메뉴 건너뛰기




Volumn 53, Issue 3, 2014, Pages 303-317

1,25-vitamin D3 promotes cardiac differentiation through modulation of the WNT signaling pathway

Author keywords

APC; Csnk1 1; Gsk3 ; VDR; Wnt11; catenin

Indexed keywords

CALCITRIOL; CASEIN KINASE IALPHA; CALCITRIOL RECEPTOR; COLECALCIFEROL;

EID: 84908367009     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-14-0168     Document Type: Article
Times cited : (33)

References (71)
  • 2
    • 67449150170 scopus 로고    scopus 로고
    • Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells
    • Artaza JN & Norris KC 2009 Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells. Journal of Endocrinology 200 207–221. doi:10.1677/JOE-08-0241
    • (2009) Journal of Endocrinology , vol.200 , pp. 207-221
    • Artaza, J.N.1    Norris, K.C.2
  • 4
    • 34547435196 scopus 로고    scopus 로고
    • Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse
    • Artaza JN, Reisz-Porszasz S, Dow JS, Kloner RA, Tsao J, Bhasin S & Gonzalez-Cadavid NF 2007 Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse. Journal of Endocrinology 194 63–76. doi:10.1677/JOE-07-0072
    • (2007) Journal of Endocrinology , vol.194 , pp. 63-76
    • Artaza, J.N.1    Reisz-Porszasz, S.2    Dow, J.S.3    Kloner, R.A.4    Tsao, J.5    Bhasin, S.6    Gonzalez-Cadavid, N.F.7
  • 5
    • 39749159662 scopus 로고    scopus 로고
    • Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts
    • Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J & Gonzalez-Cadavid NF 2008 Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts. Journal of Endocrinology 196 235–249. doi:10.1677/JOE-07-0408
    • (2008) Journal of Endocrinology , vol.196 , pp. 235-249
    • Artaza, J.N.1    Singh, R.2    Ferrini, M.G.3    Braga, M.4    Tsao, J.5    Gonzalez-Cadavid, N.F.6
  • 7
    • 76749119362 scopus 로고    scopus 로고
    • 3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells
    • 3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells. Journal of Steroid Biochemistry and Molecular Biology 119 73–83. doi:10.1016/j.jsbmb.2010.01.001
    • (2010) Journal of Steroid Biochemistry and Molecular Biology , vol.119 , pp. 73-83
    • Artaza, J.N.1    Sirad, F.2    Ferrini, M.G.3    Norris, K.C.4
  • 12
    • 78549292104 scopus 로고    scopus 로고
    • WNT signaling in adult cardiac hypertrophy and remodeling: Lessons learned from cardiac development
    • Bergmann MW.,2010 WNT signaling in adult cardiac hypertrophy and remodeling: lessons learned from cardiac development. Circulation Research 107 1198–1208. doi:10.1161/CIRCRESAHA.110.223768
    • (2010) Circulation Research , vol.107 , pp. 1198-1208
    • Bergmann, M.W.1
  • 13
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM & Nusse R 1997 Wnt signaling: a common theme in animal development. Genes and Development 11 3286–3305. doi:10.1101/gad.11.24.3286
    • (1997) Genes and Development , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 15
    • 33847053988 scopus 로고    scopus 로고
    • Cardiac hypertrophy and the Wnt/Frizzled pathway
    • Cingolani OH 2007 Cardiac hypertrophy and the Wnt/Frizzled pathway. Hypertension 49 427–428. doi:10.1161/01.HYP.0000255947.79237.61
    • (2007) Hypertension , vol.49 , pp. 427-428
    • Cingolani, O.H.1
  • 16
    • 84875058649 scopus 로고    scopus 로고
    • Role of the Wnt–Frizzled system in cardiac pathophysiology: A rapidly developing, poorly understood area with enormous potential
    • Dawson K, Aflaki M & Nattel S 2013 Role of the Wnt–Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential. Journal of Physiology 591 1409–1432. doi:10.1113/jphysiol.2012.235382
    • (2013) Journal of Physiology , vol.591 , pp. 1409-1432
    • Dawson, K.1    Aflaki, M.2    Nattel, S.3
  • 18
    • 33646203964 scopus 로고    scopus 로고
    • Wnt signal transduction and the formation of the myocardium
