-
1
-
-
0028174238
-
Ethanol modulation of the gamma-aminobutyric acidA- and glycine-activated Cl- current in cultured mouse neurons
-
Aguayo LG, Pancetti FC (1994) Ethanol modulation of the gamma-aminobutyric acidA- and glycine-activated Cl- current in cultured mouse neurons. J Pharmacol Exp Ther 270(1):61-69.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, Issue.1
, pp. 61-69
-
-
Aguayo, L.G.1
Pancetti, F.C.2
-
2
-
-
59349093291
-
Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesia
-
Akopian AN, Ruparel NB, Jeske NA, Patwardhan A, Hargreaves KM (2009) Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesia. Trends Pharmacol Sci 30(2):79-84.
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.2
, pp. 79-84
-
-
Akopian, A.N.1
Ruparel, N.B.2
Jeske, N.A.3
Patwardhan, A.4
Hargreaves, K.M.5
-
3
-
-
0024495884
-
Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site
-
Alifimoff JK, Firestone LL, Miller KW (1989) Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site. Br J Pharmacol 96(1):9-16.
-
(1989)
Br J Pharmacol
, vol.96
, Issue.1
, pp. 9-16
-
-
Alifimoff, J.K.1
Firestone, L.L.2
Miller, K.W.3
-
4
-
-
48249106771
-
Mechanism of low level hyperbaric ethanol antagonism: specificity versus other drugs
-
Alkana RL, Jones BL, Palomares ML, Crabbe JC, Bejanian M (1992) Mechanism of low level hyperbaric ethanol antagonism: specificity versus other drugs. Alcohol Alcohol Suppl 1:63.
-
(1992)
Alcohol Alcohol Suppl
, vol.1
, pp. 63
-
-
Alkana, R.L.1
Jones, B.L.2
Palomares, M.L.3
Crabbe, J.C.4
Bejanian, M.5
-
5
-
-
0019364171
-
Low-level hyperbaric ethanol antagonism in mice. Dose and pressure response
-
Alkana RL, Malcolm RD (1981) Low-level hyperbaric ethanol antagonism in mice. Dose and pressure response. Pharmacology 22(3):199-208.
-
(1981)
Pharmacology
, vol.22
, Issue.3
, pp. 199-208
-
-
Alkana, R.L.1
Malcolm, R.D.2
-
6
-
-
36749008588
-
Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism
-
Arora K, Brooks CL (2007) Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism. Proc Natl Acad Sci USA 104(47):18496-18501.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.47
, pp. 18496-18501
-
-
Arora, K.1
Brooks, C.L.2
-
7
-
-
68149164775
-
A discrete alcohol pocket involved in GIRK channel activation
-
Aryal P, Dvir H, Choe S, Slesinger PA (2009) A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci 12(8):988-995.
-
(2009)
Nat Neurosci
, vol.12
, Issue.8
, pp. 988-995
-
-
Aryal, P.1
Dvir, H.2
Choe, S.3
Slesinger, P.A.4
-
8
-
-
77956257859
-
Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors
-
Asatryan L, Popova M, Perkins D, Trudell JR, Alkana RL, Davies DL (2010) Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors. J Pharmacol Exp Ther 334(3):720-728.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, Issue.3
, pp. 720-728
-
-
Asatryan, L.1
Popova, M.2
Perkins, D.3
Trudell, J.R.4
Alkana, R.L.5
Davies, D.L.6
-
9
-
-
34948851846
-
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs
-
Bandell M, Macpherson LJ, Patapoutian A (2007) From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs. Curr Opin Neurobiol 17(4):490-497.
-
(2007)
Curr Opin Neurobiol
, vol.17
, Issue.4
, pp. 490-497
-
-
Bandell, M.1
Macpherson, L.J.2
Patapoutian, A.3
-
10
-
-
0032958688
-
Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells
-
Basavarajappa BS, Hungund BL (1999) Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. J Neurochem 72(2):522-528.
-
(1999)
J Neurochem
, vol.72
, Issue.2
, pp. 522-528
-
-
Basavarajappa, B.S.1
Hungund, B.L.2
-
11
-
-
0036019414
-
Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview
-
Basavarajappa BS, Hungund BL (2002) Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview. Prostaglandins Leukot Essent Fatty Acids 66(2-3):287-299.
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.66
, Issue.2-3
, pp. 287-299
-
-
Basavarajappa, B.S.1
Hungund, B.L.2
-
12
-
-
70350786962
-
Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity
-
Baur R, Kaur KH, Sigel E (2009) Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity. J Neurochem 111(5):1172-1181.
-
(2009)
J Neurochem
, vol.111
, Issue.5
, pp. 1172-1181
-
-
Baur, R.1
Kaur, K.H.2
Sigel, E.3
-
13
-
-
0036733135
-
Anesthetic and ethanol effects on spontaneously opening glycine receptor channels
-
Beckstead MJ, Phelan R, Trudell JR, Bianchini MJ, Mihic SJ (2002) Anesthetic and ethanol effects on spontaneously opening glycine receptor channels. J Neurochem 82(6):1343-1351.
-
(2002)
J Neurochem
, vol.82
, Issue.6
, pp. 1343-1351
-
-
Beckstead, M.J.1
Phelan, R.2
Trudell, J.R.3
Bianchini, M.J.4
Mihic, S.J.5
-
14
-
-
0027133480
-
Low-level hyperbaric antagonism of ethanol-induced locomotor depression in C57BL/6J mice: dose response
-
Bejanian M, Jones BL, Alkana RL (1993) Low-level hyperbaric antagonism of ethanol-induced locomotor depression in C57BL/6J mice: dose response. Alcohol Clin Exp Res 17(5):935-939.
-
(1993)
Alcohol Clin Exp Res
, vol.17
, Issue.5
, pp. 935-939
-
-
Bejanian, M.1
Jones, B.L.2
Alkana, R.L.3
-
15
-
-
0001674354
-
General anaesthetic action at transmitter-gated inhibitory amino acid receptors
-
Belelli D, Pistis M, Peters JA, Lambert JJ (1999) General anaesthetic action at transmitter-gated inhibitory amino acid receptors. Trends Pharmacol Sci 20(12):496-502.
-
(1999)
Trends Pharmacol Sci
, vol.20
, Issue.12
, pp. 496-502
-
-
Belelli, D.1
Pistis, M.2
Peters, J.A.3
Lambert, J.J.4
-
16
-
-
33846169081
-
Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate
-
Benedikt J, Teisinger J, Vyklicky L, Vlachova V (2007) Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4, 5-bisphosphate. J Neurochem 100(1):211-224.
-
(2007)
J Neurochem
, vol.100
, Issue.1
, pp. 211-224
-
-
Benedikt, J.1
Teisinger, J.2
Vyklicky, L.3
Vlachova, V.4
-
17
-
-
44449105649
-
Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein
-
Bertaccini EJ, Lindahl E, Sixma T, Trudell JR (2008) Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein. J Chem Inf Model 48(4):855-860.
-
(2008)
J Chem Inf Model
, vol.48
, Issue.4
, pp. 855-860
-
-
Bertaccini, E.J.1
Lindahl, E.2
Sixma, T.3
Trudell, J.R.4
-
18
-
-
34547653836
-
Normal-mode analysis of the glycine alpha1 receptor by three separate methods
-
Bertaccini EJ, Trudell JR, Lindahl E (2007) Normal-mode analysis of the glycine alpha1 receptor by three separate methods. J Chem Inf Model 47(4):1572-1579.
-
(2007)
J Chem Inf Model
, vol.47
, Issue.4
, pp. 1572-1579
-
-
Bertaccini, E.J.1
Trudell, J.R.2
Lindahl, E.3
-
19
-
-
77955897919
-
Normal mode gating motions of a ligand-gated ion channel persist in a fully hydrated lipid bilayer model
-
Bertaccini EJ, Trudell JR, Lindahl E (2010a) Normal mode gating motions of a ligand-gated ion channel persist in a fully hydrated lipid bilayer model. ACS Chem Neurosci 1(8):552-558.
-
(2010)
ACS Chem Neurosci
, vol.1
, Issue.8
, pp. 552-558
-
-
Bertaccini, E.J.1
Trudell, J.R.2
Lindahl, E.3
-
20
-
-
78650696902
-
Modeling anesthetic binding sites within the glycine alpha one receptor based on prokaryotic ion channel templates: the problem with TM4
-
Bertaccini EJ, Wallner B, Trudell JR, Lindahl E (2010b) Modeling anesthetic binding sites within the glycine alpha one receptor based on prokaryotic ion channel templates: the problem with TM4. J Chem Inf Model 50(12):2248-2255.
