-
1
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
Karlin, A. Emerging structure of the nicotinic acetylcholine receptors. Nature Rev. Neurosci. 3, 102-114 (2002).
-
(2002)
Nature Rev. Neurosci
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
2
-
-
2542432136
-
Cys-loop receptors: New twists and turns
-
Lester, H. A., Dibas, M. I., Dahan, D. S., Leite, J. F. & Dougherty, D. A. Cys-loop receptors: new twists and turns. Trends Neurosci. 27, 329-336 (2004).
-
(2004)
Trends Neurosci
, vol.27
, pp. 329-336
-
-
Lester, H.A.1
Dibas, M.I.2
Dahan, D.S.3
Leite, J.F.4
Dougherty, D.A.5
-
3
-
-
33645302360
-
Recent advances in Cys-loop receptor structure and function
-
Sine, S. M. & Engel, A. G. Recent advances in Cys-loop receptor structure and function. Nature 440, 448-455 (2006).
-
(2006)
Nature
, vol.440
, pp. 448-455
-
-
Sine, S.M.1
Engel, A.G.2
-
4
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc, K. et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 411, 269-276 (2001).
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
-
5
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
Celie, P. H. et al. Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron 41, 907-914 (2004).
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.1
-
6
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen, S. B. et al. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J. 24, 3635-3646 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
-
7
-
-
0242488935
-
Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy
-
Unwin, N. Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy. FEBS Lett. 555, 91-95 (2003).
-
(2003)
FEBS Lett
, vol.555
, pp. 91-95
-
-
Unwin, N.1
-
8
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa, A., Fujiyoshi, Y. & Unwin, N. Structure and gating mechanism of the acetylcholine receptor pore. Nature 423, 949-955 (2003).
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
9
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
-
Unwin, N. Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution. J. Mol. Biol. 346, 967-989 (2005).
-
(2005)
J. Mol. Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
10
-
-
26944443142
-
Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels
-
Tasneem, A., Iyer, L. M., Jakobsson, E. & Aravind, L. Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels. Genome Biol. 6, R4 (2005).
-
(2005)
Genome Biol
, vol.6
-
-
Tasneem, A.1
Iyer, L.M.2
Jakobsson, E.3
Aravind, L.4
-
11
-
-
33846106078
-
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
-
Bocquet, N. et al. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature 445, 116-119 (2007).
-
(2007)
Nature
, vol.445
, pp. 116-119
-
-
Bocquet, N.1
-
12
-
-
0018894860
-
The permeability of endplate channels to monovalent and divalent metal cations
-
Adams, D. J., Dwyer, T. M. & Hille, B. The permeability of endplate channels to monovalent and divalent metal cations. J. Gen. Physiol. 75, 493-510 (1980).
-
(1980)
J. Gen. Physiol
, vol.75
, pp. 493-510
-
-
Adams, D.J.1
Dwyer, T.M.2
Hille, B.3
-
14
-
-
34247375206
-
A stepwise mechanism for acetylcholine receptor channel gating
-
Purohit, P., Mitra, A. & Auerbach, A. A stepwise mechanism for acetylcholine receptor channel gating. Nature 446, 930-933 (2007).
-
(2007)
Nature
, vol.446
, pp. 930-933
-
-
Purohit, P.1
Mitra, A.2
Auerbach, A.3
-
15
-
-
0029954238
-
A single residue in theM2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors
-
Campos-Caro, A. et al. A single residue in theM2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors. Proc. Natl Acad. Sci. USA 93, 6118-6123 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 6118-6123
-
-
Campos-Caro, A.1
-
16
-
-
0033811476
-
The extracellular linker of muscle acetylcholine receptor channels is a gating control element
-
Grosman, C., Salamone, F. N., Sine, S. M. & Auerbach, A. The extracellular linker of muscle acetylcholine receptor channels is a gating control element. J. Gen. Physiol. 116, 327-340 (2000).
-
(2000)
J. Gen. Physiol
, vol.116
, pp. 327-340
-
-
Grosman, C.1
Salamone, F.N.2
Sine, S.M.3
Auerbach, A.4
-
19
-
-
0037418859
-
Gating the selectivity filter in ClC chloride channels
-
Dutzler, R., Campbell, E. B. & MacKinnon, R. Gating the selectivity filter in ClC chloride channels. Science 300, 108-112 (2003).
-
(2003)
Science
, vol.300
, pp. 108-112
-
-
Dutzler, R.1
Campbell, E.B.2
MacKinnon, R.3
-
20
-
-
0035970016
-
Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine- accessibility method
-
Wilson, G. & Karlin, A. Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine- accessibility method. Proc. Natl Acad. Sci. USA 98, 1241-1248 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 1241-1248
-
-
Wilson, G.1
Karlin, A.2
-
21
-
-
27644473642
-
Pore conformations and gating mechanism of a Cys-loop receptor
-
Paas, Y. et al. Pore conformations and gating mechanism of a Cys-loop receptor. Proc. Natl Acad. Sci. USA 102, 15877-15882 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15877-15882
-
-
Paas, Y.1
-
22
-
-
0035172258
-
LGICdb: The ligand-gated ion channel database
-
Le Novere, N. & Changeux, J. P. LGICdb: the ligand-gated ion channel database. Nucleic Acids Res. 29, 294-295 (2001).
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 294-295
-
-
Le Novere, N.1
Changeux, J.P.2
-
23
-
-
0025802063
-
Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel
-
Konno,T. et al. Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel. Proc R. Soc. Lond. B 244, 69-79 (1991).
-
(1991)
Proc R. Soc. Lond. B
, vol.244
, pp. 69-79
-
-
Konno, T.1
-
24
-
-
0026705789
-
Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations
-
Cohen, B. N., Labarca, C., Davidson, N. & Lester, H. A. Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations. J. Gen. Physiol. 100, 373-400 (1992).
