-
2
-
-
0036891169
-
Unconventional ligands and modulators of nicotinic receptors
-
Pereira E.F., Hilmas C., Santos M.D., Alkondon M., Maelicke A., and Albuquerque E.X. Unconventional ligands and modulators of nicotinic receptors. J. Neurobiol. 53 (2002) 479-500
-
(2002)
J. Neurobiol.
, vol.53
, pp. 479-500
-
-
Pereira, E.F.1
Hilmas, C.2
Santos, M.D.3
Alkondon, M.4
Maelicke, A.5
Albuquerque, E.X.6
-
4
-
-
0022758905
-
The reaction site of a non-competitive antagonist in the delta-subunit of the nicotinic acetylcholine receptor
-
Oberthur W., Muhn P., Baumann H., Lottspeich F., Wittmann-Liebold B., and Hucho F. The reaction site of a non-competitive antagonist in the delta-subunit of the nicotinic acetylcholine receptor. EMBO J. 5 (1986) 1815-1819
-
(1986)
EMBO J.
, vol.5
, pp. 1815-1819
-
-
Oberthur, W.1
Muhn, P.2
Baumann, H.3
Lottspeich, F.4
Wittmann-Liebold, B.5
Hucho, F.6
-
6
-
-
30744470883
-
Probing ion-channel pores one proton at a time
-
Cymes G.D., Ni Y., and Grosman C. Probing ion-channel pores one proton at a time. Nature 438 (2005) 975-980
-
(2005)
Nature
, vol.438
, pp. 975-980
-
-
Cymes, G.D.1
Ni, Y.2
Grosman, C.3
-
7
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A., Fujiyoshi Y., and Unwin N. Structure and gating mechanism of the acetylcholine receptor pore. Nature 423 (2003) 949-955
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
8
-
-
0026485739
-
Acetylcholine receptor channel structure probed in cysteine-substitution mutants
-
Akabas M.H., Stauffer D.A., Xu M., and Karlin A. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258 (1992) 307-310
-
(1992)
Science
, vol.258
, pp. 307-310
-
-
Akabas, M.H.1
Stauffer, D.A.2
Xu, M.3
Karlin, A.4
-
9
-
-
0033046008
-
The steroid promegestone is a noncompetitive antagonist of the Torpedo nicotinic acetylcholine receptor that interacts with the lipid-protein interface
-
Blanton M.P., Xie Y., Dangott L.J., and Cohen J.B. The steroid promegestone is a noncompetitive antagonist of the Torpedo nicotinic acetylcholine receptor that interacts with the lipid-protein interface. Mol. Pharmacol. 55 (1999) 269-278
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 269-278
-
-
Blanton, M.P.1
Xie, Y.2
Dangott, L.J.3
Cohen, J.B.4
-
10
-
-
0142090758
-
Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants
-
Gumilar F., Arias H.R., Spitzmaul G., and Bouzat C. Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants. Neuropharmacology 45 (2003) 964-976
-
(2003)
Neuropharmacology
, vol.45
, pp. 964-976
-
-
Gumilar, F.1
Arias, H.R.2
Spitzmaul, G.3
Bouzat, C.4
-
11
-
-
0344441288
-
A structural model of agonist binding to the alpha3beta4 neuronal nicotinic receptor
-
Costa V., Nistri A., Cavalli A., and Carloni P. A structural model of agonist binding to the alpha3beta4 neuronal nicotinic receptor. Br. J. Pharmacol. 140 (2003) 921-931
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 921-931
-
-
Costa, V.1
Nistri, A.2
Cavalli, A.3
Carloni, P.4
-
12
-
-
0033922960
-
Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the alpha4 and beta4 subunits
-
Francis M.M., Vazquez R.W., Papke R.L., and Oswald R.E. Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the alpha4 and beta4 subunits. Mol. Pharmacol. 58 (2000) 109-119
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 109-119
-
-
Francis, M.M.1
Vazquez, R.W.2
Papke, R.L.3
Oswald, R.E.4
-
13
-
-
33646177253
-
Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors
-
Arias H.R., Bhumireddy P., and Bouzat C. Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors. Int. J. Biochem. Cell Biol. 38 (2006) 1254-1276
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 1254-1276
-
-
Arias, H.R.1
Bhumireddy, P.2
Bouzat, C.3
-
14
-
-
23944472732
-
Nicotinic agonists, antagonists, and modulators from natural sources
-
Daly J.W. Nicotinic agonists, antagonists, and modulators from natural sources. Cell Mol. Neurobiol. 25 (2005) 513-552
-
(2005)
Cell Mol. Neurobiol.
