Single-channel current through nicotinic receptor produced by closure of binding site C-loop

Biophysical Journal

Volumn 96, Issue 9, 2009, Pages 3582-3590

  Wang, Hai Long ^a   Toghraee, Reza ^c   Papke, David ^c   Cheng, Xiao Lin ^d   McCammon, J Andrew ^e   Ravaioli, Umberto ^c   Sine, Steven M ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b Mayo Clinic   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d OAK RIDGE NATIONAL LABORATORY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; ION; NICOTINIC RECEPTOR; CALCIUM; CHLORIDE; MAGNESIUM; NICOTINIC AGENT; POTASSIUM; SODIUM; WATER;

AGONIST; ARTICLE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; DESMOSOME; EMBRYO; HUMAN; HUMAN CELL; ION CONDUCTANCE; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; MONTE CARLO METHOD; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SIMULATION; SIMULATOR; ANIMAL; BINDING SITE; CELL LINE; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; ELECTRIC CONDUCTIVITY; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION; THERMODYNAMICS; TORPEDO;

ANIMALS; BINDING SITES; CALCIUM; CELL LINE; CHLORIDES; COMPUTER SIMULATION; ELECTRIC CONDUCTIVITY; HUMANS; MAGNESIUM; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MONTE CARLO METHOD; NICOTINIC AGONISTS; POTASSIUM; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; SODIUM; THERMODYNAMICS; TORPEDO; WATER;

EID: 67650354191     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.02.020     Document Type: Article

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