-
(1992)
J. Gen. Physiol
, vol.100
, pp. 373-400
-
-
Cohen, B.N.1
Labarca, C.2
Davidson, N.3
Lester, H.A.4
-
25
-
-
0033119869
-
Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor
-
Corringer, P. J. et al. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron 22, 831-843 (1999).
-
(1999)
Neuron
, vol.22
, pp. 831-843
-
-
Corringer, P.J.1
-
26
-
-
0035815730
-
Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily
-
Gunthorpe, M. J. & Lummis, S. C. Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily. J. Biol. Chem. 276, 10977-10983 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 10977-10983
-
-
Gunthorpe, M.J.1
Lummis, S.C.2
-
27
-
-
0023748825
-
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
-
Imoto, K. et al. Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Nature 335, 645-648 (1988).
-
(1988)
Nature
, vol.335
, pp. 645-648
-
-
Imoto, K.1
-
28
-
-
0026079817
-
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
-
Revah, F. et al. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature 353, 846-849 (1991).
-
(1991)
Nature
, vol.353
, pp. 846-849
-
-
Revah, F.1
-
29
-
-
33745907550
-
A hydrophobic gate in an ion channel: The closed state of the nicotinic acetylcholine receptor
-
Beckstein, O. & Sansom, M. S. A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor. Phys. Biol. 3, 147-159 (2006).
-
(2006)
Phys. Biol
, vol.3
, pp. 147-159
-
-
Beckstein, O.1
Sansom, M.S.2
-
30
-
-
30744470883
-
Probing ion-channel pores one proton at a time
-
Cymes, G. D., Ni, Y. & Grosman, C. Probing ion-channel pores one proton at a time. Nature 438, 975-980 (2005).
-
(2005)
Nature
, vol.438
, pp. 975-980
-
-
Cymes, G.D.1
Ni, Y.2
Grosman, C.3
-
31
-
-
0027879008
-
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
-
Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Cryst. 26, 795-800 (1993).
-
(1993)
J. Appl. Cryst
, vol.26
, pp. 795-800
-
-
Kabsch, W.1
-
32
-
-
0028103275
-
Number 4. The CCP4 suite: Programs for X-ray crystallography
-
Collaborative Computational Project
-
Collaborative Computational Project, Number 4. The CCP4 suite: programs for X-ray crystallography. Acta Crystallogr. D 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 760-763
-
-
-
33
-
-
4644366388
-
HKL2MAP: A graphical user interface for phasing with SHELX programs
-
Pape, T. & Schneider, T. R. HKL2MAP: a graphical user interface for phasing with SHELX programs. J. Appl. Cryst. 37, 843-844 (2004).
-
(2004)
J. Appl. Cryst
, vol.37
, pp. 843-844
-
-
Pape, T.1
Schneider, T.R.2
-
35
-
-
0031059866
-
-
eds Carter, C. W. & Sweet, R. M, Academic, New York
-
de La Fortelle, E. & Bricogne, G. in Methods in Enzymology (eds Carter, C. W. & Sweet, R. M.) 492-494 (Academic, New York, 1997).
-
(1997)
Methods in Enzymology
, pp. 492-494
-
-
de La Fortelle, E.1
Bricogne, G.2
-
36
-
-
0002583957
-
An automated procedure for phase improvement by density modification. Joint CCP4 ESF-EACBM Newslett
-
Cowtan, K. An automated procedure for phase improvement by density modification. Joint CCP4 ESF-EACBM Newslett. Protein Crystallogr. 31, 34-38 (1994).
-
(1994)
Protein Crystallogr
, vol.31
, pp. 34-38
-
-
Cowtan, K.1
-
37
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47, 110-119 (1991).
-
(1991)
Acta Crystallogr. A
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
38
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A. T. et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D 54, 905-921 (1998).
-
(1998)
Acta Crystallogr. D
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
-
39
-
-
0030404988
-
HOLE: A program for the analysis of the pore dimensions of ion channel structural models. 14, 354-360
-
Smart, O. S., Neduvelil, J. G., Wang, X., Wallace, B. A. & Sansom, M. S. HOLE: a program for the analysis of the pore dimensions of ion channel structural models. 14, 354-360 J. Mol. Graph. 14, 354-360, 376 (1996).
-
(1996)
J. Mol. Graph
, vol.14
, Issue.354-360
, pp. 376
-
-
Smart, O.S.1
Neduvelil, J.G.2
Wang, X.3
Wallace, B.A.4
Sansom, M.S.5
-
40
-
-
0030040323
-
Reduced surface: An efficient way to compute molecular surfaces
-
Sanner, M. F., Olson, A. J. & Spehner, J. C. Reduced surface: an efficient way to compute molecular surfaces. Biopolymers 38, 305-320 (1996).
-
(1996)
Biopolymers
, vol.38
, pp. 305-320
-
-
Sanner, M.F.1
Olson, A.J.2
Spehner, J.C.3
-
42
-
-
84986512474
-
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
-
Brooks, B. R. et al. CHARMM: a program for macromolecular energy, minimization, and dynamics calculations. J. Comput. Chem. 4, 187-217 (1983).
-
(1983)
J. Comput. Chem
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
-
43
-
-
0032096837
-
Continuum salvation model: Electrostatic forces from numerical solutions to the Poisson-Bolztmann equation
-
Im, W., Beglov, D. & Roux, B. Continuum salvation model: electrostatic forces from numerical solutions to the Poisson-Bolztmann equation. Comput. Phys. Commun. 111, 59-75 (1998).
-
(1998)
Comput. Phys. Commun
, vol.111
, pp. 59-75
-
-
Im, W.1
Beglov, D.2
Roux, B.3
|