-
(2010)
J Chem Inf Model
, vol.50
, Issue.12
, pp. 2248-2255
-
-
Bertaccini, E.J.1
Wallner, B.2
Trudell, J.R.3
Lindahl, E.4
-
21
-
-
41149095488
-
How membrane proteins sense voltage
-
Bezanilla F (2008) How membrane proteins sense voltage. Nat Rev Mol Cell Biol 9(4):323-332.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.4
, pp. 323-332
-
-
Bezanilla, F.1
-
22
-
-
0142059776
-
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
-
Bhave G, Hu H-J, Glauner KS, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci USA 100(21):12480-12485.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.21
, pp. 12480-12485
-
-
Bhave, G.1
Hu, H.-J.2
Glauner, K.S.3
Zhu, W.4
Wang, H.5
Brasier, D.J.6
Oxford, G.S.7
Gereau, R.W.8
-
23
-
-
0034751335
-
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
-
Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V (2001) Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol 134(4):845-852.
-
(2001)
Br J Pharmacol
, vol.134
, Issue.4
, pp. 845-852
-
-
Bisogno, T.1
Hanus, L.2
De Petrocellis, L.3
Tchilibon, S.4
Ponde, D.E.5
Brandi, I.6
Moriello, A.S.7
Davis, J.B.8
Mechoulam, R.9
Di Marzo, V.10
-
24
-
-
60149083725
-
Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol
-
Blednov YA, Harris RA (2009) Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol. Neuropharmacology 56(4):814-820.
-
(2009)
Neuropharmacology
, vol.56
, Issue.4
, pp. 814-820
-
-
Blednov, Y.A.1
Harris, R.A.2
-
25
-
-
0037422541
-
A pervasive mechanism for analgesia: activation of GIRK2 channels
-
Blednov YA, Stoffel M, Alva H, Harris RA (2003) A pervasive mechanism for analgesia: activation of GIRK2 channels. Proc Natl Acad Sci USA 100(1):277-282.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 277-282
-
-
Blednov, Y.A.1
Stoffel, M.2
Alva, H.3
Harris, R.A.4
-
26
-
-
0034920540
-
Potassium channels as targets for ethanol: studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice
-
Blednov YA, Stoffel M, Chang SR, Harris RA (2001) Potassium channels as targets for ethanol: studies of G-protein-coupled inwardly rectifying potassium channel 2 (GIRK2) null mutant mice. J Pharmacol Exp Ther 298(2):521-530.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, Issue.2
, pp. 521-530
-
-
Blednov, Y.A.1
Stoffel, M.2
Chang, S.R.3
Harris, R.A.4
-
27
-
-
34250788750
-
Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results
-
Borghese CM, Harris RA (2007) Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol 41(3):155-162.
-
(2007)
Alcohol
, vol.41
, Issue.3
, pp. 155-162
-
-
Borghese, C.M.1
Harris, R.A.2
-
28
-
-
0141630638
-
Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors
-
Borghese CM, Henderson LA, Bleck V, Trudell JR, Harris RA (2003) Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. J Pharmacol Exp Ther 307(1):42-52.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, Issue.1
, pp. 42-52
-
-
Borghese, C.M.1
Henderson, L.A.2
Bleck, V.3
Trudell, J.R.4
Harris, R.A.5
-
29
-
-
33644762013
-
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol
-
Borghese CM, Stórustovu Sí, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA (2006) The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther 316(3):1360-1368.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, Issue.3
, pp. 1360-1368
-
-
Borghese, C.M.1
Stórustovu, S.2
Ebert, B.3
Herd, M.B.4
Belelli, D.5
Lambert, J.J.6
Marshall, G.7
Wafford, K.A.8
Harris, R.A.9
-
30
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, Sixma TK (2001) Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 411(6835):269-276.
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 269-276
-
-
Brejc, K.1
van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
31
-
-
0030777012
-
The capsaicin receptor: a heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389(6653):816-824.
-
(1997)
Nature
, vol.389
, Issue.6653
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
32
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
Celie PHN, van Rossum-Fikkert SE, van Dijk WJ, Brejc K, Smit AB, Sixma TK (2004) Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron 41(6):907-914.
-
(2004)
Neuron
, vol.41
, Issue.6
, pp. 907-914
-
-
Celie, P.H.N.1
van Rossum-Fikkert, S.E.2
van Dijk, W.J.3
Brejc, K.4
Smit, A.B.5
Sixma, T.K.6
-
33
-
-
11844258265
-
A speed limit for conformational change of an allosteric membrane protein
-
Chakrapani S, Auerbach A (2005) A speed limit for conformational change of an allosteric membrane protein. Proc Natl Acad Sci USA 102(1):87-92.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.1
, pp. 87-92
-
-
Chakrapani, S.1
Auerbach, A.2
-
34
-
-
41149149832
-
Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: implications for the channel potentiation mechanism
-
Cheng MH, Coalson RD, Cascio M (2008) Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: implications for the channel potentiation mechanism. Proteins 71(2):972-981.
-
(2008)
Proteins
, vol.71
, Issue.2
, pp. 972-981
-
-
Cheng, M.H.1
Coalson, R.D.2
Cascio, M.3
-
35
-
-
0037111866
-
Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice
-
Choi D-S, Wang D, Dadgar J, Chang WS, Messing RO (2002) Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. J Neurosci 22(22):9905-9911.
-
(2002)
J Neurosci
, vol.22
, Issue.22
, pp. 9905-9911
-
-
Choi, D.-S.1
Wang, D.2
Dadgar, J.3
Chang, W.S.4
Messing, R.O.5
-
36
-
-
54349124083
-
General anesthetics sensitize the capsaicin receptor transient receptor potential V1
-
Cornett PM, Matta JA, Ahern GP (2008) General anesthetics sensitize the capsaicin receptor transient receptor potential V1. Mol Pharmacol 74:1261-1268.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1261-1268
-
-
Cornett, P.M.1
Matta, J.A.2
Ahern, G.P.3
-
37
-
-
34548238595
-
Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors
-
Crawford DK, Trudell JR, Bertaccini EJ, Li K, Davies DL, Alkana RL (2007) Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors. J Neurochem 102(6):2097-2109.
-
(2007)
J Neurochem
, vol.102
, Issue.6
, pp. 2097-2109
-
-
Crawford, D.K.1
Trudell, J.R.2
Bertaccini, E.J.3
Li, K.4
Davies, D.L.5
Alkana, R.L.6
-
38
-
-
4444368781
-
Identification of a general anesthetic binding site in the diacylglycerol-binding domain of protein kinase Cδ
-
Das J, Addona GH, Sandberg WS, Husain SS, Stehle T, Miller KW (2004) Identification of a general anesthetic binding site in the diacylglycerol-binding domain of protein kinase Cδ. J Biol Chem 279(36):37964-37972.
-
(2004)
J Biol Chem
, vol.279
, Issue.36
, pp. 37964-37972
-
-
Das, J.1
Addona, G.H.2
Sandberg, W.S.3
Husain, S.S.4
Stehle, T.5
Miller, K.W.6
-
39
-
-
69249224549
-
PKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domain
-
Das J, Pany S, Rahman GM, Slater SJ (2009) PKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domain. Biochem J 421(3):405-413.
-
(2009)
Biochem J
, vol.421
, Issue.3
, pp. 405-413
-
-
Das, J.1
Pany, S.2
Rahman, G.M.3
Slater, S.J.4
-
40
-
-
67349104492
-
Crystal structure of an alcohol complexed with the second cysteine-rich domain of protein kinase C delta
-
202A [abstract].
-
Das J, Shunmugasundararaj S, Stehle T, Miller KW (2007) Crystal structure of an alcohol complexed with the second cysteine-rich domain of protein kinase C delta. Alcohol Clin Exp Res 31(6 Suppl):202A [abstract].
-
(2007)
Alcohol Clin Exp Res
, vol.31
, Issue.6 SUPPL.
-
-
Das, J.1
Shunmugasundararaj, S.2
Stehle, T.3
Miller, K.W.4
-
41
-
-
0031790198
-
Direct antagonism of ethanol's effects on GABA(A) receptors by increased atmospheric pressure
-
Davies DL, Alkana RL (1998) Direct antagonism of ethanol's effects on GABA(A) receptors by increased atmospheric pressure. Alcohol Clin Exp Res 22(8):1689-1697.