    • Eisenberg LM & Eisenberg CA 2006 Wnt signal transduction and the formation of the myocardium. Developmental Biology 293 305–315. doi:10.1016/j.ydbio.2006.02.014
    • (2006) Developmental Biology , vol.293 , pp. 305-315
    • Eisenberg, L.M.1    Eisenberg, C.A.2
  • 19
    • 33846857736 scopus 로고    scopus 로고
    • Evaluating the role of Wnt signal transduction in promoting the development of the heart
    • Eisenberg LM & Eisenberg CA 2007 Evaluating the role of Wnt signal transduction in promoting the development of the heart. Scientific World Journal 7 161–176. doi:10.1100/tsw.2007.71
    • (2007) Scientific World Journal , vol.7 , pp. 161-176
    • Eisenberg, L.M.1    Eisenberg, C.A.2
  • 20
    • 0030775143 scopus 로고    scopus 로고
    • Analysis of cell cycle-related Ki-67 and p120 expression by flow cytometric BrdUrd-Hoechst/7AAD and immunolabeling technique
    • Endl E, Steinbach P, Knuchel R & Hofstadter F 1997 Analysis of cell cycle-related Ki-67 and p120 expression by flow cytometric BrdUrd-Hoechst/7AAD and immunolabeling technique. Cytometry 29 233–241. doi:10.1002/(SICI)1097-0320(19971101)29:3!233::AID-CYTO6O3.0.CO;2-C
    • (1997) Cytometry , vol.29 , pp. 233-241
    • Endl, E.1    Steinbach, P.2    Knuchel, R.3    Hofstadter, F.4
  • 22
    • 60149110185 scopus 로고    scopus 로고
    • Noncanonical Wnt11 signaling and cardiomyogenic differentiation
    • Flaherty MP & Dawn B., 2008 Noncanonical Wnt11 signaling and cardiomyogenic differentiation. Trends in Cardiovascular Medicine 18 260–268. doi:10.1016/j.tcm.2008.12.001
    • (2008) Trends in Cardiovascular Medicine , vol.18 , pp. 260-268
    • Flaherty, M.P.1    Dawn, B.2
  • 23
    • 44049104628 scopus 로고    scopus 로고
    • Noncanonical Wnt11 signaling is sufficient to induce cardiomyogenic differentiation in unfractionated bone marrow mononuclear cells
    • Flaherty MP, Abdel-Latif A, Li Q, Hunt G, Ranjan S, Ou Q, Tang XL, Johnson RK, Bolli R & Dawn B 2008 Noncanonical Wnt11 signaling is sufficient to induce cardiomyogenic differentiation in unfractionated bone marrow mononuclear cells. Circulation 117 2241–2252. doi:10.1161/CIRCULATIONAHA.107.741066
    • (2008) Circulation , vol.117 , pp. 2241-2252
    • Flaherty, M.P.1    Abdel-Latif, A.2    Li, Q.3    Hunt, G.4    Ranjan, S.5    Ou, Q.6    Tang, X.L.7    Johnson, R.K.8    Bolli, R.9    Dawn, B.10
  • 27
    • 0020694123 scopus 로고
    • Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
    • Gerdes J, Schwab U, Lemke H & Stein H 1983 Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. International Journal of Cancer 31 13–20. doi:10.1002/ijc.2910310104
    • (1983) International Journal of Cancer , vol.31 , pp. 13-20
    • Gerdes, J.1    Schwab, U.2    Lemke, H.3    Stein, H.4
  • 28
    • 45149090726 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D and risk of myocardial infarction in men: A prospective study
    • Giovannucci E, Liu Y, Hollis BW & Rimm EB 2008 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Archives of Internal Medicine 168 1174–1180. doi:10.1001/archinte.168.11.1174
    • (2008) Archives of Internal Medicine , vol.168 , pp. 1174-1180
    • Giovannucci, E.1    Liu, Y.2    Hollis, B.W.3    Rimm, E.B.4
  • 29
    • 84859089706 scopus 로고    scopus 로고
    • Vitamin D deficiency is a predictor of reduced survival in patients with heart failure; vitamin D supplementation improves outcome
    • Gotsman I, Shauer A, Zwas DR, Hellman Y, Keren A, Lotan C & Admon D 2012 Vitamin D deficiency is a predictor of reduced survival in patients with heart failure; vitamin D supplementation improves outcome. European Journal of Heart Failure 14 357–366. doi:10.1093/eurjhf/hfr175
    • (2012) European Journal of Heart Failure , vol.14 , pp. 357-366
    • Gotsman, I.1    Shauer, A.2    Zwas, D.R.3    Hellman, Y.4    Keren, A.5    Lotan, C.6    Admon, D.7
  • 31
    • 77956288500 scopus 로고    scopus 로고
