An outline of desensitization in pentameric ligand-gated ion channel receptors

Cellular and Molecular Life Sciences

Volumn 70, Issue 7, 2013, Pages 1241-1253

  Keramidas, Angelo ^a   Lynch, Joseph W ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

5 HT; Acetylcholine; Electrophysiology; GABA; Glycine; Ligand gated ion channel; Single channel kinetics

Indexed keywords

LIGAND GATED ION CHANNEL; LIGAND GATED ION CHANNEL RECEPTOR; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HYDROPHOBICITY; LIGAND BINDING; MEMBRANE STRUCTURE; PROTEIN CONFORMATION; PROTEIN DOMAIN; RECEPTOR DOWN REGULATION; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; DRUG RESISTANCE; HUMANS; ION CHANNEL GATING; LIGAND-GATED ION CHANNELS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

EID: 84876681700     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1133-z     Document Type: Review

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