-
(1998)
Alcohol Clin Exp Res
, vol.22
, Issue.8
, pp. 1689-1697
-
-
Davies, D.L.1
Alkana, R.L.2
-
42
-
-
0034745425
-
Ethanol enhances GABAA receptor function in short sleep and long sleep mouse brain membranes
-
Davies DL, Alkana RL (2001) Ethanol enhances GABAA receptor function in short sleep and long sleep mouse brain membranes. Alcohol Clin Exp Res 25(3):478-483.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, Issue.3
, pp. 478-483
-
-
Davies, D.L.1
Alkana, R.L.2
-
43
-
-
0032947573
-
In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol
-
Davies DL, Bolger MB, Brinton RD, Finn DA, Alkana RL (1999) In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol. Psychopharmacology (Berl) 141(4):339-350.
-
(1999)
Psychopharmacology (Berl)
, vol.141
, Issue.4
, pp. 339-350
-
-
Davies, D.L.1
Bolger, M.B.2
Brinton, R.D.3
Finn, D.A.4
Alkana, R.L.5
-
44
-
-
2642524354
-
Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism
-
Davies DL, Crawford DK, Trudell JR, Mihic SJ, Alkana RL (2004) Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism. J Neurochem 89(5):1175-1185.
-
(2004)
J Neurochem
, vol.89
, Issue.5
, pp. 1175-1185
-
-
Davies, D.L.1
Crawford, D.K.2
Trudell, J.R.3
Mihic, S.J.4
Alkana, R.L.5
-
45
-
-
0027972945
-
Low-level hyperbaric antagonism of ethanol's anticonvulsant property in C57BL/6J mice
-
446 [abstract].
-
Davies DL, Morland J, Jones BL, Palomares ML, Alkana RL (1994) Low-level hyperbaric antagonism of ethanol's anticonvulsant property in C57BL/6J mice. Alcohol Clin Exp Res 18(2):446 [abstract].
-
(1994)
Alcohol Clin Exp Res
, vol.18
, Issue.2
-
-
Davies, D.L.1
Morland, J.2
Jones, B.L.3
Palomares, M.L.4
Alkana, R.L.5
-
46
-
-
0038662943
-
Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure
-
Davies DL, Trudell JR, Mihic SJ, Crawford DK, Alkana RL (2003) Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure. Alcohol Clin Exp Res 27(5):743-755.
-
(2003)
Alcohol Clin Exp Res
, vol.27
, Issue.5
, pp. 743-755
-
-
Davies, D.L.1
Trudell, J.R.2
Mihic, S.J.3
Crawford, D.K.4
Alkana, R.L.5
-
47
-
-
0024947536
-
Mechanism of action of ethanol: initial central nervous system actions
-
Deitrich RA, Dunwiddie TV, Harris RA, Erwin VG (1989) Mechanism of action of ethanol: initial central nervous system actions. Pharmacol Rev 41(4):489-537.
-
(1989)
Pharmacol Rev
, vol.41
, Issue.4
, pp. 489-537
-
-
Deitrich, R.A.1
Dunwiddie, T.V.2
Harris, R.A.3
Erwin, V.G.4
-
48
-
-
44249117614
-
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
-
De Petrocellis L, Vellani V, Schiano-Moriello A, Marini P, Magherini PC, Orlando P, Di Marzo V (2008) Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. J Pharmacol Exp Ther 325(3):1007-1015.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, Issue.3
, pp. 1007-1015
-
-
De Petrocellis, L.1
Vellani, V.2
Schiano-Moriello, A.3
Marini, P.4
Magherini, P.C.5
Orlando, P.6
Di Marzo, V.7
-
49
-
-
0031459734
-
Molecular interactions between inhaled anesthetics and proteins
-
Eckenhoff RG, Johansson JS (1997) Molecular interactions between inhaled anesthetics and proteins. Pharmacol Rev 49(4):343-367.
-
(1997)
Pharmacol Rev
, vol.49
, Issue.4
, pp. 343-367
-
-
Eckenhoff, R.G.1
Johansson, J.S.2
-
50
-
-
0033748287
-
Developmental changes in the modulation of synaptic glycine receptors by ethanol
-
Eggers ED, O'Brien JA, Berger AJ (2000) Developmental changes in the modulation of synaptic glycine receptors by ethanol. J Neurophysiol 84(5):2409-2416.
-
(2000)
J Neurophysiol
, vol.84
, Issue.5
, pp. 2409-2416
-
-
Eggers, E.D.1
O'Brien, J.A.2
Berger, A.J.3
-
51
-
-
57849168293
-
Reduced oral ethanol avoidance in mice lacking transient receptor potential channel vanilloid receptor 1
-
Ellingson JM, Silbaugh BC, Brasser SM (2008) Reduced oral ethanol avoidance in mice lacking transient receptor potential channel vanilloid receptor 1. Behav Genet 39(1):62-72.
-
(2008)
Behav Genet
, vol.39
, Issue.1
, pp. 62-72
-
-
Ellingson, J.M.1
Silbaugh, B.C.2
Brasser, S.M.3
-
52
-
-
0025900316
-
Effect of ethanol on gamma-aminobutyric acid and glycine receptor-coupled Cl- fluxes in rat brain synaptoneurosomes
-
Engblom AC, Akerman KE (1991) Effect of ethanol on gamma-aminobutyric acid and glycine receptor-coupled Cl- fluxes in rat brain synaptoneurosomes. J Neurochem 57(2):384-390.
-
(1991)
J Neurochem
, vol.57
, Issue.2
, pp. 384-390
-
-
Engblom, A.C.1
Akerman, K.E.2
-
53
-
-
0031003845
-
Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected
-
Flood P, Ramirez-Latorre J, Role L (1997) Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected. Anesthesiology 86(4):859-865.
-
(1997)
Anesthesiology
, vol.86
, Issue.4
, pp. 859-865
-
-
Flood, P.1
Ramirez-Latorre, J.2
Role, L.3
-
54
-
-
2942597685
-
Identification of a tetramerization domain in the C terminus of the vanilloid receptor
-
García-Sanz N, Fernández-Carvajal A, Morenilla-Palao C, Planells-Cases R, Fajardo-Sánchez E, Fernández-Ballester G, Ferrer-Montiel A (2004) Identification of a tetramerization domain in the C terminus of the vanilloid receptor. J Neurosci 24(23):5307-5314.
-
(2004)
J Neurosci
, vol.24
, Issue.23
, pp. 5307-5314
-
-
García-Sanz, N.1
Fernández-Carvajal, A.2
Morenilla-Palao, C.3
Planells-Cases, R.4
Fajardo-Sánchez, E.5
Fernández-Ballester, G.6
Ferrer-Montiel, A.7
-
55
-
-
23044479980
-
Anandamide transport: a critical review
-
Glaser ST, Kaczocha M, Deutsch DG (2005) Anandamide transport: a critical review. Life Sci 77(14):1584-1604.
-
(2005)
Life Sci
, vol.77
, Issue.14
, pp. 1584-1604
-
-
Glaser, S.T.1
Kaczocha, M.2
Deutsch, D.G.3
-
56
-
-
0030861703
-
Ethanol alters the subcellular localization of delta- and epsilon protein kinase C in NG108-15 cells
-
Gordon AS, Yao L, Wu ZL, Coe IR, Diamond I (1997) Ethanol alters the subcellular localization of delta- and epsilon protein kinase C in NG108-15 cells. Mol Pharmacol 52(4):554-559.
-
(1997)
Mol Pharmacol
, vol.52
, Issue.4
, pp. 554-559
-
-
Gordon, A.S.1
Yao, L.2
Wu, Z.L.3
Coe, I.R.4
Diamond, I.5
-
57
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman C, Zhou M, Auerbach A (2000) Mapping the conformational wave of acetylcholine receptor channel gating. Nature 403(6771):773-776.
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 773-776
-
-
Grosman, C.1
Zhou, M.2
Auerbach, A.3
-
58
-
-
51449101925
-
Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin
-
Grycova L, Lansky Z, Friedlova E, Obsilova V, Janouskova H, Obsil T, Teisinger J (2008) Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin. Biochem Biophys Res Commun 375(4):680-683.
