Photoaffinity labeling the propofol binding site in GLIC

Biochemistry

Volumn 53, Issue 1, 2014, Pages 135-142

  Chiara, David C ^a   Gill, Jonathan F ^a   Chen, Qiang ^b   Tillman, Tommy ^b   Dailey, William P ^c   Eckenhoff, Roderic G ^c   Xu, Yan ^b   Tang, Pei ^b   Cohen, Jonathan B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CURRENT RESPONSE; LIGAND-GATED ION CHANNELS; MICROSEQUENCING; NICOTINIC ACETYLCHOLINE RECEPTORS; PHOTOAFFINITY LABELING; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE HELICES; TRIFLUOROMETHYL;

ANESTHETICS; BINDING SITES;

ACTIVATION ANALYSIS;

2 ISOPROPYL 5 [3 (TRIFLUOROMETHYL) 3H DIAZIRIN 3 YL]PHENOL; 4 AMINOBUTYRIC ACID A RECEPTOR; LIGAND GATED ION CHANNEL; PROPOFOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OOCYTE; PH; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

AFFINITY LABELS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; DIAZOMETHANE; ION CHANNELS; LIGAND-GATED ION CHANNELS; MODELS, MOLECULAR; PROPOFOL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GABA-A;

EID: 84892566635     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401492k     Document Type: Article

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