A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions

Biological Cybernetics

Volumn 75, Issue 5, 1996, Pages 361-379

  Edelstein, Stuart J ^a,b,d   Schaad, Olivier ^a   Henry, Eric ^c   Bertrand, Daniel ^a   Changeux, Jean Pierre ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b INSTITUT PASTEUR   (France)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d NONE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; NICOTINIC RECEPTOR;

ARTICLE; ARTIFICIAL NEURAL NETWORK; BINDING SITE; BIOLOGICAL MODEL; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMISTRY; COMPUTER SIMULATION; DOSE RESPONSE; KINETICS; PHYSIOLOGY; PROTEIN CONFORMATION; SENSITIVITY AND SPECIFICITY; SYNAPSE;

ALLOSTERIC SITE; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; KINETICS; LIGANDS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; NEURAL NETWORKS (COMPUTER); PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; SENSITIVITY AND SPECIFICITY; SYNAPSES;

EID: 0030281174     PISSN: 03401200     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004220050302     Document Type: Article

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