-
(2008)
Biochem Biophys Res Commun
, vol.375
, Issue.4
, pp. 680-683
-
-
Grycova, L.1
Lansky, Z.2
Friedlova, E.3
Obsilova, V.4
Janouskova, H.5
Obsil, T.6
Teisinger, J.7
-
59
-
-
33744813823
-
Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptors
-
Hanchar HJ, Chutsrinopkun P, Meera P, Supavilai P, Sieghart W, Wallner M, Olsen RW (2006) Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptors. Proc Natl Acad Sci USA 103(22):8546-8551.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.22
, pp. 8546-8551
-
-
Hanchar, H.J.1
Chutsrinopkun, P.2
Meera, P.3
Supavilai, P.4
Sieghart, W.5
Wallner, M.6
Olsen, R.W.7
-
60
-
-
14544274549
-
Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity
-
Hanchar HJ, Dodson PD, Olsen RW, Otis TS, Wallner M (2005) Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity. Nat Neurosci 8(3):339-345.
-
(2005)
Nat Neurosci
, vol.8
, Issue.3
, pp. 339-345
-
-
Hanchar, H.J.1
Dodson, P.D.2
Olsen, R.W.3
Otis, T.S.4
Wallner, M.5
-
62
-
-
0024161813
-
Alcohol and marijuana: comparative dose effect profiles in humans
-
Heishman SJ, Stitzer ML, Bigelow GE (1988) Alcohol and marijuana: comparative dose effect profiles in humans. Pharmacol Biochem Behav 31(3):649-655.
-
(1988)
Pharmacol Biochem Behav
, vol.31
, Issue.3
, pp. 649-655
-
-
Heishman, S.J.1
Stitzer, M.L.2
Bigelow, G.E.3
-
63
-
-
46249092554
-
Gromacs 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation
-
Hess B, Kutzner C, van der Spoel D, Lindahl E (2008) Gromacs 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation. J Chem Theory Comput 4:435-447.
-
(2008)
J Chem Theory Comput
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
van der Spoel, D.3
Lindahl, E.4
-
64
-
-
0033325668
-
Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon
-
Hodge CW, Mehmert KK, Kelley SP, McMahon T, Haywood A, Olive MF, Wang D, Sanchez-Perez AM, Messing RO (1999) Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon. Nat Neurosci 2(11):997-1002.
-
(1999)
Nat Neurosci
, vol.2
, Issue.11
, pp. 997-1002
-
-
Hodge, C.W.1
Mehmert, K.K.2
Kelley, S.P.3
McMahon, T.4
Haywood, A.5
Olive, M.F.6
Wang, D.7
Sanchez-Perez, A.M.8
Messing, R.O.9
-
65
-
-
0034018628
-
Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence
-
Hungund BL, Basavarajappa BS (2000) Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. Alcohol Alcohol 35(2):126-133.
-
(2000)
Alcohol Alcohol
, vol.35
, Issue.2
, pp. 126-133
-
-
Hungund, B.L.1
Basavarajappa, B.S.2
-
66
-
-
34547130933
-
Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels
-
Inanobe A, Matsuura T, Nakagawa A, Kurachi Y (2007) Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels. Channels (Austin) 1(1):39-45.
-
(2007)
Channels (Austin)
, vol.1
, Issue.1
, pp. 39-45
-
-
Inanobe, A.1
Matsuura, T.2
Nakagawa, A.3
Kurachi, Y.4
-
67
-
-
0036753545
-
The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment
-
Jin T, Peng L, Mirshahi T, Rohacs T, Chan KW, Sanchez R, Logothetis DE (2002) The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment. Mol Cell 10(3):469-481.
-
(2002)
Mol Cell
, vol.10
, Issue.3
, pp. 469-481
-
-
Jin, T.1
Peng, L.2
Mirshahi, T.3
Rohacs, T.4
Chan, K.W.5
Sanchez, R.6
Logothetis, D.E.7
-
68
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt S-E, Bautista DM, Chuang H-H, McKemy DD, Zygmunt PM, Högestätt ED, Meng ID, Julius D (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427(6971):260-265.
-
(2004)
Nature
, vol.427
, Issue.6971
, pp. 260-265
-
-
Jordt, S.-E.1
Bautista, D.M.2
Chuang, H.-H.3
McKemy, D.D.4
Zygmunt, P.M.5
Högestätt, E.D.6
Meng, I.D.7
Julius, D.8
-
69
-
-
0036183319
-
Molecular basis for species-specific sensitivity to "hot" chili peppers
-
Jordt S-E, Julius D (2002) Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108(3):421-430.
-
(2002)
Cell
, vol.108
, Issue.3
, pp. 421-430
-
-
Jordt, S.-E.1
Julius, D.2
-
70
-
-
0032321487
-
Substituted-cysteine accessibility method
-
Karlin A, Akabas MH (1998) Substituted-cysteine accessibility method. Meth Enzymol 293:123-145.
-
(1998)
Meth Enzymol
, vol.293
, pp. 123-145
-
-
Karlin, A.1
Akabas, M.H.2
-
71
-
-
63349100394
-
Hot flash: TRPV channels in the brain
-
Kauer JA, Gibson HE (2009) Hot flash: TRPV channels in the brain. Trends Neurosci 32(4):215-224.
-
(2009)
Trends Neurosci
, vol.32
, Issue.4
, pp. 215-224
-
-
Kauer, J.A.1
Gibson, H.E.2
-
72
-
-
0033490103
-
Ethanol opens G-protein-activated inwardly rectifying K+ channels
-
Kobayashi T, Ikeda K, Kojima H, Niki H, Yano R, Yoshioka T, Kumanishi T (1999) Ethanol opens G-protein-activated inwardly rectifying K+ channels. Nat Neurosci 2(12):1091-1097.
-
(1999)
Nat Neurosci
, vol.2
, Issue.12
, pp. 1091-1097
-
-
Kobayashi, T.1
Ikeda, K.2
Kojima, H.3
Niki, H.4
Yano, R.5
Yoshioka, T.6
Kumanishi, T.7
-
73
-
-
60649098946
-
Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies
-
Korepanova A, Pereda-Lopez A, Solomon LR, Walter KA, Lake MR, Bianchi BR, McDonald HA, Neelands TR, Shen J, Matayoshi ED, Moreland RB, Chiu ML (2009) Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies. Protein Expr Purif 65(1):38-50.
-
(2009)
Protein Expr Purif
, vol.65
, Issue.1
, pp. 38-50
-
-
Korepanova, A.1
Pereda-Lopez, A.2
Solomon, L.R.3
Walter, K.A.4
Lake, M.R.5
Bianchi, B.R.6
McDonald, H.A.7
Neelands, T.R.8
Shen, J.9
Matayoshi, E.D.10
Moreland, R.B.11
Chiu, M.L.12
-
74
-
-
70349126720
-
Mapping a barbiturate withdrawal locus to a 0.44Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol
-
Kozell LB, Walter NAR, Milner LC, Wickman K, Buck KJ (2009) Mapping a barbiturate withdrawal locus to a 0.44Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol. J Neurosci 29(37):11662-11673.
-
(2009)
J Neurosci
, vol.29
, Issue.37
, pp. 11662-11673
-
-
Kozell, L.B.1
Walter, N.A.R.2
Milner, L.C.3
Wickman, K.4
Buck, K.J.5
-
75
-
-
0033567181
-
General anaesthetic actions on ligand-gated ion channels
-
Krasowski MD, Harrison NL (1999) General anaesthetic actions on ligand-gated ion channels. Cell Mol Life Sci 55(10):1278-1303.
-
(1999)
Cell Mol Life Sci
, vol.55
, Issue.10
, pp. 1278-1303
-
-
Krasowski, M.D.1
Harrison, N.L.2
-
76
-
-
0041819527
-
Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster
-
Kruse SW, Zhao R, Smith DP, Jones DNM (2003) Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster. Nat Struct Biol 10(9):694-700.
-
(2003)
Nat Struct Biol
, vol.10
, Issue.9
, pp. 694-700
-
-
Kruse, S.W.1
Zhao, R.2
Smith, D.P.3
Jones, D.N.M.4
-
77
-
-
64549140109
-
Burning cold: involvement of TRPA1 in noxious cold sensation
-
Kwan KY, Corey DP (2009) Burning cold: involvement of TRPA1 in noxious cold sensation. J Gen Physiol 133(3):251-256.