    • Inhibition of Wnt/b-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
    • Henderson WR, Chi EY, Ye X, Nguyen C, Tien YT, Zhou B, Borok Z, Knight DA & Kahn M 2010 Inhibition of Wnt/b-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. PNAS 107 14309–14314. doi:10.1073/pnas.1001520107
    • (2010) PNAS , vol.107 , pp. 14309-14314
    • Henderson, W.R.1    Chi, E.Y.2    Ye, X.3    Nguyen, C.4    Tien, Y.T.5    Zhou, B.6    Borok, Z.7    Knight, D.A.8    Kahn, M.9
  • 32
    • 84876436135 scopus 로고    scopus 로고
    • Circulating biomarkers for predicting cardiovascular disease risk; a systematic review and comprehensive overview of meta-analyses
    • van Holten TC, Waanders LF, de Groot PG, Vissers J, Hoefer IE, Pasterkamp G, Prins MW & Roest M 2013 Circulating biomarkers for predicting cardiovascular disease risk; a systematic review and comprehensive overview of meta-analyses. PLoS ONE 8 e62080. doi:10.1371/journal.pone.0062080
    • (2013) PLoS ONE , vol.8 , pp. e62080
    • Van Holten, T.C.1    Waanders, L.F.2    De Groot, P.G.3    Vissers, J.4    Hoefer, I.E.5    Pasterkamp, G.6    Prins, M.W.7    Roest, M.8
  • 33
    • 0024968476 scopus 로고
    • Stable cell membrane labeling
    • Horan PK & Slezak SE 1989 Stable cell membrane labeling. Nature 340 167–168. doi:10.1038/340167a0
    • (1989) Nature , vol.340 , pp. 167-168
    • Horan, P.K.1    Slezak, S.E.2
  • 36
    • 38149141662 scopus 로고    scopus 로고
    • Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: Results from the third National Health and Nutrition Examination Survey
    • Judd SE, Nanes MS, Ziegler TR, Wilson PW & Tangpricha V 2008 Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey. American Journal of Clinical Nutrition 87 136–141.
    • (2008) American Journal of Clinical Nutrition , vol.87 , pp. 136-141
    • Judd, S.E.1    Nanes, M.S.2    Ziegler, T.R.3    Wilson, P.W.4    Tangpricha, V.5
  • 37
    • 34547107319 scopus 로고    scopus 로고
    • WNT signaling pathway and stem cell signaling network
    • Review
    • Katoh M & Katoh M 2007 WNT signaling pathway and stem cell signaling network. Clinical Cancer Research 13 4042–4045. Review. doi:10.1158/1078-0432.CCR-06-2316
    • (2007) Clinical Cancer Research , vol.13 , pp. 4042-4045
    • Katoh, M.1    Katoh, M.2
  • 38
    • 67349254810 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey
    • Kendrick J, Targher G, Smits G & Chonchol M 2009 25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey. Atherosclerosis 205 255–260. doi:10.1016/j.atherosclerosis.2008.10.033
    • (2009) Atherosclerosis , vol.205 , pp. 255-260
    • Kendrick, J.1    Targher, G.2    Smits, G.3    Chonchol, M.4
  • 40
    • 56349169572 scopus 로고    scopus 로고
    • Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004)
    • Kim DH, Sabour S, Sagar UN, Adams S & Whellan DJ 2008 Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). American Journal of Cardiology 102 1540–1544. doi:10.1016/j.amjcard.2008.06.067
    • (2008) American Journal of Cardiology , vol.102 , pp. 1540-1544
    • Kim, D.H.1    Sabour, S.2    Sagar, U.N.3    Adams, S.4    Whellan, D.J.5
  • 41
    • 0017232346 scopus 로고
    • Properties of a clonal muscle cell line from rat heart
    • Kimes BW & Brandt BL 1976 Properties of a clonal muscle cell line from rat heart. Experimental Cell Research 98 367–381. doi:10.1016/0014-4827(76)90447-X
    • (1976) Experimental Cell Research , vol.98 , pp. 367-381
    • Kimes, B.W.1    Brandt, B.L.2
  • 42
    • 34250800027 scopus 로고    scopus 로고
    • Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors
    • Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR & Srivastava D 2007 Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. PNAS 104 10894–10899. doi:10.1073/pnas.0704044104
    • (2007) PNAS , vol.104 , pp. 10894-10899
