014, 21:976-980.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 976-980
-
-
Zouridakis, M.1
Giastas, P.2
Zarkadas, E.3
Chroni-Tzartou, D.4
Bregestovski, P.5
Tzartos, S.J.6
-
202
-
-
84879528475
-
Structure and superorganization of acetylcholine receptor-rapsyn complexes
-
Zuber B., Unwin N. Structure and superorganization of acetylcholine receptor-rapsyn complexes. Proc. Natl. Acad. Sci. USA 2013, 110:10622-10627.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10622-10627
-
-
Zuber, B.1
Unwin, N.2
|