-
(2009)
J Gen Physiol
, vol.133
, Issue.3
, pp. 251-256
-
-
Kwan, K.Y.1
Corey, D.P.2
-
78
-
-
67349137286
-
Amygdala protein kinase C epsilon controls alcohol consumption
-
Lesscher HMB, Wallace MJ, Zeng L, Wang V, Deitchman JK, McMahon T, Messing RO, Newton PM (2009) Amygdala protein kinase C epsilon controls alcohol consumption. Genes Brain Behav 8(5):493-499.
-
(2009)
Genes Brain Behav
, vol.8
, Issue.5
, pp. 493-499
-
-
Lesscher, H.M.B.1
Wallace, M.J.2
Zeng, L.3
Wang, V.4
Deitchman, J.K.5
McMahon, T.6
Messing, R.O.7
Newton, P.M.8
-
79
-
-
0033490206
-
G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action
-
Lewohl JM, Wilson WR, Mayfield RD, Brozowski SJ, Morrisett RA, Harris RA (1999) G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. Nat Neurosci 2(12):1084-1090.
-
(1999)
Nat Neurosci
, vol.2
, Issue.12
, pp. 1084-1090
-
-
Lewohl, J.M.1
Wilson, W.R.2
Mayfield, R.D.3
Brozowski, S.J.4
Morrisett, R.A.5
Harris, R.A.6
-
80
-
-
33747858757
-
NOMAD-Ref: visualization, deformation and refinement of macromolecular structures based on all-atom normal mode analysis
-
Web Server Issue
-
Lindahl E, Azuara C, Koehl P, Delarue M (2006) NOMAD-Ref: visualization, deformation and refinement of macromolecular structures based on all-atom normal mode analysis. Nucleic Acids Res 34(Web Server Issue):W52-W56.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Lindahl, E.1
Azuara, C.2
Koehl, P.3
Delarue, M.4
-
81
-
-
34250190946
-
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
-
Lishko PV, Procko E, Jin X, Phelps CB, Gaudet R (2007) The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron 54(6):905-918.
-
(2007)
Neuron
, vol.54
, Issue.6
, pp. 905-918
-
-
Lishko, P.V.1
Procko, E.2
Jin, X.3
Phelps, C.B.4
Gaudet, R.5
-
82
-
-
75649084889
-
Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations
-
Liu LT, Haddadian EJ, Willenbring D, Xu Y, Tang P (2010) Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations. J Phys Chem B 114(1):626-632.
-
(2010)
J Phys Chem B
, vol.114
, Issue.1
, pp. 626-632
-
-
Liu, L.T.1
Haddadian, E.J.2
Willenbring, D.3
Xu, Y.4
Tang, P.5
-
83
-
-
70349154294
-
General anesthetic binding to neuronal alpha4beta2 nicotinic acetylcholine receptor and its effects on global dynamics
-
Liu LT, Willenbring D, Xu Y, Tang P (2009) General anesthetic binding to neuronal alpha4beta2 nicotinic acetylcholine receptor and its effects on global dynamics. J Phys Chem B 113(37):12581-12589.
-
(2009)
J Phys Chem B
, vol.113
, Issue.37
, pp. 12581-12589
-
-
Liu, L.T.1
Willenbring, D.2
Xu, Y.3
Tang, P.4
-
84
-
-
26944473689
-
Sites of alcohol and volatile anesthetic action on glycine receptors
-
Lobo IA, Harris RA (2005) Sites of alcohol and volatile anesthetic action on glycine receptors. Int Rev Neurobiol 65:53-87.
-
(2005)
Int Rev Neurobiol
, vol.65
, pp. 53-87
-
-
Lobo, I.A.1
Harris, R.A.2
-
85
-
-
39849110727
-
Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation
-
Lobo IA, Harris RA, Trudell JR (2008) Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation. J Neurochem 104(6):1649-1662.
-
(2008)
J Neurochem
, vol.104
, Issue.6
, pp. 1649-1662
-
-
Lobo, I.A.1
Harris, R.A.2
Trudell, J.R.3
-
86
-
-
4043094149
-
Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics
-
Lobo IA, Mascia MP, Trudell JR, Harris RA (2004a) Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. J Biol Chem 279(32):33919-33927.
-
(2004)
J Biol Chem
, vol.279
, Issue.32
, pp. 33919-33927
-
-
Lobo, I.A.1
Mascia, M.P.2
Trudell, J.R.3
Harris, R.A.4
-
87
-
-
4143058002
-
Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening
-
Lobo IA, Trudell JR, Harris RA (2004b) Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. J Neurochem 90(4):962-969.
-
(2004)
J Neurochem
, vol.90
, Issue.4
, pp. 962-969
-
-
Lobo, I.A.1
Trudell, J.R.2
Harris, R.A.3
-
88
-
-
30744460111
-
Accessibility to residues in transmembrane segment four of the glycine receptor
-
Lobo IA, Trudell JR, Harris RA (2006) Accessibility to residues in transmembrane segment four of the glycine receptor. Neuropharmacology 50(2):174-181.
-
(2006)
Neuropharmacology
, vol.50
, Issue.2
, pp. 174-181
-
-
Lobo, I.A.1
Trudell, J.R.2
Harris, R.A.3
-
89
-
-
0023132940
-
The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart
-
Logothetis DE, Kurachi Y, Galper J, Neer EJ, Clapham DE (1987) The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Nature 325(6102):321-326.
-
(1987)
Nature
, vol.325
, Issue.6102
, pp. 321-326
-
-
Logothetis, D.E.1
Kurachi, Y.2
Galper, J.3
Neer, E.J.4
Clapham, D.E.5
-
90
-
-
23244456428
-
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
-
Long SB, Campbell EB, Mackinnon R (2005) Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309(5736):897-903.
-
(2005)
Science
, vol.309
, Issue.5736
, pp. 897-903
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
91
-
-
34347354387
-
Dual regulation of TRPV1 by phosphoinositides
-
Lukacs V, Thyagarajan B, Varnai P, Balla A, Balla T, Rohacs T (2007) Dual regulation of TRPV1 by phosphoinositides. J Neurosci 27(26):7070-7080.
-
(2007)
J Neurosci
, vol.27
, Issue.26
, pp. 7070-7080
-
-
Lukacs, V.1
Thyagarajan, B.2
Varnai, P.3
Balla, A.4
Balla, T.5
Rohacs, T.6
-
92
-
-
77951498231
-
Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease
-
Lüscher C, Slesinger PA (2010) Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. Nat Rev Neurosci 11(5):301-315.
-
(2010)
Nat Rev Neurosci
, vol.11
, Issue.5
, pp. 301-315
-
-
Lüscher, C.1
Slesinger, P.A.2
-
93
-
-
20144371097
-
The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin
-
Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A (2005) The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol 15(10):929-934.
-
(2005)
Curr Biol
, vol.15
, Issue.10
, pp. 929-934
-
-
Macpherson, L.J.1
Geierstanger, B.H.2
Viswanath, V.3
Bandell, M.4
Eid, S.R.5
Hwang, S.6
Patapoutian, A.7
-
94
-
-
0029814174
-
A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors
-
Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA (1996) A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Mol Pharmacol 50(2):402-406.
-
(1996)
Mol Pharmacol
, vol.50
, Issue.2
, pp. 402-406
-
-
Mascia, M.P.1
Mihic, S.J.2
Valenzuela, C.F.3
Schofield, P.R.4
Harris, R.A.5
-
95
-
-
0034255021
-
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels
-
Mascia MP, Trudell JR, Harris RA (2000) Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proc Natl Acad Sci USA 97(16):9305-9310.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.16
, pp. 9305-9310
-
-
Mascia, M.P.1
Trudell, J.R.2
Harris, R.A.3
-
96
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346(6284):561-564.
-
(1990)
Nature
, vol.346
, Issue.6284
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
97
-
-
47249119606
-
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation
-
Matta JA, Cornett PM, Miyares RL, Abe K, Sahibzada N, Ahern GP (2008) General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. Proc Natl Acad Sci USA 105(25):8784-8789.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.25
, pp. 8784-8789
-
-
Matta, J.A.1
Cornett, P.M.2
Miyares, R.L.3
Abe, K.4
Sahibzada, N.5
Ahern, G.P.6
-
98
-
-
0037435920
-
Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons
-
McCool BA, Frye GD, Pulido MD, Botting SK (2003) Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons. Brain Res 963(1-2):165-177.
