-
1
-
-
0023821516
-
Identification of a putative regulator of early t cell activation genes
-
Shaw JP, Utz PJ, Durand DB, Toole JJ, Emmel EA, Crabtree GR. Identification of a putative regulator of early T cell activation genes. Science. 1988;241(4862):202-205.
-
(1988)
Science
, vol.241
, Issue.4862
, pp. 202-205
-
-
Shaw, J.P.1
Utz, P.J.2
Durand, D.B.3
Toole, J.J.4
Emmel, E.A.5
Crabtree, G.R.6
-
2
-
-
77956175013
-
Nfat, immunity and cancer: A transcription factor comes of age
-
Müller MR, Rao A. NFAT, immunity and cancer: a transcription factor comes of age. Nat Rev Immunol. 2010;10(9):645-656.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.9
, pp. 645-656
-
-
Müller, M.R.1
Rao, A.2
-
3
-
-
34247108202
-
Expression analysis of nuclear factor of activated t cells (nfat) during myeloid differentiation of cd341 cells: Regulation of fas ligand gene expression in megakaryocytes
-
Kiani A, Kuithan H, Kuithan F, et al. Expression analysis of nuclear factor of activated T cells (NFAT) during myeloid differentiation of CD341 cells: regulation of Fas ligand gene expression in megakaryocytes. Exp Hematol. 2007;35(5): 757-770.
-
(2007)
Exp Hematol
, vol.35
, Issue.5
, pp. 757-770
-
-
Kiani, A.1
Kuithan, H.2
Kuithan, F.3
-
4
-
-
84856272074
-
Regulation of fas/fas ligand-mediated apoptosis by nuclear factor of activated t cells in megakaryocytes
-
Arabanian LS, Kujawski S, Habermann I, Ehninger G, Kiani A. Regulation of fas/fas ligand-mediated apoptosis by nuclear factor of activated T cells in megakaryocytes. Br J Haematol. 2012; 156(4):523-534.
-
(2012)
Br J Haematol
, vol.156
, Issue.4
, pp. 523-534
-
-
Arabanian, L.S.1
Kujawski, S.2
Habermann, I.3
Ehninger, G.4
Kiani, A.5
-
5
-
-
0037108434
-
Overexpression of fkbp51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors
-
Giraudier S, Chagraoui H, Komura E, et al. Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. Blood. 2002;100(8):2932-2940.
-
(2002)
Blood
, vol.100
, Issue.8
, pp. 2932-2940
-
-
Giraudier, S.1
Chagraoui, H.2
Komura, E.3
-
6
-
-
58649097496
-
Regulation of down syndrome critical region 1 expression by nuclear factor of activated t cells in megakaryocytes
-
Kyttälä S, Habermann I, Minami T, Ehninger G, Kiani A. Regulation of Down Syndrome Critical Region 1 expression by Nuclear Factor of Activated T cells in megakaryocytes. Br J Haematol. 2009;144(3):395-408.
-
(2009)
Br J Haematol
, vol.144
, Issue.3
, pp. 395-408
-
-
Kyttälä, S.1
Habermann, I.2
Minami, T.3
Ehninger, G.4
Kiani, A.5
-
7
-
-
84857814609
-
Increased dosage of the chromosome 21 ortholog dyrk1a promotes megakaryoblastic leukemia in a murine model of down syndrome
-
Malinge S, Bliss-Moreau M, Kirsammer G, et al. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012;122(3):948-962.
-
(2012)
J Clin Invest
, vol.122
, Issue.3
, pp. 948-962
-
-
Malinge, S.1
Bliss-Moreau, M.2
Kirsammer, G.3
-
8
-
-
0031465970
-
Two nfat transcription factor binding sites participate in the regulation of cd95 (fas) ligand expression in activated human t cells
-
Latinis KM, Norian LA, Eliason SL, Koretzky GA. Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells. J Biol Chem. 1997;272(50):31427-31434.
-
(1997)
J Biol Chem.
, vol.272
, Issue.50
, pp. 31427-31434
-
-
Latinis, K.M.1
Norian, L.A.2
Eliason, S.L.3
Koretzky, G.A.4
-
9
-
-
0036864625
-
Nfatc2-mediated repression of cyclin-dependent kinase 4 expression
-
Baksh S, Widlund HR, Frazer-Abel AA, et al. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Mol Cell. 2002;10(5): 1071-1081.