    • Kwon, C.1    Arnold, J.2    Hsiao, E.C.3    Taketo, M.M.4    Conklin, B.R.5    Srivastava, D.6
  • 43
    • 84856371983 scopus 로고    scopus 로고
    • Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: A structure–activity relationship study based on inhibitors for the Wnt response
    • Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M & Cashman JR 2012 Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure–activity relationship study based on inhibitors for the Wnt response. Journal of Medicinal Chemistry 55 697–708. doi:10.1021/jm2010223
    • (2012) Journal of Medicinal Chemistry , vol.55 , pp. 697-708
    • Lanier, M.1    Schade, D.2    Willems, E.3    Tsuda, M.4    Spiering, S.5    Kalisiak, J.6    Mercola, M.7    Cashman, J.R.8
  • 44
    • 34250346886 scopus 로고    scopus 로고
    • Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: Data from the Third National Health and Nutrition Examination Survey
    • Martins D, Wolf M, Pan D, Zadshir A, Tareen N, Thadhani R, Felsenfeld A, Levine B, Mehrotra R & Norris K 2007 Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine 167 1159–1165. doi:10.1001/archinte.167.11.1159
    • (2007) Archives of Internal Medicine , vol.167 , pp. 1159-1165
    • Martins, D.1    Wolf, M.2    Pan, D.3    Zadshir, A.4    Tareen, N.5    Thadhani, R.6    Felsenfeld, A.7    Levine, B.8    Mehrotra, R.9    Norris, K.10
  • 45
    • 84908372504 scopus 로고    scopus 로고
    • The effect of short term vitamin D supplementation on the inflammatory and oxidative mediators of arterial stiffness
    • Martins D, Meng Y, Tareen N, Artaza J, Lee JE, Farodolu C, Gibbons G & Norris K 2014 The effect of short term vitamin D supplementation on the inflammatory and oxidative mediators of arterial stiffness. Health 6 1503–1511. doi:10.4236/health.2014.612185
    • (2014) Health , vol.6 , pp. 1503-1511
    • Martins, D.1    Meng, Y.2    Tareen, N.3    Artaza, J.4    Lee, J.E.5    Farodolu, C.6    Gibbons, G.7    Norris, K.8
  • 46
  • 48
    • 44849087389 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: Results from NHANES 2001 to 2004. Arteriosclerosis
    • Melamed ML, Muntner P, Michos ED, Uribarri J, Weber C, Sharma J & Raggi P 2008 Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004. Arteriosclerosis, Thrombosis, and Vascular Biology 28 1179–1185. doi:10.1161/ATVBAHA.108.165886
    • (2008) Thrombosis, and Vascular Biology , vol.28 , pp. 1179-1185
    • Melamed, M.L.1    Muntner, P.2    Michos, E.D.3    Uribarri, J.4    Weber, C.5    Sharma, J.6    Raggi, P.7
  • 49
    • 0037423671 scopus 로고    scopus 로고
    • Myocyte death, growth and regeneration in cardiac hypertrophy and failure
    • Nadal-Ginard B, Kajstura J, Leri A & Anversa P 2003 Myocyte death, growth and regeneration in cardiac hypertrophy and failure. Circulation Research 92 139–150. doi:10.1161/01.RES.0000053618.86362.DF
    • (2003) Circulation Research , vol.92 , pp. 139-150
    • Nadal-Ginard, B.1    Kajstura, J.2    Leri, A.3    Anversa, P.4
  • 50
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/b-catenin signaling in cardiomyogenesis and hematopoiesis
    • Naito T, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A & Komuro I 2006 Developmental stage-specific biphasic roles of Wnt/b-catenin signaling in cardiomyogenesis and hematopoiesis. PNAS 103 19812–19817. doi:10.1073/pnas.0605768103
    • (2006) PNAS , vol.103 , pp. 19812-19817
    • Naito, T.1    Shiojima, I.2    Akazawa, H.3    Hidaka, K.4    Morisaki, T.5    Kikuchi, A.6    Komuro, I.7
  • 53
    • 33751537194 scopus 로고    scopus 로고
    • Minireview: Vitamin D receptor: New assignments for an already busy receptor
    • Norman AW 2006 Minireview: vitamin D receptor: new assignments for an already busy receptor. Endocrinology 147 5542–5548. doi:10.1210/en.2006-0946
    • (2006) Endocrinology , vol.147 , pp. 5542-5548
    • Norman, A.W.1
  • 59