-
(2003)
Brain Res
, vol.963
, Issue.1-2
, pp. 165-177
-
-
McCool, B.A.1
Frye, G.D.2
Pulido, M.D.3
Botting, S.K.4
-
99
-
-
77954947815
-
Linking of glycine receptor transmembrane segments three and four allows assignment of intrasubunit-facing residues
-
McCracken LM, McCracken ML, Gong DH, Trudell JR, Harris RA (2010) Linking of glycine receptor transmembrane segments three and four allows assignment of intrasubunit-facing residues. ACS Chem Neurosci 1(7):482-494.
-
(2010)
ACS Chem Neurosci
, vol.1
, Issue.7
, pp. 482-494
-
-
McCracken, L.M.1
McCracken, M.L.2
Gong, D.H.3
Trudell, J.R.4
Harris, R.A.5
-
100
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy DD, Neuhausser WM, Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416(6876):52-58.
-
(2002)
Nature
, vol.416
, Issue.6876
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
101
-
-
1842328604
-
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
-
Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL (1997) Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 389(6649):385-389.
-
(1997)
Nature
, vol.389
, Issue.6649
, pp. 385-389
-
-
Mihic, S.J.1
Ye, Q.2
Wick, M.J.3
Koltchine, V.V.4
Krasowski, M.D.5
Finn, S.E.6
Mascia, M.P.7
Valenzuela, C.F.8
Hanson, K.K.9
Greenblatt, E.P.10
Harris, R.A.11
Harrison, N.L.12
-
102
-
-
77949560003
-
Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains
-
Misonou H (2010) Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains. Neuroscientist 16(1):51-64.
-
(2010)
Neuroscientist
, vol.16
, Issue.1
, pp. 51-64
-
-
Misonou, H.1
-
103
-
-
44949205447
-
Structure of TRPV1 channel revealed by electron cryomicroscopy
-
Moiseenkova-Bell VY, Stanciu LA, Serysheva II, Tobe BJ, Wensel TG (2008) Structure of TRPV1 channel revealed by electron cryomicroscopy. Proc Natl Acad Sci USA 105(21):7451-7455.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.21
, pp. 7451-7455
-
-
Moiseenkova-Bell, V.Y.1
Stanciu, L.A.2
Serysheva, I.I.3
Tobe, B.J.4
Wensel, T.G.5
-
104
-
-
33846062865
-
The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats
-
Molander A, Lidö HH, Löf E, Ericson M, Söderpalm B (2007) The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats. Alcohol Alcohol 42(1):11-18.
-
(2007)
Alcohol Alcohol
, vol.42
, Issue.1
, pp. 11-18
-
-
Molander, A.1
Lidö, H.H.2
Löf, E.3
Ericson, M.4
Söderpalm, B.5
-
105
-
-
77953152485
-
Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics
-
Mowrey D, Haddadian EJ, Liu LT, Willenbring D, Xu Y, Tang P (2010) Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics. J Phys Chem B 114(22):7649-7655.
-
(2010)
J Phys Chem B
, vol.114
, Issue.22
, pp. 7649-7655
-
-
Mowrey, D.1
Haddadian, E.J.2
Liu, L.T.3
Willenbring, D.4
Xu, Y.5
Tang, P.6
-
106
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL, Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365(6441):61-65.
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
107
-
-
79959652664
-
Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor
-
Murail S, Wallner B, Trudell JR, Bertaccini E, Lindahl E (2011) Microsecond simulations indicate that ethanol binds between subunits and could stabilize an open-state model of a glycine receptor. Biophys J 100:1642-1650.
-
(2011)
Biophys J
, vol.100
, pp. 1642-1650
-
-
Murail, S.1
Wallner, B.2
Trudell, J.R.3
Bertaccini, E.4
Lindahl, E.5
-
108
-
-
34250740367
-
Protein kinase C and alcohol addiction
-
Newton PM, Ron D (2007) Protein kinase C and alcohol addiction. Pharmacol Res 55(6):570-577.
-
(2007)
Pharmacol Res
, vol.55
, Issue.6
, pp. 570-577
-
-
Newton, P.M.1
Ron, D.2
-
109
-
-
34548386717
-
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera
-
Nishida M, Cadene M, Chait BT, Mackinnon R (2007) Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J 26(17):4005-4015.
-
(2007)
EMBO J
, vol.26
, Issue.17
, pp. 4005-4015
-
-
Nishida, M.1
Cadene, M.2
Chait, B.T.3
Mackinnon, R.4
-
110
-
-
0037184996
-
Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution
-
Nishida M, MacKinnon R (2002) Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution. Cell 111(7):957-965.
-
(2002)
Cell
, vol.111
, Issue.7
, pp. 957-965
-
-
Nishida, M.1
MacKinnon, R.2
-
111
-
-
0038609734
-
Structural determinant of TRPV1 desensitization interacts with calmodulin
-
Numazaki M, Tominaga T, Takeuchi K, Murayama N, Toyooka H, Tominaga M (2003) Structural determinant of TRPV1 desensitization interacts with calmodulin. Proc Natl Acad Sci USA 100(13):8002-8006.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.13
, pp. 8002-8006
-
-
Numazaki, M.1
Tominaga, T.2
Takeuchi, K.3
Murayama, N.4
Toyooka, H.5
Tominaga, M.6
-
112
-
-
77950868175
-
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue
-
Nury H, Poitevin F, Van Renterghem C, Changeux J-P, Corringer P-J, Delarue M, Baaden M (2010) One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc Natl Acad Sci USA 107(14):6275-6280.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.14
, pp. 6275-6280
-
-
Nury, H.1
Poitevin, F.2
Van Renterghem, C.3
Changeux, J.-P.4
Corringer, P.-J.5
Delarue, M.6
Baaden, M.7
-
113
-
-
33746047139
-
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1
-
Pegan S, Arrabit C, Slesinger PA, Choe S (2006) Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1. Biochemistry 45(28):8599-8606.
-
(2006)
Biochemistry
, vol.45
, Issue.28
, pp. 8599-8606
-
-
Pegan, S.1
Arrabit, C.2
Slesinger, P.A.3
Choe, S.4
-
114
-
-
14544298750
-
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification
-
Pegan S, Arrabit C, Zhou W, Kwiatkowski W, Collins A, Slesinger PA, Choe S (2005) Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. Nat Neurosci 8(3):279-287.
-
(2005)
Nat Neurosci
, vol.8
, Issue.3
, pp. 279-287
-
-
Pegan, S.1
Arrabit, C.2
Zhou, W.3
Kwiatkowski, W.4
Collins, A.5
Slesinger, P.A.6
Choe, S.7
-
115
-
-
0033580095
-
Differential alcohol modulation of GABA(A) and NMDA receptors
-
Peoples RW, Weight FF (1999) Differential alcohol modulation of GABA(A) and NMDA receptors. Neuroreport 10(1):97-101.
-
(1999)
Neuroreport
, vol.10
, Issue.1
, pp. 97-101
-
-
Peoples, R.W.1
Weight, F.F.2
-
116
-
-
0034808762
-
Recent advances in our understanding of rhodopsin and phototransduction
-
Pepe IM (2001) Recent advances in our understanding of rhodopsin and phototransduction. Prog Retin Eye Res 20(6):733-759.
-
(2001)
Prog Retin Eye Res
, vol.20
, Issue.6
, pp. 733-759
-
-
Pepe, I.M.1
-
117
-
-
48249132803
-
Targets for ethanol action and antagonism in loop 2 of the extracellular domain of glycine receptors
-
Perkins DI, Trudell JR, Crawford DK, Alkana RL, Davies DL (2008) Targets for ethanol action and antagonism in loop 2 of the extracellular domain of glycine receptors. J Neurochem 106(3):1337-1349.
-
(2008)
J Neurochem
, vol.106
, Issue.3
, pp. 1337-1349
-
-
Perkins, D.I.1
Trudell, J.R.2
Crawford, D.K.3
Alkana, R.L.4
Davies, D.L.5
-
118
-
-
77953621828
-
Molecular targets and mechanisms for ethanol action in glycine receptors
-
Perkins DI, Trudell JR, Crawford DK, Alkana RL, Davies DL (2010) Molecular targets and mechanisms for ethanol action in glycine receptors. Pharmacol Ther 127(1):53-65.
-
(2010)
Pharmacol Ther
, vol.127
, Issue.1
, pp. 53-65
-
-
Perkins, D.I.1
Trudell, J.R.2
Crawford, D.K.3
Alkana, R.L.4
Davies, D.L.5
-
119
-
-
70350442576
-
Loop 2 structure in glycine and GABA(A) receptors plays a key role in determining ethanol sensitivity
-
Perkins DI, Trudell JR, Crawford DK, Asatryan L, Alkana RL, Davies DL (2009) Loop 2 structure in glycine and GABA(A) receptors plays a key role in determining ethanol sensitivity. J Biol Chem 284(40):27304-27314.