-
(2002)
Mol Cell
, vol.10
, Issue.5
, pp. 1071-1081
-
-
Baksh, S.1
Widlund, H.R.2
Frazer-Abel, A.A.3
-
10
-
-
38649106497
-
Nfatc1 balances quiescence and proliferation of skin stem cells
-
Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 2008;132(2): 299-310.
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 299-310
-
-
Horsley, V.1
Aliprantis, A.O.2
Polak, L.3
Glimcher, L.H.4
Fuchs, E.5
-
11
-
-
20644466433
-
Nfat proteins: Key regulators of t-cell development and function
-
Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol. 2005;5(6):472-484.
-
(2005)
Nat Rev Immunol.
, vol.5
, Issue.6
, pp. 472-484
-
-
Macian, F.1
-
12
-
-
67649506317
-
Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor dscr1
-
Baek KH, Zaslavsky A, Lynch RC, et al. Down’s syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature. 2009;459(7250):1126-1130.
-
(2009)
Nature
, vol.459
, Issue.7250
, pp. 1126-1130
-
-
Baek, K.H.1
Zaslavsky, A.2
Lynch, R.C.3
-
13
-
-
77957194257
-
Survivin localization during endomitosis of high ploidy mouse megakaryocytes
-
McCrann DJ, Ravid K. Survivin localization during endomitosis of high ploidy mouse megakaryocytes. Blood. 2010;116(12): 2192-2193.
-
(2010)
Blood
, vol.116
, Issue.12
, pp. 2192-2193
-
-
McCrann, D.J.1
Ravid, K.2
-
14
-
-
0029761681
-
Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor Nf-at4
-
Shibasaki F, Price ER, Milan D, McKeon F. Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature. 1996;382(6589):370-373.
-
(1996)
Nature
, vol.382
, Issue.6589
, pp. 370-373
-
-
Shibasaki, F.1
Price, E.R.2
Milan, D.3
McKeon, F.4
-
15
-
-
0035312966
-
Cd9 and megakaryocyte differentiation
-
Clay D, Rubinstein E, Mishal Z, et al. CD9 and megakaryocyte differentiation. Blood. 2001;97(7): 1982-1989.
-
(2001)
Blood
, vol.97
, Issue.7
, pp. 1982-1989
-
-
Clay, D.1
Rubinstein, E.2
Mishal, Z.3
-
16
-
-
0037422537
-
Characterization of mouse clonogenic megakaryocyte progenitors
-
Nakorn TN, Miyamoto T, Weissman IL. Characterization of mouse clonogenic megakaryocyte progenitors. Proc Natl Acad Sci USA. 2003;100(1):205-210.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 205-210
-
-
Nakorn, T.N.1
Miyamoto, T.2
Weissman, I.L.3
-
17
-
-
34848896359
-
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
-
Pronk CJH, Rossi DJ, Månsson R, et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 2007; 1(4):428-442.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.4
, pp. 428-442
-
-
Pronk, C.J.H.1
Rossi, D.J.2
Månsson, R.3
-
18
-
-
84857125323
-
Characterization of thrombopoietin (tpo)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential
-
Ng AP, Kauppi M, Metcalf D, Di Rago L, Hyland CD, Alexander WS. Characterization of thrombopoietin (TPO)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potential. Proc Natl Acad Sci USA. 2012;109(7):2364-2369.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.7
, pp. 2364-2369
-
-
Ng, A.P.1
Kauppi, M.2
Metcalf, D.3
Di Rago, L.4
Hyland, C.D.5
Alexander, W.S.6
-
19
-
-
33746508365
-
Megakaryocyte development and platelet production
-
Deutsch VR, Tomer A. Megakaryocyte development and platelet production. Br J Haematol. 2006;134(5):453-466.
-
(2006)
Br J Haematol.
, vol.134
, Issue.5
, pp. 453-466
-
-
Deutsch, V.R.1
Tomer, A.2
-
20
-
-
34548214756
-
The nfat1 transcription factor is a repressor of cyclin a2 gene expression
-
Carvalho LD, Teixeira LK, Carrossini N, et al. The NFAT1 transcription factor is a repressor of cyclin A2 gene expression. Cell Cycle. 2007;6(14): 1789-1795.
