A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels

Comptes Rendus - Biologies

Volumn 328, Issue 3, 2005, Pages 223-234

  Grutter, Thomas ^a   de Carvalho, Lia Prado ^a   Dufresne, Virginie ^a   Taly, Antoine ^a   Fischer, Markus ^b   Changeux, Jean Pierre ^a  

^a INSTITUT PASTEUR   (France)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE BINDING PROTEIN; ALPHA BUNGAROTOXIN; ANION; BINDING PROTEIN; CATION; EPIBATIDINE; GLYCINE; HYBRID PROTEIN; ION CHANNEL; LIGAND; MEMBRANE RECEPTOR; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

BIOLOGY; ION; SIGNALING;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING COMPETITION; BINDING SITE; CELL LABELING; CELL MEMBRANE; CELL STRAIN HEK293; CELL SURFACE; CHANNEL GATING; CHIMERA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; ELECTRIC CURRENT; GENE EXPRESSION; GENE FUSION; GENE TARGETING; GENETIC CODE; GENETIC STABILITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIGAND BINDING; PATCH CLAMP; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEDIMENTATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SUCROSE GRADIENT; WHOLE CELL;

ACETYLCHOLINE; ALLOSTERIC REGULATION; CARRIER PROTEINS; CELLS, CULTURED; ION CHANNELS; RECEPTORS, SEROTONIN, 5-HT3; RECOMBINANT FUSION PROTEINS;

STAPHYLOCOCCUS PHAGE 3A;

EID: 14844323974     PISSN: 16310691     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.crvi.2004.11.004     Document Type: Article

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