-
(2009)
J Biol Chem
, vol.284
, Issue.40
, pp. 27304-27314
-
-
Perkins, D.I.1
Trudell, J.R.2
Crawford, D.K.3
Asatryan, L.4
Alkana, R.L.5
Davies, D.L.6
-
120
-
-
72049095578
-
Conformational changes and catalysis by alcohol dehydrogenase
-
Plapp BV (2010) Conformational changes and catalysis by alcohol dehydrogenase. Arch Biochem Biophys 493(1):3-12.
-
(2010)
Arch Biochem Biophys
, vol.493
, Issue.1
, pp. 3-12
-
-
Plapp, B.V.1
-
121
-
-
0031011176
-
Alcohol, tobacco and cannabis use among Nova Scotia adolescents: implications for prevention and harm reduction
-
Poulin C, Elliott D (1997) Alcohol, tobacco and cannabis use among Nova Scotia adolescents: implications for prevention and harm reduction. CMAJ 156(10):1387-1393.
-
(1997)
CMAJ
, vol.156
, Issue.10
, pp. 1387-1393
-
-
Poulin, C.1
Elliott, D.2
-
122
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408(6815):985-990.
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
123
-
-
0037799198
-
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity
-
Prescott ED, Julius D (2003) A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300(5623):1284-1288.
-
(2003)
Science
, vol.300
, Issue.5623
, pp. 1284-1288
-
-
Prescott, E.D.1
Julius, D.2
-
124
-
-
0028322077
-
Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits
-
Reuveny E, Slesinger PA, Inglese J, Morales JM, Iñiguez-Lluhi JA, Lefkowitz RJ, Bourne HR, Jan YN, Jan LY (1994) Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature 370(6485):143-146.
-
(1994)
Nature
, vol.370
, Issue.6485
, pp. 143-146
-
-
Reuveny, E.1
Slesinger, P.A.2
Inglese, J.3
Morales, J.M.4
Iñiguez-Lluhi, J.A.5
Lefkowitz, R.J.6
Bourne, H.R.7
Jan, Y.N.8
Jan, L.Y.9
-
125
-
-
0347723780
-
Ca2+/calmodulin modulates TRPV1 activation by capsaicin
-
Rosenbaum T, Gordon-Shaag A, Munari M, Gordon SE (2004) Ca2+/calmodulin modulates TRPV1 activation by capsaicin. J Gen Physiol 123(1):53-62.
-
(2004)
J Gen Physiol
, vol.123
, Issue.1
, pp. 53-62
-
-
Rosenbaum, T.1
Gordon-Shaag, A.2
Munari, M.3
Gordon, S.E.4
-
126
-
-
0034744617
-
Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels
-
Sadja R, Smadja K, Alagem N, Reuveny E (2001) Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels. Neuron 29(3):669-680.
-
(2001)
Neuron
, vol.29
, Issue.3
, pp. 669-680
-
-
Sadja, R.1
Smadja, K.2
Alagem, N.3
Reuveny, E.4
-
127
-
-
0027216340
-
Inhibition of protein kinase C by alcohols and anaesthetics
-
Slater SJ, Cox KJ, Lombardi JV, Ho C, Kelly MB, Rubin E, Stubbs CD (1993) Inhibition of protein kinase C by alcohols and anaesthetics. Nature 364(6432):82-84.
-
(1993)
Nature
, vol.364
, Issue.6432
, pp. 82-84
-
-
Slater, S.J.1
Cox, K.J.2
Lombardi, J.V.3
Ho, C.4
Kelly, M.B.5
Rubin, E.6
Stubbs, C.D.7
-
128
-
-
0030934651
-
Interaction of alcohols and anesthetics with protein kinase Calpha
-
Slater SJ, Kelly MB, Larkin JD, Ho C, Mazurek A, Taddeo FJ, Yeager MD, Stubbs CD (1997) Interaction of alcohols and anesthetics with protein kinase Calpha. J Biol Chem 272(10):6167-6173.
-
(1997)
J Biol Chem
, vol.272
, Issue.10
, pp. 6167-6173
-
-
Slater, S.J.1
Kelly, M.B.2
Larkin, J.D.3
Ho, C.4
Mazurek, A.5
Taddeo, F.J.6
Yeager, M.D.7
Stubbs, C.D.8
-
129
-
-
2942562190
-
The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha
-
Slater SJ, Malinowski SA, Stubbs CD (2004) The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha. Biochemistry 43(23):7601-7609.
-
(2004)
Biochemistry
, vol.43
, Issue.23
, pp. 7601-7609
-
-
Slater, S.J.1
Malinowski, S.A.2
Stubbs, C.D.3
-
130
-
-
33750524257
-
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
-
Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, Gordon SE (2006) Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol 128(5):509-522.
-
(2006)
J Gen Physiol
, vol.128
, Issue.5
, pp. 509-522
-
-
Stein, A.T.1
Ufret-Vincenty, C.A.2
Hua, L.3
Santana, L.F.4
Gordon, S.E.5
-
131
-
-
77956807049
-
Modulation of single-channel properties of TRPV1 by phosphorylation
-
Studer M, McNaughton PA (2010) Modulation of single-channel properties of TRPV1 by phosphorylation. J Physiol 588(19):3743-3756.
-
(2010)
J Physiol
, vol.588
, Issue.19
, pp. 3743-3756
-
-
Studer, M.1
McNaughton, P.A.2
-
132
-
-
0036326314
-
Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol
-
Sundstrom-Poromaa I, Smith DH, Gong QH, Sabado TN, Li X, Light A, Wiedmann M, Williams K, Smith SS (2002) Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. Nat Neurosci 5(8):721-722.
-
(2002)
Nat Neurosci
, vol.5
, Issue.8
, pp. 721-722
-
-
Sundstrom-Poromaa, I.1
Smith, D.H.2
Gong, Q.H.3
Sabado, T.N.4
Li, X.5
Light, A.6
Wiedmann, M.7
Williams, K.8
Smith, S.S.9
-
133
-
-
0030097740
-
Effect of 12 atmospheres helium-oxygen on the response of mice to convulsant drugs
-
Syapin PJ, Jones BL, Finn DA, Davies DL, Alkana RL (1996) Effect of 12 atmospheres helium-oxygen on the response of mice to convulsant drugs. Undersea Hyperb Med 23(1):35-41.
-
(1996)
Undersea Hyperb Med
, vol.23
, Issue.1
, pp. 35-41
-
-
Syapin, P.J.1
Jones, B.L.2
Finn, D.A.3
Davies, D.L.4
Alkana, R.L.5
-
134
-
-
22244438519
-
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism
-
Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP (2005) Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys J 88:3954-3965.
-
(2005)
Biophys J
, vol.88
, pp. 3954-3965
-
-
Taly, A.1
Delarue, M.2
Grutter, T.3
Nilges, M.4
Le Novère, N.5
Corringer, P.J.6
Changeux, J.P.7
-
135
-
-
77952377218
-
Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation
-
Todorovic J, Welsh BT, Bertaccini EJ, Trudell JR, Mihic SJ (2010) Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation. Proc Natl Acad Sci USA 107(17):7987-7992.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.17
, pp. 7987-7992
-
-
Todorovic, J.1
Welsh, B.T.2
Bertaccini, E.J.3
Trudell, J.R.4
Mihic, S.J.5
-
136
-
-
85047696992
-
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
-
Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D, Smith GD, Randall AD, Harrison S, Bianchi A, Davis JB, Geppetti P (2002) Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci 5(6):546-551.
-
(2002)
Nat Neurosci
, vol.5
, Issue.6
, pp. 546-551
-
-
Trevisani, M.1
Smart, D.2
Gunthorpe, M.J.3
Tognetto, M.4
Barbieri, M.5
Campi, B.6
Amadesi, S.7
Gray, J.8
Jerman, J.C.9
Brough, S.J.10
Owen, D.11
Smith, G.D.12
Randall, A.D.13
Harrison, S.14
Bianchi, A.15
Davis, J.B.16
Geppetti, P.17
-
137
-
-
1642453924
-
Are sobriety and consciousness determined by water in protein cavities?
-
Trudell JR, Harris RA (2004) Are sobriety and consciousness determined by water in protein cavities? Alcohol Clin Exp Res 28(1):1-3.