-
(2007)
Cell Cycle
, vol.6
, Issue.14
, pp. 1789-1795
-
-
Carvalho, L.D.1
Teixeira, L.K.2
Carrossini, N.3
-
21
-
-
0036884463
-
Nfatc2 transcription factor regulates cell cycle progression during lymphocyte activation: Evidence of its involvement in the control of cyclin gene expression
-
Caetano MS, Vieira-de-Abreu A, Teixeira LK, Werneck MB, Barcinski MA, Viola JP. NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: evidence of its involvement in the control of cyclin gene expression. FASEB J. 2002;16(14): 1940-1942.
-
(2002)
FASEB J.
, vol.16
, Issue.14
, pp. 1940-1942
-
-
Caetano, M.S.1
Vieira-De-Abreu, A.2
Teixeira, L.K.3
Werneck, M.B.4
Barcinski, M.A.5
Viola, J.P.6
-
22
-
-
58149396964
-
Trisomy 21 enhances human fetal erythro-megakaryocytic development
-
Chou ST, Opalinska JB, Yao Y, et al. Trisomy 21 enhances human fetal erythro-megakaryocytic development. Blood. 2008;112(12):4503-4506.
-
(2008)
Blood
, vol.112
, Issue.12
, pp. 4503-4506
-
-
Chou, S.T.1
Opalinska, J.B.2
Yao, Y.3
-
23
-
-
0026643141
-
Identification of calcineurin as a key signalling enzyme in t-lymphocyte activation
-
Clipstone NA, Crabtree GR. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature. 1992;357(6380): 695-697.
-
(1992)
Nature
, vol.357
, Issue.6380
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
24
-
-
0036234543
-
Nfat signaling: Choreographing the social lives of cells
-
Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 2002;109(Suppl):S67-S79.
-
(2002)
Cell
, vol.109
, pp. S67-S79
-
-
Crabtree, G.R.1
Olson, E.N.2
-
25
-
-
55549112834
-
Selective role of calcineurin in haematopoiesis and lymphopoiesis
-
Gallo EM, Ho L, Winslow MM, Staton TL, Crabtree GR. Selective role of calcineurin in haematopoiesis and lymphopoiesis. EMBO Rep. 2008;9(11):1141-1148.
-
(2008)
EMBO Rep
, vol.9
, Issue.11
, pp. 1141-1148
-
-
Gallo, E.M.1
Ho, L.2
Winslow, M.M.3
Staton, T.L.4
Crabtree, G.R.5
-
26
-
-
43549095989
-
Nuclear factor of activated t cells (nfat) mediates cd154 expression in megakaryocytes
-
Crist SA, Sprague DL, Ratliff TL. Nuclear factor of activated T cells (NFAT) mediates CD154 expression in megakaryocytes. Blood. 2008; 111(7):3553-3561.
-
(2008)
Blood
, vol.111
, Issue.7
, pp. 3553-3561
-
-
Crist, S.A.1
Sprague, D.L.2
Ratliff, T.L.3
-
27
-
-
0343192437
-
Identification and characterization of a highly conserved calcineurin binding protein, cbp1/calcipressin, in cryptococcus neoformans
-
Görlach J, Fox DS, Cutler NS, Cox GM, Perfect JR, Heitman J. Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. EMBO J. 2000;19(14):3618-3629.
-
(2000)
EMBO J.
, vol.19
, Issue.14
, pp. 3618-3629
-
-
Görlach, J.1
Fox, D.S.2
Cutler, N.S.3
Cox, G.M.4
Perfect, J.R.5
Heitman, J.6
-
28
-
-
0034234963
-
A conserved family of calcineurin regulators
-
Kingsbury TJ, Cunningham KW. A conserved family of calcineurin regulators. Genes Dev. 2000; 14(13):1595-1604.
-
(2000)
Genes Dev
, vol.14
, Issue.13
, pp. 1595-1604
-
-
Kingsbury, T.J.1
Cunningham, K.W.2
-
29
-
-
0037237668
-
The role of modulatory calcineurin-interacting proteins in calcineurin signaling
-
Rothermel BA, Vega RB, Williams RS. The role of modulatory calcineurin-interacting proteins in calcineurin signaling. Trends Cardiovasc Med. 2003;13(1):15-21.