, vol.25
, pp. 513-552
-
-
Daly, J.W.1
-
15
-
-
0035902187
-
A glia-derived acetylcholine-binding protein that modulates synaptic transmission
-
Smit A.B., Syed N.I., Schaap D., van Minnen J., Klumperman J., Kits K.S., et al. A glia-derived acetylcholine-binding protein that modulates synaptic transmission. Nature 411 (2001) 261-268
-
(2001)
Nature
, vol.411
, pp. 261-268
-
-
Smit, A.B.1
Syed, N.I.2
Schaap, D.3
van Minnen, J.4
Klumperman, J.5
Kits, K.S.6
-
16
-
-
2642560397
-
Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica
-
Hansen S.B., Talley T.T., Radic Z., and Taylor P. Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. J. Biol. Chem. 279 (2004) 24197-24202
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24197-24202
-
-
Hansen, S.B.1
Talley, T.T.2
Radic, Z.3
Taylor, P.4
-
17
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
Bouzat C., Gumilar F., Spitzmaul G., Wang H.L., Rayes D., Hansen S.B., et al. Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature 430 (2004) 896-900
-
(2004)
Nature
, vol.430
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
-
18
-
-
14844300820
-
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
-
Gao F., Bren N., Burghardt T.P., Hansen S., Henchman R.H., Taylor P., et al. Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. J. Biol. Chem. 280 (2005) 8443-8451
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8443-8451
-
-
Gao, F.1
Bren, N.2
Burghardt, T.P.3
Hansen, S.4
Henchman, R.H.5
Taylor, P.6
-
19
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
Celie P.H., van Rossum-Fikkert S.E., van Dijk W.J., Brejc K., Smit A.B., and Sixma T.K. Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron 41 (2004) 907-914
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.1
van Rossum-Fikkert, S.E.2
van Dijk, W.J.3
Brejc, K.4
Smit, A.B.5
Sixma, T.K.6
-
20
-
-
0038771238
-
Comparative modeling of GABA(A) receptors: limits, insights, future developments
-
Ernst M., Brauchart D., Boresch S., and Sieghart W. Comparative modeling of GABA(A) receptors: limits, insights, future developments. Neuroscience 119 (2003) 933-943
-
(2003)
Neuroscience
, vol.119
, pp. 933-943
-
-
Ernst, M.1
Brauchart, D.2
Boresch, S.3
Sieghart, W.4
-
21
-
-
33748939932
-
Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop
-
Gao F., Mer G., Tonelli M., Hansen S.B., Burghardt T.P., Taylor P., and Sine S.M. Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Mol. Pharmacol. 70 (2006) 1230-1235
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 1230-1235
-
-
Gao, F.1
Mer, G.2
Tonelli, M.3
Hansen, S.B.4
Burghardt, T.P.5
Taylor, P.6
Sine, S.M.7
-
22
-
-
10744232323
-
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
-
Samochocki M., Hoffle A., Fehrenbacher A., Jostock R., Ludwig J., Christner C., et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J. Pharmacol. Exp. Ther. 305 (2003) 1024-1036
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 1024-1036
-
-
Samochocki, M.1
Hoffle, A.2
Fehrenbacher, A.3
Jostock, R.4
Ludwig, J.5
Christner, C.6
-
23
-
-
33645095976
-
Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits
-
Sarto-Jackson I., Ramerstorfer J., Ernst M., and Sieghart W. Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits. J. Neurochem. 96 (2006) 983-995
-
(2006)