-
(2004)
Alcohol Clin Exp Res
, vol.28
, Issue.1
, pp. 1-3
-
-
Trudell, J.R.1
Harris, R.A.2
-
138
-
-
27344454932
-
GROMACS: fast, flexible, and free
-
van der Spoel D, Lindahl E, Hess B, Groenhof G, Mark AE, Berendsen HJ (2005) GROMACS: fast, flexible, and free. J Comput Chem 26:1701-1718.
-
(2005)
J Comput Chem
, vol.26
, pp. 1701-1718
-
-
van der Spoel, D.1
Lindahl, E.2
Hess, B.3
Groenhof, G.4
Mark, A.E.5
Berendsen, H.J.6
-
139
-
-
2442636258
-
Endovanilloids putative endogenous ligands of transient receptor potential vanilloid 1 channels
-
van der Stelt M, Di Marzo V (2004) Endovanilloids putative endogenous ligands of transient receptor potential vanilloid 1 channels. Eur J Biochem 271:1827-1834.
-
(2004)
Eur J Biochem
, vol.271
, pp. 1827-1834
-
-
van der Stelt, M.1
Di Marzo, V.2
-
140
-
-
75449085550
-
Computational studies on the interactions of inhalational anesthetics with proteins
-
Vemparala S, Domene C, Klein ML (2010) Computational studies on the interactions of inhalational anesthetics with proteins. Acc Chem Res 43(1):103-110.
-
(2010)
Acc Chem Res
, vol.43
, Issue.1
, pp. 103-110
-
-
Vemparala, S.1
Domene, C.2
Klein, M.L.3
-
141
-
-
43449130407
-
Neuropharmacology of alcohol addiction
-
Vengeliene V, Bilbao A, Molander A, Spanagel R (2008) Neuropharmacology of alcohol addiction. Br J Pharmacol 154(2):299-315.
-
(2008)
Br J Pharmacol
, vol.154
, Issue.2
, pp. 299-315
-
-
Vengeliene, V.1
Bilbao, A.2
Molander, A.3
Spanagel, R.4
-
142
-
-
39749183495
-
Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol
-
Vetter I, Wyse BD, Roberts-Thomson SJ, Monteith GR, Cabot PJ (2008) Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol. Eur J Pain 12(4):441-454.
-
(2008)
Eur J Pain
, vol.12
, Issue.4
, pp. 441-454
-
-
Vetter, I.1
Wyse, B.D.2
Roberts-Thomson, S.J.3
Monteith, G.R.4
Cabot, P.J.5
-
143
-
-
0037443098
-
Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1
-
Vlachová V, Teisinger J, Susánková K, Lyfenko A, Ettrich R, Vyklický L (2003) Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1. J Neurosci 23:1340-1350.
-
(2003)
J Neurosci
, vol.23
, pp. 1340-1350
-
-
Vlachová, V.1
Teisinger, J.2
Susánková, K.3
Lyfenko, A.4
Ettrich, R.5
Vyklický, L.6
-
144
-
-
0034008744
-
The use of Xenopus laevis oocytes for the functional characterization of heterologously expressed membrane proteins
-
Wagner CA, Friedrich B, Setiawan I, Lang F, Bröer S (2000) The use of Xenopus laevis oocytes for the functional characterization of heterologously expressed membrane proteins. Cell Physiol Biochem 10(1-2):1-12.
-
(2000)
Cell Physiol Biochem
, vol.10
, Issue.1-2
, pp. 1-12
-
-
Wagner, C.A.1
Friedrich, B.2
Setiawan, I.3
Lang, F.4
Bröer, S.5
-
145
-
-
77951217455
-
Distinct modulations of human capsaicin receptor by protons and magnesium through different domains
-
Wang S, Poon K, Oswald RE, Chuang H-H (2010) Distinct modulations of human capsaicin receptor by protons and magnesium through different domains. J Biol Chem 285(15):11547-11556.
-
(2010)
J Biol Chem
, vol.285
, Issue.15
, pp. 11547-11556
-
-
Wang, S.1
Poon, K.2
Oswald, R.E.3
Chuang, H.-H.4
-
146
-
-
4644326916
-
Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons
-
Wei W, Faria LC, Mody I (2004) Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons. J Neurosci 24(38):8379-8382.
-
(2004)
J Neurosci
, vol.24
, Issue.38
, pp. 8379-8382
-
-
Wei, W.1
Faria, L.C.2
Mody, I.3
-
147
-
-
23044500197
-
Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8
-
Weil A, Moore SE, Waite NJ, Randall A, Gunthorpe MJ (2005) Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8. Mol Pharmacol 68(2):518-527.
-
(2005)
Mol Pharmacol
, vol.68
, Issue.2
, pp. 518-527
-
-
Weil, A.1
Moore, S.E.2
Waite, N.J.3
Randall, A.4
Gunthorpe, M.J.5
-
148
-
-
58149089145
-
Can morphing methods predict intermediate structures?
-
Weiss DR, Levitt M (2009) Can morphing methods predict intermediate structures? J Mol Biol 385(2):665-674.
-
(2009)
J Mol Biol
, vol.385
, Issue.2
, pp. 665-674
-
-
Weiss, D.R.1
Levitt, M.2
-
149
-
-
0034610391
-
The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat
-
Welch JM, Simon SA, Reinhart PH (2000) The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat. Proc Natl Acad Sci USA 97(25):13889-13894.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.25
, pp. 13889-13894
-
-
Welch, J.M.1
Simon, S.A.2
Reinhart, P.H.3
-
150
-
-
0032568547
-
Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor?
-
Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA (1998) Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proc Natl Acad Sci USA 95(11):6504-6509.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6504-6509
-
-
Wick, M.J.1
Mihic, S.J.2
Ueno, S.3
Mascia, M.P.4
Trudell, J.R.5
Brozowski, S.J.6
Ye, Q.7
Harrison, N.L.8
Harris, R.A.9
-
151
-
-
0033551765
-
Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors
-
Yamakura T, Mihic SJ, Harris RA (1999) Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors. J Biol Chem 274(33):23006-23012.
-
(1999)
J Biol Chem
, vol.274
, Issue.33
, pp. 23006-23012
-
-
Yamakura, T.1
Mihic, S.J.2
Harris, R.A.3
-
152
-
-
41149122203
-
Dopamine and ethanol cause translocation of epsilonPKC associated with epsilonRACK: cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways
-
Yao L, Fan P, Jiang Z, Gordon A, Mochly-Rosen D, Diamond I (2008) Dopamine and ethanol cause translocation of epsilonPKC associated with epsilonRACK: cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways. Mol Pharmacol 73(4):1105-1112.
-
(2008)
Mol Pharmacol
, vol.73
, Issue.4
, pp. 1105-1112
-
-
Yao, L.1
Fan, P.2
Jiang, Z.3
Gordon, A.4
Mochly-Rosen, D.5
Diamond, I.6
-
153
-
-
0032488831
-
Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267
-
Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA (1998) Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. J Biol Chem 273(6):3314-3319.
-
(1998)
J Biol Chem
, vol.273
, Issue.6
, pp. 3314-3319
-
-
Ye, Q.1
Koltchine, V.V.2
Mihic, S.J.3
Mascia, M.P.4
Wick, M.J.5
Finn, S.E.6
Harrison, N.L.7
Harris, R.A.8
-
154
-
-
0035049090
-
Yeast screen for constitutively active mutant G protein-activated potassium channels
-
Yi BA, Lin YF, Jan YN, Jan LY (2001) Yeast screen for constitutively active mutant G protein-activated potassium channels. Neuron 29(3):657-667.
-
(2001)
Neuron
, vol.29
, Issue.3
, pp. 657-667
-
-
Yi, B.A.1
Lin, Y.F.2
Jan, Y.N.3
Jan, L.Y.4
-
155
-
-
72249097775
-
Gating transition of pentameric ligand-gated ion channels
-
Zhu F, Hummer G (2009) Gating transition of pentameric ligand-gated ion channels. Biophys J 97(9):2456-2463.
-
(2009)
Biophys J
, vol.97
, Issue.9
, pp. 2456-2463
-
-
Zhu, F.1
Hummer, G.2
-
156
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sørgård M, Di Marzo V, Julius D, Högestätt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400(6743):452-457.
-
(1999)
Nature
, vol.400
, Issue.6743
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sørgård, M.5
Di Marzo, V.6
Julius, D.7
Högestätt, E.D.8
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