    • 0036733284 scopus 로고    scopus 로고
    • Caveolae: From cell biology to animal physiology
    • Razani B, Woodman SE & Lisanti MP 2002 Caveolae: from cell biology to animal physiology. Pharmacological Reviews 54 431–467. doi:10.1124/pr.54.3.431
    • (2002) Pharmacological Reviews , vol.54 , pp. 431-467
    • Razani, B.1    Woodman, S.E.2    Lisanti, M.P.3
  • 60
    • 77649342305 scopus 로고    scopus 로고
    • Molecular targets and regulators of cardiac hypertrophy
    • Rohini A, Agrawal N, Koyani CN & Singh R 2010 Molecular targets and regulators of cardiac hypertrophy. Pharmacological Research 61 269–280. doi:10.1016/j.phrs.2009.11.012
    • (2010) Pharmacological Research , vol.61 , pp. 269-280
    • Rohini, A.1    Agrawal, N.2    Koyani, C.N.3    Singh, R.4
  • 61
    • 84862262717 scopus 로고    scopus 로고
    • Arrhythmogenic implications of fibroblast–myocyte interactions. Circulation
    • Rohr S 2012 Arrhythmogenic implications of fibroblast–myocyte interactions. Circulation. Arrhythmia and Electrophysiology 5 442–452. doi:10.1161/CIRCEP.110.957647
    • (2012) Arrhythmia and Electrophysiology , vol.5 , pp. 442-452
    • Rohr, S.1
  • 62
    • 34250643090 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D, ethnicity, and blood pressure in the Third National Health and Nutrition Examination Survey
    • Scragg R, Sowers M & Bell C 2007 Serum 25-hydroxyvitamin D, ethnicity, and blood pressure in the Third National Health and Nutrition Examination Survey. American Journal of Hypertension 20 713–719. doi:10.1016/j.amjhyper.2007.01.017
    • (2007) American Journal of Hypertension , vol.20 , pp. 713-719
    • Scragg, R.1    Sowers, M.2    Bell, C.3
  • 65
    • 38549151870 scopus 로고    scopus 로고
    • Functional vitamin D receptor (VDR) in the t-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility
    • Tishkoff DX, Nibbelink KA, Holmberg KH, Dandu L & Simpson RU 2008 Functional vitamin D receptor (VDR) in the t-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility. Endocrinology 149 558–564. doi:10.1210/en.2007-0805
    • (2008) Endocrinology , vol.149 , pp. 558-564
    • Tishkoff, D.X.1    Nibbelink, K.A.2    Holmberg, K.H.3    Dandu, L.4    Simpson, R.U.5
  • 66
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/b-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • Ueno S, Weidinger G, Osugi T, Kohn AD, Golob JL, Pabon L, Reinecke H, Moon RT & Murry CE 2007 Biphasic role for Wnt/b-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. PNAS 104 9685–9690. doi:10.1073/pnas.0702859104
    • (2007) PNAS , vol.104 , pp. 9685-9690
    • Ueno, S.1    Weidinger, G.2    Osugi, T.3    Kohn, A.D.4    Golob, J.L.5    Pabon, L.6    Reinecke, H.7    Moon, R.T.8    Murry, C.E.9
  • 70
    • 80051796581 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm
    • Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J & Mercola M 2011 Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circulation Research 109 360–364. doi:10.1161/CIRCRESAHA.111.249540
    • (2011) Circulation Research , vol.109 , pp. 360-364
    • Willems, E.1    Spiering, S.2    Davidovics, H.3    Lanier, M.4    Xia, Z.5    Dawson, M.6    Cashman, J.7    Mercola, M.8
  • 71
    • 84865336270 scopus 로고    scopus 로고
    • Efficient cardiomyogenic differentiation of bone marrow mesenchymal stromal cells by combination of Wnt11 and bone morphogenetic protein 2
    • Zhang Z, Li H, Ma Z, Feng J, Gao P, Dong H & Zhang Z 2012 Efficient cardiomyogenic differentiation of bone marrow mesenchymal stromal cells by combination of Wnt11 and bone morphogenetic protein 2. Experimental Biology and Medicine 237 768–776. doi:10.1258/ebm.2012.011291
    • (2012) Experimental Biology and Medicine , vol.237 , pp. 768-776
    • Zhang, Z.1    Li, H.2    Ma, Z.3    Feng, J.4    Gao, P.5    Dong, H.6    Zhang, Z.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.