J. Neurochem.
, vol.96
, pp. 983-995
-
-
Sarto-Jackson, I.1
Ramerstorfer, J.2
Ernst, M.3
Sieghart, W.4
-
24
-
-
0033616681
-
Modulation of nicotinic acetylcholine receptors by strychnine
-
Garcia-Colunga J., and Miledi R. Modulation of nicotinic acetylcholine receptors by strychnine. Proc. Natl Acad. Sci. USA 96 (1999) 4113-4118
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 4113-4118
-
-
Garcia-Colunga, J.1
Miledi, R.2
-
25
-
-
0031888644
-
Strychnine: a potent competitive antagonist of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons
-
Matsubayashi H., Alkondon M., Pereira E.F., Swanson K.L., and Albuquerque E.X. Strychnine: a potent competitive antagonist of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. J. Pharmacol. Exp. Ther. 284 (1998) 904-913
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 904-913
-
-
Matsubayashi, H.1
Alkondon, M.2
Pereira, E.F.3
Swanson, K.L.4
Albuquerque, E.X.5
-
26
-
-
0027171322
-
Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine
-
Schrattenholz A., Godovac-Zimmermann J., Schafer H.J., Albuquerque E.X., and Maelicke A. Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine. Eur. J. Biochem. 216 (1993) 671-677
-
(1993)
Eur. J. Biochem.
, vol.216
, pp. 671-677
-
-
Schrattenholz, A.1
Godovac-Zimmermann, J.2
Schafer, H.J.3
Albuquerque, E.X.4
Maelicke, A.5
-
27
-
-
0025808153
-
A second pathway of activation of the Torpedo acetylcholine receptor channel
-
Okonjo K.O., Kuhlmann J., and Maelicke A. A second pathway of activation of the Torpedo acetylcholine receptor channel. Eur. J. Biochem. 200 (1991) 671-677
-
(1991)
Eur. J. Biochem.
, vol.200
, pp. 671-677
-
-
Okonjo, K.O.1
Kuhlmann, J.2
Maelicke, A.3
-
28
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen S.B., Sulzenbacher G., Huxford T., Marchot P., Taylor P., and Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J. 24 (2005) 3635-3646
-
(2005)
EMBO J.
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
29
-
-
0019182078
-
The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin
-
Sine S.M., and Taylor P. The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin. J. Biol. Chem. 255 (1980) 10144-10156
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 10144-10156
-
-
Sine, S.M.1
Taylor, P.2
-
30
-
-
0033136270
-
lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS
-
Miwa J.M., Ibanez-Tallon I., Crabtree G.W., Sanchez R., Sali A., Role L.W., and Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron 23 (1999) 105-114
-
(1999)
Neuron
, vol.23
, pp. 105-114
-
-
Miwa, J.M.1
Ibanez-Tallon, I.2
Crabtree, G.W.3
Sanchez, R.4
Sali, A.5
Role, L.W.6
Heintz, N.7
-
31
-
-
0037109074
-
Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
-
Reeves P.J., Callewaert N., Contreras R., and Khorana H.G. Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proc. Natl Acad. Sci. USA 99 (2002) 13419-13424
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 13419-13424
-
-
Reeves, P.J.1
Callewaert, N.2
Contreras, R.3
Khorana, H.G.4
-
32
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276 (1997) 307-326
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
33
-
-
0028103275
-
The CCP4 suite: programs for protein crystallography
-
Collaborative Computing Project Number 4
-
Collaborative Computing Project Number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallog. sect. D 50 (1994) 760-763
-
(1994)
Acta Crystallog. sect. D
, vol.50
, pp. 760-763
-
-
-
34
-
-
84920325457
-
AMoRe: an automated package for molecular replacement
-
Navaza J. AMoRe: an automated package for molecular replacement. Acta Crystallog. sect. A 50 (1994) 157-163
-
(1994)
Acta Crystallog. sect. A
, vol.50
, pp. 157-163
-
-
Navaza, J.1
-
35
-
-
0002705842
-
A visual protein crystallographic software system for X11/XView
-
McRee D. A visual protein crystallographic software system for X11/XView. J. Mol. Graph. 10 (1992) 44-46
-
(1992)
J. Mol. Graph.
, vol.10
, pp. 44-46
-
-
McRee, D.1
-
36
-
-
0030924992
-
Refinement of macromolecular structures by maximum-likelihood method
-
Murshudov G.N., Vagin A.A., and Dodson E.J. Refinement of macromolecular structures by maximum-likelihood method. Acta Crystallog. sect. D 53 (1997) 240-255
-
(1997)
Acta Crystallog. sect. D
, vol.53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
37
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J. Mol. Biol. 346 (2005) 967-989
-
(2005)
J. Mol. Biol.
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
38
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van Der Oost J., Smit A.B., and Sixma T.K. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 411 (2001) 269-276
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
|