-
(2003)
Trends Cardiovasc Med
, vol.13
, Issue.1
, pp. 15-21
-
-
Rothermel, B.A.1
Vega, R.B.2
Williams, R.S.3
-
30
-
-
0034624137
-
Independent signals control expression of the calcineurin inhibitory proteins mcip1 and mcip2 in striated muscles
-
Yang J, Rothermel B, Vega RB, et al. Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circ Res. 2000;87(12): E61-E68.
-
(2000)
Circ Res
, vol.87
, Issue.12
, pp. E61-E68
-
-
Yang, J.1
Rothermel, B.2
Vega, R.B.3
-
31
-
-
0041732282
-
The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin
-
Ryeom S, Greenwald RJ, Sharpe AH, McKeon F. The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin. Nat Immunol. 2003;4(9):874-881.
-
(2003)
Nat Immunol.
, vol.4
, Issue.9
, pp. 874-881
-
-
Ryeom, S.1
Greenwald, R.J.2
Sharpe, A.H.3
McKeon, F.4
-
32
-
-
1642442672
-
Constitutive expression of the fk506 binding protein 51 (fkbp51) in bone marrow cells and megakaryocytes derived from idiopathic myelofibrosis and non-neoplastic haematopoiesis
-
Bock O, Neusch M, Büsche G, Mengel M, Kreipe H. Constitutive expression of the FK506 binding protein 51 (FKBP51) in bone marrow cells and megakaryocytes derived from idiopathic myelofibrosis and non-neoplastic haematopoiesis. Eur J Haematol. 2004;72(4):239-244.
-
(2004)
Eur J Haematol
, vol.72
, Issue.4
, pp. 239-244
-
-
Bock, O.1
Neusch, M.2
Büsche, G.3
Mengel, M.4
Kreipe, H.5
-
33
-
-
0033584231
-
Bcl-2-mediated drug resistance: Inhibition of apoptosis by blocking nuclear factor of activated t lymphocytes (nfat)-induced fas ligand transcription
-
Srivastava RK, Sasaki CY, Hardwick JM, Longo DL. Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription. J Exp Med. 1999;190(2):253-265.
-
(1999)
J Exp Med.
, vol.190
, Issue.2
, pp. 253-265
-
-
Srivastava, R.K.1
Sasaki, C.Y.2
Hardwick, J.M.3
Longo, D.L.4
-
34
-
-
0027390179
-
Presence and characteristics of circulating megakaryocyte progenitor cells in human fetal blood
-
Zauli G, Valvassori L, Capitani S. Presence and characteristics of circulating megakaryocyte progenitor cells in human fetal blood. Blood. 1993; 81(2):385-390.
-
(1993)
Blood
, vol.81
, Issue.2
, pp. 385-390
-
-
Zauli, G.1
Valvassori, L.2
Capitani, S.3
-
35
-
-
84862776981
-
Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis
-
Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science. 2012;335(6073): 1195-1200.
-
(2012)
Science
, vol.335
, Issue.6073
, pp. 1195-1200
-
-
Yuan, J.1
Nguyen, C.K.2
Liu, X.3
Kanellopoulou, C.4
Muljo, S.A.5
-
36
-
-
85022333397
-
Gene expression differences between fetal liver-derived and adult bone marrow-derived murine megakaryocyte progenitors: Implications for ds-tmd
-
Boston, MA: Children’s hospital Boston
-
Wieland KC, Cantor AB. Gene expression differences between fetal liver-derived and adult bone marrow-derived murine megakaryocyte progenitors: implications for DS-TMD. ASH 2008 Abstract. Boston, MA: Children’s hospital Boston 2008.
-
(2008)
ASH 2008 Abstract
-
-
Wieland, K.C.1
Cantor, A.B.2
-
37
-
-
0031948154
-
Effect of cyclosporin-a on anemia in idiopathic myelofibrosis
-
Falcone A, Musto P, Carotenuto M. Effect of cyclosporin-A on anemia in idiopathic myelofibrosis. Haematologica. 1998;83(7): 665-666.
-
(1998)
Haematologica
, vol.83
, Issue.7
, pp. 665-666
-
-
Falcone, A.1
Musto, P.2
Carotenuto, M.3
-
38
-
-
0030788763
-
Therapeutic effect of cyclosporine a in thrombocytopenia after myeloablative chemotherapy in acute myeloid leukaemia
-
Novik Y, Oleksowicz L, Wiernik PH. Therapeutic effect of cyclosporine A in thrombocytopenia after myeloablative chemotherapy in acute myeloid leukaemia. Med Oncol. 1997;14(1):43-46.
