Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors

Neuropharmacology

Volumn 96, Issue PB, 2015, Pages 169-177

  Forman, Stuart A ^a,b   Chiara, David C ^b   Miller, Keith W ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Alcohol; Allosterism; Barbiturates; Mutagenesis; Photolabel; Propofol

Indexed keywords

ANESTHETIC AGENT; LIGAND GATED ION CHANNEL; NICOTINIC RECEPTOR; NICOTINIC AGENT;

ARTICLE; BINDING AFFINITY; CHANNEL GATING; CRYSTALLOGRAPHY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG TARGETING; MOLECULAR RECOGNITION; OLIGOMERIZATION; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; ALLOSTERISM; ANIMAL; BINDING SITE; BRAIN; CHEMISTRY; HUMAN; METABOLISM; NERVE CELL; PROTEIN SECONDARY STRUCTURE; SKELETAL MUSCLE;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANESTHETICS, GENERAL; ANIMALS; BRAIN; HUMANS; MUSCLE, SKELETAL; NEURONS; NICOTINIC AGONISTS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, NICOTINIC;

EID: 84932193678     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.10.002     Document Type: Review

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