-
(1997)
Med Oncol.
, vol.14
, Issue.1
, pp. 43-46
-
-
Novik, Y.1
Oleksowicz, L.2
Wiernik, P.H.3
-
39
-
-
0028968405
-
Cyclosporin a therapy of immune-mediated thrombocytopenia in children
-
Schultz KR, Strahlendorf C, Warrier I, Ravindranath Y. Cyclosporin A therapy of immune-mediated thrombocytopenia in children. Blood. 1995;85(5):1406-1408.
-
(1995)
Blood
, vol.85
, Issue.5
, pp. 1406-1408
-
-
Schultz, K.R.1
Strahlendorf, C.2
Warrier, I.3
Ravindranath, Y.4
-
40
-
-
58149380865
-
Abnormalities in the myeloid progenitor compartment in down syndrome fetal liver precede acquisition of gata1 mutations
-
Tunstall-Pedoe O, Roy A, Karadimitris A, et al. Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations. Blood. 2008;112(12):4507-4511.
-
(2008)
Blood
, vol.112
, Issue.12
, pp. 4507-4511
-
-
Tunstall-Pedoe, O.1
Roy, A.2
Karadimitris, A.3
-
41
-
-
0029987146
-
Peripheral blood cell counts in infants with down’s syndrome
-
Kivivuori SM, Rajantie J, Siimes MA. Peripheral blood cell counts in infants with Down’s syndrome. Clin Genet. 1996;49(1):15-19.
-
(1996)
Clin Genet.
, vol.49
, Issue.1
, pp. 15-19
-
-
Kivivuori, S.M.1
Rajantie, J.2
Siimes, M.A.3
-
42
-
-
76449105998
-
Serum thrombopoietin level and thrombocytopenia during the neonatal period in infants with down’s syndrome
-
Matsubara K, Nigami H, Yura K, Inoue T, Isome K, Fukaya T. Serum thrombopoietin level and thrombocytopenia during the neonatal period in infants with Down’s syndrome. J Perinatol. 2010; 30(2):98-102.
-
(2010)
J Perinatol
, vol.30
, Issue.2
, pp. 98-102
-
-
Matsubara, K.1
Nigami, H.2
Yura, K.3
Inoue, T.4
Isome, K.5
Fukaya, T.6
-
43
-
-
38549131275
-
Extreme thrombocytosis associated with transient myeloproliferative disorder with down syndrome with t(11;17)(q13;q21)
-
Park ES, Kim SY, Yeom JS, Lim JY, Park CH, Youn HS. Extreme thrombocytosis associated with transient myeloproliferative disorder with Down Syndrome with t(11;17)(q13;q21). Pediatr Blood Cancer. 2008;50(3):643-644.
-
(2008)
Pediatr Blood Cancer
, vol.50
, Issue.3
, pp. 643-644
-
-
Park, E.S.1
Kim, S.Y.2
Yeom, J.S.3
Lim, J.Y.4
Park, C.H.5
Youn, H.S.6
-
44
-
-
33845990286
-
Hematological abnormalities during the first week of life among neonates with down syndrome: Data from a multihospital healthcare system
-
Henry E, Walker D, Wiedmeier SE, Christensen RD. Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system. Am J Med Genet A. 2007;143(1):42-50.
-
(2007)
Am J Med Genet A
, vol.143
, Issue.1
, pp. 42-50
-
-
Henry, E.1
Walker, D.2
Wiedmeier, S.E.3
Christensen, R.D.4
-
45
-
-
33646171446
-
Nfat dysregulation by increased dosage of dscr1 and dyrk1a on chromosome 21
-
Arron JR, Winslow MM, Polleri A, et al. NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature. 2006; 441(7093):595-600.
-
(2006)
Nature
, vol.441
, Issue.7093
, pp. 595-600
-
-
Arron, J.R.1
Winslow, M.M.2
Polleri, A.3
-
46
-
-
77953457835
-
Tumour angiogenesis is reduced in the tc1 mouse model of down’s syndrome
-
Reynolds LE, Watson AR, Baker M, et al. Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome. Nature. 2010;465(7299): 813-817.
-
(2010)
Nature
, vol.465
, Issue.7299
, pp. 813-817
-
-
Reynolds, L.E.1
Watson, A.R.2
Baker, M.3
|